Project measure / variable:   Auwerx1   creatinine_HFD

ID, description, units MPD:111353   creatinine_HFD   blood creatinine amount   [µmol/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   43 strains     sex: m     age: 29wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx1 - blood creatinine amount HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested43 strains
Mean of the strain means16.097   µmol/L
Median of the strain means17.6   µmol/L
SD of the strain means± 8.9897
Coefficient of variation (CV)0.5585
Min–max range of strain means1.0   –   32.5   µmol/L
Mean sample size per strain3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 36 8241.9086 228.9419 6.8039 < 0.0001
Residuals 108 3634.05 33.6486


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 6.6667 3.0551   3 1.7638 0.4583 4.0, 10.0 -1.05
BXD100 m 25.2 3.8987   5 1.7436 0.1547 20.0, 29.0 1.01
BXD101 m 16.25 2.2174   4 1.1087 0.1365 13.0, 18.0 0.02
BXD16 m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -1.46
BXD32 m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.35
BXD34 m 3.0 0.0   2   0.0 0.0 3.0, 3.0 -1.46
BXD39 m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.68
BXD40 m 7.3333 6.1101   3 3.5277 0.8332 2.0, 14.0 -0.97
BXD43 m 8.6667 2.5166   3 1.453 0.2904 6.0, 11.0 -0.83
BXD44 m 32.5 3.5355   2   2.5 0.1088 30.0, 35.0 1.82
BXD45 m 26.0 4.8305   4 2.4152 0.1858 22.0, 33.0 1.1
BXD48 m 5.5 1.9149   4 0.95743 0.3482 4.0, 8.0 -1.18
BXD49 m 15.25 5.1235   4 2.5617 0.336 8.0, 20.0 -0.09
BXD50 m 15.4 7.5033   5 3.3556 0.4872 4.0, 23.0 -0.08
BXD51 m 19.25 3.2016   4 1.6008 0.1663 16.0, 22.0 0.35
BXD55 m 28.75 9.3229   4 4.6615 0.3243 21.0, 41.0 1.41
BXD56 m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -1.12
BXD6 m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.35
BXD60 m 18.5 9.1833   4 4.5917 0.4964 6.0, 28.0 0.27
BXD61 m 26.2 2.7749   5 1.241 0.1059 24.0, 31.0 1.12
BXD64 m 7.5 3.5355   2   2.5 0.4714 5.0, 10.0 -0.96
BXD65 m 10.5 2.0817   4 1.0408 0.1983 8.0, 13.0 -0.62
BXD65a m 20.5 1.7321   4 0.86603 0.0845 19.0, 22.0 0.49
BXD68 m 21.5 4.5092   4 2.2546 0.2097 18.0, 28.0 0.6
BXD69 m 7.5 7.1414   4 3.5707 0.9522 2.0, 18.0 -0.96
BXD70 m 24.333 5.5076   3 3.1798 0.2263 19.0, 30.0 0.92
BXD71 m 24.0 0.0   1   0.0 0.0 24.0, 24.0 0.88
BXD73 m 27.5 3.7859   4 1.893 0.1377 22.0, 30.0 1.27
BXD73a m 20.8 5.0695   5 2.2672 0.2437 14.0, 26.0 0.52
BXD73b m 24.75 7.4106   4 3.7053 0.2994 15.0, 33.0 0.96
BXD75 m 22.2 5.7619   5 2.5768 0.2595 16.0, 28.0 0.68
BXD77 m 8.75 4.272   4 2.136 0.4882 3.0, 12.0 -0.82
BXD79 m 18.2 3.8341   5 1.7146 0.2107 16.0, 25.0 0.23
BXD81 m 5.0 2.8284   2   2.0 0.5657 3.0, 7.0 -1.23
BXD84 m 7.3333 3.0551   3 1.7638 0.4166 4.0, 10.0 -0.97
BXD85 m 23.25 10.689   4 5.3444 0.4597 13.0, 36.0 0.8
BXD87 m 28.8 7.0143   5 3.1369 0.2436 20.0, 38.0 1.41
BXD89 m 9.6667 5.1316   3 2.9627 0.5309 4.0, 14.0 -0.72
BXD95 m 16.0 4.3205   4 2.1602 0.27 10.0, 20.0 -0.01
BXD98 m 22.2 8.2583   5 3.6932 0.372 8.0, 28.0 0.68
BXD99 m 17.6 9.7877   5 4.3772 0.5561 7.0, 29.0 0.17
C57BL/6J m 26.0 4.4159   5 1.9748 0.1698 20.0, 31.0 1.1
DBA/2J m 25.8 7.1554   5 3.2 0.2773 19.0, 36.0 1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 6.6666666667 3.3490601224 13.3050848354 0.028248498
BXD100 m 25.2 2.5941708159 30.3420966025 20.0579033975
BXD101 m 16.25 2.9003711448 21.999038775 10.500961225
BXD34 m 3.0 4.1017442089 11.1303686063 -5.1303686063
BXD40 m 7.3333333333 3.3490601224 13.971751502 0.6949151646
BXD43 m 8.6666666667 3.3490601224 15.3050848354 2.028248498
BXD44 m 32.5 4.1017442089 40.6303686063 24.3696313937
BXD45 m 26.0 2.9003711448 31.749038775 20.250961225
BXD48 m 5.5 2.9003711448 11.249038775 -0.249038775
BXD49 m 15.25 2.9003711448 20.999038775 9.500961225
BXD50 m 15.4 2.5941708159 20.5420966025 10.2579033975
BXD51 m 19.25 2.9003711448 24.999038775 13.500961225
BXD55 m 28.75 2.9003711448 34.499038775 23.000961225
BXD60 m 18.5 2.9003711448 24.249038775 12.750961225
BXD61 m 26.2 2.5941708159 31.3420966025 21.0579033975
BXD64 m 7.5 4.1017442089 15.6303686063 -0.6303686063
BXD65 m 10.5 2.9003711448 16.249038775 4.750961225
BXD65a m 20.5 2.9003711448 26.249038775 14.750961225
BXD68 m 21.5 2.9003711448 27.249038775 15.750961225
BXD69 m 7.5 2.9003711448 13.249038775 1.750961225
BXD70 m 24.3333333333 3.3490601224 30.971751502 17.6949151646
BXD73 m 27.5 2.9003711448 33.249038775 21.750961225
BXD73a m 20.8 2.5941708159 25.9420966025 15.6579033975
BXD73b m 24.75 2.9003711448 30.499038775 19.000961225
BXD75 m 22.2 2.5941708159 27.3420966025 17.0579033975
BXD77 m 8.75 2.9003711448 14.499038775 3.000961225
BXD79 m 18.2 2.5941708159 23.3420966025 13.0579033975
BXD81 m 5.0 4.1017442089 13.1303686063 -3.1303686063
BXD84 m 7.3333333333 3.3490601224 13.971751502 0.6949151646
BXD85 m 23.25 2.9003711448 28.999038775 17.500961225
BXD87 m 28.8 2.5941708159 33.9420966025 23.6579033975
BXD89 m 9.6666666667 3.3490601224 16.3050848354 3.028248498
BXD95 m 16.0 2.9003711448 21.749038775 10.250961225
BXD98 m 22.2 2.5941708159 27.3420966025 17.0579033975
BXD99 m 17.6 2.5941708159 22.7420966025 12.4579033975
C57BL/6J m 26.0 2.5941708159 31.1420966025 20.8579033975
DBA/2J m 25.8 2.5941708159 30.9420966025 20.6579033975




  GWAS USING LINEAR MIXED MODELS