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Project measure / variable:   Auwerx1   ldh_HFD

ID, description, units MPD:111365   ldh_HFD   blood lactate dehydrogenase (LDH) amount   [U/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   52 strains     sex: m     age: 29wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx1 - blood lactate dehydrogenase (LDH) amount HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested52 strains
Mean of the strain means489.2   U/L
Median of the strain means389.2   U/L
SD of the strain means± 396.0
Coefficient of variation (CV)0.8096
Min–max range of strain means71.6   –   2109.0   U/L
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 51 35281610.3258 691796.2809 6.9967 < 0.0001
Residuals 168 16610880.6333 98874.2895


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 188.0 36.626   5 16.38 0.1948 132.0, 227.0 -0.76
BXD100 m 200.8 106.8   5 47.78 0.5321 109.0, 369.0 -0.73
BXD101 m 479.5 221.2   4 110.6 0.4612 208.0, 745.0 -0.02
BXD16 m 442.0 293.8   5 131.4 0.6648 191.0, 937.0 -0.12
BXD27 m 514.0 219.3   4 109.6 0.4266 290.0, 794.0 0.06
BXD32 m 224.7 90.15   3 52.05 0.4012 157.0, 327.0 -0.67
BXD34 m 279.8 56.99   5 25.486 0.2037 193.0, 336.0 -0.53
BXD39 m 1951.0 1072.0   5 479.3 0.5494 914.0, 3500.0 3.69
BXD40 m 183.5 71.95   4 35.976 0.3921 134.0, 288.0 -0.77
BXD43 m 214.3 46.929   3 27.094 0.219 181.0, 268.0 -0.69
BXD44 m 672.4 295.8   5 132.3 0.4399 332.0, 1050.0 0.46
BXD45 m 296.0 281.0   4 140.5 0.9493 75.0, 676.0 -0.49
BXD48 m 280.2 78.62   5 35.159 0.2806 143.0, 335.0 -0.53
BXD48a m 396.7 148.5   3 85.76 0.3745 256.0, 552.0 -0.23
BXD49 m 303.8 83.66   4 41.83 0.2754 246.0, 428.0 -0.47
BXD50 m 270.2 88.26   5 39.472 0.3267 194.0, 408.0 -0.55
BXD51 m 338.0 88.26   4 44.13 0.2611 257.0, 450.0 -0.38
BXD53 m 929.4 673.6   5 301.3 0.7248 418.0, 2087.0 1.11
BXD55 m 144.0 90.21   4 45.105 0.6265 32.0, 234.0 -0.87
BXD56 m 406.5 136.5   2   96.5 0.3357 310.0, 503.0 -0.21
BXD6 m 293.6 66.34   5 29.667 0.2259 223.0, 354.0 -0.49
BXD60 m 2109.0 441.0   4 220.5 0.2091 1662.0, 2715.0 4.09
BXD61 m 464.8 313.4   5 140.2 0.6743 252.0, 1017.0 -0.06
BXD62 m 891.0 633.3   4 316.6 0.7108 211.0, 1678.0 1.01
BXD63 m 1032.0 1152.0   2   814.5 1.1156 218.0, 1847.0 1.37
BXD64 m 539.0 269.0   4 134.5 0.4991 304.0, 837.0 0.13
BXD65 m 707.0 128.4   4 64.21 0.1816 556.0, 870.0 0.55
BXD65a m 398.0 113.9   4 56.93 0.2861 229.0, 471.0 -0.23
BXD66 m 235.0 34.679   4 17.34 0.1476 193.0, 273.0 -0.64
BXD67 m 798.2 682.0   5 305.0 0.8544 254.0, 1931.0 0.78
BXD68 m 281.8 45.441   4 22.721 0.1613 241.0, 330.0 -0.52
BXD69 m 503.6 110.7   5 49.518 0.2199 317.0, 614.0 0.04
BXD70 m 400.0 172.9   3 99.81 0.4322 202.0, 521.0 -0.23
BXD71 m 445.0 108.4   3 62.6 0.2437 321.0, 522.0 -0.11
BXD73 m 237.8 125.9   4 62.95 0.5295 105.0, 384.0 -0.63
BXD73a m 330.8 281.0   5 125.7 0.8495 137.0, 797.0 -0.4
BXD73b m 386.4 102.6   5 45.867 0.2654 256.0, 492.0 -0.26
BXD75 m 216.4 172.9   5 77.32 0.799 32.0, 451.0 -0.69
BXD77 m 295.6 113.3   5 50.67 0.3833 177.0, 460.0 -0.49
BXD79 m 426.2 141.7   5 63.38 0.3325 250.0, 558.0 -0.16
BXD81 m 614.3 244.0   3 140.9 0.3973 356.0, 841.0 0.32
BXD83 m 535.2 384.1   4 192.0 0.7176 249.0, 1088.0 0.12
BXD84 m 330.7 122.5   3 70.7 0.3703 195.0, 433.0 -0.4
BXD85 m 688.8 174.6   4 87.28 0.2534 557.0, 946.0 0.5
BXD87 m 392.0 291.0   5 130.2 0.7424 20.0, 694.0 -0.25
BXD89 m 480.2 428.8   4 214.4 0.8929 242.0, 1123.0 -0.02
BXD90 m 355.5 157.0   4 78.5 0.4416 173.0, 506.0 -0.34
