Project measure / variable:   Schoonjans1   gluc_kinetic_t60_HFD

ID, description, units MPD:112645   gluc_kinetic_t60_HFD   glucose, glucose kinetic test (Ensure Plus oral gavage, overday fast), at 20 wks of age, after 60 min   [mmol/L]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Schoonjans1 - glucose, glucose kinetic test (Ensure Plus oral gavage, overday fast), at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means276.9   mmol/L
Median of the strain means257.0   mmol/L
SD of the strain means± 81.54
Coefficient of variation (CV)0.2944
Min–max range of strain means168.8   –   474.8   mmol/L
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 1116744.5301 31906.9866 6.939 < 0.0001
Residuals 135 620759.5167 4598.2186


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 225.2 155.6   5 69.57 0.6908 133.0, 501.0 -0.63
BXD100 m 201.2 24.157   4 12.079 0.12 171.0, 230.0 -0.93
BXD11 m 324.7 167.9   3 96.92 0.5171 194.0, 514.0 0.59
BXD12 m 213.5 31.89   4 15.945 0.1494 184.0, 244.0 -0.78
BXD27 m 448.2 117.0   5 52.33 0.2611 261.0, 582.0 2.1
BXD32 m 209.5 19.774   4 9.8869 0.0944 185.0, 227.0 -0.83
BXD34 m 250.4 35.232   5 15.756 0.1407 199.0, 286.0 -0.33
BXD39 m 276.2 113.5   5 50.76 0.4109 195.0, 470.0 -0.01
BXD40 m 241.5 40.764   4 20.382 0.1688 213.0, 302.0 -0.43
BXD43 m 274.8 68.84   5 30.785 0.2505 194.0, 348.0 -0.03
BXD45 m 258.6 17.315   5 7.7434 0.067 230.0, 274.0 -0.22
BXD48 m 327.4 79.08   5 35.365 0.2415 267.0, 455.0 0.62
BXD48a m 326.8 47.908   5 21.425 0.1466 255.0, 388.0 0.61
BXD49 m 196.2 10.232   5 4.576 0.0522 185.0, 213.0 -0.99
BXD51 m 295.8 60.8   5 27.191 0.2055 223.0, 368.0 0.23
BXD53 m 369.8 41.451   5 18.538 0.1121 326.0, 432.0 1.14
BXD55 m 188.4 30.262   5 13.534 0.1606 141.0, 215.0 -1.09
BXD6 m 225.6 32.331   5 14.459 0.1433 170.0, 251.0 -0.63
BXD62 m 255.4 28.571   5 12.777 0.1119 216.0, 280.0 -0.26
BXD63 m 200.6 13.686   5 6.1205 0.0682 180.0, 211.0 -0.94
BXD64 m 438.6 84.87   5 37.955 0.1935 312.0, 536.0 1.98
BXD66 m 168.8 10.782   4 5.391 0.0639 153.0, 177.0 -1.33
BXD67 m 340.4 90.69   5 40.557 0.2664 216.0, 466.0 0.78
BXD69 m 375.8 125.0   5 55.92 0.3327 226.0, 510.0 1.21
BXD73 m 241.4 40.538   5 18.129 0.1679 197.0, 304.0 -0.44
BXD75 m 229.0 36.572   5 16.355 0.1597 184.0, 275.0 -0.59
BXD77 m 262.6 72.01   5 32.205 0.2742 198.0, 378.0 -0.18
BXD79 m 433.0 88.42   5 39.544 0.2042 354.0, 561.0 1.91
BXD8 m 249.6 62.68   5 28.033 0.2511 192.0, 338.0 -0.34
BXD81 m 279.0 32.381   5 14.481 0.1161 241.0, 322.0 0.03
BXD84 m 474.8 80.69   5 36.087 0.1699 373.0, 595.0 2.43
BXD87 m 217.2 16.008   4 8.0039 0.0737 202.0, 233.0 -0.73
BXD89 m 187.4 12.239   5 5.4736 0.0653 172.0, 200.0 -1.1
BXD90 m 175.0 28.577   4 14.289 0.1633 133.0, 194.0 -1.25
C57BL/6J m 259.6 31.134   5 13.923 0.1199 216.0, 294.0 -0.21
DBA/2J m 327.8 61.03   5 27.294 0.1862 263.0, 394.0 0.62


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 225.2 30.325628244 285.1747607806 165.2252392194
BXD100 m 201.25 33.905083107 268.3038210199 134.1961789801
BXD11 m 324.6666666667 39.1502177175 402.0937498987 247.2395834346
BXD12 m 213.5 33.905083107 280.5538210199 146.4461789801
BXD27 m 448.2 30.325628244 508.1747607806 388.2252392194
BXD32 m 209.5 33.905083107 276.5538210199 142.4461789801
BXD34 m 250.4 30.325628244 310.3747607806 190.4252392194
BXD39 m 276.2 30.325628244 336.1747607806 216.2252392194
BXD40 m 241.5 33.905083107 308.5538210199 174.4461789801
BXD43 m 274.8 30.325628244 334.7747607806 214.8252392194
BXD45 m 258.6 30.325628244 318.5747607806 198.6252392194
BXD48 m 327.4 30.325628244 387.3747607806 267.4252392194
BXD48a m 326.8 30.325628244 386.7747607806 266.8252392194
BXD49 m 196.2 30.325628244 256.1747607806 136.2252392194
BXD51 m 295.8 30.325628244 355.7747607806 235.8252392194
BXD53 m 369.8 30.325628244 429.7747607806 309.8252392194
BXD55 m 188.4 30.325628244 248.3747607806 128.4252392194
BXD6 m 225.6 30.325628244 285.5747607806 165.6252392194
BXD62 m 255.4 30.325628244 315.3747607806 195.4252392194
BXD63 m 200.6 30.325628244 260.5747607806 140.6252392194
BXD64 m 438.6 30.325628244 498.5747607806 378.6252392194
BXD66 m 168.75 33.905083107 235.8038210199 101.6961789801
BXD67 m 340.4 30.325628244 400.3747607806 280.4252392194
BXD69 m 375.8 30.325628244 435.7747607806 315.8252392194
BXD73 m 241.4 30.325628244 301.3747607806 181.4252392194
BXD75 m 229.0 30.325628244 288.9747607806 169.0252392194
BXD77 m 262.6 30.325628244 322.5747607806 202.6252392194
BXD79 m 433.0 30.325628244 492.9747607806 373.0252392194
BXD8 m 249.6 30.325628244 309.5747607806 189.6252392194
BXD81 m 279.0 30.325628244 338.9747607806 219.0252392194
BXD84 m 474.8 30.325628244 534.7747607806 414.8252392194
BXD87 m 217.25 33.905083107 284.3038210199 150.1961789801
BXD89 m 187.4 30.325628244 247.3747607806 127.4252392194
BXD90 m 175.0 33.905083107 242.0538210199 107.9461789801
C57BL/6J m 259.6 30.325628244 319.5747607806 199.6252392194
DBA/2J m 327.8 30.325628244 387.7747607806 267.8252392194




  GWAS USING LINEAR MIXED MODELS