Project measure / variable:   Auwerx1   ldh_CD

ID, description, units MPD:111364   ldh_CD   blood lactate dehydrogenase (LDH) amount   [U/L]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   54 strains     sex: m     age: 29wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx1 - blood lactate dehydrogenase (LDH) amount CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested54 strains
Mean of the strain means254.1   U/L
Median of the strain means233.4   U/L
SD of the strain means± 129.9
Coefficient of variation (CV)0.5111
Min–max range of strain means43.0   –   745.6   U/L
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 53 4065896.2324 76715.0233 4.5166 < 0.0001
Residuals 173 2938397.5738 16984.9571


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 282.0 120.1   5 53.72 0.426 139.0, 447.0 0.21
BXD100 m 107.0 37.51   3 21.656 0.3506 81.0, 150.0 -1.13
BXD101 m 296.0 93.62   4 46.812 0.3163 220.0, 430.0 0.32
BXD12 m 303.8 153.8   5 68.79 0.5063 157.0, 555.0 0.38
BXD16 m 378.2 55.91   4 27.956 0.1478 315.0, 451.0 0.96
BXD27 m 171.6 39.177   5 17.52 0.2283 140.0, 240.0 -0.64
BXD32 m 149.2 85.33   5 38.162 0.5719 84.0, 296.0 -0.81
BXD34 m 140.8 16.761   4 8.3803 0.1191 116.0, 152.0 -0.87
BXD39 m 745.6 391.3   5 175.0 0.5248 262.0, 1298.0 3.78
BXD40 m 194.7 129.4   3 74.7 0.6647 116.0, 344.0 -0.46
BXD43 m 214.0 24.269   3 14.012 0.1134 194.0, 241.0 -0.31
BXD44 m 482.9 297.2   7 112.3 0.6155 82.0, 936.0 1.76
BXD45 m 231.0 82.26   5 36.787 0.3561 128.0, 347.0 -0.18
BXD48 m 130.0 23.377   5 10.455 0.1798 104.0, 156.0 -0.96
BXD48a m 109.0 116.7   5 52.19 1.0706 8.0, 245.0 -1.12
BXD49 m 196.5 60.73   4 30.366 0.3091 155.0, 286.0 -0.44
BXD50 m 170.0 27.41   4 13.705 0.1612 135.0, 202.0 -0.65
BXD51 m 95.33 36.143   3 20.867 0.3791 54.0, 121.0 -1.22
BXD53 m 233.0 20.801   4 10.4 0.0893 203.0, 250.0 -0.16
BXD55 m 163.0 132.7   5 59.36 0.8143 15.0, 344.0 -0.7
BXD56 m 296.0 159.0   3 91.78 0.5371 192.0, 479.0 0.32
BXD6 m 180.5 42.54   4 21.27 0.2357 128.0, 229.0 -0.57
BXD60 m 622.5 225.2   4 112.6 0.3618 413.0, 916.0 2.84
BXD61 m 277.7 193.4   3 111.7 0.6966 141.0, 499.0 0.18
BXD62 m 273.2 46.992   4 23.496 0.172 223.0, 335.0 0.15
BXD63 m 201.3 17.616   3 10.171 0.0875 185.0, 220.0 -0.41
BXD64 m 251.2 82.86   4 41.431 0.3298 181.0, 364.0 -0.02
BXD65 m 444.5 124.2   4 62.09 0.2794 289.0, 573.0 1.47
BXD65a m 400.4 191.6   5 85.67 0.4785 234.0, 719.0 1.13
BXD65b m 411.0 147.3   4 73.63 0.3583 213.0, 568.0 1.21
BXD66 m 211.6 66.66   5 29.81 0.315 148.0, 319.0 -0.33
BXD67 m 231.5 95.34   4 47.67 0.4118 113.0, 332.0 -0.17
BXD68 m 396.3 180.0   3 103.9 0.4542 255.0, 599.0 1.09
BXD69 m 435.8 199.7   5 89.29 0.4582 247.0, 727.0 1.4
BXD70 m 179.8 154.2   4 77.12 0.8581 39.0, 366.0 -0.57
BXD71 m 236.2 89.23   4 44.616 0.3777 187.0, 370.0 -0.14
BXD73 m 84.25 30.631   4 15.315 0.3636 55.0, 115.0 -1.31
BXD73a m 135.6 90.83   5 40.621 0.6698 6.0, 234.0 -0.91
BXD73b m 353.8 119.5   5 53.42 0.3376 252.0, 553.0 0.77
BXD75 m 149.8 93.45   5 41.79 0.6238 41.0, 286.0 -0.8
BXD77 m 193.8 119.0   4 59.49 0.614 100.0, 357.0 -0.46
BXD79 m 350.0 86.55   5 38.707 0.2473 199.0, 419.0 0.74
BXD81 m 239.0 104.0   4 52.02 0.4353 145.0, 385.0 -0.12
BXD83 m 302.3 98.8   3 57.04 0.3268 237.0, 416.0 0.37
BXD84 m 290.7 116.9   3 67.47 0.4021 206.0, 424.0 0.28
BXD85 m 233.8 61.19   5 27.365 0.2617 173.0, 328.0 -0.16
BXD87 m 158.6 120.3   5 53.8 0.7585 17.0, 274.0 -0.74
BXD89 m 249.2 54.24   4 27.121 0.2176 177.0, 300.0 -0.04
BXD90 m 169.0 36.851   4 18.426 0.2181 140.0, 223.0 -0.66
