Project measure / variable:   Auwerx1   ogtt_ins_auc_CD

ID, description, units MPD:111270   ogtt_ins_auc_CD   insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast)   [AUC]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure hormone quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx1 - insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast) CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means40.339   AUC
Median of the strain means33.68   AUC
SD of the strain means± 28.104
Coefficient of variation (CV)0.6967
Min–max range of strain means6.535   –   153.6   AUC
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 183758.9286 3281.4094 9.4053 < 0.0001
Residuals 182 63497.7416 348.8887


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 16.66 2.5472   5 1.1391 0.1529 13.8, 19.4 -0.84
BXD100 m 43.096 38.101   3 21.997 0.8841 9.068, 84.26 0.1
BXD101 m 20.633 5.1307   4 2.5653 0.2487 13.65, 26.01 -0.7
BXD11 m 11.443 16.265   4 8.1326 1.4214 0.2417, 35.5 -1.03
BXD12 m 16.108 2.5176   5 1.1259 0.1563 13.72, 19.88 -0.86
BXD16 m 70.24 25.566   4 12.783 0.364 34.43, 89.7 1.06
BXD2 m 33.68 15.65   4 7.825 0.4647 17.61, 49.13 -0.24
BXD27 m 79.72 14.304   4 7.1519 0.1794 64.94, 98.51 1.4
BXD32 m 18.9 16.298   5 7.2886 0.8623 4.1, 45.9 -0.76
BXD34 m 39.82 15.798   4 7.899 0.3967 25.78, 61.7 -0.02
BXD39 m 90.46 35.803   5 16.012 0.3958 70.13, 153.4 1.78
BXD40 m 12.75 7.5813   4 3.7907 0.5946 4.3, 22.5 -0.98
BXD43 m 16.61 15.273   4 7.6367 0.9195 4.98, 38.68 -0.84
BXD44 m 34.28 15.006   7 5.6717 0.4377 15.3, 57.21 -0.22
BXD45 m 28.095 8.6917   4 4.3458 0.3094 16.53, 36.74 -0.44
BXD48 m 29.863 14.735   3 8.5072 0.4934 17.41, 46.13 -0.37
BXD48a m 73.06 28.141   5 12.585 0.3852 27.14, 101.9 1.16
BXD49 m 13.03 4.0665   3 2.3478 0.3121 8.37, 15.86 -0.97
BXD50 m 48.017 18.175   4 9.0874 0.3785 23.46, 66.13 0.27
BXD51 m 29.898 1.8237   4 0.91184 0.061 27.55, 32.0 -0.37
BXD53 m 12.677 10.287   5 4.6003 0.8114 2.475, 29.33 -0.98
BXD55 m 41.034 16.07   5 7.1867 0.3916 29.75, 67.12 0.02
BXD56 m 20.914 10.409   5 4.6552 0.4977 6.628, 31.91 -0.69
BXD6 m 21.452 2.3521   5 1.0519 0.1096 18.38, 24.68 -0.67
BXD60 m 47.03 15.962   3 9.2158 0.3394 29.89, 61.47 0.24
BXD61 m 28.84 10.416   3 6.0136 0.3612 17.66, 38.27 -0.41
BXD62 m 22.38 7.4402   4 3.7201 0.3324 16.94, 32.9 -0.64
BXD63 m 44.3 11.763   4 5.8814 0.2655 33.91, 57.05 0.14
BXD64 m 25.42 16.938   3 9.7791 0.6663 9.63, 43.31 -0.53
BXD65 m 79.25 6.8938   3 3.9801 0.087 72.82, 86.53 1.38
BXD65a m 91.99 18.187   5 8.1333 0.1977 74.24, 115.4 1.84
BXD65b m 54.72 14.703   4 7.3514 0.2687 33.99, 66.88 0.51
BXD66 m 153.6 72.77   4 36.384 0.4736 61.58, 238.0 4.03
BXD67 m 24.991 27.791   5 12.428 1.112 2.325, 71.7 -0.55
BXD68 m 25.386 15.183   5 6.79 0.5981 5.25, 44.11 -0.53
BXD69 m 44.538 6.8198   5 3.0499 0.1531 33.98, 52.52 0.15
BXD70 m 50.16 9.1077   3 5.2583 0.1816 43.37, 60.51 0.35
BXD71 m 34.29 17.96   5 8.0322 0.5238 16.47, 60.62 -0.22
BXD73 m 49.133 11.338   3 6.5459 0.2308 39.17, 61.47 0.31
BXD73a m 121.7 30.846   4 15.423 0.2534 85.11, 160.6 2.9
BXD73b m 44.87 10.644   5 4.7602 0.2372 33.41, 57.64 0.16
BXD75 m 68.33 17.938   5 8.022 0.2625 45.53, 85.1 1.0
BXD77 m 25.92 14.737   5 6.5906 0.5686 13.6, 49.2 -0.51
BXD79 m 45.107 21.911   3 12.65 0.4858 22.25, 65.93 0.17
BXD8 m 6.535 4.831   2   3.416 0.7392 3.119, 9.951 -1.2
BXD81 m 22.483 2.8636   3 1.6533 0.1274 20.1, 25.66 -0.64
BXD83 m 35.75 13.352   3 7.7088 0.3735 21.77, 48.37 -0.16
BXD84 m 23.558 7.3471   5 3.2857 0.3119 15.86, 33.3 -0.6
BXD85 m 52.89 5.9867   5 2.6773 0.1132 47.38, 63.02 0.45
BXD87 m 28.96 8.6081   5 3.8497 0.2972 21.82, 41.3 -0.4
BXD89 m 37.22 13.147   4 6.5737 0.3532 25.22, 55.55 -0.11
