Project measure / variable:   Auwerx1   asp_trans_HFD

ID, description, units MPD:111347   asp_trans_HFD   blood aspartate transaminase amount   [U/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   52 strains     sex: m     age: 29wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx1 - blood aspartate transaminase amount HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested52 strains
Mean of the strain means135.8   U/L
Median of the strain means113.0   U/L
SD of the strain means± 98.52
Coefficient of variation (CV)0.7255
Min–max range of strain means23.8   –   496.0   U/L
Mean sample size per strain4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 51 2098831.0876 41153.5507 7.9783 < 0.0001
Residuals 163 840781.0333 5158.1658


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 45.0 9.0   5 4.0249 0.2 30.0, 54.0 -0.92
BXD100 m 52.4 12.361   5 5.5281 0.2359 38.0, 64.0 -0.85
BXD101 m 281.0 119.4   4 59.68 0.4247 113.0, 387.0 1.47
BXD16 m 88.6 29.211   5 13.064 0.3297 47.0, 128.0 -0.48
BXD27 m 123.0 41.028   4 20.514 0.3336 70.0, 161.0 -0.13
BXD32 m 55.33 13.796   3 7.9652 0.2493 45.0, 71.0 -0.82
BXD34 m 23.8 10.569   5 4.7265 0.4441 15.0, 40.0 -1.14
BXD39 m 397.0 138.3   4 69.13 0.3483 252.0, 532.0 2.65
BXD40 m 42.75 18.786   4 9.393 0.4394 27.0, 70.0 -0.94
BXD43 m 73.33 24.42   3 14.099 0.333 46.0, 93.0 -0.63
BXD44 m 122.4 83.96   5 37.549 0.686 35.0, 249.0 -0.14
BXD45 m 30.0 33.744   4 16.872 1.1248 6.0, 80.0 -1.07
BXD48 m 113.4 30.746   5 13.75 0.2711 61.0, 141.0 -0.23
BXD48a m 156.0 61.99   3 35.791 0.3974 87.0, 207.0 0.21
BXD49 m 129.5 37.171   4 18.585 0.287 108.0, 185.0 -0.06
BXD50 m 157.0 82.06   5 36.697 0.5227 95.0, 295.0 0.22
BXD51 m 119.2 40.153   4 20.076 0.3367 86.0, 171.0 -0.17
BXD53 m 287.2 239.8   4 119.9 0.835 165.0, 647.0 1.54
BXD55 m 73.0 20.083   4 10.042 0.2751 54.0, 101.0 -0.64
BXD56 m 94.0 12.728   2   9.0 0.1354 85.0, 103.0 -0.42
BXD6 m 65.0 15.969   5 7.1414 0.2457 48.0, 86.0 -0.72
BXD60 m 353.5 84.15   2   59.5 0.238 294.0, 413.0 2.21
BXD61 m 348.8 145.6   5 65.14 0.4176 184.0, 558.0 2.16
BXD62 m 80.25 59.13   4 29.565 0.7368 33.0, 166.0 -0.56
BXD63 m 141.0 131.5   2   93.0 0.9328 48.0, 234.0 0.05
BXD64 m 191.0 85.65   4 42.825 0.4484 111.0, 291.0 0.56
BXD65 m 247.2 70.68   4 35.342 0.2859 173.0, 337.0 1.13
BXD65a m 162.8 52.18   4 26.088 0.3206 102.0, 212.0 0.27
BXD66 m 77.5 17.823   4 8.9116 0.23 63.0, 103.0 -0.59
BXD67 m 247.4 214.0   5 95.71 0.8651 85.0, 620.0 1.13
BXD68 m 123.5 25.645   4 12.823 0.2077 92.0, 149.0 -0.12
BXD69 m 191.6 48.814   5 21.83 0.2548 158.0, 278.0 0.57
BXD70 m 45.333 19.296   3 11.141 0.4256 30.0, 67.0 -0.92
BXD71 m 156.0 55.05   3 31.786 0.3529 106.0, 215.0 0.21
BXD73 m 93.0 17.282   4 8.641 0.1858 69.0, 109.0 -0.43
BXD73a m 90.4 13.939   5 6.2338 0.1542 78.0, 107.0 -0.46
BXD73b m 105.4 23.734   5 10.614 0.2252 71.0, 134.0 -0.31
BXD75 m 117.6 62.82   5 28.094 0.5342 60.0, 214.0 -0.18
BXD77 m 103.6 54.12   5 24.205 0.5224 32.0, 150.0 -0.33
BXD79 m 134.0 42.065   5 18.812 0.3139 85.0, 190.0 -0.02
BXD81 m 133.0 31.512   3 18.193 0.2369 102.0, 165.0 -0.03
BXD83 m 73.0 22.642   4 11.321 0.3102 46.0, 101.0 -0.64
BXD84 m 121.7 27.154   3 15.677 0.2232 105.0, 153.0 -0.14
BXD85 m 112.5 18.699   4 9.3497 0.1662 96.0, 132.0 -0.24
BXD87 m 94.6 58.86   5 26.322 0.6222 33.0, 177.0 -0.42
BXD89 m 103.2 59.28   4 29.641 0.5742 61.0, 190.0 -0.33
BXD90 m 30.667 18.583   3 10.729 0.606 10.0, 46.0 -1.07
BXD95 m 159.8 55.14   4 27.572 0.3452 89.0, 211.0 0.24
BXD98 m 496.0 71.84   5 32.128 0.1448 407.0, 588.0 3.66
BXD99 m 79.0 23.885   5 10.682 0.3023 47.0, 104.0 -0.58
C57BL/6J m 68.6 35.43   5 15.845 0.5165 32.0, 127.0 -0.68
DBA/2J m 50.4 6.4265   5 2.874 0.1275 39.0, 54.0 -0.87


