Project measure / variable:   Auwerx1   bile_CD

ID, description, units MPD:111348   bile_CD   blood bile acid amount   [µmol/L]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   32 strains     sex: m     age: 29wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx1 - blood bile acid amount CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested32 strains
Mean of the strain means17.683   µmol/L
Median of the strain means7.0666   µmol/L
SD of the strain means± 32.355
Coefficient of variation (CV)1.8297
Min–max range of strain means0.25   –   174.6   µmol/L
Mean sample size per strain3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 29 99473.2132 3430.1108 1.8769 0.0152
Residuals 77 140720.6137 1827.5404


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.25 0.21213   2   0.15 0.8485 0.1, 0.4 -0.54
BXD100 m 15.7 6.9296   2   4.9 0.4414 10.8, 20.6 -0.06
BXD12 m 4.6 2.0408   5 0.91269 0.4437 2.6, 7.8 -0.4
BXD16 m 5.45 3.5651   4 1.7826 0.6541 2.7, 10.5 -0.38
BXD27 m 5.1 3.3867   5 1.5146 0.6641 2.3, 9.8 -0.39
BXD32 m 1.14 0.66558   5 0.29766 0.5838 0.5, 2.2 -0.51
BXD34 m 2.125 0.4272   4 0.2136 0.201 1.6, 2.6 -0.48
BXD39 m 4.24 2.6969   5 1.2061 0.636 2.3, 9.0 -0.42
BXD40 m 4.5667 3.4933   3 2.0169 0.765 2.5, 8.6 -0.41
BXD44 m 30.325 24.622   4 12.311 0.812 8.8, 58.1 0.39
BXD45 m 9.75 4.3134   2   3.05 0.4424 6.7, 12.8 -0.25
BXD48a m 16.3 6.6468   2   4.7 0.4078 11.6, 21.0 -0.04
BXD51 m 8.6 1.9799   2   1.4 0.2302 7.2, 10.0 -0.28
BXD53 m 17.775 27.091   4 13.546 1.5241 3.5, 58.4 0.0
BXD55 m 4.5 0.84853   2   0.6 0.1886 3.9, 5.1 -0.41
BXD6 m 5.3 1.4629   4 0.73144 0.276 3.9, 6.8 -0.38
BXD62 m 29.9 16.936   4 8.4679 0.5664 11.4, 51.0 0.38
BXD63 m 174.6 247.8   3 143.1 1.4193 28.3, 460.8 4.85
BXD65a m 5.42 8.5917   5 3.8423 1.5852 0.1, 20.6 -0.38
BXD66 m 31.24 5.5595   5 2.4863 0.178 25.3, 39.6 0.42
BXD67 m 3.75 1.3675   4 0.68374 0.3647 1.7, 4.5 -0.43
BXD70 m 13.7 0.0   1   0.0 0.0 13.7, 13.7 -0.12
BXD73 m 5.5333 4.5654   3 2.6359 0.8251 2.7, 10.8 -0.38
BXD73a m 80.5 75.94   3 43.847 0.9434 3.1, 154.9 1.94
BXD75 m 12.3 4.6508   3 2.6851 0.3781 7.6, 16.9 -0.17
BXD77 m 2.275 0.75   4 0.375 0.3297 1.5, 3.1 -0.48
BXD79 m 11.18 9.92   5 4.4364 0.8873 3.7, 27.1 -0.2
BXD83 m 19.65 7.4246   2   5.25 0.3778 14.4, 24.9 0.06
BXD87 m 1.1 0.0   1   0.0 0.0 1.1, 1.1 -0.51
BXD89 m 14.2 7.231   4 3.6155 0.5092 6.2, 22.0 -0.11
BXD90 m 19.35 3.2685   4 1.6343 0.1689 15.5, 22.4 0.05
DBA/2J m 5.4333 3.086   3 1.7817 0.568 1.9, 7.6 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.25 30.2286324304 60.4428971937 -59.9428971937
BXD100 m 15.7 30.2286324304 75.8928971937 -44.4928971937
BXD12 m 4.6 19.1182658064 42.6693308193 -33.4693308193
BXD16 m 5.45 21.3748709776 48.0128057849 -37.1128057849
BXD27 m 5.1 19.1182658064 43.1693308193 -32.9693308193
BXD32 m 1.14 19.1182658064 39.2093308193 -36.9293308193
BXD34 m 2.125 21.3748709776 44.6878057849 -40.4378057849
BXD39 m 4.24 19.1182658064 42.3093308193 -33.8293308193
BXD40 m 4.5666666667 24.6815750256 53.7139614215 -44.5806280881
BXD44 m 30.325 21.3748709776 72.8878057849 -12.2378057849
BXD45 m 9.75 30.2286324304 69.9428971937 -50.4428971937
BXD48a m 16.3 30.2286324304 76.4928971937 -43.8928971937
BXD51 m 8.6 30.2286324304 68.7928971937 -51.5928971937
BXD53 m 17.775 21.3748709776 60.3378057849 -24.7878057849
BXD55 m 4.5 30.2286324304 64.6928971937 -55.6928971937
BXD6 m 5.3 21.3748709776 47.8628057849 -37.2628057849
BXD62 m 29.9 21.3748709776 72.4628057849 -12.6628057849
BXD63 m 174.6333333333 24.6815750256 223.7806280881 125.4860385785
BXD65a m 5.42 19.1182658064 43.4893308193 -32.6493308193
BXD66 m 31.24 19.1182658064 69.3093308193 -6.8293308193
BXD67 m 3.75 21.3748709776 46.3128057849 -38.8128057849
BXD73 m 5.5333333333 24.6815750256 54.6806280881 -43.6139614215
BXD73a m 80.5 24.6815750256 129.6472947548 31.3527052452
BXD75 m 12.3 24.6815750256 61.4472947548 -36.8472947548
BXD77 m 2.275 21.3748709776 44.8378057849 -40.2878057849
BXD79 m 11.18 19.1182658064 49.2493308193 -26.8893308193
BXD83 m 19.65 30.2286324304 79.8428971937 -40.5428971937
BXD89 m 14.2 21.3748709776 56.7628057849 -28.3628057849
BXD90 m 19.35 21.3748709776 61.9128057849 -23.2128057849
DBA/2J m 5.4333333333 24.6815750256 54.5806280881 -43.7139614215




  GWAS USING LINEAR MIXED MODELS