Project measure / variable:   Auwerx1   ala_trans_HFD

ID, description, units MPD:111341   ala_trans_HFD   blood alanine transaminase amount   [U/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   52 strains     sex: m     age: 29wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx1 - blood alanine transaminase amount HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested52 strains
Mean of the strain means119.6   U/L
Median of the strain means83.25   U/L
SD of the strain means± 112.1
Coefficient of variation (CV)0.9366
Min–max range of strain means18.2   –   532.5   U/L
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 50 2666051.262 53321.0252 12.3548 < 0.0001
Residuals 164 707791.7333 4315.8033


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 24.2 0.83666   5 0.37417 0.0346 23.0, 25.0 -0.85
BXD100 m 52.4 17.097   5 7.6459 0.3263 32.0, 75.0 -0.6
BXD101 m 279.5 148.9   4 74.43 0.5326 78.0, 427.0 1.43
BXD16 m 102.6 33.396   5 14.935 0.3255 62.0, 145.0 -0.15
BXD27 m 91.75 47.275   4 23.637 0.5153 51.0, 160.0 -0.25
BXD32 m 44.333 20.793   3 12.005 0.469 29.0, 68.0 -0.67
BXD34 m 18.2 7.5631   5 3.3823 0.4156 11.0, 31.0 -0.91
BXD39 m 529.5 194.4   4 97.2 0.3671 364.0, 752.0 3.66
BXD40 m 63.0 24.262   4 12.131 0.3851 48.0, 99.0 -0.51
BXD43 m 74.33 13.503   3 7.796 0.1817 61.0, 88.0 -0.4
BXD44 m 74.2 29.719   5 13.291 0.4005 37.0, 107.0 -0.41
BXD45 m 31.75 3.594   4 1.797 0.1132 27.0, 35.0 -0.78
BXD48 m 86.2 36.867   5 16.488 0.4277 44.0, 132.0 -0.3
BXD48a m 187.3 59.25   3 34.207 0.3163 121.0, 235.0 0.6
BXD49 m 85.5 41.605   4 20.803 0.4866 53.0, 146.0 -0.3
BXD50 m 123.6 102.0   5 45.627 0.8255 52.0, 301.0 0.04
BXD51 m 81.0 37.443   4 18.722 0.4623 44.0, 128.0 -0.34
BXD53 m 246.7 89.58   3 51.72 0.3632 191.0, 350.0 1.13
BXD55 m 36.75 5.8523   4 2.9262 0.1592 30.0, 43.0 -0.74
BXD56 m 78.5 20.506   2   14.5 0.2612 64.0, 93.0 -0.37
BXD6 m 64.0 25.7   5 11.493 0.4016 38.0, 98.0 -0.5
BXD60 m 532.5 78.98   4 39.489 0.1483 450.0, 622.0 3.68
BXD61 m 146.6 33.975   5 15.194 0.2318 110.0, 199.0 0.24
BXD62 m 67.5 30.578   4 15.289 0.453 36.0, 107.0 -0.47
BXD63 m 44.0 0.0   1   0.0 0.0 44.0, 44.0 -0.68
BXD64 m 168.2 70.69   4 35.344 0.4201 91.0, 235.0 0.43
BXD65 m 243.2 65.49   4 32.745 0.2692 160.0, 315.0 1.1
BXD65a m 176.2 42.256   4 21.128 0.2398 115.0, 212.0 0.5
BXD66 m 68.0 13.565   4 6.7823 0.1995 58.0, 88.0 -0.46
BXD67 m 306.6 255.5   5 114.3 0.8334 100.0, 752.0 1.67
BXD68 m 90.25 26.575   4 13.288 0.2945 53.0, 115.0 -0.26
BXD69 m 103.4 48.123   5 21.521 0.4654 64.0, 184.0 -0.14
BXD70 m 54.33 9.2376   3 5.3333 0.17 49.0, 65.0 -0.58
BXD71 m 132.7 73.92   3 42.678 0.5572 75.0, 216.0 0.12
BXD73 m 37.25 16.641   4 8.3204 0.4467 27.0, 62.0 -0.74
BXD73a m 39.0 4.2426   5 1.8974 0.1088 35.0, 45.0 -0.72
BXD73b m 97.8 29.592   5 13.234 0.3026 61.0, 138.0 -0.19
BXD75 m 72.0 31.623   5 14.142 0.4392 37.0, 107.0 -0.43
BXD77 m 162.6 72.41   5 32.385 0.4454 77.0, 262.0 0.38
BXD79 m 132.8 43.205   5 19.322 0.3253 77.0, 189.0 0.12
BXD81 m 88.67 14.503   3 8.3732 0.1636 74.0, 103.0 -0.28
BXD83 m 61.25 14.773   4 7.3866 0.2412 40.0, 74.0 -0.52
BXD84 m 87.67 23.352   3 13.482 0.2664 67.0, 113.0 -0.29
BXD85 m 139.0 44.008   4 22.004 0.3166 75.0, 172.0 0.17
BXD87 m 41.0 18.668   5 8.3487 0.4553 22.0, 63.0 -0.7
BXD89 m 63.0 22.226   4 11.113 0.3528 43.0, 94.0 -0.51
BXD90 m 39.5 7.5498   4 3.7749 0.1911 31.0, 49.0 -0.72
