Project measure / variable:   Auwerx1   alk_phosph_HFD

ID, description, units MPD:111343   alk_phosph_HFD   blood alkaline phosphatase amount   [U/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   52 strains     sex: m     age: 29wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx1 - blood alkaline phosphatase amount HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested52 strains
Mean of the strain means85.05   U/L
Median of the strain means78.7   U/L
SD of the strain means± 29.83
Coefficient of variation (CV)0.3507
Min–max range of strain means40.2   –   161.4   U/L
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 51 182317.0429 3574.844 9.7942 < 0.0001
Residuals 165 60224.1 364.9945


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 70.2 30.589   5 13.68 0.4357 17.0, 95.0 -0.5
BXD100 m 68.0 13.285   5 5.9414 0.1954 49.0, 86.0 -0.57
BXD101 m 79.75 6.9462   4 3.4731 0.0871 72.0, 87.0 -0.18
BXD16 m 106.4 20.983   5 9.384 0.1972 83.0, 131.0 0.72
BXD27 m 74.0 18.421   4 9.2105 0.2489 57.0, 99.0 -0.37
BXD32 m 51.33 6.5064   3 3.7565 0.1267 45.0, 58.0 -1.13
BXD34 m 42.8 4.4385   5 1.9849 0.1037 39.0, 50.0 -1.42
BXD39 m 92.2 12.755   5 5.7044 0.1383 78.0, 105.0 0.24
BXD40 m 89.25 11.871   4 5.9354 0.133 78.0, 100.0 0.14
BXD43 m 79.0 16.093   3 9.2916 0.2037 66.0, 97.0 -0.2
BXD44 m 76.2 7.791   5 3.4843 0.1022 67.0, 86.0 -0.3
BXD45 m 83.25 4.5735   4 2.2867 0.0549 80.0, 90.0 -0.06
BXD48 m 71.8 8.4083   5 3.7603 0.1171 62.0, 83.0 -0.44
BXD48a m 73.67 11.15   3 6.4377 0.1514 61.0, 82.0 -0.38
BXD49 m 97.5 40.583   4 20.292 0.4162 71.0, 158.0 0.42
BXD50 m 69.6 9.685   5 4.3313 0.1392 59.0, 85.0 -0.52
BXD51 m 117.2 16.235   4 8.1176 0.1385 102.0, 138.0 1.08
BXD53 m 116.2 44.099   5 19.722 0.3795 81.0, 188.0 1.04
BXD55 m 66.5 17.098   4 8.5489 0.2571 43.0, 84.0 -0.62
BXD56 m 59.5 4.9497   2   3.5 0.0832 56.0, 63.0 -0.86
BXD6 m 40.2 3.4928   5 1.562 0.0869 38.0, 46.0 -1.5
BXD60 m 150.2 21.5   4 10.75 0.1431 131.0, 179.0 2.18
BXD61 m 132.5 14.849   2   10.5 0.1121 122.0, 143.0 1.59
BXD62 m 50.5 13.478   4 6.7392 0.2669 31.0, 60.0 -1.16
BXD63 m 51.0 4.2426   2   3.0 0.0832 48.0, 54.0 -1.14
BXD64 m 124.8 25.277   4 12.638 0.2026 98.0, 151.0 1.33
BXD65 m 115.0 9.4163   4 4.7081 0.0819 106.0, 125.0 1.0
BXD65a m 95.25 14.546   4 7.273 0.1527 74.0, 106.0 0.34
BXD66 m 61.5 5.5076   4 2.7538 0.0896 56.0, 68.0 -0.79
BXD67 m 66.6 13.334   5 5.9632 0.2002 52.0, 86.0 -0.62
BXD68 m 54.25 7.1822   4 3.5911 0.1324 45.0, 62.0 -1.03
BXD69 m 119.8 33.071   5 14.79 0.2761 94.0, 176.0 1.16
BXD70 m 104.3 30.288   3 17.487 0.2903 83.0, 139.0 0.65
BXD71 m 122.3 57.49   3 33.193 0.47 77.0, 187.0 1.25
BXD73 m 45.75 2.63   4 1.315 0.0575 42.0, 48.0 -1.32
BXD73a m 56.6 16.727   5 7.4806 0.2955 32.0, 76.0 -0.95
BXD73b m 59.0 4.0   5 1.7889 0.0678 54.0, 64.0 -0.87
BXD75 m 68.0 11.18   5 5.0 0.1644 60.0, 87.0 -0.57
BXD77 m 78.4 9.0995   5 4.0694 0.1161 66.0, 91.0 -0.22
BXD79 m 122.0 25.768   5 11.524 0.2112 99.0, 165.0 1.24
BXD81 m 160.7 22.368   3 12.914 0.1392 135.0, 176.0 2.54
BXD83 m 82.5 25.671   4 12.835 0.3112 60.0, 116.0 -0.09
BXD84 m 58.67 1.1547   3 0.66667 0.0197 58.0, 60.0 -0.88
BXD85 m 96.0 19.476   4 9.7382 0.2029 79.0, 124.0 0.37
BXD87 m 62.8 10.035   5 4.4878 0.1598 52.0, 72.0 -0.75
BXD89 m 81.5 7.1414   4 3.5707 0.0876 76.0, 92.0 -0.12
BXD90 m 96.75 9.0692   4 4.5346 0.0937 88.0, 108.0 0.39
BXD95 m 103.0 18.673   4 9.3363 0.1813 80.0, 121.0 0.6
BXD98 m 161.4 31.832   5 14.236 0.1972 117.0, 197.0 2.56
BXD99 m 93.2 13.368   5 5.9783 0.1434 79.0, 115.0 0.27
C57BL/6J m 61.6 16.817   5 7.5206 0.273 37.0, 81.0 -0.79
DBA/2J m 62.4 5.0299   5 2.2494 0.0806 57.0, 70.0 -0.76


