Project measure / variable:   CSNA03   goodness_of_fit_cc

ID, description, units MPD:112548   goodness_of_fit_cc   percentage of observed rhythms that fit expected sine wave, indicating stability and robustness of circadian rhythm, in fibroblast cultures, CC   [%]  
Data set, strains CSNA03   CC w/par   40 strains     sex: both     age: 8-12wks
Procedure in vitro assay
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  STRAIN COMPARISON PLOT
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CSNA03 - percentage of observed rhythms that fit expected sine wave, indicating stability and robustness of circadian rhythm, in fibroblast cultures, CC



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested35 strains34 strains
Mean of the strain means78.53   % 79.67   %
Median of the strain means81.08   % 80.87   %
SD of the strain means± 9.7241 ± 7.1001
Coefficient of variation (CV)0.1238 0.0891
Min–max range of strain means50.25   –   93.69   % 64.1   –   93.27   %
Mean sample size per strain3.9   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 15.2171 15.2171 0.263 0.6087
strain 23 8138.7098 353.8569 6.1152 < 0.0001
sex:strain 23 1471.0458 63.9585 1.1053 0.3421
Residuals 197 11399.3819 57.8649


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 82.51 8.2546   10 2.6103 0.1 73.29, 91.96 0.41
129S1/SvImJ m 77.4 8.7219   9 2.9073 0.1127 67.56, 90.79 -0.32
A/J f 82.16 2.7478   9 0.91593 0.0334 78.21, 87.17 0.37
A/J m 80.97 2.4969   10 0.78958 0.0308 77.39, 85.1 0.18
C57BL/6J f 81.08 9.3688   10 2.9627 0.1156 66.49, 91.91 0.26
C57BL/6J m 81.86 7.6814   10 2.4291 0.0938 64.21, 92.55 0.31
CAST/EiJ f 93.69 1.3937   10 0.44074 0.0149 91.01, 95.28 1.56
CAST/EiJ m 93.27 1.547   10 0.48919 0.0166 90.45, 94.58 1.92
CC001/UncJ f 87.25 4.7447   2   3.355 0.0544 83.9, 90.61 0.9
CC001/UncJ m 90.13 0.0   1   0.0 0.0 90.13, 90.13 1.47
CC002/UncJ f 82.55 1.3152   2   0.93 0.0159 81.62, 83.48 0.41
CC002/UncJ m 89.65 3.479   2   2.46 0.0388 87.19, 92.11 1.41
CC003/UncJ f 50.25 0.0   1   0.0 0.0 50.25, 50.25 -2.91
CC004/TauUncJ f 84.46 3.0547   2   2.16 0.0362 82.3, 86.62 0.61
CC004/TauUncJ m 89.05 0.13435   2   0.095 0.0015 88.95, 89.14 1.32
CC005/TauUncJ f 86.36 6.0872   4 3.0436 0.0705 77.35, 90.59 0.81
CC005/TauUncJ m 85.11 6.4014   3 3.6959 0.0752 77.8, 89.7 0.77
CC008/GeniUncJ f 61.72 31.732   2   22.438 0.5141 39.284, 84.16 -1.73
CC008/GeniUncJ m 69.4 12.176   2   8.61 0.1755 60.79, 78.01 -1.45
CC010/GeniUncJ m 81.15 3.1325   2   2.215 0.0386 78.93, 83.36 0.21
CC011/UncJ f 89.16 3.5375   3 2.0424 0.0397 85.08, 91.37 1.09
