Project measure / variable:   Auwerx1   diastoloc_bp_HFD

ID, description, units MPD:111277   diastoloc_bp_HFD   diastolic blood pressure   [mmHg]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 19wks
Procedure tail cuff
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  STRAIN COMPARISON PLOT
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Auwerx1 - diastolic blood pressure HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means79.06   mmHg
Median of the strain means77.38   mmHg
SD of the strain means± 11.745
Coefficient of variation (CV)0.1486
Min–max range of strain means53.75   –   116.8   mmHg
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 30924.4238 562.2623 3.2236 < 0.0001
Residuals 179 31221.5167 174.4219


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 78.2 15.515   5 6.9383 0.1984 59.0, 99.0 -0.07
BXD100 m 53.75 7.4106   4 3.7053 0.1379 47.0, 64.0 -2.16
BXD101 m 80.25 8.5781   4 4.289 0.1069 70.0, 91.0 0.1
BXD11 m 66.4 9.7108   5 4.3428 0.1462 50.0, 75.0 -1.08
BXD12 m 70.2 9.3113   5 4.1641 0.1326 62.0, 86.0 -0.75
BXD16 m 88.0 10.954   5 4.899 0.1245 75.0, 99.0 0.76
BXD2 m 76.2 8.5849   5 3.8393 0.1127 65.0, 87.0 -0.24
BXD27 m 90.5 1.291   4 0.6455 0.0143 89.0, 92.0 0.97
BXD32 m 62.0 7.0   3 4.0415 0.1129 54.0, 67.0 -1.45
BXD34 m 80.0 16.447   5 7.3553 0.2056 56.0, 96.0 0.08
BXD39 m 60.4 6.7676   5 3.0265 0.112 51.0, 69.0 -1.59
BXD40 m 76.0 9.5568   4 4.7784 0.1257 63.0, 86.0 -0.26
BXD43 m 68.67 4.6188   3 2.6667 0.0673 66.0, 74.0 -0.88
BXD44 m 83.5 15.194   8 5.3719 0.182 56.0, 100.0 0.38
BXD45 m 79.75 15.13   4 7.565 0.1897 59.0, 91.0 0.06
BXD48 m 72.5 28.337   4 14.169 0.3909 41.0, 102.0 -0.56
BXD48a m 70.67 6.8069   3 3.9299 0.0963 63.0, 76.0 -0.71
BXD49 m 65.75 11.73   4 5.8648 0.1784 54.0, 82.0 -1.13
BXD50 m 76.5 10.878   4 5.4391 0.1422 65.0, 91.0 -0.22
BXD51 m 63.25 13.475   4 6.7376 0.213 44.0, 75.0 -1.35
BXD53 m 75.2 14.342   5 6.414 0.1907 64.0, 99.0 -0.33
BXD55 m 87.75 18.998   4 9.4989 0.2165 68.0, 105.0 0.74
BXD56 m 85.33 25.813   3 14.903 0.3025 68.0, 115.0 0.53
BXD6 m 69.4 9.7108   5 4.3428 0.1399 56.0, 81.0 -0.82
BXD60 m 93.2 9.094   5 4.0669 0.0976 85.0, 104.0 1.2
BXD61 m 83.0 12.028   4 6.0139 0.1449 71.0, 98.0 0.34
BXD62 m 72.25 13.351   4 6.6755 0.1848 61.0, 90.0 -0.58
BXD63 m 78.0 14.989   4 7.4944 0.1922 68.0, 100.0 -0.09
BXD64 m 94.5 12.45   4 6.2249 0.1317 86.0, 113.0 1.31
BXD65 m 81.5 8.0623   4 4.0311 0.0989 73.0, 91.0 0.21
BXD65a m 79.75 16.46   4 8.2298 0.2064 65.0, 94.0 0.06
BXD66 m 76.25 20.998   4 10.499 0.2754 53.0, 104.0 -0.24
BXD67 m 70.4 6.8044   5 3.043 0.0967 61.0, 78.0 -0.74
BXD68 m 85.5 11.475   4 5.7373 0.1342 72.0, 96.0 0.55
BXD69 m 76.75 12.176   4 6.0879 0.1586 61.0, 89.0 -0.2
BXD70 m 112.8 24.24   4 12.12 0.215 89.0, 140.0 2.87
BXD71 m 78.25 13.889   4 6.9447 0.1775 61.0, 90.0 -0.07
BXD73 m 83.75 11.615   4 5.8077 0.1387 68.0, 96.0 0.4
BXD73a m 95.0 8.756   4 4.378 0.0922 87.0, 106.0 1.36
BXD73b m 116.8 29.848   4 14.924 0.2557 87.0, 157.0 3.21
BXD75 m 71.75 8.2614   4 4.1307 0.1151 61.0, 80.0 -0.62
BXD77 m 75.2 7.7589   5 3.4699 0.1032 64.0, 85.0 -0.33
BXD79 m 63.0 15.166   4 7.5829 0.2407 47.0, 80.0 -1.37
BXD8 m 70.0 6.6332   4 3.3166 0.0948 61.0, 75.0 -0.77
BXD81 m 94.25 17.5   4 8.75 0.1857 73.0, 113.0 1.29
BXD83 m 79.75 6.5   4 3.25 0.0815 71.0, 86.0 0.06
BXD84 m 72.67 12.741   3 7.356 0.1753 58.0, 81.0 -0.54
BXD85 m 72.5 8.1035   4 4.0517 0.1118 65.0, 80.0 -0.56
BXD87 m 87.75 12.868   4 6.434 0.1466 74.0, 104.0 0.74
BXD89 m 96.25 14.033   4 7.0163 0.1458 79.0, 110.0 1.46
BXD90 m 82.75 12.842   4 6.421 0.1552 64.0, 92.0 0.31
BXD95 m 87.25 9.6047   4 4.8023 0.1101 73.0, 94.0 0.7
BXD98 m 72.0 9.8995   4 4.9497 0.1375 65.0, 86.0 -0.6
BXD99 m 93.5 8.6987   4 4.3493 0.093 86.0, 106.0 1.23
C57BL/6J m 74.25 7.8899   4 3.9449 0.1063 65.0, 83.0 -0.41
DBA/2J m 76.75 6.1305   4 3.0653 0.0799 68.0, 81.0 -0.2


