Project measure / variable:   Auwerx1   ogtt_ins_auc_HFD

ID, description, units MPD:111271   ogtt_ins_auc_HFD   insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast)   [AUC]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure hormone quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx1 - insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast) HFD

BXD48aBXD61BXD66BXD83DBA/2JBXD39BXD60BXD75BXD32BXD65BXD73aBXD100C57BL/6JBXD50BXD65aBXD44BXD81BXD27BXD2BXD48BXD70BXD62BXD77BXD87BXD63BXD101BXD16BXD95BXD45BXD89BXD11BXD51BXD73BXD71BXD73bBXD79BXD85BXD6BXD99BXD84BXD90BXD56BXD98BXD49BXD53BXD67BXD69BXD55BXD34BXD1BXD64BXD43BXD12BXD68BXD8BXD40 AUC 050100150200250300350femalemale


  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means100.5   AUC
Median of the strain means97.78   AUC
SD of the strain means± 61.97
Coefficient of variation (CV)0.6169
Min–max range of strain means18.175   –   331.1   AUC
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 839294.4948 15259.8999 12.2068 < 0.0001
Residuals 178 222520.9519 1250.1177


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page: 1 - 10 / 56 (56)
Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
BXD1 m 33.72 10.274   5 4.5947 0.3047 21.2, 48.8 -1.08
BXD100 m 129.3 55.96   5 25.026 0.4329 79.76, 212.2 0.47
BXD101 m 99.52 21.299   4 10.649 0.214 84.14, 131.0 -0.02
BXD11 m 84.04 58.08   5 25.973 0.691 23.76, 148.4 -0.26
BXD12 m 25.488 10.754   5 4.8093 0.4219 15.87, 43.98 -1.21
BXD16 m 98.07 49.776   5 22.26 0.5076 47.1, 177.8 -0.04
BXD2 m 107.8 46.182   5 20.653 0.4285 44.58, 152.9 0.12
BXD27 m 113.4 38.03   4 19.015 0.3352 87.9, 169.7 0.21
BXD32 m 157.8 4.2194   3 2.4361 0.0267 155.2, 162.7 0.93
BXD34 m 42.994 35.605   5 15.923 0.8281 13.84, 103.0 -0.93
BXD39 m 181.6 34.964   5 15.636 0.1925 127.4, 219.0 1.31
BXD40 m 18.175 4.9311   4 2.4656 0.2713 11.1, 21.6 -1.33
BXD43 m 26.69 6.042   3 3.4884 0.2264 20.88, 32.94 -1.19
BXD44 m 120.3 50.53   6 20.627 0.4202 52.96, 170.6 0.32
BXD45 m 97.54 32.113   4 16.057 0.3292 66.32, 136.6 -0.05
BXD48 m 105.5 23.335   3 13.472 0.2213 80.36, 126.5 0.08
BXD48a m 331.1 22.815   3 13.172 0.0689 311.2, 356.0 3.72
BXD49 m 54.24 36.611   3 21.137 0.6749 27.65, 96.0 -0.75
BXD50 m 122.0 48.044   5 21.486 0.3937 50.33, 171.6 0.35
BXD51 m 82.79 19.311   4 9.6557 0.2333 65.91, 109.9 -0.29
BXD53 m 52.97 17.455   5 7.806 0.3295 25.95, 71.18 -0.77
BXD55 m 45.962 10.969   4 5.4847 0.2387 37.97, 61.95 -0.88
BXD56 m 58.92 5.1777   4 2.5888 0.0879 51.42, 62.5 -0.67
BXD6 m 65.65 35.003   5 15.654 0.5331 17.72, 113.5 -0.56
BXD60 m 176.6 10.407   5 4.654 0.0589 161.0, 190.0 1.23
BXD61 m 263.5 70.63   5 31.588 0.2681 142.2, 326.5 2.63
BXD62 m 103.1 39.665   3 22.9 0.3849 68.99, 146.6 0.04
BXD63 m 100.2 6.2532   4 3.1266 0.0624 96.17, 109.5 0.0
BXD64 m 28.34 13.491   3 7.789 0.476 13.16, 38.96 -1.16
BXD65 m 156.4 10.536   2   7.45 0.0673 149.0, 163.9 0.9
BXD65a m 120.6 23.708   4 11.854 0.1967 92.83, 145.1 0.33
BXD66 m 215.6 73.63   4 36.813 0.3415 127.4, 284.7 1.86
BXD67 m 48.766 14.377   5 6.4295 0.2948 35.78, 72.45 -0.83
BXD68 m 25.33 11.973   4 5.9863 0.4727 8.858, 34.46 -1.21
BXD69 m 48.51 16.927   3 9.7728 0.3489 31.87, 65.71 -0.84
BXD70 m 104.8 42.39   3 24.474 0.4046 63.62, 148.3 0.07
BXD71 m 72.15 25.594   3 14.776 0.3547 57.02, 101.7 -0.46
BXD73 m 82.66 23.006   4 11.503 0.2783 62.03, 113.4 -0.29
BXD73a m 141.5 72.35   4 36.174 0.5113 56.48, 233.4 0.66
BXD73b m 70.85 18.677   5 8.3527 0.2636 53.95, 102.5 -0.48
BXD75 m 172.1 58.07   5 25.97 0.3375 106.8, 249.2 1.16
BXD77 m 101.3 38.82   5 17.361 0.3834 46.4, 139.2 0.01
BXD79 m 70.73 21.175   5 9.4699 0.2994 43.95, 91.97 -0.48
BXD8 m 19.969 9.7063   5 4.3408 0.4861 8.593, 32.3 -1.3
BXD81 m 118.9 4.9   3 2.829 0.0412 114.0, 123.8 0.3
BXD83 m 205.7 65.11   4 32.554 0.3166 111.5, 250.1 1.7
BXD84 m 61.58 14.167   3 8.1794 0.23 48.13, 76.37 -0.63
BXD85 m 68.87 29.282   4 14.641 0.4252 49.22, 112.4 -0.51
