Project measure / variable:   Auwerx1   creatine_kin_CD

ID, description, units MPD:111350   creatine_kin_CD   blood creatine kinase amount   [U/L]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   54 strains     sex: m     age: 29wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx1 - blood creatine kinase amount CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested54 strains
Mean of the strain means158.5   U/L
Median of the strain means124.5   U/L
SD of the strain means± 130.5
Coefficient of variation (CV)0.8238
Min–max range of strain means3.0   –   684.0   U/L
Mean sample size per strain4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 52 3729608.9455 71723.249 1.7117 0.0056
Residuals 169 7081347.2167 41901.4628


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 530.0 604.7   5 270.4 1.1409 94.0, 1581.0 2.85
BXD100 m 57.67 38.734   3 22.363 0.6717 24.0, 100.0 -0.77
BXD101 m 256.8 34.97   4 17.485 0.1362 222.0, 299.0 0.75
BXD12 m 305.8 303.3   5 135.6 0.9919 83.0, 824.0 1.13
BXD16 m 79.5 24.447   4 12.224 0.3075 57.0, 112.0 -0.6
BXD27 m 96.2 39.073   5 17.474 0.4062 53.0, 150.0 -0.48
BXD32 m 160.8 211.4   5 94.56 1.315 33.0, 534.0 0.02
BXD34 m 55.0 6.6833   4 3.3417 0.1215 49.0, 64.0 -0.79
BXD39 m 181.2 190.5   5 85.18 1.0511 64.0, 519.0 0.17
BXD40 m 308.7 338.0   3 195.2 1.0952 113.0, 699.0 1.15
BXD43 m 122.3 12.503   3 7.2188 0.1022 108.0, 131.0 -0.28
BXD44 m 78.0 49.092   7 18.555 0.6294 17.0, 157.0 -0.62
BXD45 m 509.6 703.1   5 314.4 1.3797 77.0, 1736.0 2.69
BXD48 m 88.0 68.17   5 30.484 0.7746 41.0, 206.0 -0.54
BXD48a m 137.8 115.9   5 51.85 0.8414 12.0, 314.0 -0.16
BXD49 m 62.5 17.483   4 8.7417 0.2797 49.0, 88.0 -0.74
BXD50 m 56.5 19.399   4 9.6997 0.3434 33.0, 80.0 -0.78
BXD51 m 10.667 7.5056   3 4.3333 0.7036 3.0, 18.0 -1.13
BXD53 m 125.5 108.3   4 54.16 0.8631 50.0, 286.0 -0.25
BXD55 m 114.2 142.0   5 63.48 1.243 18.0, 359.0 -0.34
BXD56 m 147.7 121.3   3 70.05 0.8217 55.0, 285.0 -0.08
BXD6 m 123.5 104.6   4 52.32 0.8473 57.0, 279.0 -0.27
BXD60 m 186.5 85.25   4 42.623 0.4571 89.0, 288.0 0.21
BXD61 m 30.0 8.7178   3 5.0332 0.2906 20.0, 36.0 -0.98
BXD62 m 171.5 92.27   4 46.135 0.538 64.0, 287.0 0.1
BXD63 m 92.33 14.012   3 8.0898 0.1518 81.0, 108.0 -0.51
BXD64 m 57.33 17.388   3 10.039 0.3033 44.0, 77.0 -0.77
BXD65 m 201.5 150.9   4 75.43 0.7487 76.0, 402.0 0.33
BXD65a m 90.6 23.87   5 10.675 0.2635 64.0, 129.0 -0.52
BXD65b m 327.5 280.9   4 140.4 0.8577 49.0, 617.0 1.29
BXD66 m 112.8 65.37   5 29.234 0.5795 33.0, 215.0 -0.35
BXD67 m 79.5 30.73   4 15.365 0.3865 44.0, 119.0 -0.6
BXD68 m 339.0 393.5   3 227.2 1.1607 73.0, 791.0 1.38
BXD69 m 157.0 136.0   5 60.81 0.866 65.0, 391.0 -0.01
BXD70 m 62.75 51.97   4 25.985 0.8282 14.0, 136.0 -0.73
BXD71 m 130.0 61.36   4 30.681 0.472 78.0, 210.0 -0.22
BXD73 m 66.25 65.3   4 32.651 0.9857 3.0, 150.0 -0.71
BXD73a m 34.2 20.511   5 9.1728 0.5997 16.0, 67.0 -0.95
BXD73b m 273.4 206.0   5 92.14 0.7536 81.0, 606.0 0.88
BXD75 m 123.2 157.9   5 70.63 1.282 13.0, 401.0 -0.27
BXD77 m 239.8 186.9   4 93.47 0.7797 56.0, 415.0 0.62
BXD79 m 158.6 86.1   5 38.505 0.5429 59.0, 261.0 0.0
BXD81 m 181.8 153.2   4 76.62 0.8431 54.0, 382.0 0.18
BXD83 m 145.7 102.7   3 59.31 0.7053 35.0, 238.0 -0.1
BXD84 m 112.7 62.07   3 35.834 0.5509 56.0, 179.0 -0.35
BXD85 m 179.2 144.2   5 64.47 0.8045 81.0, 422.0 0.16
BXD87 m 207.2 280.0   5 125.2 1.3515 62.0, 707.0 0.37
BXD89 m 684.0 478.1   4 239.1 0.699 95.0, 1225.0 4.03
BXD90 m 37.0 10.231   4 5.1153 0.2765 23.0, 46.0 -0.93