BXD95 m 135.8 68.33   4 34.165 0.5033 69.0, 227.0 0.14
BXD98 m 373.4 69.29   5 30.986 0.1856 274.0, 432.0 2.26
BXD99 m 77.6 18.008   5 8.0536 0.2321 55.0, 103.0 -0.38
C57BL/6J m 32.0 5.6125   5 2.51 0.1754 26.0, 41.0 -0.78
DBA/2J m 32.2 4.3818   5 1.9596 0.1361 28.0, 38.0 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 24.2 29.3795958176 82.2110277666 -33.8110277666
BXD100 m 52.4 29.3795958176 110.4110277666 -5.6110277666
BXD101 m 279.5 32.8473866998 344.3583007654 214.6416992346
BXD16 m 102.6 29.3795958176 160.6110277666 44.5889722334
BXD27 m 91.75 32.8473866998 156.6083007654 26.8916992346
BXD32 m 44.3333333333 37.9288951066 119.2252481455 -30.5585814788
BXD34 m 18.2 29.3795958176 76.2110277666 -39.8110277666
BXD39 m 529.5 32.8473866998 594.3583007654 464.6416992346
BXD40 m 63.0 32.8473866998 127.8583007654 -1.8583007654
BXD43 m 74.3333333333 37.9288951066 149.2252481455 -0.5585814788
BXD44 m 74.2 29.3795958176 132.2110277666 16.1889722334
BXD45 m 31.75 32.8473866998 96.6083007654 -33.1083007654
BXD48 m 86.2 29.3795958176 144.2110277666 28.1889722334
BXD48a m 187.3333333333 37.9288951066 262.2252481455 112.4414185212
BXD49 m 85.5 32.8473866998 150.3583007654 20.6416992346
BXD50 m 123.6 29.3795958176 181.6110277666 65.5889722334
BXD51 m 81.0 32.8473866998 145.8583007654 16.1416992346
BXD53 m 246.6666666667 37.9288951066 321.5585814788 171.7747518545
BXD55 m 36.75 32.8473866998 101.6083007654 -28.1083007654
BXD56 m 78.5 46.4532197594 170.2234885749 -13.2234885749
BXD6 m 64.0 29.3795958176 122.0110277666 5.9889722334
BXD60 m 532.5 32.8473866998 597.3583007654 467.6416992346
BXD61 m 146.6 29.3795958176 204.6110277666 88.5889722334
BXD62 m 67.5 32.8473866998 132.3583007654 2.6416992346
BXD64 m 168.25 32.8473866998 233.1083007654 103.3916992346
BXD65 m 243.25 32.8473866998 308.1083007654 178.3916992346
BXD65a m 176.25 32.8473866998 241.1083007654 111.3916992346
BXD66 m 68.0 32.8473866998 132.8583007654 3.1416992346
BXD67 m 306.6 29.3795958176 364.6110277666 248.5889722334
BXD68 m 90.25 32.8473866998 155.1083007654 25.3916992346
BXD69 m 103.4 29.3795958176 161.4110277666 45.3889722334
BXD70 m 54.3333333333 37.9288951066 129.2252481455 -20.5585814788
BXD71 m 132.6666666667 37.9288951066 207.5585814788 57.7747518545
BXD73 m 37.25 32.8473866998 102.1083007654 -27.6083007654
BXD73a m 39.0 29.3795958176 97.0110277666 -19.0110277666
BXD73b m 97.8 29.3795958176 155.8110277666 39.7889722334
BXD75 m 72.0 29.3795958176 130.0110277666 13.9889722334
BXD77 m 162.6 29.3795958176 220.6110277666 104.5889722334
BXD79 m 132.8 29.3795958176 190.8110277666 74.7889722334
BXD81 m 88.6666666667 37.9288951066 163.5585814788 13.7747518545
BXD83 m 61.25 32.8473866998 126.1083007654 -3.6083007654
BXD84 m 87.6666666667 37.9288951066 162.5585814788 12.7747518545
BXD85 m 139.0 32.8473866998 203.8583007654 74.1416992346
BXD87 m 41.0 29.3795958176 99.0110277666 -17.0110277666
BXD89 m 63.0 32.8473866998 127.8583007654 -1.8583007654
BXD90 m 39.5 32.8473866998 104.3583007654 -25.3583007654
BXD95 m 135.75 32.8473866998 200.6083007654 70.8916992346
BXD98 m 373.4 29.3795958176 431.4110277666 315.3889722334
BXD99 m 77.6 29.3795958176 135.6110277666 19.5889722334
C57BL/6J m 32.0 29.3795958176 90.0110277666 -26.0110277666
DBA/2J m 32.2 29.3795958176 90.2110277666 -25.8110277666




  GWAS USING LINEAR MIXED MODELS