CC011/UncJ m 80.77 8.3763   6 3.4196 0.1037 72.9, 91.91 0.16
CC012/GeniUncJ f 88.37 6.0431   5 2.7026 0.0684 78.87, 92.62 1.01
CC012/GeniUncJ m 80.65 14.003   6 5.7166 0.1736 62.15, 93.7 0.14
CC013/GeniUncJ f 74.46 17.856   3 10.309 0.2398 54.11, 87.52 -0.42
CC013/GeniUncJ m 73.56 18.54   2   13.11 0.252 60.45, 86.67 -0.86
CC016/GeniUncJ f 83.48 2.8143   2   1.99 0.0337 81.49, 85.47 0.51
CC016/GeniUncJ m 67.3 3.981   2   2.815 0.0592 64.48, 70.11 -1.74
CC017/UncJ m 81.94 4.725   3 2.728 0.0577 77.23, 86.68 0.32
CC018/UncJ f 73.67 10.55   2   7.46 0.1432 66.21, 81.13 -0.5
CC018/UncJ m 84.48 1.4684   3 0.84779 0.0174 82.81, 85.58 0.68
CC019/TauUncJ f 86.19 9.2764   3 5.3558 0.1076 75.57, 92.71 0.79
CC019/TauUncJ m 83.33 3.578   2   2.53 0.0429 80.8, 85.86 0.52
CC023/GeniUncJ f 62.78 3.2244   2   2.28 0.0514 60.5, 65.06 -1.62
CC023/GeniUncJ m 78.5 9.9773   2   7.055 0.1271 71.45, 85.56 -0.16
CC025/GeniUncJ f 73.06 9.1413   5 4.0881 0.1251 58.12, 81.6 -0.56
CC025/GeniUncJ m 75.95 7.4749   4 3.7375 0.0984 68.78, 82.85 -0.52
CC028/GeniUncJ f 90.18 3.3342   3 1.925 0.037 86.39, 92.65 1.2
CC028/GeniUncJ m 87.14 5.5603   3 3.2103 0.0638 80.82, 91.28 1.05
CC030/GeniUncJ f 73.55 12.82   2   9.065 0.1743 64.48, 82.61 -0.51
CC030/GeniUncJ m 72.14 0.0   1   0.0 0.0 72.14, 72.14 -1.06
CC035/UncJ f 85.87 0.0   1   0.0 0.0 85.87, 85.87 0.76
CC037/TauUncJ f 83.35 0.0   1   0.0 0.0 83.35, 83.35 0.5
CC041/TauUncJ f 83.2 5.3303   4 2.6651 0.0641 75.9, 87.77 0.48
CC041/TauUncJ m 82.77 5.4014   6 2.2051 0.0653 75.97, 90.06 0.44
CC043/GeniUncJ m 75.13 0.0   1   0.0 0.0 75.13, 75.13 -0.64
CC051/TauUncJ f 77.46 0.0   1   0.0 0.0 77.46, 77.46 -0.11
CC051/TauUncJ m 73.34 0.0   1   0.0 0.0 73.34, 73.34 -0.89
CC057/UncJ f 70.79 0.0   1   0.0 0.0 70.79, 70.79 -0.8
CC059/TauUncJ f 79.65 13.871   4 6.9357 0.1741 59.32, 90.58 0.12
CC061/GeniUncJ f 58.85 0.0   1   0.0 0.0 58.85, 58.85 -2.02
CC061/GeniUncJ m 73.03 9.9349   2   7.025 0.136 66.01, 80.06 -0.93
CC068/TauUncJ f 80.76 0.0   1   0.0 0.0 80.76, 80.76 0.23
CC074/UncJ m 86.88 0.0   1   0.0 0.0 86.88, 86.88 1.02
CC075/UncJ f 73.96 19.247   2   13.61 0.2602 60.35, 87.57 -0.47
CC075/UncJ m 80.25 11.724   3 6.7689 0.1461 68.12, 91.52 0.08
CC078/TauUncJ m 64.1 0.0   1   0.0 0.0 64.1, 64.1 -2.19
CC080/TauUncJ f 66.73 0.0   1   0.0 0.0 66.73, 66.73 -1.21
CC080/TauUncJ m 69.16 0.0   1   0.0 0.0 69.16, 69.16 -1.48
CC084/TauJ f 73.4 13.548   2   9.58 0.1846 63.82, 82.98 -0.53
CC084/TauJ m 72.19 12.912   2   9.13 0.1789 63.06, 81.32 -1.05
NOD/ShiLtJ f 75.44 6.8848   9 2.2949 0.0913 68.38, 86.62 -0.32
NOD/ShiLtJ m 75.03 6.8402   10 2.1631 0.0912 65.95, 85.99 -0.65