BXD90 m 7.4345 5.426   4 2.713 0.7298 0.195, 13.32 -1.17
BXD95 m 24.725 20.005   4 10.002 0.8091 12.47, 54.63 -0.56
BXD98 m 12.559 6.0797   5 2.7189 0.4841 5.507, 20.36 -0.99
BXD99 m 33.562 4.4293   5 1.9809 0.132 28.97, 40.96 -0.24
C57BL/6J m 40.932 14.772   4 7.3861 0.3609 23.33, 56.69 0.02
DBA/2J m 68.33 38.799   4 19.4 0.5678 35.57, 124.6 1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 16.66 8.353307012 33.1417770584 0.1782229416
BXD100 m 43.096 10.7840729811 64.3738826878 21.8181173122
BXD101 m 20.6325 9.3392811579 39.0596869463 2.2053130537
BXD11 m 11.442925 9.3392811579 29.8701119463 -6.9842619463
BXD12 m 16.108 8.353307012 32.5897770584 -0.3737770584
BXD16 m 70.24 9.3392811579 88.6671869463 51.8128130537
BXD2 m 33.68 9.3392811579 52.1071869463 15.2528130537
BXD27 m 79.7225 9.3392811579 98.1496869463 61.2953130537
BXD32 m 18.9 8.353307012 35.3817770584 2.4182229416
BXD34 m 39.82 9.3392811579 58.2471869463 21.3928130537
BXD39 m 90.456 8.353307012 106.9377770584 73.9742229416
BXD40 m 12.75 9.3392811579 31.1771869463 -5.6771869463
BXD43 m 16.61 9.3392811579 35.0371869463 -1.8171869463
BXD44 m 34.28 7.0598329622 48.2096440064 20.3503559936
BXD45 m 28.095 9.3392811579 46.5221869463 9.6678130537
BXD48 m 29.8633333333 10.7840729811 51.1412160211 8.5854506456
BXD48a m 73.06 8.353307012 89.5417770584 56.5782229416
BXD49 m 13.03 10.7840729811 34.3078826878 -8.2478826878
BXD50 m 48.0175 9.3392811579 66.4446869463 29.5903130537
BXD51 m 29.8975 9.3392811579 48.3246869463 11.4703130537
BXD53 m 12.677 8.353307012 29.1587770584 -3.8047770584
BXD55 m 41.034 8.353307012 57.5157770584 24.5522229416
BXD56 m 20.9136 8.353307012 37.3953770584 4.4318229416
BXD6 m 21.452 8.353307012 37.9337770584 4.9702229416
BXD60 m 47.03 10.7840729811 68.3078826878 25.7521173122
BXD61 m 28.84 10.7840729811 50.1178826878 7.5621173122
BXD62 m 22.38 9.3392811579 40.8071869463 3.9528130537
BXD63 m 44.3 9.3392811579 62.7271869463 25.8728130537
BXD64 m 25.42 10.7840729811 46.6978826878 4.1421173122
BXD65 m 79.2533333333 10.7840729811 100.5312160211 57.9754506456
BXD65a m 91.992 8.353307012 108.4737770584 75.5102229416
BXD65b m 54.7175 9.3392811579 73.1446869463 36.2903130537
BXD66 m 153.645 9.3392811579 172.0721869463 135.2178130537
BXD67 m 24.991 8.353307012 41.4727770584 8.5092229416
BXD68 m 25.386 8.353307012 41.8677770584 8.9042229416
BXD69 m 44.538 8.353307012 61.0197770584 28.0562229416
BXD70 m 50.16 10.7840729811 71.4378826878 28.8821173122
BXD71 m 34.29 8.353307012 50.7717770584 17.8082229416
BXD73 m 49.1333333333 10.7840729811 70.4112160211 27.8554506456
BXD73a m 121.7275 9.3392811579 140.1546869463 103.3003130537
BXD73b m 44.87 8.353307012 61.3517770584 28.3882229416
BXD75 m 68.328 8.353307012 84.8097770584 51.8462229416
BXD77 m 25.92 8.353307012 42.4017770584 9.4382229416
BXD79 m 45.1066666667 10.7840729811 66.3845493544 23.8287839789
BXD8 m 6.535 13.2077380763 32.5949776959 -19.5249776959
BXD81 m 22.4833333333 10.7840729811 43.7612160211 1.2054506456
BXD83 m 35.75 10.7840729811 57.0278826878 14.4721173122
BXD84 m 23.558 8.353307012 40.0397770584 7.0762229416
BXD85 m 52.886 8.353307012 69.3677770584 36.4042229416
BXD87 m 28.96 8.353307012 45.4417770584 12.4782229416
BXD89 m 37.22 9.3392811579 55.6471869463 18.7928130537
BXD90 m 7.4345 9.3392811579 25.8616869463 -10.9926869463
BXD95 m 24.725 9.3392811579 43.1521869463 6.2978130537
BXD98 m 12.559 8.353307012 29.0407770584 -3.9227770584
BXD99 m 33.562 8.353307012 50.0437770584 17.0802229416
C57BL/6J m 40.9325 9.3392811579 59.3596869463 22.5053130537
DBA/2J m 68.335 9.3392811579 86.7621869463 49.9078130537




  GWAS USING LINEAR MIXED MODELS