Project measure / variable:   CSNA03   damping_cc

ID, description, units MPD:112547   damping_cc   number of days required for circadian rhythm amplitude to decrease to 36% of initial value, in fibroblast cultures, CC   [days]  
Data set, strains CSNA03   CC w/par   40 strains     sex: both     age: 8-12wks
Procedure in vitro assay
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CSNA03 - number of days required for circadian rhythm amplitude to decrease to 36% of initial value, in fibroblast cultures, CC



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested35 strains34 strains
Mean of the strain means1.8512   days 1.3133   days
Median of the strain means1.2687   days 1.2713   days
SD of the strain means± 2.6891 ± 0.25284
Coefficient of variation (CV)1.4526 0.1925
Min–max range of strain means-0.12475   –   16.544   days 0.89803   –   1.8945   days
Mean sample size per strain3.9   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0228 0.0228 0.1491 0.6998
strain 23 14.6845 0.6385 4.1771 < 0.0001
sex:strain 23 5.3697 0.2335 1.5274 0.065
Residuals 197 30.111 0.1528


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.1438 0.25342   10 0.08014 0.2216 0.7805, 1.6383 -0.26
129S1/SvImJ m 1.1634 0.12611   9 0.04204 0.1084 0.95975, 1.3713 -0.59
A/J f 1.624 0.23659   9 0.07886 0.1457 1.2327, 1.9755 -0.08
A/J m 1.6012 0.21734   10 0.06873 0.1357 1.263, 1.9755 1.14
C57BL/6J f 1.4615 0.33909   10 0.10723 0.232 0.686, 1.9333 -0.14
C57BL/6J m 1.5455 0.4605   10 0.14562 0.298 0.8225, 2.3558 0.92
CAST/EiJ f 1.4628 0.32948   10 0.10419 0.2252 1.174, 2.318 -0.14
CAST/EiJ m 1.3716 0.27034   10 0.08549 0.1971 1.1042, 1.905 0.23
CC001/UncJ f 1.3765 0.19163   2   0.1355 0.1392 1.241, 1.512 -0.18
CC001/UncJ m 1.599 0.0   1   0.0 0.0 1.599, 1.599 1.13
CC002/UncJ f 1.0813 0.36098   2   0.25525 0.3339 0.826, 1.3365 -0.29
CC002/UncJ m 1.0673 0.30582   2   0.21625 0.2866 0.851, 1.2835 -0.97
CC003/UncJ f 16.544 0.0   1   0.0 0.0 16.544, 16.544 5.46
CC004/TauUncJ f 1.2547 0.12728   2   0.09 0.1014 1.1647, 1.3447 -0.22
CC004/TauUncJ m 0.96947 0.21811   2   0.15422 0.225 0.81525, 1.1237 -1.36
CC005/TauUncJ f 1.0044 0.30736   4 0.15368 0.306 0.789, 1.4578 -0.31
CC005/TauUncJ m 0.89803 0.12038   3 0.0695 0.134 0.76275, 0.99333 -1.64
CC008/GeniUncJ f 3.0039 2.7093   2   1.9158 0.9019 1.0882, 4.9197 0.43
CC008/GeniUncJ m 1.4573 0.60436   2   0.42735 0.4147 1.03, 1.8847 0.57
CC010/GeniUncJ m 0.95027 0.20921   2   0.14794 0.2202 0.80233, 1.0982 -1.44
CC011/UncJ f 0.94608 0.02581   3 0.0149 0.0273 0.917, 0.96625 -0.34
CC011/UncJ m 1.1211 0.10099   6 0.04123 0.0901 0.96525, 1.2208 -0.76