NZO/HlLtJ f 84.02 6.7595   8 2.3899 0.0805 73.3, 93.86 0.56
NZO/HlLtJ m 82.75 3.4839   7 1.3168 0.0421 79.6, 89.8 0.43
PWK/PhJ f 89.81 2.1808   10 0.68962 0.0243 86.83, 93.49 1.16
PWK/PhJ m 86.68 4.2131   10 1.3323 0.0486 77.13, 90.94 0.99
WSB/EiJ f 78.23 11.02   9 3.6734 0.1409 65.38, 92.02 -0.03
WSB/EiJ m 83.56 5.7541   8 2.0344 0.0689 73.11, 90.29 0.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 82.513 2.4055120563 87.2568598918 77.7691401082
129S1/SvImJ m 77.3955555556 2.5356323457 82.3960229418 72.3950881693
A/J f 82.1555555556 2.5356323457 87.1560229418 77.1550881693
A/J m 80.967 2.4055120563 85.7108598918 76.2231401082
C57BL/6J f 81.078 2.4055120563 85.8218598918 76.3341401082
C57BL/6J m 81.861 2.4055120563 86.6048598918 77.1171401082
CAST/EiJ f 93.691 2.4055120563 98.4348598918 88.9471401082
CAST/EiJ m 93.268 2.4055120563 98.0118598918 88.5241401082
CC002/UncJ f 82.55 5.3788884787 93.1575931938 71.9424068062
CC002/UncJ m 89.65 5.3788884787 100.2575931938 79.0424068062
CC004/TauUncJ f 84.46 5.3788884787 95.0675931938 73.8524068062
CC004/TauUncJ m 89.045 5.3788884787 99.6525931938 78.4374068062
CC005/TauUncJ f 86.3625 3.8034485185 93.8632010794 78.8617989206
CC005/TauUncJ m 85.1133333333 4.391844052 93.7743969079 76.4522697587
CC008/GeniUncJ f 61.722 5.3788884787 72.3295931938 51.1144068062
CC008/GeniUncJ m 69.4 5.3788884787 80.0075931938 58.7924068062
CC011/UncJ f 89.16 4.391844052 97.8210635746 80.4989364254
CC011/UncJ m 80.7733333333 3.1055027111 86.8976301192 74.6490365474
CC012/GeniUncJ f 88.368 3.4019077745 95.076830997 81.659169003
CC012/GeniUncJ m 80.6483333333 3.1055027111 86.7726301192 74.5240365474
CC013/GeniUncJ f 74.4566666667 4.391844052 83.1177302413 65.7956030921
CC013/GeniUncJ m 73.56 5.3788884787 84.1675931938 62.9524068062
CC016/GeniUncJ f 83.48 5.3788884787 94.0875931938 72.8724068062
CC016/GeniUncJ m 67.295 5.3788884787 77.9025931938 56.6874068062
CC018/UncJ f 73.67 5.3788884787 84.2775931938 63.0624068062
CC018/UncJ m 84.4766666667 4.391844052 93.1377302413 75.8156030921
CC019/TauUncJ f 86.19 4.391844052 94.8510635746 77.5289364254
CC019/TauUncJ m 83.33 5.3788884787 93.9375931938 72.7224068062
CC023/GeniUncJ f 62.78 5.3788884787 73.3875931938 52.1724068062
CC023/GeniUncJ m 78.505 5.3788884787 89.1125931938 67.8974068062
CC025/GeniUncJ f 73.062 3.4019077745 79.770830997 66.353169003
CC025/GeniUncJ m 75.955 3.8034485185 83.4557010794 68.4542989206
CC028/GeniUncJ f 90.1833333333 4.391844052 98.8443969079 81.5222697587
CC028/GeniUncJ m 87.14 4.391844052 95.8010635746 78.4789364254