BXD87 m 100.5 6.7541   5 3.0205 0.0672 89.53, 107.2 0.0
BXD89 m 93.66 40.033   4 20.016 0.4274 34.94, 120.5 -0.11
BXD90 m 59.25 16.004   4 8.0019 0.2701 45.23, 79.27 -0.66
BXD95 m 98.02 35.756   5 15.99 0.3648 45.24, 144.2 -0.04
BXD98 m 56.81 12.687   4 6.3437 0.2233 45.47, 74.78 -0.7
BXD99 m 63.87 6.8738   5 3.074 0.1076 55.2, 70.53 -0.59
C57BL/6J m 127.2 20.395   4 10.197 0.1604 107.6, 155.1 0.43
DBA/2J m 192.7 44.862   4 22.431 0.2328 135.2, 231.1 1.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 33.72 15.8121327286 64.9233605339 2.5166394661
BXD100 m 129.266 15.8121327286 160.4693605339 98.0626394661
BXD101 m 99.52 17.6785018252 134.4064176401 64.6335823599
BXD11 m 84.042 15.8121327286 115.2453605339 52.8386394661
BXD12 m 25.488 15.8121327286 56.6913605339 -5.7153605339
BXD16 m 98.07 15.8121327286 129.2733605339 66.8666394661
BXD2 m 107.768 15.8121327286 138.9713605339 76.5646394661
BXD27 m 113.445 17.6785018252 148.3314176401 78.5585823599
BXD32 m 157.8333333333 20.4133755753 198.1166985644 117.5499681022
BXD34 m 42.994 15.8121327286 74.1973605339 11.7906394661
BXD39 m 181.6 15.8121327286 212.8033605339 150.3966394661
BXD40 m 18.175 17.6785018252 53.0614176401 -16.7114176401
BXD43 m 26.69 20.4133755753 66.9733652311 -13.5933652311
BXD44 m 120.2533333333 14.4344362962 148.7379740573 91.7686926094
BXD45 m 97.5425 17.6785018252 132.4289176401 62.6560823599
BXD48 m 105.4533333333 20.4133755753 145.7366985644 65.1699681022
BXD48a m 331.1 20.4133755753 371.3833652311 290.8166347689
BXD49 m 54.2433333333 20.4133755753 94.5266985644 13.9599681022
BXD50 m 122.046 15.8121327286 153.2493605339 90.8426394661
BXD51 m 82.7875 17.6785018252 117.6739176401 47.9010823599
BXD53 m 52.966 15.8121327286 84.1693605339 21.7626394661
BXD55 m 45.9625 17.6785018252 80.8489176401 11.0760823599
BXD56 m 58.915 17.6785018252 93.8014176401 24.0285823599
BXD6 m 65.654 15.8121327286 96.8573605339 34.4506394661
BXD60 m 176.6 15.8121327286 207.8033605339 145.3966394661
BXD61 m 263.46 15.8121327286 294.6633605339 232.2566394661
BXD62 m 103.0533333333 20.4133755753 143.3366985644 62.7699681022
BXD63 m 100.17 17.6785018252 135.0564176401 65.2835823599
BXD64 m 28.34 20.4133755753 68.6233652311 -11.9433652311
BXD65 m 156.45 25.0011770437 205.7868449692 107.1131550308
BXD65a m 120.5575 17.6785018252 155.4439176401 85.6710823599
BXD66 m 215.575 17.6785018252 250.4614176401 180.6885823599
BXD67 m 48.766 15.8121327286 79.9693605339 17.5626394661
BXD68 m 25.3295 17.6785018252 60.2159176401 -9.5569176401
BXD69 m 48.51 20.4133755753 88.7933652311 8.2266347689
BXD70 m 104.7733333333 20.4133755753 145.0566985644 64.4899681022
BXD71 m 72.15 20.4133755753 112.4333652311 31.8666347689
BXD73 m 82.66 17.6785018252 117.5464176401 47.7735823599
BXD73a m 141.495 17.6785018252 176.3814176401 106.6085823599
BXD73b m 70.854 15.8121327286 102.0573605339 39.6506394661
BXD75 m 172.06 15.8121327286 203.2633605339 140.8566394661
BXD77 m 101.26 15.8121327286 132.4633605339 70.0566394661
BXD79 m 70.73 15.8121327286 101.9333605339 39.5266394661
BXD8 m 19.9686 15.8121327286 51.1719605339 -11.2347605339
BXD81 m 118.9 20.4133755753 159.1833652311 78.6166347689
BXD83 m 205.675 17.6785018252 240.5614176401 170.7885823599
BXD84 m 61.5833333333 20.4133755753 101.8666985644 21.2999681022
BXD85 m 68.87 17.6785018252 103.7564176401 33.9835823599
BXD87 m 100.464 15.8121327286 131.6673605339 69.2606394661
BXD89 m 93.66 17.6785018252 128.5464176401 58.7735823599
BXD90 m 59.2475 17.6785018252 94.1339176401 24.3610823599
BXD95 m 98.018 15.8121327286 129.2213605339 66.8146394661
BXD98 m 56.815 17.6785018252 91.7014176401 21.9285823599
BXD99 m 63.872 15.8121327286 95.0753605339 32.6686394661
C57BL/6J m 127.175 17.6785018252 162.0614176401 92.2885823599
DBA/2J m 192.675 17.6785018252 227.5614176401 157.7885823599




  GWAS USING LINEAR MIXED MODELS

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