Project measure / variable:   Auwerx1   creatine_kin_HFD

ID, description, units MPD:111351   creatine_kin_HFD   blood creatine kinase amount   [U/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   52 strains     sex: m     age: 29wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx1 - blood creatine kinase amount HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested52 strains
Mean of the strain means112.6   U/L
Median of the strain means98.62   U/L
SD of the strain means± 69.22
Coefficient of variation (CV)0.6146
Min–max range of strain means11.2   –   292.5   U/L
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 51 1000306.0971 19613.845 1.5456 0.0213
Residuals 166 2106540.4167 12690.0025


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 98.0 34.569   5 15.46 0.3527 57.0, 150.0 -0.21
BXD100 m 65.6 40.863   5 18.275 0.6229 19.0, 113.0 -0.68
BXD101 m 55.75 17.652   4 8.8259 0.3166 35.0, 78.0 -0.82
BXD16 m 127.2 136.6   5 61.11 1.0742 47.0, 369.0 0.21
BXD27 m 282.5 363.9   4 182.0 1.2883 82.0, 828.0 2.45
BXD32 m 96.67 112.9   3 65.17 1.1677 30.0, 227.0 -0.23
BXD34 m 70.4 45.33   5 20.272 0.6439 42.0, 151.0 -0.61
BXD39 m 108.0 38.67   4 19.335 0.3581 71.0, 151.0 -0.07
BXD40 m 123.0 55.19   4 27.595 0.4487 80.0, 198.0 0.15
BXD43 m 131.7 134.6   3 77.7 1.0221 50.0, 287.0 0.28
BXD44 m 242.2 211.3   5 94.48 0.8723 73.0, 549.0 1.87
BXD45 m 117.0 149.7   4 74.86 1.2797 13.0, 334.0 0.06
BXD48 m 106.2 76.89   5 34.387 0.724 39.0, 214.0 -0.09
BXD48a m 50.67 26.16   3 15.103 0.5163 23.0, 75.0 -0.9
BXD49 m 71.25 27.085   4 13.542 0.3801 35.0, 100.0 -0.6
BXD50 m 72.8 36.472   5 16.311 0.501 39.0, 132.0 -0.58
BXD51 m 26.5 5.3229   4 2.6615 0.2009 21.0, 32.0 -1.24
BXD53 m 119.0 24.806   4 12.403 0.2085 82.0, 135.0 0.09
BXD55 m 149.8 252.6   4 126.3 1.6867 8.0, 528.0 0.54
BXD56 m 83.0 21.213   2   15.0 0.2556 68.0, 98.0 -0.43
BXD6 m 59.0 17.944   5 8.025 0.3041 40.0, 88.0 -0.77
BXD60 m 241.2 239.5   4 119.8 0.9928 57.0, 592.0 1.86
BXD61 m 52.0 36.256   5 16.214 0.6972 21.0, 114.0 -0.88
BXD62 m 208.2 126.2   4 63.08 0.6058 78.0, 338.0 1.38
BXD63 m 122.5 77.07   2   54.5 0.6292 68.0, 177.0 0.14
BXD64 m 79.0 22.686   4 11.343 0.2872 67.0, 113.0 -0.49
BXD65 m 127.2 41.86   4 20.93 0.329 91.0, 184.0 0.21
BXD65a m 100.8 10.404   4 5.2022 0.1033 93.0, 115.0 -0.17
BXD66 m 77.25 46.478   4 23.239 0.6017 35.0, 131.0 -0.51
BXD67 m 92.0 23.108   5 10.334 0.2512 70.0, 118.0 -0.3
BXD68 m 110.0 19.9   4 9.9499 0.1809 85.0, 127.0 -0.04
BXD69 m 157.0 78.95   5 35.306 0.5028 52.0, 230.0 0.64
BXD70 m 29.333 1.5275   3 0.88192 0.0521 28.0, 31.0 -1.2
BXD71 m 117.7 49.662   3 28.672 0.4221 63.0, 160.0 0.07
BXD73 m 17.0 5.7735   4 2.8868 0.3396 12.0, 22.0 -1.38
BXD73a m 41.8 30.409   5 13.599 0.7275 15.0, 89.0 -1.02
BXD73b m 103.2 28.778   5 12.87 0.2789 80.0, 151.0 -0.14
BXD75 m 55.0 53.86   5 24.087 0.9793 24.0, 151.0 -0.83
BXD77 m 64.6 8.735   5 3.9064 0.1352 54.0, 77.0 -0.69
BXD79 m 113.6 53.73   5 24.028 0.473 71.0, 187.0 0.01
BXD81 m 251.7 261.9   3 151.2 1.0408 93.0, 554.0 2.01
BXD83 m 237.0 195.4   4 97.68 0.8243 94.0, 522.0 1.8
BXD84 m 77.67 12.858   3 7.4237 0.1656 63.0, 87.0 -0.51
BXD85 m 267.2 187.4   4 93.71 0.7013 116.0, 541.0 2.23
BXD87 m 77.4 51.8   5 23.164 0.6692 21.0, 141.0 -0.51
BXD89 m 292.5 303.8   4 151.9 1.0387 60.0, 700.0 2.6
BXD90 m 68.75 61.08   4 30.541 0.8885 28.0, 159.0 -0.63