BXD95 m 370.0 108.3   4 54.17 0.2928 282.0, 509.0 -0.3
BXD98 m 1392.0 313.2   5 140.1 0.225 835.0, 1575.0 2.28
BXD99 m 354.4 125.1   5 55.95 0.353 233.0, 556.0 -0.34
C57BL/6J m 146.8 120.7   5 53.97 0.8221 41.0, 331.0 -0.86
DBA/2J m 71.6 38.358   5 17.154 0.5357 9.0, 106.0 -1.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 188.0 140.6231058426 465.6160530871 -89.6160530871
BXD100 m 200.8 140.6231058426 478.4160530871 -76.8160530871
BXD101 m 479.5 157.2214119356 789.884183174 169.115816826
BXD16 m 442.0 140.6231058426 719.6160530871 164.3839469129
BXD27 m 514.0 157.2214119356 824.384183174 203.615816826
BXD32 m 224.6666666667 181.5436490068 583.067450082 -133.7341167487
BXD34 m 279.8 140.6231058426 557.4160530871 2.1839469129
BXD39 m 1950.8 140.6231058426 2228.4160530871 1673.1839469129
BXD40 m 183.5 157.2214119356 493.884183174 -126.884183174
BXD43 m 214.3333333333 181.5436490068 572.7341167487 -144.067450082
BXD44 m 672.4 140.6231058426 950.0160530871 394.7839469129
BXD45 m 296.0 157.2214119356 606.384183174 -14.384183174
BXD48 m 280.2 140.6231058426 557.8160530871 2.5839469129
BXD48a m 396.6666666667 181.5436490068 755.067450082 38.2658832513
BXD49 m 303.75 157.2214119356 614.134183174 -6.634183174
BXD50 m 270.2 140.6231058426 547.8160530871 -7.4160530871
BXD51 m 338.0 157.2214119356 648.384183174 27.615816826
BXD53 m 929.4 140.6231058426 1207.0160530871 651.7839469129
BXD55 m 144.0 157.2214119356 454.384183174 -166.384183174
BXD56 m 406.5 222.3446530548 845.4495213907 -32.4495213907
BXD6 m 293.6 140.6231058426 571.2160530871 15.9839469129
BXD60 m 2109.0 157.2214119356 2419.384183174 1798.6158168261
BXD61 m 464.8 140.6231058426 742.4160530871 187.1839469129
BXD62 m 891.0 157.2214119356 1201.384183174 580.615816826
BXD63 m 1032.5 222.3446530548 1471.4495213907 593.5504786093
BXD64 m 539.0 157.2214119356 849.384183174 228.615816826
BXD65 m 707.0 157.2214119356 1017.384183174 396.615816826
BXD65a m 398.0 157.2214119356 708.384183174 87.615816826
BXD66 m 235.0 157.2214119356 545.384183174 -75.384183174
BXD67 m 798.2 140.6231058426 1075.8160530871 520.5839469129
BXD68 m 281.75 157.2214119356 592.134183174 -28.634183174
BXD69 m 503.6 140.6231058426 781.2160530871 225.9839469129
BXD70 m 400.0 181.5436490068 758.4007834154 41.5992165846
BXD71 m 445.0 181.5436490068 803.4007834154 86.5992165846
BXD73 m 237.75 157.2214119356 548.134183174 -72.634183174
BXD73a m 330.8 140.6231058426 608.4160530871 53.1839469129
BXD73b m 386.4 140.6231058426 664.0160530871 108.7839469129
BXD75 m 216.4 140.6231058426 494.0160530871 -61.2160530871
BXD77 m 295.6 140.6231058426 573.2160530871 17.9839469129
BXD79 m 426.2 140.6231058426 703.8160530871 148.5839469129
BXD81 m 614.3333333333 181.5436490068 972.7341167487 255.932549918
BXD83 m 535.25 157.2214119356 845.634183174 224.865816826
BXD84 m 330.6666666667 181.5436490068 689.067450082 -27.7341167487
BXD85 m 688.75 157.2214119356 999.134183174 378.365816826
BXD87 m 392.0 140.6231058426 669.6160530871 114.3839469129
BXD89 m 480.25 157.2214119356 790.634183174 169.865816826
BXD90 m 355.5 157.2214119356 665.884183174 45.115816826
BXD95 m 370.0 157.2214119356 680.384183174 59.615816826
BXD98 m 1392.0 140.6231058426 1669.6160530871 1114.3839469129
BXD99 m 354.4 140.6231058426 632.0160530871 76.7839469129
C57BL/6J m 146.8 140.6231058426 424.4160530871 -130.8160530871
DBA/2J m 71.6 140.6231058426 349.2160530871 -206.0160530871




  GWAS USING LINEAR MIXED MODELS