MPD: Project measure / variable: Zimmermann1 water_intake

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Visualization Options Least squares means Alphabetical order Strains on X-axis Individual points

Zimmermann1 - water consumption, second day during dark

Measure Summary	Female	Male
Number of strains tested	30 strains	30 strains
Mean of the strain means	2.9266 mL	3.0318 mL
Median of the strain means	2.8141 mL	3.1254 mL
SD of the strain means	± 1.0771	± 1.2272
Coefficient of variation (CV)	0.368	0.4048
Min–max range of strain means	1.2989 – 6.3942 mL	0.49333 – 6.632 mL
Mean sample size per strain	11.2 mice	11.1 mice

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p value (Pr>F)
sex	1	2.0734	2.0734	1.4737	0.2252
strain	29	775.0097	26.7245	18.9943	< 0.0001
sex:strain	29	62.5515	2.1569	1.533	0.0379
Residuals	611	859.6623	1.407

Q-Q normality assessment based on residuals

STRAIN MEANS (UNADJUSTED)

Strain	Sex	Mean	SD	N mice	SEM	CV	Min, Max	Z score
129S1/SvImJ	f	3.0533	1.1403	12	0.32919	0.3735	1.34, 5.2	0.12
129S1/SvImJ	m	3.454	0.92682	10	0.29309	0.2683	1.55, 4.71	0.34
129X1/SvJ	f	2.835	0.91548	6	0.37374	0.3229	2.04, 4.25	-0.09
129X1/SvJ	m	3.4325	0.79796	8	0.28212	0.2325	1.73, 3.96	0.33
A/J	f	2.2383	1.7265	12	0.49839	0.7713	0.01, 5.41	-0.64
A/J	m	2.705	1.2732	12	0.36755	0.4707	0.4, 4.4	-0.27
AKR/J	f	3.0667	1.1682	12	0.33723	0.3809	0.12, 4.51	0.13
AKR/J	m	3.5682	0.79299	11	0.2391	0.2222	2.38, 5.34	0.44
BALB/cJ	f	2.0618	0.75637	11	0.22805	0.3668	0.09, 2.96	-0.8
BALB/cJ	m	2.5427	0.88202	11	0.26594	0.3469	0.61, 3.64	-0.4
BTBR T⁺ Itpr3^tf/J	f	4.96	0.86262	12	0.24902	0.1739	3.35, 5.96	1.89
BTBR T⁺ Itpr3^tf/J	m	5.135	0.81201	12	0.23441	0.1581	4.22, 7.23	1.71
BUB/BnJ	f	4.0064	0.3754	11	0.11319	0.0937	3.13, 4.65	1.0
BUB/BnJ	m	3.9191	0.65907	11	0.19872	0.1682	3.26, 5.61	0.72
C3H/HeJ	f	1.8158	1.1991	12	0.34615	0.6604		-1.03
C3H/HeJ	m	1.5692	1.3648	12	0.39397	0.8697		-1.19
C3H/HeOuJ	f	2.34	1.1828	12	0.34146	0.5055		-0.54
C3H/HeOuJ	m	3.9133	1.3855	12	0.39996	0.354	1.58, 7.56	0.72
C57BL/6J	f	3.1742	0.61729	12	0.1782	0.1945	2.23, 4.72	0.23
C57BL/6J	m	3.3783	0.72514	12	0.20933	0.2146	2.38, 5.06	0.28
C57BL/6NCrl	f	2.7933	1.0896	12	0.31453	0.3901	0.1, 4.35	-0.12
