Project measure / variable:   Auwerx1   creatinine_CD

ID, description, units MPD:111352   creatinine_CD   blood creatinine amount   [µmol/L]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   44 strains     sex: m     age: 29wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx1 - blood creatinine amount CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested44 strains
Mean of the strain means16.101   µmol/L
Median of the strain means14.9   µmol/L
SD of the strain means± 8.2503
Coefficient of variation (CV)0.5124
Min–max range of strain means3.0   –   32.25   µmol/L
Mean sample size per strain3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 41 10571.649 257.8451 7.5585 < 0.0001
Residuals 125 4264.1833 34.1135


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.0 1.8708   5 0.83666 0.6236 1.0, 6.0 -1.59
BXD100 m 29.0 5.2915   3 3.0551 0.1825 23.0, 33.0 1.56
BXD101 m 18.5 3.5355   2   2.5 0.1911 16.0, 21.0 0.29
BXD12 m 5.75 4.113   4 2.0565 0.7153 2.0, 11.0 -1.25
BXD27 m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -1.59
BXD32 m 9.3333 6.0277   3 3.4801 0.6458 3.0, 15.0 -0.82
BXD34 m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.47
BXD39 m 6.0 5.0498   5 2.2583 0.8416 2.0, 12.0 -1.22
BXD40 m 18.667 2.5166   3 1.453 0.1348 16.0, 21.0 0.31
BXD43 m 11.333 1.5275   3 0.88192 0.1348 10.0, 13.0 -0.58
BXD44 m 24.25 3.4034   4 1.7017 0.1403 21.0, 29.0 0.99
BXD45 m 29.2 4.3243   5 1.9339 0.1481 22.0, 33.0 1.59
BXD48 m 11.25 4.7871   4 2.3936 0.4255 6.0, 17.0 -0.59
BXD48a m 22.2 2.5884   5 1.1576 0.1166 19.0, 26.0 0.74
BXD49 m 10.5 7.8528   4 3.9264 0.7479 5.0, 22.0 -0.68
BXD50 m 13.5 1.7321   4 0.86603 0.1283 11.0, 15.0 -0.32
BXD51 m 22.333 9.2916   3 5.3645 0.416 16.0, 33.0 0.76
BXD55 m 21.0 3.0822   5 1.3784 0.1468 19.0, 26.0 0.59
BXD56 m 10.333 7.7675   3 4.4845 0.7517 4.0, 19.0 -0.7
BXD60 m 7.5 5.1962   4 2.5981 0.6928 4.0, 15.0 -1.04
BXD61 m 29.333 6.0277   3 3.4801 0.2055 23.0, 35.0 1.6
BXD64 m 11.0 3.6515   4 1.8257 0.332 7.0, 15.0 -0.62
BXD65 m 12.5 7.0475   4 3.5237 0.5638 6.0, 20.0 -0.44
BXD65a m 11.0 3.7417   5 1.6733 0.3402 5.0, 15.0 -0.62
BXD65b m 5.3333 3.5119   3 2.0276 0.6585 2.0, 9.0 -1.31
BXD68 m 15.0 6.0   3 3.4641 0.4 9.0, 21.0 -0.13
BXD69 m 11.6 3.7815   5 1.6912 0.326 8.0, 17.0 -0.55
BXD70 m 20.75 4.9244   4 2.4622 0.2373 16.0, 25.0 0.56
BXD71 m 32.25 7.6322   4 3.8161 0.2367 23.0, 39.0 1.96
BXD73 m 23.5 5.1962   4 2.5981 0.2211 19.0, 31.0 0.9
BXD73a m 27.8 14.446   5 6.4607 0.5197 17.0, 53.0 1.42
BXD73b m 14.8 12.538   5 5.6071 0.8472 5.0, 29.0 -0.16
BXD75 m 29.4 6.0663   5 2.7129 0.2063 21.0, 38.0 1.61
BXD77 m 14.5 6.3509   4 3.1754 0.438 8.0, 23.0 -0.19
BXD79 m 19.4 3.2094   5 1.4353 0.1654 15.0, 22.0 0.4
BXD81 m 3.3333 3.2146   3 1.8559 0.9644 1.0, 7.0 -1.55
BXD84 m 20.0 10.817   3 6.245 0.5408 8.0, 29.0 0.47
BXD85 m 22.2 4.5497   5 2.0347 0.2049 18.0, 29.0 0.74
BXD87 m 23.2 3.4205   5 1.5297 0.1474 18.0, 27.0 0.86
BXD95 m 15.25 1.7078   4 0.85391 0.112 13.0, 17.0 -0.1
BXD98 m 13.5 2.1213   2   1.5 0.1571 12.0, 15.0 -0.32
BXD99 m 7.4 5.4129   5 2.4207 0.7315 1.0, 13.0 -1.05
C57BL/6J m 23.5 1.7321   4 0.86603 0.0737 21.0, 25.0 0.9
DBA/2J m 21.25 3.2016   4 1.6008 0.1507 19.0, 26.0 0.62