BXD95 m 101.5 62.58   4 31.29 0.6166 38.0, 185.0 -0.44
BXD98 m 62.67 13.204   3 7.6231 0.2107 51.0, 77.0 -0.73
BXD99 m 173.6 76.22   5 34.086 0.439 115.0, 300.0 0.12
C57BL/6J m 126.5 89.81   4 44.905 0.71 60.0, 259.0 -0.24
DBA/2J m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -1.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 530.0 91.5439378883 710.716928742 349.283071258
BXD100 m 57.6666666667 118.1827156293 290.9712184652 -175.6378851319
BXD101 m 256.75 102.3492340232 458.7976686761 54.7023313239
BXD12 m 305.8 91.5439378883 486.516928742 125.083071258
BXD16 m 79.5 102.3492340232 281.5476686761 -122.5476686761
BXD27 m 96.2 91.5439378883 276.916928742 -84.516928742
BXD32 m 160.8 91.5439378883 341.516928742 -19.916928742
BXD34 m 55.0 102.3492340232 257.0476686761 -147.0476686761
BXD39 m 181.2 91.5439378883 361.916928742 0.483071258
BXD40 m 308.6666666667 118.1827156293 541.9712184652 75.3621148681
BXD43 m 122.3333333333 118.1827156292 355.6378851319 -110.9712184652
BXD44 m 78.0 77.3687486009 230.7336812278 -74.7336812278
BXD45 m 509.6 91.5439378883 690.316928742 328.883071258
BXD48 m 88.0 91.5439378883 268.716928742 -92.716928742
BXD48a m 137.8 91.5439378883 318.516928742 -42.916928742
BXD49 m 62.5 102.3492340232 264.5476686761 -139.5476686761
BXD50 m 56.5 102.3492340232 258.5476686761 -145.5476686761
BXD51 m 10.6666666667 118.1827156293 243.9712184652 -222.6378851319
BXD53 m 125.5 102.3492340232 327.5476686761 -76.5476686761
BXD55 m 114.2 91.5439378883 294.916928742 -66.516928742
BXD56 m 147.6666666667 118.1827156293 380.9712184652 -85.6378851319
BXD6 m 123.5 102.3492340232 325.5476686761 -78.5476686761
BXD60 m 186.5 102.3492340232 388.5476686761 -15.5476686761
BXD61 m 30.0 118.1827156293 263.3045517985 -203.3045517985
BXD62 m 171.5 102.3492340232 373.5476686761 -30.5476686761
BXD63 m 92.3333333333 118.1827156293 325.6378851319 -140.9712184652
BXD64 m 57.3333333333 118.1827156293 290.6378851319 -175.9712184652
BXD65 m 201.5 102.3492340232 403.5476686761 -0.5476686761
BXD65a m 90.6 91.5439378883 271.316928742 -90.116928742
BXD65b m 327.5 102.3492340232 529.5476686761 125.4523313239
BXD66 m 112.8 91.5439378883 293.516928742 -67.916928742
BXD67 m 79.5 102.3492340232 281.5476686761 -122.5476686761
BXD68 m 339.0 118.1827156293 572.3045517985 105.6954482015
BXD69 m 157.0 91.5439378883 337.716928742 -23.716928742
BXD70 m 62.75 102.3492340232 264.7976686761 -139.2976686761
BXD71 m 130.0 102.3492340232 332.0476686761 -72.0476686761
BXD73 m 66.25 102.3492340232 268.2976686761 -135.7976686761
BXD73a m 34.2 91.5439378883 214.916928742 -146.516928742
BXD73b m 273.4 91.5439378883 454.116928742 92.683071258
BXD75 m 123.2 91.5439378883 303.916928742 -57.516928742
BXD77 m 239.75 102.3492340232 441.7976686761 37.7023313239
BXD79 m 158.6 91.5439378883 339.316928742 -22.116928742
BXD81 m 181.75 102.3492340232 383.7976686761 -20.2976686761
BXD83 m 145.6666666667 118.1827156293 378.9712184652 -87.6378851319
BXD84 m 112.6666666667 118.1827156293 345.9712184652 -120.6378851319
BXD85 m 179.2 91.5439378883 359.916928742 -1.516928742
BXD87 m 207.2 91.5439378883 387.916928742 26.483071258
BXD89 m 684.0 102.3492340232 886.0476686761 481.9523313239
BXD90 m 37.0 102.3492340232 239.0476686761 -165.0476686761
BXD95 m 101.5 102.3492340232 303.5476686761 -100.5476686761
BXD98 m 62.6666666667 118.1827156293 295.9712184652 -170.6378851319
BXD99 m 173.6 91.5439378883 354.316928742 -7.116928742
C57BL/6J m 126.5 102.3492340232 328.5476686761 -75.5476686761




  GWAS USING LINEAR MIXED MODELS