C57BL/6NCrl	m	3.0733	0.7096	12	0.20484	0.2309	2.18, 4.63	0.03
C57BL/6NJ	f	2.8183	0.97726	12	0.28211	0.3468	0.05, 3.9	-0.1
C57BL/6NJ	m	3.4467	0.82706	12	0.23875	0.24	1.2, 4.66	0.34
CBA/J	f	2.81	1.4027	12	0.40493	0.4992	0.05, 4.14	-0.11
CBA/J	m	3.0233	1.7725	12	0.51166	0.5863		-0.01
DBA/1J	f	2.6764	1.4764	11	0.44514	0.5516	0.04, 4.38	-0.23
DBA/1J	m	2.86	1.3957	12	0.40291	0.488	0.06, 4.35	-0.14
DBA/2J	f	2.6425	1.292	12	0.37296	0.4889		-0.26
DBA/2J	m	3.3591	1.3812	11	0.41644	0.4112		0.27
FVB/NJ	f	1.4542	0.9622	12	0.27776	0.6617		-1.37
FVB/NJ	m	1.4767	0.90554	12	0.26141	0.6132		-1.27
KK/HlJ	f	3.9942	1.3237	12	0.38211	0.3314	0.17, 5.0	0.99
KK/HlJ	m	3.5	0.76104	12	0.21969	0.2174	2.37, 4.78	0.38
LG/J	f	3.94	1.0182	12	0.29392	0.2584	1.39, 5.12	0.94
LG/J	m	3.1775	1.6686	12	0.48169	0.5251	0.88, 6.03	0.12
LP/J	f	1.886	0.79289	10	0.25073	0.4204	0.11, 3.07	-0.97
LP/J	m	2.0227	1.2888	11	0.38859	0.6372		-0.82
MA/MyJ	f	3.442	1.3446	10	0.42519	0.3906	0.16, 4.72	0.48
MA/MyJ	m	1.9744	1.6664	9	0.55548	0.844	0.05, 4.32	-0.86
MRL/MpJ	f	3.3317	0.7155	12	0.20655	0.2148	1.61, 4.17	0.38
MRL/MpJ	m	4.5133	1.8363	12	0.53008	0.4069	0.09, 6.86	1.21
NOD/ShiLtJ	f	2.9558	1.7999	12	0.5196	0.6089	0.01, 5.58	0.03
NOD/ShiLtJ	m	2.6892	2.0809	12	0.60072	0.7738		-0.28
NON/ShiLtJ	f	3.604	0.69682	10	0.22035	0.1933	2.46, 4.85	0.63
NON/ShiLtJ	m	3.8308	0.63292	12	0.18271	0.1652	2.69, 4.81	0.65
NZB/BlNJ	f	2.0725	1.7062	12	0.49253	0.8232		-0.79
NZB/BlNJ	m	2.9825	1.3803	12	0.39845	0.4628		-0.04
NZO/HlLtJ	f	6.3942	1.2095	12	0.34914	0.1892	4.24, 8.34	3.22
NZO/HlLtJ	m	6.632	1.5162	10	0.47945	0.2286	4.04, 9.8	2.93
NZW/LacJ	f	3.8308	0.48991	12	0.14142	0.1279	2.72, 4.42	0.84
NZW/LacJ	m	3.3727	0.67409	11	0.20325	0.1999	2.72, 5.02	0.28
RIIIS/J	f	1.5518	0.49122	11	0.14811	0.3165	0.75, 2.52	-1.28
RIIIS/J	m	1.0322	0.47352	9	0.15784	0.4587	0.39, 1.97	-1.63
SJL/J	f	2.7091	0.98241	11	0.29621	0.3626	0.3, 4.0	-0.2
SJL/J	m	2.4325	1.1984	12	0.34596	0.4927		-0.49
SM/J	f	2.04	1.5624	9	0.5208	0.7659		-0.82
SM/J	m	1.4456	1.0745	9	0.35815	0.7433	0.01, 2.61	-1.29
SWR/J	f	1.2989	1.6386	9	0.54621	1.2616	0.08, 3.93	-1.51
SWR/J	m	0.49333	0.92481	9	0.30827	1.8746		-2.07

LEAST SQUARES MEANS (MODEL-ADJUSTED)