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 45.0 32.1190468373 108.4230606868 -18.4230606868
BXD100 m 52.4 32.1190468373 115.8230606868 -11.0230606868
BXD101 m 281.0 35.9101860503 351.9091375184 210.0908624816
BXD16 m 88.6 32.1190468373 152.0230606868 25.1769393132
BXD27 m 123.0 35.9101860503 193.9091375184 52.0908624816
BXD32 m 55.3333333333 41.4655111656 137.2121526019 -26.5454859352
BXD34 m 23.8 32.1190468373 87.2230606868 -39.6230606868
BXD39 m 397.0 35.9101860503 467.9091375184 326.0908624816
BXD40 m 42.75 35.9101860503 113.6591375184 -28.1591375184
BXD43 m 73.3333333333 41.4655111656 155.2121526019 -8.5454859352
BXD44 m 122.4 32.1190468373 185.8230606868 58.9769393132
BXD45 m 30.0 35.9101860503 100.9091375184 -40.9091375184
BXD48 m 113.4 32.1190468373 176.8230606868 49.9769393132
BXD48a m 156.0 41.4655111656 237.8788192685 74.1211807315
BXD49 m 129.5 35.9101860503 200.4091375184 58.5908624816
BXD50 m 157.0 32.1190468373 220.4230606868 93.5769393132
BXD51 m 119.25 35.9101860503 190.1591375184 48.3408624816
BXD53 m 287.25 35.9101860503 358.1591375184 216.3408624816
BXD55 m 73.0 35.9101860503 143.9091375184 2.0908624816
BXD56 m 94.0 50.7846721397 194.2806639747 -6.2806639747
BXD6 m 65.0 32.1190468373 128.4230606868 1.5769393132
BXD60 m 353.5 50.7846721397 453.7806639747 253.2193360253
BXD61 m 348.8 32.1190468373 412.2230606868 285.3769393132
BXD62 m 80.25 35.9101860503 151.1591375184 9.3408624816
BXD63 m 141.0 50.7846721397 241.2806639747 40.7193360253
BXD64 m 191.0 35.9101860503 261.9091375184 120.0908624816
BXD65 m 247.25 35.9101860503 318.1591375184 176.3408624816
BXD65a m 162.75 35.9101860503 233.6591375184 91.8408624816
BXD66 m 77.5 35.9101860503 148.4091375184 6.5908624816
BXD67 m 247.4 32.1190468373 310.8230606868 183.9769393132
BXD68 m 123.5 35.9101860503 194.4091375184 52.5908624816
BXD69 m 191.6 32.1190468373 255.0230606868 128.1769393132
BXD70 m 45.3333333333 41.4655111656 127.2121526019 -36.5454859352
BXD71 m 156.0 41.4655111656 237.8788192685 74.1211807315
BXD73 m 93.0 35.9101860503 163.9091375184 22.0908624816
BXD73a m 90.4 32.1190468373 153.8230606868 26.9769393132
BXD73b m 105.4 32.1190468373 168.8230606868 41.9769393132
BXD75 m 117.6 32.1190468373 181.0230606868 54.1769393132
BXD77 m 103.6 32.1190468373 167.0230606868 40.1769393132
BXD79 m 134.0 32.1190468373 197.4230606868 70.5769393132
BXD81 m 133.0 41.4655111656 214.8788192685 51.1211807315
BXD83 m 73.0 35.9101860503 143.9091375184 2.0908624816
BXD84 m 121.6666666667 41.4655111656 203.5454859352 39.7878473981
BXD85 m 112.5 35.9101860503 183.4091375184 41.5908624816
BXD87 m 94.6 32.1190468373 158.0230606868 31.1769393132
BXD89 m 103.25 35.9101860503 174.1591375184 32.3408624816
BXD90 m 30.6666666667 41.4655111656 112.5454859352 -51.2121526019
BXD95 m 159.75 35.9101860503 230.6591375184 88.8408624816
BXD98 m 496.0 32.1190468373 559.4230606868 432.5769393132
BXD99 m 79.0 32.1190468373 142.4230606868 15.5769393132
C57BL/6J m 68.6 32.1190468373 132.0230606868 5.1769393132
DBA/2J m 50.4 32.1190468373 113.8230606868 -13.0230606868




  GWAS USING LINEAR MIXED MODELS