Project measure / variable:   Auwerx1   ogtt_ins_auc_HFD

ID, description, units MPD:111271   ogtt_ins_auc_HFD   insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast)   [AUC]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure hormone quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx1 - insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast) HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means100.5   AUC
Median of the strain means97.78   AUC
SD of the strain means± 61.97
Coefficient of variation (CV)0.6169
Min–max range of strain means18.175   –   331.1   AUC
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 839294.4948 15259.8999 12.2068 < 0.0001
Residuals 178 222520.9519 1250.1177


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 33.72 10.274   5 4.5947 0.3047 21.2, 48.8 -1.08
BXD100 m 129.3 55.96   5 25.026 0.4329 79.76, 212.2 0.47
BXD101 m 99.52 21.299   4 10.649 0.214 84.14, 131.0 -0.02
BXD11 m 84.04 58.08   5 25.973 0.691 23.76, 148.4 -0.26
BXD12 m 25.488 10.754   5 4.8093 0.4219 15.87, 43.98 -1.21
BXD16 m 98.07 49.776   5 22.26 0.5076 47.1, 177.8 -0.04
BXD2 m 107.8 46.182   5 20.653 0.4285 44.58, 152.9 0.12
BXD27 m 113.4 38.03   4 19.015 0.3352 87.9, 169.7 0.21
BXD32 m 157.8 4.2194   3 2.4361 0.0267 155.2, 162.7 0.93
BXD34 m 42.994 35.605   5 15.923 0.8281 13.84, 103.0 -0.93
BXD39 m 181.6 34.964   5 15.636 0.1925 127.4, 219.0 1.31
BXD40 m 18.175 4.9311   4 2.4656 0.2713 11.1, 21.6 -1.33
BXD43 m 26.69 6.042   3 3.4884 0.2264 20.88, 32.94 -1.19
BXD44 m 120.3 50.53   6 20.627 0.4202 52.96, 170.6 0.32
BXD45 m 97.54 32.113   4 16.057 0.3292 66.32, 136.6 -0.05
BXD48 m 105.5 23.335   3 13.472 0.2213 80.36, 126.5 0.08
BXD48a m 331.1 22.815   3 13.172 0.0689 311.2, 356.0 3.72
BXD49 m 54.24 36.611   3 21.137 0.6749 27.65, 96.0 -0.75
BXD50 m 122.0 48.044   5 21.486 0.3937 50.33, 171.6 0.35
BXD51 m 82.79 19.311   4 9.6557 0.2333 65.91, 109.9 -0.29
BXD53 m 52.97 17.455   5 7.806 0.3295 25.95, 71.18 -0.77
BXD55 m 45.962 10.969   4 5.4847 0.2387 37.97, 61.95 -0.88
BXD56 m 58.92 5.1777   4 2.5888 0.0879 51.42, 62.5 -0.67
BXD6 m 65.65 35.003   5 15.654 0.5331 17.72, 113.5 -0.56
BXD60 m 176.6 10.407   5 4.654 0.0589 161.0, 190.0 1.23
BXD61 m 263.5 70.63   5 31.588 0.2681 142.2, 326.5 2.63
BXD62 m 103.1 39.665   3 22.9 0.3849 68.99, 146.6 0.04
BXD63 m 100.2 6.2532   4 3.1266 0.0624 96.17, 109.5 0.0
BXD64 m 28.34 13.491   3 7.789 0.476 13.16, 38.96 -1.16
BXD65 m 156.4 10.536   2   7.45 0.0673 149.0, 163.9 0.9
BXD65a m 120.6 23.708   4 11.854 0.1967 92.83, 145.1 0.33
BXD66 m 215.6 73.63   4 36.813 0.3415 127.4, 284.7 1.86
BXD67 m 48.766 14.377   5 6.4295 0.2948 35.78, 72.45 -0.83
BXD68 m 25.33 11.973   4 5.9863 0.4727 8.858, 34.46 -1.21
BXD69 m 48.51 16.927   3 9.7728 0.3489 31.87, 65.71 -0.84
BXD70 m 104.8 42.39   3 24.474 0.4046 63.62, 148.3 0.07
BXD71 m 72.15 25.594   3 14.776 0.3547 57.02, 101.7 -0.46
BXD73 m 82.66 23.006   4 11.503 0.2783 62.03, 113.4 -0.29
BXD73a m 141.5 72.35   4 36.174 0.5113 56.48, 233.4 0.66
BXD73b m 70.85 18.677   5 8.3527 0.2636 53.95, 102.5 -0.48
BXD75 m 172.1 58.07   5 25.97 0.3375 106.8, 249.2 1.16
BXD77 m 101.3 38.82   5 17.361 0.3834 46.4, 139.2 0.01
BXD79 m 70.73 21.175   5 9.4699 0.2994 43.95, 91.97 -0.48
BXD8 m 19.969 9.7063   5 4.3408 0.4861 8.593, 32.3 -1.3
BXD81 m 118.9 4.9   3 2.829 0.0412 114.0, 123.8 0.3
BXD83 m 205.7 65.11   4 32.554 0.3166 111.5, 250.1 1.7
BXD84 m 61.58 14.167   3 8.1794 0.23 48.13, 76.37 -0.63
BXD85 m 68.87 29.282   4 14.641 0.4252 49.22, 112.4 -0.51
BXD87 m 100.5 6.7541   5 3.0205 0.0672 89.53, 107.2 0.0
BXD89 m 93.66 40.033   4 20.016 0.4274 34.94, 120.5 -0.11
BXD90 m 59.25 16.004   4 8.0019 0.2701 45.23, 79.27 -0.66
