Project measure / variable:   Auwerx1   bile_HFD

ID, description, units MPD:111349   bile_HFD   blood bile acid amount   [µmol/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   33 strains     sex: m     age: 29wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx1 - blood bile acid amount HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested33 strains
Mean of the strain means23.049   µmol/L
Median of the strain means12.0   µmol/L
SD of the strain means± 49.738
Coefficient of variation (CV)2.1579
Min–max range of strain means0.1   –   289.9   µmol/L
Mean sample size per strain3.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 26 310837.9607 11955.3062 3.61 < 0.0001
Residuals 76 251693.1645 3311.7522


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.5 0.0   1   0.0 0.0 0.5, 0.5 -0.45
BXD100 m 5.8 6.2698   3 3.6199 1.081 0.7, 12.8 -0.35
BXD101 m 3.55 1.5546   4 0.77728 0.4379 1.3, 4.8 -0.39
BXD16 m 6.32 2.6621   5 1.1905 0.4212 3.1, 8.7 -0.34
BXD27 m 3.75 0.99833   4 0.49917 0.2662 2.7, 4.7 -0.39
BXD32 m 0.1 0.0   1   0.0 0.0 0.1, 0.1 -0.46
BXD34 m 1.7 0.5831   5 0.26077 0.343 1.1, 2.5 -0.43
BXD39 m 30.78 53.05   5 23.726 1.7236 2.3, 125.5 0.16
BXD40 m 1.925 0.5058   4 0.2529 0.2628 1.3, 2.5 -0.42
BXD44 m 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.22
BXD48a m 27.733 3.7072   3 2.1404 0.1337 23.5, 30.4 0.09
BXD50 m 3.22 1.874   5 0.83809 0.582 1.4, 6.2 -0.4
BXD53 m 23.72 33.343   5 14.911 1.4057 6.7, 83.3 0.01
BXD55 m 13.133 5.8518   3 3.3785 0.4456 7.2, 18.9 -0.2
BXD6 m 6.24 3.9929   5 1.7857 0.6399 2.4, 12.2 -0.34
BXD60 m 19.925 20.346   4 10.173 1.0211 4.1, 49.7 -0.06
BXD61 m 289.9 276.1   4 138.1 0.9524 27.1, 670.4 5.37
BXD62 m 24.3 20.789   2   14.7 0.8555 9.6, 39.0 0.03
BXD63 m 33.0 0.0   1   0.0 0.0 33.0, 33.0 0.2
BXD65a m 8.525 8.1028   4 4.0514 0.9505 1.9, 20.1 -0.29
BXD66 m 40.925 3.7482   4 1.8741 0.0916 36.3, 45.2 0.36
BXD67 m 6.52 3.9201   5 1.7531 0.6012 2.1, 12.8 -0.33
BXD70 m 22.2 0.0   1   0.0 0.0 22.2, 22.2 -0.02
BXD73 m 51.27 40.531   3 23.4 0.7906 4.7, 78.6 0.57
BXD73a m 13.7 0.0   1   0.0 0.0 13.7, 13.7 -0.19
BXD75 m 20.55 16.617   2   11.75 0.8086 8.8, 32.3 -0.05
BXD77 m 0.76 0.15166   5 0.06782 0.1995 0.5, 0.9 -0.45
BXD79 m 16.98 13.953   5 6.2399 0.8217 4.4, 36.0 -0.12
BXD83 m 41.45 18.738   2   13.25 0.4521 28.2, 54.7 0.37
BXD90 m 12.65 8.556   2   6.05 0.6764 6.6, 18.7 -0.21
BXD95 m 1.1 0.63246   4 0.31623 0.575 0.5, 1.9 -0.44
C57BL/6J m 7.4 8.9095   2   6.3 1.204 1.1, 13.7 -0.31
DBA/2J m 9.0 6.5182   4 3.2591 0.7242 1.5, 17.3 -0.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD100 m 5.8 33.2252522663 71.9738248873 -60.3738248873
BXD101 m 3.55 28.7739125097 60.858213418 -53.758213418
BXD16 m 6.32 25.7361697402 57.5780243487 -44.9380243487
BXD27 m 3.75 28.7739125097 61.058213418 -53.558213418
BXD34 m 1.7 25.7361697402 52.9580243487 -49.5580243487
BXD39 m 30.78 25.7361697402 82.0380243487 -20.4780243487
BXD40 m 1.925 28.7739125097 59.233213418 -55.383213418
BXD48a m 27.7333333333 33.2252522663 93.9071582206 -38.4404915539
BXD50 m 3.22 25.7361697402 54.4780243487 -48.0380243487
BXD53 m 23.72 25.7361697402 74.9780243487 -27.5380243487
BXD55 m 13.1333333333 33.2252522663 79.3071582206 -53.0404915539
BXD6 m 6.24 25.7361697402 57.4980243487 -45.0180243487
BXD60 m 19.925 28.7739125097 77.233213418 -37.383213418
BXD61 m 289.925 28.7739125097 347.233213418 232.616786582
BXD62 m 24.3 40.6924573138 105.3460526511 -56.7460526511
BXD65a m 8.525 28.7739125097 65.833213418 -48.783213418
BXD66 m 40.925 28.7739125097 98.233213418 -16.383213418
BXD67 m 6.52 25.7361697402 57.7780243487 -44.7380243487
BXD73 m 51.2666666667 33.2252522663 117.4404915539 -14.9071582206
BXD75 m 20.55 40.6924573138 101.5960526511 -60.4960526511
BXD77 m 0.76 25.7361697402 52.0180243487 -50.4980243487
BXD79 m 16.98 25.7361697402 68.2380243487 -34.2780243487
BXD83 m 41.45 40.6924573138 122.4960526511 -39.5960526511
BXD90 m 12.65 40.6924573138 93.6960526511 -68.3960526511
BXD95 m 1.1 28.7739125097 58.408213418 -56.208213418
C57BL/6J m 7.4 40.6924573138 88.4460526511 -73.6460526511
DBA/2J m 9.0 28.7739125097 66.308213418 -48.308213418




  GWAS USING LINEAR MIXED MODELS