Project measure / variable:   Schoonjans1   oxo_CA_plasma_t0_CD

ID, description, units MPD:112646   oxo_CA_plasma_t0_CD   plasma bile acid 3-oxocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   13 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 3-oxocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested13 strains
Mean of the strain means7.9248   ng/mL
Median of the strain means6.632   ng/mL
SD of the strain means± 4.3575
Coefficient of variation (CV)0.5499
Min–max range of strain means2.708   –   19.096   ng/mL
Mean sample size per strain2.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 9 453.9754 50.4417 1.4127 0.2448
Residuals 21 749.8029 35.7049


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 8.7176 0.0   1   0.0 0.0 8.7176, 8.7176 0.18
BXD32 m 5.744 2.7698   3 1.5991 0.4822 4.11, 8.942 -0.5
BXD34 m 6.632 1.8919   3 1.0923 0.2853 4.622, 8.378 -0.3
BXD40 m 6.396 2.0577   3 1.188 0.3217 5.204, 8.772 -0.35
BXD45 m 2.708 0.0   1   0.0 0.0 2.708, 2.708 -1.2
BXD49 m 19.096 4.6839   2   3.312 0.2453 15.784, 22.408 2.56
BXD53 m 4.206 0.0   1   0.0 0.0 4.206, 4.206 -0.85
BXD55 m 5.862 4.6047   2   3.256 0.7855 2.606, 9.118 -0.47
BXD6 m 13.598 6.9165   4 3.4583 0.5087 5.77, 20.846 1.3
BXD73 m 8.051 3.025   2   2.139 0.3757 5.912, 10.19 0.03
BXD77 m 4.7927 3.1537   3 1.8208 0.658 2.938, 8.434 -0.72
BXD87 m 10.256 9.6562   5 4.3184 0.9415 5.298, 27.49 0.53
C57BL/6J m 6.9635 6.587   4 3.2935 0.9459 2.786, 16.666 -0.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD32 m 5.744 3.4498743172 12.9184063925 -1.4304063925
BXD34 m 6.632 3.4498743172 13.8064063925 -0.5424063925
BXD40 m 6.396 3.4498743172 13.5704063925 -0.7784063925
BXD49 m 19.096 4.2252158769 27.8828174346 10.3091825654
BXD55 m 5.862 4.2252158769 14.6488174346 -2.9248174346
BXD6 m 13.5975 2.9876787985 19.810718193 7.384281807
BXD73 m 8.051 4.2252158769 16.8378174346 -0.7358174346
BXD77 m 4.7926666667 3.4498743172 11.9670730592 -2.3817397259
BXD87 m 10.256 2.6722611554 15.8132712955 4.6987287045
C57BL/6J m 6.9635 2.9876787985 13.176718193 0.750281807




  GWAS USING LINEAR MIXED MODELS