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.0 2.6120285859 8.1695287488 -2.1695287488
BXD100 m 29.0 3.3721144043 35.6738329172 22.3261670828
BXD101 m 18.5 4.1299798224 26.6737426379 10.3262573621
BXD12 m 5.75 2.9203367386 11.5297088469 -0.0297088469
BXD32 m 9.3333333333 3.3721144043 16.0071662506 2.6595004161
BXD39 m 6.0 2.6120285859 11.1695287488 0.8304712512
BXD40 m 18.6666666667 3.3721144043 25.3404995839 11.9928337494
BXD43 m 11.3333333333 3.3721144043 18.0071662506 4.6595004161
BXD44 m 24.25 2.9203367386 30.0297088469 18.4702911531
BXD45 m 29.2 2.6120285859 34.3695287488 24.0304712512
BXD48 m 11.25 2.9203367386 17.0297088469 5.4702911531
BXD48a m 22.2 2.6120285859 27.3695287488 17.0304712512
BXD49 m 10.5 2.9203367386 16.2797088469 4.7202911531
BXD50 m 13.5 2.9203367386 19.2797088469 7.7202911531
BXD51 m 22.3333333333 3.3721144043 29.0071662506 15.6595004161
BXD55 m 21.0 2.6120285859 26.1695287488 15.8304712512
BXD56 m 10.3333333333 3.3721144043 17.0071662506 3.6595004161
BXD60 m 7.5 2.9203367386 13.2797088469 1.7202911531
BXD61 m 29.3333333333 3.3721144043 36.0071662506 22.6595004161
BXD64 m 11.0 2.9203367386 16.7797088469 5.2202911531
BXD65 m 12.5 2.9203367386 18.2797088469 6.7202911531
BXD65a m 11.0 2.6120285859 16.1695287488 5.8304712512
BXD65b m 5.3333333333 3.3721144043 12.0071662506 -1.3404995839
BXD68 m 15.0 3.3721144043 21.6738329172 8.3261670828
BXD69 m 11.6 2.6120285859 16.7695287488 6.4304712512
BXD70 m 20.75 2.9203367386 26.5297088469 14.9702911531
BXD71 m 32.25 2.9203367386 38.0297088469 26.4702911531
BXD73 m 23.5 2.9203367386 29.2797088469 17.7202911531
BXD73a m 27.8 2.6120285859 32.9695287488 22.6304712512
BXD73b m 14.8 2.6120285859 19.9695287488 9.6304712512
BXD75 m 29.4 2.6120285859 34.5695287488 24.2304712512
BXD77 m 14.5 2.9203367386 20.2797088469 8.7202911531
BXD79 m 19.4 2.6120285859 24.5695287488 14.2304712512
BXD81 m 3.3333333333 3.3721144043 10.0071662506 -3.3404995839
BXD84 m 20.0 3.3721144043 26.6738329172 13.3261670828
BXD85 m 22.2 2.6120285859 27.3695287488 17.0304712512
BXD87 m 23.2 2.6120285859 28.3695287488 18.0304712512
BXD95 m 15.25 2.9203367386 21.0297088469 9.4702911531
BXD98 m 13.5 4.1299798224 21.6737426379 5.3262573621
BXD99 m 7.4 2.6120285859 12.5695287488 2.2304712512
C57BL/6J m 23.5 2.9203367386 29.2797088469 17.7202911531
DBA/2J m 21.25 2.9203367386 27.0297088469 15.4702911531




  GWAS USING LINEAR MIXED MODELS