BXD95 m 237.8 45.294   4 22.647 0.1905 170.0, 265.0 -0.13
BXD98 m 242.0 67.51   3 38.974 0.2789 189.0, 318.0 -0.09
BXD99 m 280.2 50.36   5 22.52 0.1797 212.0, 353.0 0.2
C57BL/6J m 165.8 109.8   4 54.88 0.6622 83.0, 325.0 -0.68
DBA/2J m 43.0 28.554   4 14.277 0.664 6.0, 66.0 -1.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 282.0 58.2837148336 397.038725746 166.961274254
BXD100 m 107.0 75.2439523019 255.5143563277 -41.5143563277
BXD101 m 296.0 65.1631741746 424.6172054065 167.3827945935
BXD12 m 303.8 58.2837148336 418.838725746 188.761274254
BXD16 m 378.25 65.1631741746 506.8672054065 249.6327945935
BXD27 m 171.6 58.2837148336 286.638725746 56.561274254
BXD32 m 149.2 58.2837148336 264.238725746 34.161274254
BXD34 m 140.75 65.1631741746 269.3672054065 12.1327945935
BXD39 m 745.6 58.2837148336 860.638725746 630.561274254
BXD40 m 194.6666666667 75.2439523019 343.1810229943 46.152310339
BXD43 m 214.0 75.2439523019 362.5143563277 65.4856436723
BXD44 m 482.8571428571 49.258729573 580.0826113799 385.6316743344
BXD45 m 231.0 58.2837148336 346.038725746 115.961274254
BXD48 m 130.0 58.2837148336 245.038725746 14.961274254
BXD48a m 109.0 58.2837148336 224.038725746 -6.038725746
BXD49 m 196.5 65.1631741746 325.1172054065 67.8827945935
BXD50 m 170.0 65.1631741746 298.6172054065 41.3827945935
BXD51 m 95.3333333333 75.2439523019 243.847689661 -53.1810229943
BXD53 m 233.0 65.1631741746 361.6172054065 104.3827945935
BXD55 m 163.0 58.2837148336 278.038725746 47.961274254
BXD56 m 296.0 75.2439523019 444.5143563277 147.4856436723
BXD6 m 180.5 65.1631741746 309.1172054065 51.8827945935
BXD60 m 622.5 65.1631741746 751.1172054065 493.8827945935
BXD61 m 277.6666666667 75.2439523019 426.1810229943 129.152310339
BXD62 m 273.25 65.1631741746 401.8672054065 144.6327945935
BXD63 m 201.3333333333 75.2439523019 349.847689661 52.8189770057
BXD64 m 251.25 65.1631741746 379.8672054065 122.6327945935
BXD65 m 444.5 65.1631741746 573.1172054065 315.8827945935
BXD65a m 400.4 58.2837148336 515.438725746 285.361274254
BXD65b m 411.0 65.1631741746 539.6172054065 282.3827945935
BXD66 m 211.6 58.2837148336 326.638725746 96.561274254
BXD67 m 231.5 65.1631741746 360.1172054065 102.8827945935
BXD68 m 396.3333333333 75.2439523019 544.847689661 247.8189770057
BXD69 m 435.8 58.2837148336 550.838725746 320.761274254
BXD70 m 179.75 65.1631741746 308.3672054065 51.1327945935
BXD71 m 236.25 65.1631741746 364.8672054065 107.6327945935
BXD73 m 84.25 65.1631741746 212.8672054065 -44.3672054065
BXD73a m 135.6 58.2837148336 250.638725746 20.561274254
BXD73b m 353.8 58.2837148336 468.838725746 238.761274254
BXD75 m 149.8 58.2837148336 264.838725746 34.761274254
BXD77 m 193.75 65.1631741746 322.3672054065 65.1327945935
BXD79 m 350.0 58.2837148336 465.038725746 234.961274254
BXD81 m 239.0 65.1631741746 367.6172054065 110.3827945935
BXD83 m 302.3333333333 75.2439523019 450.847689661 153.8189770057
BXD84 m 290.6666666667 75.2439523019 439.1810229943 142.152310339
BXD85 m 233.8 58.2837148336 348.838725746 118.761274254
BXD87 m 158.6 58.2837148336 273.638725746 43.561274254
BXD89 m 249.25 65.1631741746 377.8672054065 120.6327945935
BXD90 m 169.0 65.1631741746 297.6172054065 40.3827945935
BXD95 m 237.75 65.1631741746 366.3672054065 109.1327945935
BXD98 m 242.0 75.2439523019 390.5143563277 93.4856436723
BXD99 m 280.2 58.2837148336 395.238725746 165.161274254
C57BL/6J m 165.75 65.1631741746 294.3672054065 37.1327945935
DBA/2J m 43.0 65.1631741746 171.6172054065 -85.6172054065




  GWAS USING LINEAR MIXED MODELS