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 70.2 8.5439399045 87.0695448081 53.3304551919
BXD100 m 68.0 8.5439399045 84.8695448081 51.1304551919
BXD101 m 79.75 9.552415211 98.6107244702 60.8892755298
BXD16 m 106.4 8.5439399045 123.2695448081 89.5304551919
BXD27 m 74.0 9.552415211 92.8607244702 55.1392755298
BXD32 m 51.3333333333 11.030178987 73.1118220333 29.5548446334
BXD34 m 42.8 8.5439399045 59.6695448081 25.9304551919
BXD39 m 92.2 8.5439399045 109.0695448081 75.3304551919
BXD40 m 89.25 9.552415211 108.1107244702 70.3892755298
BXD43 m 79.0 11.030178987 100.7784887 57.2215113
BXD44 m 76.2 8.5439399045 93.0695448081 59.3304551919
BXD45 m 83.25 9.552415211 102.1107244702 64.3892755298
BXD48 m 71.8 8.5439399045 88.6695448081 54.9304551919
BXD48a m 73.6666666667 11.030178987 95.4451553666 51.8881779667
BXD49 m 97.5 9.552415211 116.3607244702 78.6392755298
BXD50 m 69.6 8.5439399045 86.4695448081 52.7304551919
BXD51 m 117.25 9.552415211 136.1107244702 98.3892755298
BXD53 m 116.2 8.5439399045 133.0695448081 99.3304551919
BXD55 m 66.5 9.552415211 85.3607244702 47.6392755298
BXD56 m 59.5 13.5091551448 86.173092342 32.826907658
BXD6 m 40.2 8.5439399045 57.0695448081 23.3304551919
BXD60 m 150.25 9.552415211 169.1107244702 131.3892755298
BXD61 m 132.5 13.5091551448 159.173092342 105.826907658
BXD62 m 50.5 9.552415211 69.3607244702 31.6392755298
BXD63 m 51.0 13.5091551448 77.673092342 24.326907658
BXD64 m 124.75 9.552415211 143.6107244702 105.8892755298
BXD65 m 115.0 9.552415211 133.8607244702 96.1392755298
BXD65a m 95.25 9.552415211 114.1107244702 76.3892755298
BXD66 m 61.5 9.552415211 80.3607244702 42.6392755298
BXD67 m 66.6 8.5439399045 83.4695448081 49.7304551919
BXD68 m 54.25 9.552415211 73.1107244702 35.3892755298
BXD69 m 119.8 8.5439399045 136.6695448081 102.9304551919
BXD70 m 104.3333333333 11.030178987 126.1118220333 82.5548446334
BXD71 m 122.3333333333 11.030178987 144.1118220333 100.5548446334
BXD73 m 45.75 9.552415211 64.6107244702 26.8892755298
BXD73a m 56.6 8.5439399045 73.4695448081 39.7304551919
BXD73b m 59.0 8.5439399045 75.8695448081 42.1304551919
BXD75 m 68.0 8.5439399045 84.8695448081 51.1304551919
BXD77 m 78.4 8.5439399045 95.2695448081 61.5304551919
BXD79 m 122.0 8.5439399045 138.8695448081 105.1304551919
BXD81 m 160.6666666667 11.030178987 182.4451553666 138.8881779667
BXD83 m 82.5 9.552415211 101.3607244702 63.6392755298
BXD84 m 58.6666666667 11.030178987 80.4451553666 36.8881779667
BXD85 m 96.0 9.552415211 114.8607244702 77.1392755298
BXD87 m 62.8 8.5439399045 79.6695448081 45.9304551919
BXD89 m 81.5 9.552415211 100.3607244702 62.6392755298
BXD90 m 96.75 9.552415211 115.6107244702 77.8892755298
BXD95 m 103.0 9.552415211 121.8607244702 84.1392755298
BXD98 m 161.4 8.5439399045 178.2695448081 144.5304551919
BXD99 m 93.2 8.5439399045 110.0695448081 76.3304551919
C57BL/6J m 61.6 8.5439399045 78.4695448081 44.7304551919
DBA/2J m 62.4 8.5439399045 79.2695448081 45.5304551919




  GWAS USING LINEAR MIXED MODELS