Project measure / variable:   Auwerx1   vo2_max_treadmill2_HFD

ID, description, units MPD:111333   vo2_max_treadmill2_HFD   maximum oxygen consumption, second treadmill training   [mL/kg/min]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 25wks
Procedure monitoring system
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  STRAIN COMPARISON PLOT
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Auwerx1 - maximum oxygen consumption, second treadmill training HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means92.08   mL/kg/min
Median of the strain means91.34   mL/kg/min
SD of the strain means± 17.681
Coefficient of variation (CV)0.192
Min–max range of strain means62.4   –   135.8   mL/kg/min
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 76288.1497 1387.0573 9.6736 < 0.0001
Residuals 188 26956.6167 143.3863


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 107.4 13.278   5 5.938 0.1236 93.0, 121.0 0.87
BXD100 m 93.2 15.106   5 6.7557 0.1621 73.0, 113.0 0.06
BXD101 m 82.75 11.177   4 5.5883 0.1351 73.0, 96.0 -0.53
BXD11 m 109.4 11.76   5 5.2593 0.1075 99.0, 129.0 0.98
BXD12 m 105.6 6.9857   5 3.1241 0.0662 99.0, 117.0 0.76
BXD16 m 70.4 4.7223   5 2.1119 0.0671 66.0, 78.0 -1.23
BXD2 m 84.8 6.6858   5 2.99 0.0788 80.0, 96.0 -0.41
BXD27 m 105.0 13.614   4 6.8069 0.1297 92.0, 124.0 0.73
BXD32 m 96.67 33.501   3 19.342 0.3466 73.0, 135.0 0.26
BXD34 m 94.8 9.985   5 4.4654 0.1053 83.0, 104.0 0.15
BXD39 m 83.4 4.669   5 2.0881 0.056 78.0, 90.0 -0.49
BXD40 m 127.0 15.875   3 9.1652 0.125 115.0, 145.0 1.98
BXD43 m 110.0 3.6056   3 2.0817 0.0328 106.0, 113.0 1.01
BXD44 m 67.5 6.392   8 2.2599 0.0947 60.0, 78.0 -1.39
BXD45 m 116.2 6.8496   4 3.4248 0.0589 110.0, 126.0 1.36
BXD48 m 85.6 15.884   5 7.1035 0.1856 64.0, 103.0 -0.37
BXD48a m 74.67 6.4291   3 3.7118 0.0861 70.0, 82.0 -0.98
BXD49 m 73.75 8.7702   4 4.3851 0.1189 65.0, 85.0 -1.04
BXD50 m 79.8 4.5497   5 2.0347 0.057 75.0, 86.0 -0.69
BXD51 m 75.0 6.6833   4 3.3417 0.0891 69.0, 84.0 -0.97
BXD53 m 90.0 8.2765   5 3.7014 0.092 80.0, 101.0 -0.12
BXD55 m 124.2 9.1424   4 4.5712 0.0736 117.0, 136.0 1.82
BXD56 m 100.5 7.7782   2   5.5 0.0774 95.0, 106.0 0.48
BXD6 m 86.2 7.5631   5 3.3823 0.0877 78.0, 93.0 -0.33
BXD60 m 66.4 3.5071   5 1.5684 0.0528 62.0, 71.0 -1.45
BXD61 m 81.4 2.881   5 1.2884 0.0354 77.0, 85.0 -0.6
BXD62 m 76.5 5.4467   4 2.7234 0.0712 72.0, 83.0 -0.88
BXD63 m 88.0 7.0711   2   5.0 0.0804 83.0, 93.0 -0.23
BXD64 m 82.75 12.23   4 6.1152 0.1478 75.0, 101.0 -0.53
BXD65 m 68.25 0.95743   4 0.47871 0.014 67.0, 69.0 -1.35
BXD65a m 69.75 6.0208   4 3.0104 0.0863 64.0, 78.0 -1.26
BXD66 m 62.4 3.3615   5 1.5033 0.0539 58.0, 67.0 -1.68
BXD67 m 72.6 8.9889   5 4.02 0.1238 64.0, 84.0 -1.1
BXD68 m 106.5 17.02   4 8.5098 0.1598 85.0, 126.0 0.82
BXD69 m 95.0 11.853   5 5.3009 0.1248 78.0, 109.0 0.17
BXD70 m 120.2 25.316   4 12.658 0.2105 95.0, 148.0 1.59
BXD71 m 77.33 5.0332   3 2.9059 0.0651 72.0, 82.0 -0.83
BXD73 m 109.0 12.49   4 6.245 0.1146 96.0, 124.0 0.96
BXD73a m 96.25 7.1356   4 3.5678 0.0741 89.0, 106.0 0.24
BXD73b m 88.4 7.6354   5 3.4147 0.0864 82.0, 99.0 -0.21
BXD75 m 106.6 12.422   5 5.5552 0.1165 93.0, 119.0 0.82
BXD77 m 102.6 22.165   5 9.9126 0.216 81.0, 134.0 0.6
BXD79 m 71.0 2.0   5 0.89443 0.0282 69.0, 73.0 -1.19
BXD8 m 116.4 12.857   5 5.7498 0.1105 102.0, 131.0 1.38
BXD81 m 70.5 5.2599   4 2.63 0.0746 66.0, 78.0 -1.22
BXD83 m 98.75 12.23   4 6.1152 0.1239 91.0, 117.0 0.38
BXD84 m 92.67 27.025   3 15.603 0.2916 62.0, 113.0 0.03
BXD85 m 77.0 5.2915   4 2.6458 0.0687 72.0, 84.0 -0.85
BXD87 m 120.0 11.747   4 5.8737 0.0979 105.0, 132.0 1.58