BXD95 m 99.25 41.508   4 20.754 0.4182 55.0, 152.0 -0.19
BXD98 m 88.0 18.069   5 8.0808 0.2053 62.0, 109.0 -0.36
BXD99 m 74.4 16.319   5 7.2979 0.2193 47.0, 87.0 -0.55
C57BL/6J m 146.4 152.4   5 68.16 1.041 19.0, 385.0 0.49
DBA/2J m 11.2 4.6043   5 2.0591 0.4111 6.0, 16.0 -1.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 98.0 50.3785718536 197.4653244612 -1.4653244612
BXD100 m 65.6 50.3785718536 165.0653244612 -33.8653244612
BXD101 m 55.75 56.324955637 166.9556134496 -55.4556134496
BXD16 m 127.2 50.3785718536 226.6653244612 27.7346755388
BXD27 m 282.5 56.324955637 393.7056134496 171.2943865504
BXD32 m 96.6666666667 65.0384565982 225.0758483877 -31.7425150544
BXD34 m 70.4 50.3785718536 169.8653244612 -29.0653244612
BXD39 m 108.0 56.324955637 219.2056134496 -3.2056134496
BXD40 m 123.0 56.324955637 234.2056134496 11.7943865504
BXD43 m 131.6666666667 65.0384565982 260.0758483877 3.2574849456
BXD44 m 242.2 50.3785718536 341.6653244612 142.7346755388
BXD45 m 117.0 56.324955637 228.2056134496 5.7943865504
BXD48 m 106.2 50.3785718536 205.6653244612 6.7346755388
BXD48a m 50.6666666667 65.0384565982 179.0758483877 -77.7425150544
BXD49 m 71.25 56.324955637 182.4556134496 -39.9556134496
BXD50 m 72.8 50.3785718536 172.2653244612 -26.6653244612
BXD51 m 26.5 56.324955637 137.7056134496 -84.7056134496
BXD53 m 119.0 56.324955637 230.2056134496 7.7943865504
BXD55 m 149.75 56.324955637 260.9556134496 38.5443865504
BXD56 m 83.0 79.6555161619 240.2684867525 -74.2684867525
BXD6 m 59.0 50.3785718536 158.4653244612 -40.4653244612
BXD60 m 241.25 56.324955637 352.4556134496 130.0443865504
BXD61 m 52.0 50.3785718536 151.4653244612 -47.4653244612
BXD62 m 208.25 56.324955637 319.4556134496 97.0443865504
BXD63 m 122.5 79.6555161619 279.7684867525 -34.7684867525
BXD64 m 79.0 56.324955637 190.2056134496 -32.2056134496
BXD65 m 127.25 56.324955637 238.4556134496 16.0443865504
BXD65a m 100.75 56.324955637 211.9556134496 -10.4556134496
BXD66 m 77.25 56.324955637 188.4556134496 -33.9556134496
BXD67 m 92.0 50.3785718536 191.4653244612 -7.4653244612
BXD68 m 110.0 56.324955637 221.2056134496 -1.2056134496
BXD69 m 157.0 50.3785718536 256.4653244612 57.5346755388
BXD70 m 29.3333333333 65.0384565982 157.7425150544 -99.0758483877
BXD71 m 117.6666666667 65.0384565982 246.0758483877 -10.7425150544
BXD73 m 17.0 56.324955637 128.2056134496 -94.2056134496
BXD73a m 41.8 50.3785718536 141.2653244612 -57.6653244612
BXD73b m 103.2 50.3785718536 202.6653244612 3.7346755388
BXD75 m 55.0 50.3785718536 154.4653244612 -44.4653244612
BXD77 m 64.6 50.3785718536 164.0653244612 -34.8653244612
BXD79 m 113.6 50.3785718536 213.0653244612 14.1346755388
BXD81 m 251.6666666667 65.0384565982 380.0758483877 123.2574849456
BXD83 m 237.0 56.324955637 348.2056134496 125.7943865504
BXD84 m 77.6666666667 65.0384565982 206.0758483877 -50.7425150544
BXD85 m 267.25 56.324955637 378.4556134496 156.0443865504
BXD87 m 77.4 50.3785718536 176.8653244612 -22.0653244612
BXD89 m 292.5 56.324955637 403.7056134496 181.2943865504
BXD90 m 68.75 56.324955637 179.9556134496 -42.4556134496
BXD95 m 99.25 56.324955637 210.4556134496 -11.9556134496
BXD98 m 88.0 50.3785718536 187.4653244612 -11.4653244612
BXD99 m 74.4 50.3785718536 173.8653244612 -25.0653244612
C57BL/6J m 146.4 50.3785718536 245.8653244612 46.9346755388
DBA/2J m 11.2 50.3785718536 110.6653244612 -88.2653244612




  GWAS USING LINEAR MIXED MODELS