Strain	Sex	Mean	SEM	UpperCL	LowerCL
129S1/SvImJ	f	3.0533333333	0.3424149387	3.7257863353	2.3808803313
129S1/SvImJ	m	3.454	0.3750967719	4.1906353561	2.7173646439
129X1/SvJ	f	2.835	0.4842478503	3.7859921555	1.8840078445
129X1/SvJ	m	3.4325	0.4193709401	4.2560833655	2.6089166345
A/J	f	2.2383333333	0.3424149387	2.9107863353	1.5658803313
A/J	m	2.705	0.3424149387	3.377453002	2.032546998
AKR/J	f	3.0666666667	0.3424149387	3.7391196687	2.3942136647
AKR/J	m	3.5681818182	0.3576407394	4.2705360722	2.8658275642
BALB/cJ	f	2.0618181818	0.3576407394	2.7641724358	1.3594639278
BALB/cJ	m	2.5427272727	0.3576407394	3.2450815267	1.8403730187
BTBR T⁺ Itpr3^tf/J	f	4.96	0.3424149387	5.632453002	4.287546998
BTBR T⁺ Itpr3^tf/J	m	5.135	0.3424149387	5.807453002	4.462546998
BUB/BnJ	f	4.0063636364	0.3576407394	4.7087178904	3.3040093824
BUB/BnJ	m	3.9190909091	0.3576407394	4.6214451631	3.2167366551
C3H/HeJ	f	1.8158333333	0.3424149387	2.4882863353	1.1433803313
C3H/HeJ	m	1.5691666667	0.3424149387	2.2416196687	0.8967136647
C3H/HeOuJ	f	2.34	0.3424149387	3.012453002	1.667546998
C3H/HeOuJ	m	3.9133333333	0.3424149387	4.5857863353	3.2408803313
C57BL/6J	f	3.1741666667	0.3424149387	3.8466196687	2.5017136647
C57BL/6J	m	3.3783333333	0.3424149387	4.0507863353	2.7058803313
C57BL/6NCrl	f	2.7933333333	0.3424149387	3.4657863353	2.1208803313
C57BL/6NCrl	m	3.0733333333	0.3424149387	3.7457863353	2.4008803313
C57BL/6NJ	f	2.8183333333	0.3424149387	3.4907863353	2.1458803313
C57BL/6NJ	m	3.4466666667	0.3424149387	4.1191196687	2.7742136647
CBA/J	f	2.81	0.3424149387	3.482453002	2.137546998
CBA/J	m	3.0233333333	0.3424149387	3.6957863353	2.3508803313
DBA/1J	f	2.6763636364	0.3576407394	3.3787178904	1.9740093824
DBA/1J	m	2.86	0.3424149387	3.532453002	2.187546998
DBA/2J	f	2.6425	0.3424149387	3.314953002	1.970046998
DBA/2J	m	3.3590909091	0.3576407394	4.0614451631	2.6567366551
FVB/NJ	f	1.4541666667	0.3424149387	2.1266196687	0.7817136647
FVB/NJ	m	1.4766666667	0.3424149387	2.1491196687	0.8042136647
KK/HlJ	f	3.9941666667	0.3424149387	4.6666196687	3.3217136647
KK/HlJ	m	3.5	0.3424149387	4.172453002	2.827546998
LG/J	f	3.94	0.3424149387	4.612453002	3.267546998
LG/J	m	3.1775	0.3424149387	3.849953002	2.505046998
LP/J	f	1.886	0.3750967719	2.6226353561	1.1493646439
LP/J	m	2.0227272727	0.3576407394	2.7250815267	1.3203730187
MA/MyJ	f	3.442	0.3750967719	4.1786353561	2.7053646439
MA/MyJ	m	1.9744444444	0.3953867141	2.7509262879	1.197962601
MRL/MpJ	f	3.3316666667	0.3424149387	4.0041196687	2.6592136647
MRL/MpJ	m	4.5133333333	0.3424149387	5.1857863353	3.8408803313
NOD/ShiLtJ	f	2.9558333333	0.3424149387	3.6282863353	2.2833803313
NOD/ShiLtJ	m	2.6891666667	0.3424149387	3.3616196687	2.0167136647
NON/ShiLtJ	f	3.604	0.3750967719	4.3406353561	2.8673646439
NON/ShiLtJ	m	3.8308333333	0.3424149387	4.5032863353	3.1583803313
NZB/BlNJ	f	2.0725	0.3424149387	2.744953002	1.400046998
NZB/BlNJ	m	2.9825	0.3424149387	3.654953002	2.310046998
NZO/HlLtJ	f	6.3941666667	0.3424149387	7.0666196687	5.7217136647
NZO/HlLtJ	m	6.632	0.3750967719	7.3686353561	5.8953646439
NZW/LacJ	f	3.8308333333	0.3424149387	4.5032863353	3.1583803313
NZW/LacJ	m	3.3727272727	0.3576407394	4.0750815267	2.6703730187
RIIIS/J	f	1.5518181818	0.3576407394	2.2541724358	0.8494639278
RIIIS/J	m	1.0322222222	0.3953867141	1.8087040657	0.2557403788
SJL/J	f	2.7090909091	0.3576407394	3.4114451631	2.0067366551
SJL/J	m	2.4325	0.3424149387	3.104953002	1.760046998
SM/J	f	2.04	0.3953867141	2.8164818435	1.2635181565
SM/J	m	1.4455555556	0.3953867141	2.222037399	0.6690737121
SWR/J	f	1.2988888889	0.3953867141	2.0753707324	0.5224070454
SWR/J	m	0.4933333333	0.3953867141	1.2698151768	-0.2831485101

LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED

Strain	Sex	Mean	SEM	UpperCL	LowerCL
129S1/SvImJ	both	3.2536666667	0.253941715	3.7523711603	2.754962173
129X1/SvJ	both	3.13375	0.3202998462	3.7627721856	2.5047278144
A/J	both	2.4716666667	0.2421239251	2.9471627444	1.9961705889
AKR/J	both	3.3174242424	0.2475655917	3.8036069596	2.8312415252
BALB/cJ	both	2.3022727273	0.252890192	2.7989121831	1.8056332715
BTBR T⁺ Itpr3^tf/J	both	5.0475	0.2421239251	5.5229960778	4.5720039222
BUB/BnJ	both	3.9627272727	0.252890192	4.4593667285	3.4660878169
C3H/HeJ	both	1.6925	0.2421239251	2.1679960778	1.2170039222
C3H/HeOuJ	both	3.1266666667	0.2421239251	3.6021627444	2.6511705889
C57BL/6J	both	3.27625	0.2421239251	3.7517460778	2.8007539222
C57BL/6NCrl	both	2.9333333333	0.2421239251	3.4088294111	2.4578372556
C57BL/6NJ	both	3.1325	0.2421239251	3.6079960778	2.6570039222
CBA/J	both	2.9166666667	0.2421239251	3.3921627444	2.4411705889
DBA/1J	both	2.7681818182	0.2475655917	3.2543645354	2.281999101
DBA/2J	both	3.0007954545	0.2475655917	3.4869781717	2.5146127373
FVB/NJ	both	1.4654166667	0.2421239251	1.9409127444	0.9899205889
KK/HlJ	both	3.7470833333	0.2421239251	4.2225794111	3.2715872556
LG/J	both	3.55875	0.2421239251	4.0342460778	3.0832539222
LP/J	both	1.9543636364	0.2591353347	2.4632676416	1.4454596312
MA/MyJ	both	2.7082222222	0.2725014871	3.2433754015	2.173069043
MRL/MpJ	both	3.9225	0.2421239251	4.3979960778	3.4470039222
NOD/ShiLtJ	both	2.8225	0.2421239251	3.2979960778	2.3470039222
NON/ShiLtJ	both	3.7174166667	0.253941715	4.2161211603	3.218712173
NZB/BlNJ	both	2.5275	0.2421239251	3.0029960778	2.0520039222
NZO/HlLtJ	both	6.5130833333	0.253941715	7.011787827	6.0143788397
NZW/LacJ	both	3.601780303	0.2475655917	4.0879630202	3.1155975858
RIIIS/J	both	1.292020202	0.2665696682	1.8155241541	0.76851625
SJL/J	both	2.5707954545	0.2475655917	3.0569781717	2.0846127373
SM/J	both	1.7427777778	0.2795806267	2.2918333548	1.1937222008
SWR/J	both	0.8961111111	0.2795806267	1.4451666881	0.3470555341

INDIVIDUAL ANIMAL VALUES

Click here to view individual animal values

GWAS USING LINEAR MIXED MODELS

ID, description, units	MPD:112171 water_intake_dark water consumption, second day [mL] during dark
Data set, strains	Zimmermann1 inbred 30 strains sex: both age: 7-15wks
Procedure	intake monitoring
Ontology mappings	MP:0011947 abnormal fluid intake VT:0001422 drinking behavior trait VT:0002121 metabolism trait