BXD89 m 105.0 15.769   4 7.8846 0.1502 82.0, 117.0 0.73
BXD90 m 98.5 23.685   4 11.843 0.2405 78.0, 120.0 0.36
BXD95 m 84.4 18.849   5 8.4297 0.2233 60.0, 103.0 -0.43
BXD98 m 71.6 3.7815   5 1.6912 0.0528 67.0, 75.0 -1.16
BXD99 m 101.6 15.043   5 6.7276 0.1481 79.0, 118.0 0.54
C57BL/6J m 99.25 8.0156   4 4.0078 0.0808 93.0, 111.0 0.41
DBA/2J m 135.8 17.225   5 7.7032 0.1268 109.0, 154.0 2.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 107.4 5.3551145434 117.9638346732 96.8361653268
BXD100 m 93.2 5.3551145434 103.7638346732 82.6361653268
BXD101 m 82.75 5.9872000732 94.5607262162 70.9392737838
BXD11 m 109.4 5.3551145434 119.9638346732 98.8361653268
BXD12 m 105.6 5.3551145434 116.1638346732 95.0361653268
BXD16 m 70.4 5.3551145434 80.9638346732 59.8361653268
BXD2 m 84.8 5.3551145434 95.3638346732 74.2361653268
BXD27 m 105.0 5.9872000732 116.8107262162 93.1892737838
BXD32 m 96.6666666667 6.9134231479 110.3045185872 83.0288147462
BXD34 m 94.8 5.3551145434 105.3638346732 84.2361653268
BXD39 m 83.4 5.3551145434 93.9638346732 72.8361653268
BXD40 m 127.0 6.9134231479 140.6378519205 113.3621480795
BXD43 m 110.0 6.9134231479 123.6378519205 96.3621480795
BXD44 m 67.5 4.2335897721 75.8514445982 59.1485554018
BXD45 m 116.25 5.9872000732 128.0607262162 104.4392737838
BXD48 m 85.6 5.3551145434 96.1638346732 75.0361653268
BXD48a m 74.6666666667 6.9134231479 88.3045185872 61.0288147462
BXD49 m 73.75 5.9872000732 85.5607262162 61.9392737838
BXD50 m 79.8 5.3551145434 90.3638346732 69.2361653268
BXD51 m 75.0 5.9872000732 86.8107262162 63.1892737838
BXD53 m 90.0 5.3551145434 100.5638346732 79.4361653268
BXD55 m 124.25 5.9872000732 136.0607262162 112.4392737838
BXD56 m 100.5 8.4671795441 117.2028891964 83.7971108036
BXD6 m 86.2 5.3551145434 96.7638346732 75.6361653268
BXD60 m 66.4 5.3551145434 76.9638346732 55.8361653268
BXD61 m 81.4 5.3551145434 91.9638346732 70.8361653268
BXD62 m 76.5 5.9872000732 88.3107262162 64.6892737838
BXD63 m 88.0 8.4671795441 104.7028891964 71.2971108036
BXD64 m 82.75 5.9872000732 94.5607262162 70.9392737838
BXD65 m 68.25 5.9872000732 80.0607262162 56.4392737838
BXD65a m 69.75 5.9872000732 81.5607262162 57.9392737838
BXD66 m 62.4 5.3551145434 72.9638346732 51.8361653268
BXD67 m 72.6 5.3551145434 83.1638346732 62.0361653268
BXD68 m 106.5 5.9872000732 118.3107262162 94.6892737838
BXD69 m 95.0 5.3551145434 105.5638346732 84.4361653268
BXD70 m 120.25 5.9872000732 132.0607262162 108.4392737838
BXD71 m 77.3333333333 6.9134231479 90.9711852538 63.6954814129
BXD73 m 109.0 5.9872000732 120.8107262162 97.1892737838
BXD73a m 96.25 5.9872000732 108.0607262162 84.4392737838
BXD73b m 88.4 5.3551145434 98.9638346732 77.8361653268
BXD75 m 106.6 5.3551145434 117.1638346732 96.0361653268
BXD77 m 102.6 5.3551145434 113.1638346732 92.0361653268
BXD79 m 71.0 5.3551145434 81.5638346732 60.4361653268
BXD8 m 116.4 5.3551145434 126.9638346732 105.8361653268
BXD81 m 70.5 5.9872000732 82.3107262162 58.6892737838
BXD83 m 98.75 5.9872000732 110.5607262162 86.9392737838
BXD84 m 92.6666666667 6.9134231479 106.3045185871 79.0288147462
BXD85 m 77.0 5.9872000732 88.8107262162 65.1892737838
BXD87 m 120.0 5.9872000732 131.8107262162 108.1892737838
BXD89 m 105.0 5.9872000732 116.8107262162 93.1892737838
BXD90 m 98.5 5.9872000732 110.3107262162 86.6892737838
BXD95 m 84.4 5.3551145434 94.9638346732 73.8361653268
BXD98 m 71.6 5.3551145434 82.1638346732 61.0361653268
BXD99 m 101.6 5.3551145434 112.1638346732 91.0361653268
C57BL/6J m 99.25 5.9872000732 111.0607262162 87.4392737838
DBA/2J m 135.8 5.3551145434 146.3638346732 125.2361653268




  GWAS USING LINEAR MIXED MODELS