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 78.2 5.9062997015 89.8549332949 66.5450667051
BXD100 m 53.75 6.603443814 66.7806115603 40.7193884397
BXD101 m 80.25 6.603443814 93.2806115603 67.2193884397
BXD11 m 66.4 5.9062997015 78.0549332949 54.7450667051
BXD12 m 70.2 5.9062997015 81.8549332949 58.5450667051
BXD16 m 88.0 5.9062997015 99.6549332949 76.3450667051
BXD2 m 76.2 5.9062997015 87.8549332949 64.5450667051
BXD27 m 90.5 6.603443814 103.5306115603 77.4693884397
BXD32 m 62.0 7.6250001272 77.046454184 46.953545816
BXD34 m 80.0 5.9062997015 91.6549332949 68.3450667051
BXD39 m 60.4 5.9062997015 72.0549332949 48.7450667051
BXD40 m 76.0 6.603443814 89.0306115603 62.9693884397
BXD43 m 68.6666666667 7.6250001272 83.7131208507 53.6202124826
BXD44 m 83.5 4.6693399001 92.7140337973 74.2859662027
BXD45 m 79.75 6.603443814 92.7806115603 66.7193884397
BXD48 m 72.5 6.603443814 85.5306115603 59.4693884397
BXD48a m 70.6666666667 7.6250001272 85.7131208507 55.6202124826
BXD49 m 65.75 6.603443814 78.7806115603 52.7193884397
BXD50 m 76.5 6.603443814 89.5306115603 63.4693884397
BXD51 m 63.25 6.603443814 76.2806115603 50.2193884397
BXD53 m 75.2 5.9062997015 86.8549332949 63.5450667051
BXD55 m 87.75 6.603443814 100.7806115603 74.7193884397
BXD56 m 85.3333333333 7.6250001272 100.3797875174 70.2868791493
BXD6 m 69.4 5.9062997015 81.0549332949 57.7450667051
BXD60 m 93.2 5.9062997015 104.8549332949 81.5450667051
BXD61 m 83.0 6.603443814 96.0306115603 69.9693884397
BXD62 m 72.25 6.603443814 85.2806115603 59.2193884397
BXD63 m 78.0 6.603443814 91.0306115603 64.9693884397
BXD64 m 94.5 6.603443814 107.5306115603 81.4693884397
BXD65 m 81.5 6.603443814 94.5306115603 68.4693884397
BXD65a m 79.75 6.603443814 92.7806115603 66.7193884397
BXD66 m 76.25 6.603443814 89.2806115603 63.2193884397
BXD67 m 70.4 5.9062997015 82.0549332949 58.7450667051
BXD68 m 85.5 6.603443814 98.5306115603 72.4693884397
BXD69 m 76.75 6.603443814 89.7806115603 63.7193884397
BXD70 m 112.75 6.603443814 125.7806115603 99.7193884397
BXD71 m 78.25 6.603443814 91.2806115603 65.2193884397
BXD73 m 83.75 6.603443814 96.7806115603 70.7193884397
BXD73a m 95.0 6.603443814 108.0306115603 81.9693884397
BXD73b m 116.75 6.603443814 129.7806115603 103.7193884397
BXD75 m 71.75 6.603443814 84.7806115603 58.7193884397
BXD77 m 75.2 5.9062997015 86.8549332949 63.5450667051
BXD79 m 63.0 6.603443814 76.0306115603 49.9693884397
BXD8 m 70.0 6.603443814 83.0306115603 56.9693884397
BXD81 m 94.25 6.603443814 107.2806115603 81.2193884397
BXD83 m 79.75 6.603443814 92.7806115603 66.7193884397
BXD84 m 72.6666666667 7.6250001272 87.7131208507 57.6202124826
BXD85 m 72.5 6.603443814 85.5306115603 59.4693884397
BXD87 m 87.75 6.603443814 100.7806115603 74.7193884397
BXD89 m 96.25 6.603443814 109.2806115603 83.2193884397
BXD90 m 82.75 6.603443814 95.7806115603 69.7193884397
BXD95 m 87.25 6.603443814 100.2806115603 74.2193884397
BXD98 m 72.0 6.603443814 85.0306115603 58.9693884397
BXD99 m 93.5 6.603443814 106.5306115603 80.4693884397
C57BL/6J m 74.25 6.603443814 87.2806115603 61.2193884397
DBA/2J m 76.75 6.603443814 89.7806115603 63.7193884397




  GWAS USING LINEAR MIXED MODELS