BXD95 m 98.02 35.756   5 15.99 0.3648 45.24, 144.2 -0.04
BXD98 m 56.81 12.687   4 6.3437 0.2233 45.47, 74.78 -0.7
BXD99 m 63.87 6.8738   5 3.074 0.1076 55.2, 70.53 -0.59
C57BL/6J m 127.2 20.395   4 10.197 0.1604 107.6, 155.1 0.43
DBA/2J m 192.7 44.862   4 22.431 0.2328 135.2, 231.1 1.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 33.72 15.8121327286 64.9233605339 2.5166394661
BXD100 m 129.266 15.8121327286 160.4693605339 98.0626394661
BXD101 m 99.52 17.6785018252 134.4064176401 64.6335823599
BXD11 m 84.042 15.8121327286 115.2453605339 52.8386394661
BXD12 m 25.488 15.8121327286 56.6913605339 -5.7153605339
BXD16 m 98.07 15.8121327286 129.2733605339 66.8666394661
BXD2 m 107.768 15.8121327286 138.9713605339 76.5646394661
BXD27 m 113.445 17.6785018252 148.3314176401 78.5585823599
BXD32 m 157.8333333333 20.4133755753 198.1166985644 117.5499681022
BXD34 m 42.994 15.8121327286 74.1973605339 11.7906394661
BXD39 m 181.6 15.8121327286 212.8033605339 150.3966394661
BXD40 m 18.175 17.6785018252 53.0614176401 -16.7114176401
BXD43 m 26.69 20.4133755753 66.9733652311 -13.5933652311
BXD44 m 120.2533333333 14.4344362962 148.7379740573 91.7686926094
BXD45 m 97.5425 17.6785018252 132.4289176401 62.6560823599
BXD48 m 105.4533333333 20.4133755753 145.7366985644 65.1699681022
BXD48a m 331.1 20.4133755753 371.3833652311 290.8166347689
BXD49 m 54.2433333333 20.4133755753 94.5266985644 13.9599681022
BXD50 m 122.046 15.8121327286 153.2493605339 90.8426394661
BXD51 m 82.7875 17.6785018252 117.6739176401 47.9010823599
BXD53 m 52.966 15.8121327286 84.1693605339 21.7626394661
BXD55 m 45.9625 17.6785018252 80.8489176401 11.0760823599
BXD56 m 58.915 17.6785018252 93.8014176401 24.0285823599
BXD6 m 65.654 15.8121327286 96.8573605339 34.4506394661
BXD60 m 176.6 15.8121327286 207.8033605339 145.3966394661
BXD61 m 263.46 15.8121327286 294.6633605339 232.2566394661
BXD62 m 103.0533333333 20.4133755753 143.3366985644 62.7699681022
BXD63 m 100.17 17.6785018252 135.0564176401 65.2835823599
BXD64 m 28.34 20.4133755753 68.6233652311 -11.9433652311
BXD65 m 156.45 25.0011770437 205.7868449692 107.1131550308
BXD65a m 120.5575 17.6785018252 155.4439176401 85.6710823599
BXD66 m 215.575 17.6785018252 250.4614176401 180.6885823599
BXD67 m 48.766 15.8121327286 79.9693605339 17.5626394661
BXD68 m 25.3295 17.6785018252 60.2159176401 -9.5569176401
BXD69 m 48.51 20.4133755753 88.7933652311 8.2266347689
BXD70 m 104.7733333333 20.4133755753 145.0566985644 64.4899681022
BXD71 m 72.15 20.4133755753 112.4333652311 31.8666347689
BXD73 m 82.66 17.6785018252 117.5464176401 47.7735823599
BXD73a m 141.495 17.6785018252 176.3814176401 106.6085823599
BXD73b m 70.854 15.8121327286 102.0573605339 39.6506394661
BXD75 m 172.06 15.8121327286 203.2633605339 140.8566394661
BXD77 m 101.26 15.8121327286 132.4633605339 70.0566394661
BXD79 m 70.73 15.8121327286 101.9333605339 39.5266394661
BXD8 m 19.9686 15.8121327286 51.1719605339 -11.2347605339
BXD81 m 118.9 20.4133755753 159.1833652311 78.6166347689
BXD83 m 205.675 17.6785018252 240.5614176401 170.7885823599
BXD84 m 61.5833333333 20.4133755753 101.8666985644 21.2999681022
BXD85 m 68.87 17.6785018252 103.7564176401 33.9835823599
BXD87 m 100.464 15.8121327286 131.6673605339 69.2606394661
BXD89 m 93.66 17.6785018252 128.5464176401 58.7735823599
BXD90 m 59.2475 17.6785018252 94.1339176401 24.3610823599
BXD95 m 98.018 15.8121327286 129.2213605339 66.8146394661
BXD98 m 56.815 17.6785018252 91.7014176401 21.9285823599
BXD99 m 63.872 15.8121327286 95.0753605339 32.6686394661
C57BL/6J m 127.175 17.6785018252 162.0614176401 92.2885823599
DBA/2J m 192.675 17.6785018252 227.5614176401 157.7885823599




  GWAS USING LINEAR MIXED MODELS