CC012/GeniUncJ f 0.99048 0.07581   5 0.0339 0.0765 0.86475, 1.07 -0.32
CC012/GeniUncJ m 1.3334 0.32034   6 0.13078 0.2402 1.037, 1.8955 0.08
CC013/GeniUncJ f 1.375 0.47252   3 0.27281 0.3436 1.0925, 1.9205 -0.18
CC013/GeniUncJ m 1.2215 0.3288   2   0.2325 0.2692 0.989, 1.454 -0.36
CC016/GeniUncJ f 1.0975 0.0792   2   0.056 0.0722 1.0415, 1.1535 -0.28
CC016/GeniUncJ m 1.4207 0.08945   2   0.06325 0.063 1.3575, 1.484 0.42
CC017/UncJ m 1.1117 0.08928   3 0.05154 0.0803 1.0395, 1.2115 -0.8
CC018/UncJ f 1.2361 0.01754   2   0.0124 0.0142 1.2237, 1.2485 -0.23
CC018/UncJ m 0.96086 0.15517   3 0.08959 0.1615 0.82933, 1.132 -1.39
CC019/TauUncJ f 1.1797 0.13819   3 0.07978 0.1171 1.0397, 1.316 -0.25
CC019/TauUncJ m 1.1412 0.04632   2   0.03275 0.0406 1.1085, 1.174 -0.68
CC023/GeniUncJ f -0.12475 2.372   2   1.6772 -19.0139 -1.802, 1.5525 -0.73
CC023/GeniUncJ m 1.2063 0.31431   2   0.22225 0.2606 0.984, 1.4285 -0.42
CC025/GeniUncJ f 1.2687 0.30201   5 0.13506 0.238 1.0245, 1.7 -0.22
CC025/GeniUncJ m 1.2205 0.26826   4 0.13413 0.2198 0.86067, 1.5035 -0.37
CC028/GeniUncJ f 1.074 0.14757   3 0.0852 0.1374 0.90375, 1.1655 -0.29
CC028/GeniUncJ m 1.0635 0.18076   3 0.10436 0.17 0.8625, 1.2127 -0.99
CC030/GeniUncJ f 1.5665 0.10394   2   0.0735 0.0664 1.493, 1.64 -0.11
CC030/GeniUncJ m 1.485 0.0   1   0.0 0.0 1.485, 1.485 0.68
CC035/UncJ f 0.81733 0.0   1   0.0 0.0 0.81733, 0.81733 -0.38
CC037/TauUncJ f 1.0945 0.0   1   0.0 0.0 1.0945, 1.0945 -0.28
CC041/TauUncJ f 0.89848 0.11328   4 0.05664 0.1261 0.81867, 1.0665 -0.35
CC041/TauUncJ m 0.95261 0.13724   6 0.05603 0.1441 0.775, 1.0955 -1.43
CC043/GeniUncJ m 1.283 0.0   1   0.0 0.0 1.283, 1.283 -0.12
CC051/TauUncJ f 1.4335 0.0   1   0.0 0.0 1.4335, 1.4335 -0.16
CC051/TauUncJ m 1.8945 0.0   1   0.0 0.0 1.8945, 1.8945 2.3
CC057/UncJ f 5.4023 0.0   1   0.0 0.0 5.4023, 5.4023 1.32
CC059/TauUncJ f 1.095 0.39482   4 0.19741 0.3606 0.72625, 1.595 -0.28
CC061/GeniUncJ f 2.0835 0.0   1   0.0 0.0 2.0835, 2.0835 0.09
CC061/GeniUncJ m 1.6138 0.28744   2   0.20325 0.1781 1.4105, 1.817 1.19
CC068/TauUncJ f 1.278 0.0   1   0.0 0.0 1.278, 1.278 -0.21
CC074/UncJ m 1.2292 0.0   1   0.0 0.0 1.2292, 1.2292 -0.33
CC075/UncJ f 1.8678 0.02369   2   0.01675 0.0127 1.851, 1.8845 0.01
CC075/UncJ m 1.6006 0.36802   3 0.21248 0.2299 1.1832, 1.8785 1.14
CC078/TauUncJ m 1.5745 0.0   1   0.0 0.0 1.5745, 1.5745 1.03
CC080/TauUncJ f 1.561 0.0   1   0.0 0.0 1.561, 1.561 -0.11
CC080/TauUncJ m 1.6875 0.0   1   0.0 0.0 1.6875, 1.6875 1.48
CC084/TauJ f 1.6475 0.04313   2   0.0305 0.0262 1.617, 1.678 -0.08
CC084/TauJ m 1.582 0.38891   2   0.275 0.2458 1.307, 1.857 1.06
NOD/ShiLtJ f 1.2796 0.27777   9 0.09259 0.2171 0.9545, 1.8162 -0.21
NOD/ShiLtJ m 1.2996 0.26411   10 0.08352 0.2032 0.97, 1.8035 -0.05
NZO/HlLtJ f 1.2543 0.29217   8 0.1033 0.2329 0.91625, 1.7663 -0.22
NZO/HlLtJ m 1.2173 0.26122   7 0.09873 0.2146 0.841, 1.565 -0.38
PWK/PhJ f 1.2937 0.42642   10 0.13485 0.3296 0.668, 1.901 -0.21
PWK/PhJ m 1.5507 0.47876   10 0.1514 0.3087 1.0813, 2.72 0.94
WSB/EiJ f 1.2208 0.30266   9 0.10089 0.2479 0.7445, 1.5682 -0.23
WSB/EiJ m 1.2596 0.32666   8 0.11549 0.2593 0.75675, 1.544 -0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.14381 0.1236315721 1.3876212312 0.8999987688
129S1/SvImJ m 1.1633722222 0.1303191195 1.4203718255 0.906372619
A/J f 1.624 0.1303191195 1.8809996033 1.3670003967
A/J m 1.60125 0.1236315721 1.8450612312 1.3574387688
C57BL/6J f 1.4615 0.1236315721 1.7053112312 1.2176887688
C57BL/6J m 1.54551 0.1236315721 1.7893212312 1.3016987688
CAST/EiJ f 1.46279 0.1236315721 1.7066012312 1.2189787688
CAST/EiJ m 1.37161 0.1236315721 1.6154212312 1.1277987688
CC002/UncJ f 1.08125 0.2764485993 1.6264284867 0.5360715133
CC002/UncJ m 1.06725 0.2764485993 1.6124284867 0.5220715133
CC004/TauUncJ f 1.2547 0.2764485993 1.7998784867 0.7095215133
CC004/TauUncJ m 0.969475 0.2764485993 1.5146534867 0.4242965133
CC005/TauUncJ f 1.0043675 0.1954786792 1.3898669049 0.6188680951
CC005/TauUncJ m 0.8980266667 0.2257193362 1.343163037 0.4528902963
CC008/GeniUncJ f 3.00395 0.2764485993 3.5491284867 2.4587715133
CC008/GeniUncJ m 1.45735 0.2764485993 2.0025284867 0.9121715133
CC011/UncJ f 0.9460833333 0.2257193362 1.3912197037 0.500946963
CC011/UncJ m 1.1211416667 0.1596076732 1.4359006127 0.8063827206
CC012/GeniUncJ f 0.99048 0.174841446 1.3352811498 0.6456788502
CC012/GeniUncJ m 1.3333833333 0.1596076732 1.6481422794 1.0186243873
CC013/GeniUncJ f 1.375 0.2257193362 1.8201363704 0.9298636296
CC013/GeniUncJ m 1.2215 0.2764485993 1.7666784867 0.6763215133
CC016/GeniUncJ f 1.0975 0.2764485993 1.6426784867 0.5523215133
CC016/GeniUncJ m 1.42075 0.2764485993 1.9659284867 0.8755715133
CC018/UncJ f 1.2361 0.2764485993 1.7812784867 0.6909215133
CC018/UncJ m 0.96086 0.2257193362 1.4059963704 0.5157236296
CC019/TauUncJ f 1.1796666667 0.2257193362 1.624803037 0.7345302963
CC019/TauUncJ m 1.14125 0.2764485993 1.6864284867 0.5960715133
CC023/GeniUncJ f -0.12475 0.2764485993 0.4204284867 -0.6699284867
CC023/GeniUncJ m 1.20625 0.2764485993 1.7514284867 0.6610715133
CC025/GeniUncJ f 1.26868 0.174841446 1.6134811498 0.9238788502
CC025/GeniUncJ m 1.2205425 0.1954786792 1.6060419049 0.8350430951
CC028/GeniUncJ f 1.0739833333 0.2257193362 1.5191197037 0.628846963
CC028/GeniUncJ m 1.0635 0.2257193362 1.5086363704 0.6183636296
CC041/TauUncJ f 0.89848 0.1954786792 1.2839794049 0.5129805951
CC041/TauUncJ m 0.9526116667 0.1596076732 1.2673706127 0.6378527206
CC075/UncJ f 1.86775 0.2764485993 2.4129284867 1.3225715133
CC075/UncJ m 1.6005666667 0.2257193362 2.045703037 1.1554302963
CC084/TauJ f 1.6475 0.2764485993 2.1926784867 1.1023215133
CC084/TauJ m 1.582 0.2764485993 2.1271784867 1.0368215133
NOD/ShiLtJ f 1.2795777778 0.1303191195 1.536577381 1.0225781745
NOD/ShiLtJ m 1.29958 0.1236315721 1.5433912312 1.0557687688
NZO/HlLtJ f 1.25426875 0.1382242997 1.5268579933 0.9816795067
NZO/HlLtJ m 1.2172571429 0.147767992 1.5086673017 0.925846984
PWK/PhJ f 1.293725 0.1236315721 1.5375362312 1.0499137688
PWK/PhJ m 1.55065 0.1236315721 1.7944612312 1.3068387688
WSB/EiJ f 1.2208188889 0.1303191195 1.4778184921 0.9638192856
WSB/EiJ m 1.25959375 0.1382242997 1.5321829933 0.9870045067


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.1535911111 0.0898162548 1.3307158641 0.9764663581
A/J both 1.612625 0.0898162548 1.789749753 1.435500247
C57BL/6J both 1.503505 0.087420723 1.6759055749 1.3311044251
CAST/EiJ both 1.4172 0.087420723 1.5896005749 1.2447994251
CC002/UncJ both 1.07425 0.1954786792 1.4597494049 0.6887505951
CC004/TauUncJ both 1.1120875 0.1954786792 1.4975869049 0.7265880951
CC005/TauUncJ both 0.9511970833 0.1492993074 1.2456271172 0.6567670495
CC008/GeniUncJ both 2.23065 0.1954786792 2.6161494049 1.8451505951
CC011/UncJ both 1.0336125 0.1382242997 1.3062017433 0.7610232567
CC012/GeniUncJ both 1.1619316667 0.1183682185 1.3953631486 0.9285001847
CC013/GeniUncJ both 1.29825 0.1784468036 1.6501611999 0.9463388001
CC016/GeniUncJ both 1.259125 0.1954786792 1.6446244049 0.8736255951
CC018/UncJ both 1.09848 0.1784468036 1.4503911999 0.7465688001
CC019/TauUncJ both 1.1604583333 0.1784468036 1.5123695333 0.8085471334
CC023/GeniUncJ both 0.54075 0.1954786792 0.9262494049 0.1552505951
CC025/GeniUncJ both 1.24461125 0.1311310845 1.5032121124 0.9860103876
CC028/GeniUncJ both 1.0687416667 0.1596076732 1.3835006127 0.7539827206
CC041/TauUncJ both 0.9255458333 0.1261809449 1.1743846292 0.6767070375
CC075/UncJ both 1.7341583333 0.1784468036 2.0860695333 1.3822471334
CC084/TauJ both 1.61475 0.1954786792 2.0002494049 1.2292505951
NOD/ShiLtJ both 1.2895788889 0.0898162548 1.4667036419 1.1124541359
NZO/HlLtJ both 1.2357629464 0.1011698281 1.4352778433 1.0362480496
PWK/PhJ both 1.4221875 0.087420723 1.5945880749 1.2497869251
WSB/EiJ both 1.2402063194 0.0949855646 1.4275253599 1.052887279




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA