Project measure / variable:   Auwerx1   vo2_max_treadmill1_HFD

ID, description, units MPD:111315   vo2_max_treadmill1_HFD   maximum oxygen consumption, first treadmill training   [mL/kg/min]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   55 strains     sex: m     age: 23wks
Procedure monitoring system
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  STRAIN COMPARISON PLOT
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Auwerx1 - maximum oxygen consumption, first treadmill training HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested55 strains
Mean of the strain means81.44   mL/kg/min
Median of the strain means78.4   mL/kg/min
SD of the strain means± 12.754
Coefficient of variation (CV)0.1566
Min–max range of strain means64.2   –   112.2   mL/kg/min
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 54 39309.0695 727.9457 14.6912 < 0.0001
Residuals 186 9216.25 49.5497


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 80.4 9.3434   5 4.1785 0.1162 72.0, 95.0 -0.08
BXD100 m 85.0 4.5277   5 2.0248 0.0533 80.0, 90.0 0.28
BXD101 m 67.0 2.9439   4 1.472 0.0439 64.0, 71.0 -1.13
BXD11 m 91.0 8.8034   5 3.937 0.0967 79.0, 102.0 0.75
BXD12 m 109.4 11.76   5 5.2593 0.1075 99.0, 129.0 2.19
BXD16 m 71.8 0.83666   5 0.37417 0.0117 71.0, 73.0 -0.76
BXD2 m 75.8 9.1488   5 4.0915 0.1207 66.0, 89.0 -0.44
BXD27 m 76.33 4.1633   3 2.4037 0.0545 73.0, 81.0 -0.4
BXD32 m 73.0 3.4641   3 2.0 0.0475 69.0, 75.0 -0.66
BXD34 m 85.2 9.1761   5 4.1037 0.1077 77.0, 99.0 0.29
BXD39 m 74.4 2.881   5 1.2884 0.0387 70.0, 77.0 -0.55
BXD40 m 112.2 4.5   4 2.25 0.0401 106.0, 116.0 2.41
BXD43 m 88.67 5.5076   3 3.1798 0.0621 83.0, 94.0 0.57
BXD44 m 66.33 6.1237   9 2.0412 0.0923 57.0, 74.0 -1.18
BXD45 m 98.0 3.4641   4 1.7321 0.0353 95.0, 103.0 1.3
BXD48 m 64.2 0.83666   5 0.37417 0.013 63.0, 65.0 -1.35
BXD48a m 74.67 6.4291   3 3.7118 0.0861 70.0, 82.0 -0.53
BXD49 m 68.5 9.037   4 4.5185 0.1319 58.0, 79.0 -1.01
BXD50 m 75.0 6.0828   5 2.7203 0.0811 67.0, 82.0 -0.5
BXD51 m 69.25 4.7871   4 2.3936 0.0691 64.0, 75.0 -0.96
BXD53 m 77.8 4.6043   5 2.0591 0.0592 72.0, 82.0 -0.29
BXD55 m 96.0 10.296   4 5.1478 0.1072 83.0, 108.0 1.14
BXD56 m 81.67 1.5275   3 0.88192 0.0187 80.0, 83.0 0.02
BXD6 m 78.4 8.2644   5 3.6959 0.1054 69.0, 88.0 -0.24
BXD61 m 80.4 4.7749   5 2.1354 0.0594 74.0, 86.0 -0.08
BXD62 m 74.25 2.3629   4 1.1815 0.0318 71.0, 76.0 -0.56
BXD63 m 85.0 2.8284   2   2.0 0.0333 83.0, 87.0 0.28
BXD64 m 77.25 7.1822   4 3.5911 0.093 73.0, 88.0 -0.33
BXD65 m 65.5 1.291   4 0.6455 0.0197 64.0, 67.0 -1.25
BXD65a m 65.75 5.058   4 2.529 0.0769 60.0, 70.0 -1.23
BXD66 m 65.8 8.2885   5 3.7068 0.126 55.0, 78.0 -1.23
BXD67 m 66.2 5.8907   5 2.6344 0.089 60.0, 73.0 -1.19
BXD68 m 83.25 5.7373   4 2.8687 0.0689 75.0, 88.0 0.14
BXD69 m 91.6 2.7928   5 1.249 0.0305 89.0, 95.0 0.8
BXD70 m 93.75 10.34   4 5.17 0.1103 81.0, 106.0 0.97
BXD71 m 74.67 3.7859   3 2.1858 0.0507 72.0, 79.0 -0.53
BXD73 m 108.2 5.909   4 2.9545 0.0546 100.0, 114.0 2.1
BXD73a m 80.75 6.1305   4 3.0653 0.0759 73.0, 87.0 -0.05
BXD73b m 79.6 4.5056   5 2.0149 0.0566 72.0, 83.0 -0.14
BXD75 m 95.0 9.5917   5 4.2895 0.101 86.0, 110.0 1.06
BXD77 m 85.0 6.7823   5 3.0332 0.0798 75.0, 93.0 0.28
BXD79 m 72.6 1.1402   5 0.5099 0.0157 71.0, 74.0 -0.69
BXD8 m 101.0 7.0   5 3.1305 0.0693 93.0, 112.0 1.53
BXD81 m 65.25 1.5   4 0.75 0.023 63.0, 66.0 -1.27
BXD83 m 89.25 6.1305   4 3.0653 0.0687 83.0, 97.0 0.61
BXD84 m 72.33 3.0551   3 1.7638 0.0422 69.0, 75.0 -0.71
BXD85 m 70.75 2.2174   4 1.1087 0.0313 68.0, 73.0 -0.84
BXD87 m 106.2 10.243   4 5.1214 0.0964 91.0, 113.0 1.94
BXD89 m 99.5 8.7369   4 4.3684 0.0878 91.0, 108.0 1.42
BXD90 m 87.75 23.042   4 11.521 0.2626 66.0, 111.0 0.49
BXD95 m 71.6 8.6197   5 3.8549 0.1204 64.0, 86.0 -0.77
BXD98 m 67.6 2.881   5 1.2884 0.0426 64.0, 72.0 -1.08
BXD99 m 75.4 4.0988   5 1.833 0.0544 71.0, 82.0 -0.47
C57BL/6J m 87.25 6.3966   4 3.1983 0.0733 79.0, 94.0 0.46
DBA/2J m 100.6 9.1815   5 4.1061 0.0913 92.0, 116.0 1.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 80.4 3.1480067085 86.6103879933 74.1896120067
BXD100 m 85.0 3.1480067085 91.2103879933 78.7896120067
BXD101 m 67.0 3.5195784969 73.9434248599 60.0565751401
BXD11 m 91.0 3.1480067085 97.2103879933 84.7896120067
BXD12 m 109.4 3.1480067085 115.6103879933 103.1896120067
BXD16 m 71.8 3.1480067085 78.0103879933 65.5896120067
BXD2 m 75.8 3.1480067085 82.0103879933 69.5896120067
BXD27 m 76.3333333333 4.0640591852 84.3509097572 68.3157569095
BXD32 m 73.0 4.0640591852 81.0175764239 64.9824235761
BXD34 m 85.2 3.1480067085 91.4103879933 78.9896120067
BXD39 m 74.4 3.1480067085 80.6103879933 68.1896120067
BXD40 m 112.25 3.5195784969 119.1934248599 105.3065751401
BXD43 m 88.6666666667 4.0640591852 96.6842430905 80.6490902428
BXD44 m 66.3333333333 2.3463856646 70.9622832399 61.7043834268
BXD45 m 98.0 3.5195784969 104.9434248599 91.0565751401
BXD48 m 64.2 3.1480067085 70.4103879933 57.9896120067
BXD48a m 74.6666666667 4.0640591852 82.6842430905 66.6490902428
BXD49 m 68.5 3.5195784969 75.4434248599 61.5565751401
BXD50 m 75.0 3.1480067085 81.2103879933 68.7896120067
BXD51 m 69.25 3.5195784969 76.1934248599 62.3065751401
BXD53 m 77.8 3.1480067085 84.0103879933 71.5896120067
BXD55 m 96.0 3.5195784969 102.9434248599 89.0565751401
BXD56 m 81.6666666667 4.0640591852 89.6842430905 73.6490902428
BXD6 m 78.4 3.1480067085 84.6103879933 72.1896120067
BXD61 m 80.4 3.1480067085 86.6103879933 74.1896120067
BXD62 m 74.25 3.5195784969 81.1934248599 67.3065751401
BXD63 m 85.0 4.9774356441 94.8194856061 75.1805143939
BXD64 m 77.25 3.5195784969 84.1934248599 70.3065751401
BXD65 m 65.5 3.5195784969 72.4434248599 58.5565751401
BXD65a m 65.75 3.5195784969 72.6934248599 58.8065751401
BXD66 m 65.8 3.1480067085 72.0103879933 59.5896120067
BXD67 m 66.2 3.1480067085 72.4103879933 59.9896120067
BXD68 m 83.25 3.5195784969 90.1934248599 76.3065751401
BXD69 m 91.6 3.1480067085 97.8103879933 85.3896120067
BXD70 m 93.75 3.5195784969 100.6934248599 86.8065751401
BXD71 m 74.6666666667 4.0640591852 82.6842430905 66.6490902428
BXD73 m 108.25 3.5195784969 115.1934248599 101.3065751401
BXD73a m 80.75 3.5195784969 87.6934248599 73.8065751401
BXD73b m 79.6 3.1480067085 85.8103879933 73.3896120067
BXD75 m 95.0 3.1480067085 101.2103879933 88.7896120067
BXD77 m 85.0 3.1480067085 91.2103879933 78.7896120067
BXD79 m 72.6 3.1480067085 78.8103879933 66.3896120067
BXD8 m 101.0 3.1480067085 107.2103879933 94.7896120067
BXD81 m 65.25 3.5195784969 72.1934248599 58.3065751401
BXD83 m 89.25 3.5195784969 96.1934248599 82.3065751401
BXD84 m 72.3333333333 4.0640591852 80.3509097572 64.3157569095
BXD85 m 70.75 3.5195784969 77.6934248599 63.8065751401
BXD87 m 106.25 3.5195784969 113.1934248599 99.3065751401
BXD89 m 99.5 3.5195784969 106.4434248599 92.5565751401
BXD90 m 87.75 3.5195784969 94.6934248599 80.8065751401
BXD95 m 71.6 3.1480067085 77.8103879933 65.3896120067
BXD98 m 67.6 3.1480067085 73.8103879933 61.3896120067
BXD99 m 75.4 3.1480067085 81.6103879933 69.1896120067
C57BL/6J m 87.25 3.5195784969 94.1934248599 80.3065751401
DBA/2J m 100.6 3.1480067085 106.8103879933 94.3896120067




  GWAS USING LINEAR MIXED MODELS