Project measure / variable:   Auwerx1   tnf_alpha_HFD

ID, description, units MPD:111393   tnf_alpha_HFD   blood tumor necrosis factor alpha (TNF alpha) amount   [pg/mL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   32 strains     sex: m     age: 29wks
Procedure cell signaling molecule detection
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx1 - blood tumor necrosis factor alpha (TNF alpha) amount HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested32 strains
Mean of the strain means74.92   pg/mL
Median of the strain means70.58   pg/mL
SD of the strain means± 16.589
Coefficient of variation (CV)0.2214
Min–max range of strain means43.748   –   116.4   pg/mL
Mean sample size per strain3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 31 34527.6945 1113.7966 1.9329 0.0085
Residuals 91 52437.5155 576.2364


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD100 m 65.2 28.247   4 14.124 0.4332 34.4, 101.1 -0.59
BXD43 m 70.6 26.431   3 15.26 0.3744 47.13, 99.23 -0.26
BXD44 m 67.5 12.077   2   8.54 0.1789 58.96, 76.04 -0.45
BXD45 m 68.19 15.527   4 7.7634 0.2277 45.77, 80.82 -0.41
BXD48 m 62.98 13.505   5 6.0397 0.2144 42.51, 76.05 -0.72
BXD48a m 78.53 3.5072   2   2.48 0.0447 76.05, 81.01 0.22
BXD51 m 58.59 6.1878   4 3.0939 0.1056 50.58, 65.44 -0.98
BXD55 m 70.82 33.704   4 16.852 0.4759 34.4, 112.6 -0.25
BXD56 m 78.36 18.272   2   12.92 0.2332 65.44, 91.28 0.21
BXD61 m 61.8 31.917   5 14.274 0.5164 34.4, 111.2 -0.79
BXD62 m 79.52 28.436   4 14.218 0.3576 47.12, 111.2 0.28
BXD65 m 78.56 9.5169   4 4.7584 0.1211 71.12, 91.01 0.22
BXD66 m 78.7 20.005   4 10.003 0.2542 61.38, 96.03 0.23
BXD68 m 43.748 12.34   4 6.1699 0.2821 34.4, 60.42 -1.88
BXD69 m 69.97 11.539   4 5.7695 0.1649 60.42, 86.04 -0.3
BXD70 m 58.85 10.394   3 6.001 0.1766 50.58, 70.52 -0.97
BXD71 m 63.94 15.424   3 8.9052 0.2412 50.58, 80.82 -0.66
BXD73 m 70.05 14.02   4 7.01 0.2002 50.58, 83.43 -0.29
BXD73a m 104.7 22.945   5 10.261 0.2191 86.0, 141.8 1.8
BXD73b m 92.06 23.026   5 10.298 0.2501 65.44, 123.4 1.03
BXD75 m 58.52 8.7758   5 3.9246 0.15 45.77, 65.44 -0.99
BXD81 m 60.85 22.97   3 13.262 0.3775 41.06, 86.04 -0.85
BXD83 m 61.71 20.712   3 11.958 0.3356 37.96, 76.04 -0.8
BXD84 m 70.56 8.7988   3 5.08 0.1247 60.4, 75.64 -0.26
BXD85 m 103.8 64.33   3 37.139 0.6195 65.44, 178.1 1.74
BXD87 m 87.29 11.111   4 5.5553 0.1273 76.05, 101.1 0.75
BXD89 m 101.6 50.85   4 25.425 0.5007 50.58, 158.9 1.61
BXD90 m 98.67 20.231   4 10.116 0.205 73.58, 116.3 1.43
BXD98 m 73.22 34.363   5 15.368 0.4693 55.48, 134.2 -0.1
BXD99 m 57.13 11.742   5 5.2511 0.2055 36.46, 65.44 -1.07
C57BL/6J m 85.07 13.34   5 5.9659 0.1568 66.23, 96.03 0.61
DBA/2J m 116.4 30.811   4 15.405 0.2646 86.0, 157.2 2.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD100 m 65.2025 12.0024626064 89.043917518 41.361082482
BXD43 m 70.6 13.8592500334 98.1296976438 43.0703023562
BXD44 m 67.5 16.9740453998 101.2168560002 33.7831439998
BXD45 m 68.19 12.0024626064 92.031417518 44.348582482
BXD48 m 62.984 10.7353289141 84.3084121001 41.6595878999
BXD48a m 78.53 16.9740453998 112.2468560002 44.8131439998
BXD51 m 58.5925 12.0024626064 82.433917518 34.751082482
BXD55 m 70.82 12.0024626064 94.661417518 46.978582482
BXD56 m 78.36 16.9740453998 112.0768560002 44.6431439998
BXD61 m 61.802 10.7353289141 83.1264121001 40.4775878999
BXD62 m 79.52 12.0024626064 103.361417518 55.678582482
BXD65 m 78.565 12.0024626064 102.406417518 54.723582482
BXD66 m 78.705 12.0024626064 102.546417518 54.863582482
BXD68 m 43.7475 12.0024626064 67.588917518 19.906082482
BXD69 m 69.975 12.0024626064 93.816417518 46.133582482
BXD70 m 58.8533333333 13.8592500334 86.3830309771 31.3236356895
BXD71 m 63.94 13.8592500334 91.4696976438 36.4103023562
BXD73 m 70.045 12.0024626064 93.886417518 46.203582482
BXD73a m 104.706 10.7353289141 126.0304121001 83.3815878999
BXD73b m 92.058 10.7353289141 113.3824121001 70.7335878999
BXD75 m 58.516 10.7353289141 79.8404121001 37.1915878999
BXD81 m 60.8533333333 13.8592500334 88.3830309771 33.3236356895
BXD83 m 61.7066666667 13.8592500334 89.2363643105 34.1769690229
BXD84 m 70.56 13.8592500334 98.0896976438 43.0303023562
BXD85 m 103.8366666667 13.8592500334 131.3663643105 76.3069690229
BXD87 m 87.2925 12.0024626064 111.133917518 63.451082482
BXD89 m 101.5625 12.0024626064 125.403917518 77.721082482
BXD90 m 98.6725 12.0024626064 122.513917518 74.831082482
BXD98 m 73.216 10.7353289141 94.5404121001 51.8915878999
BXD99 m 57.132 10.7353289141 78.4564121001 35.8075878999
C57BL/6J m 85.07 10.7353289141 106.3944121001 63.7455878999
DBA/2J m 116.425 12.0024626064 140.266417518 92.583582482




  GWAS USING LINEAR MIXED MODELS