CC041/TauUncJ f 83.2 3.8034485185 90.7007010794 75.6992989206
CC041/TauUncJ m 82.7733333333 3.1055027111 88.8976301192 76.6490365474
CC075/UncJ f 73.96 5.3788884787 84.5675931938 63.3524068062
CC075/UncJ m 80.2533333333 4.391844052 88.9143969079 71.5922697587
CC084/TauJ f 73.4 5.3788884787 84.0075931938 62.7924068062
CC084/TauJ m 72.19 5.3788884787 82.7975931938 61.5824068062
NOD/ShiLtJ f 75.4433333333 2.5356323457 80.4438007196 70.4428659471
NOD/ShiLtJ m 75.028 2.4055120563 79.7718598918 70.2841401082
NZO/HlLtJ f 84.02 2.6894442393 89.3237965969 78.7162034031
NZO/HlLtJ m 82.7485714286 2.8751368298 88.4185684899 77.0785743672
PWK/PhJ f 89.813 2.4055120563 94.5568598918 85.0691401082
PWK/PhJ m 86.678 2.4055120563 91.4218598918 81.9341401082
WSB/EiJ f 78.2344444444 2.5356323457 83.2349118307 73.2339770582
WSB/EiJ m 83.565 2.6894442393 88.8687965969 78.2612034031


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 79.9542777778 1.7475639935 83.4006120896 76.507943466
A/J both 81.5612777778 1.7475639935 85.0076120896 78.114943466
C57BL/6J both 81.4695 1.7009538873 84.8239154985 78.1150845015
CAST/EiJ both 93.4795 1.7009538873 96.8339154985 90.1250845015
CC002/UncJ both 86.1 3.8034485185 93.6007010794 78.5992989206
CC004/TauUncJ both 86.7525 3.8034485185 94.2532010794 79.2517989206
CC005/TauUncJ both 85.7379166667 2.9049317896 91.4666717436 80.0091615897
CC008/GeniUncJ both 65.561 3.8034485185 73.0617010794 58.0602989206
CC011/UncJ both 84.9666666667 2.6894442393 90.2704632636 79.6628700698
CC012/GeniUncJ both 84.5081666667 2.3031024508 89.0500667225 79.9662666109
CC013/GeniUncJ both 74.0083333333 3.4720575832 80.8555052971 67.1611613695
CC016/GeniUncJ both 75.3875 3.8034485185 82.8882010794 67.8867989206
CC018/UncJ both 79.0733333333 3.4720575832 85.9205052971 72.2261613695
CC019/TauUncJ both 84.76 3.4720575832 91.6071719638 77.9128280362
CC023/GeniUncJ both 70.6425 3.8034485185 78.1432010794 63.1417989206
CC025/GeniUncJ both 74.5085 2.5514308309 79.5401232477 69.4768767523
CC028/GeniUncJ both 88.6616666667 3.1055027111 94.7859634526 82.5373698808
CC041/TauUncJ both 82.9866666667 2.4551154617 87.8283483942 78.1449849391
CC075/UncJ both 77.1066666667 3.4720575832 83.9538386305 70.2594947029
CC084/TauJ both 72.795 3.8034485185 80.2957010794 65.2942989206
NOD/ShiLtJ both 75.2356666667 1.7475639935 78.6820009784 71.7893323549
NZO/HlLtJ both 83.3842857143 1.968471622 87.2662673286 79.5023040999
PWK/PhJ both 88.2455 1.7009538873 91.5999154985 84.8910845015
WSB/EiJ both 80.8997222222 1.8481437788 84.5444078199 77.2550366246




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA