Project measure / variable:   CSNA03   phase_in

ID, description, units MPD:112540   phase_in   specific time point when bioluminescence reaches highest circadian rhythm amplitude (cycle number), in fibroblast cultures, founders   [n]  
Data set, strains CSNA03   inbred w/CC8   8 strains     sex: both     age: 8-12wks
Procedure in vitro assay
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  STRAIN COMPARISON PLOT
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CSNA03 - specific time point when bioluminescence reaches highest circadian rhythm amplitude (cycle number), in fibroblast cultures, founders



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means3.1529   n 3.4864   n
Median of the strain means2.9845   n 3.3824   n
SD of the strain means± 0.77817 ± 0.7578
Coefficient of variation (CV)0.2468 0.2174
Min–max range of strain means1.978   –   4.5035   n 2.0932   –   4.3578   n
Mean sample size per strain9.4   mice 9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4.0129 4.0129 4.0858 0.0453
strain 7 60.7179 8.674 8.8317 < 0.0001
sex:strain 7 18.6024 2.6575 2.7058 0.0119
Residuals 131 128.6601 0.9821


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.7396 0.86203   10 0.2726 0.3147 1.2015, 3.9857 -0.53
129S1/SvImJ m 3.3415 0.65622   9 0.21874 0.1964 2.7477, 4.879 -0.19
A/J f 3.9739 1.4927   9 0.49755 0.3756 0.96967, 5.7873 1.05
A/J m 4.3578 1.3637   9 0.45458 0.3129 2.1573, 6.211 1.15
C57BL/6J f 4.5035 0.94989   10 0.30038 0.2109 3.3537, 6.4568 1.74
C57BL/6J m 3.4233 0.69286   10 0.2191 0.2024 2.5543, 4.4967 -0.08
CAST/EiJ f 1.978 0.90551   10 0.28635 0.4578 0.84725, 3.4713 -1.51
CAST/EiJ m 2.0932 0.83365   10 0.26362 0.3983 0.58775, 3.5928 -1.84
NOD/ShiLtJ f 3.2399 1.0086   9 0.33619 0.3113 2.178, 4.787 0.11
NOD/ShiLtJ m 3.2767 0.86524   9 0.28841 0.2641 1.3388, 4.36 -0.28
NZO/HlLtJ f 2.8196 1.0878   8 0.3846 0.3858 0.78933, 3.886 -0.43
NZO/HlLtJ m 3.0046 1.2124   7 0.45825 0.4035 1.1, 4.1555 -0.64
PWK/PhJ f 2.9007 0.47471   10 0.15012 0.1637 1.9387, 3.524 -0.32
PWK/PhJ m 4.2627 1.2099   10 0.3826 0.2838 2.3375, 5.7205 1.02
WSB/EiJ f 3.0683 1.026   9 0.34201 0.3344 1.4805, 4.7633 -0.11
WSB/EiJ m 4.1312 0.83626   8 0.29566 0.2024 3.0187, 5.1455 0.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.73964 0.3133908223 3.3596018025 2.1196781975
129S1/SvImJ m 3.3415 0.3303429321 3.9949971194 2.6880028806
A/J f 3.9738522222 0.3303429321 4.6273493416 3.3203551029
A/J m 4.3577666667 0.3303429321 5.011263786 3.7042695473
C57BL/6J f 4.50349 0.3133908223 5.1234518025 3.8835281975
C57BL/6J m 3.42326 0.3133908223 4.0432218025 2.8032981975
CAST/EiJ f 1.978005 0.3133908223 2.5979668025 1.3580431975
CAST/EiJ m 2.093185 0.3133908223 2.7131468025 1.4732231975
NOD/ShiLtJ f 3.2398888889 0.3303429321 3.8933860083 2.5863917695
NOD/ShiLtJ m 3.2767111111 0.3303429321 3.9302082305 2.6232139917
NZO/HlLtJ f 2.81955375 0.3503815911 3.5126921169 2.1264153831
NZO/HlLtJ m 3.0046 0.3745736767 3.745596083 2.263603917
PWK/PhJ f 2.90068 0.3133908223 3.5206418025 2.2807181975
PWK/PhJ m 4.26271 0.3133908223 4.8826718025 3.6427481975
WSB/EiJ f 3.0683222222 0.3303429321 3.7218193416 2.4148251029
WSB/EiJ m 4.13125 0.3503815911 4.8243883669 3.4381116331


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.04057 0.227673154 3.4909618076 2.5901781924
A/J both 4.1658094444 0.2335877274 4.627901689 3.7037171999
C57BL/6J both 3.963375 0.2216007756 4.4017541946 3.5249958054
CAST/EiJ both 2.035595 0.2216007756 2.4739741946 1.5972158054
NOD/ShiLtJ both 3.2583 0.2335877274 3.7203922446 2.7962077554
NZO/HlLtJ both 2.912076875 0.2564530652 3.4194022121 2.4047515379
PWK/PhJ both 3.581695 0.2216007756 4.0200741946 3.1433158054
WSB/EiJ both 3.5997861111 0.2407767182 4.0760998944 3.1234723278




  GWAS USING LINEAR MIXED MODELS