Project measure / variable:   CSNA03   period_in

ID, description, units MPD:112539   period_in   peak-to-peak interval, indicating amount of time it takes for one cycle of bioluminescence circadian rhythm, in fibroblast cultures, founders   [h]  
Data set, strains CSNA03   inbred w/CC8   8 strains     sex: both     age: 8-12wks
Procedure in vitro assay
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  STRAIN COMPARISON PLOT
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CSNA03 - peak-to-peak interval, indicating amount of time it takes for one cycle of bioluminescence circadian rhythm, in fibroblast cultures, founders



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means23.713   h 23.845   h
Median of the strain means23.803   h 23.765   h
SD of the strain means± 0.40585 ± 0.46886
Coefficient of variation (CV)0.0171 0.0197
Min–max range of strain means23.051   –   24.32   h 23.117   –   24.616   h
Mean sample size per strain9.4   mice 9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.7081 0.7081 5.9089 0.0164
strain 7 22.7796 3.2542 27.1571 < 0.0001
sex:strain 7 2.8071 0.401 3.3465 0.0026
Residuals 131 15.6977 0.1198


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.43 0.33438   10 0.10574 0.0143 22.682, 23.909 -0.7
129S1/SvImJ m 23.754 0.27001   9 0.09 0.0114 23.291, 24.084 -0.19
A/J f 24.32 0.52835   9 0.17612 0.0217 23.803, 25.627 1.5
A/J m 24.616 0.50671   9 0.1689 0.0206 24.042, 25.494 1.64
C57BL/6J f 24.07 0.26043   10 0.08236 0.0108 23.677, 24.478 0.88
C57BL/6J m 23.608 0.35552   10 0.11243 0.0151 22.942, 24.003 -0.51
CAST/EiJ f 23.051 0.3744   10 0.11839 0.0162 22.263, 23.546 -1.63
CAST/EiJ m 23.117 0.2725   10 0.08617 0.0118 22.722, 23.695 -1.55
NOD/ShiLtJ f 23.804 0.30918   9 0.10306 0.013 23.422, 24.393 0.22
NOD/ShiLtJ m 24.036 0.33884   9 0.11295 0.0141 23.636, 24.729 0.41
NZO/HlLtJ f 23.803 0.14394   8 0.05089 0.006 23.593, 24.096 0.22
NZO/HlLtJ m 23.776 0.30258   7 0.11436 0.0127 23.377, 24.297 -0.15
PWK/PhJ f 23.84 0.20191   10 0.06385 0.0085 23.628, 24.284 0.31
PWK/PhJ m 24.312 0.40052   10 0.12665 0.0165 23.82, 25.044 1.0
WSB/EiJ f 23.387 0.41155   9 0.13718 0.0176 22.647, 23.863 -0.8
WSB/EiJ m 23.544 0.29271   8 0.10349 0.0124 22.967, 23.962 -0.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.43 0.1094666764 23.6465511981 23.2134488019
129S1/SvImJ m 23.7537777778 0.1153880085 23.9820427831 23.5255127725
A/J f 24.3196666667 0.1153880085 24.547931672 24.0914016614
A/J m 24.6158888889 0.1153880085 24.8441538942 24.3876238836
C57BL/6J f 24.0704 0.1094666764 24.2869511981 23.8538488019
C57BL/6J m 23.6076 0.1094666764 23.8241511981 23.3910488019
CAST/EiJ f 23.0508 0.1094666764 23.2673511981 22.8342488019
CAST/EiJ m 23.1167 0.1094666764 23.3332511981 22.9001488019
NOD/ShiLtJ f 23.8035555556 0.1153880085 24.0318205609 23.5752905502
NOD/ShiLtJ m 24.0357777778 0.1153880085 24.2640427831 23.8075127725
NZO/HlLtJ f 23.802625 0.1223874649 24.0447365997 23.5605134003
NZO/HlLtJ m 23.7761428571 0.1308377034 24.0349710445 23.5173146698
PWK/PhJ f 23.8401 0.1094666764 24.0566511981 23.6235488019
PWK/PhJ m 24.3124 0.1094666764 24.5289511981 24.0958488019
WSB/EiJ f 23.387 0.1153880085 23.6152650053 23.1587349947
WSB/EiJ m 23.5445 0.1223874649 23.7866115997 23.3023884003


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 23.5918888889 0.0795256967 23.749209687 23.4345680908
A/J both 24.4677777778 0.0815916433 24.6291855109 24.3063700446
C57BL/6J both 23.839 0.0774046292 23.9921248206 23.6858751794
CAST/EiJ both 23.08375 0.0774046292 23.2368748206 22.9306251794
NOD/ShiLtJ both 23.9196666667 0.0815916433 24.0810743998 23.7582589335
NZO/HlLtJ both 23.7893839286 0.0895784519 23.9665914745 23.6121763827
PWK/PhJ both 24.07625 0.0774046292 24.2293748206 23.9231251794
WSB/EiJ both 23.46575 0.0841027408 23.6321252832 23.2993747168




  GWAS USING LINEAR MIXED MODELS