Project measure / variable:   Auwerx1   ogtt_ins_t15_CD

ID, description, units MPD:111266   ogtt_ins_t15_CD   insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min   [µg/L]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure hormone quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx1 - insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means1.699   µg/L
Median of the strain means1.307   µg/L
SD of the strain means± 1.1903
Coefficient of variation (CV)0.7006
Min–max range of strain means0.395   –   6.9893   µg/L
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 337.5613 6.0279 6.6986 < 0.0001
Residuals 192 172.7765 0.8999


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.724 0.14536   5 0.06501 0.2008 0.51, 0.86 -0.82
BXD100 m 1.6793 2.0866   3 1.2047 1.2425 0.139, 4.054 -0.02
BXD101 m 0.895 0.26451   4 0.13226 0.2955 0.57, 1.21 -0.68
BXD11 m 0.59803 0.81203   4 0.40602 1.3579 0.01612, 1.7851 -0.92
BXD12 m 0.8918 0.13873   5 0.06204 0.1556 0.736, 1.038 -0.68
BXD16 m 3.0682 1.339   4 0.66949 0.4364 1.4251, 4.5345 1.15
BXD2 m 1.5937 0.86099   4 0.4305 0.5402 0.56568, 2.4528 -0.09
BXD27 m 3.0671 0.50628   4 0.25314 0.1651 2.5408, 3.5459 1.15
BXD32 m 0.838 0.70595   5 0.31571 0.8424 0.18, 1.85 -0.72
BXD34 m 1.9002 0.78747   4 0.39374 0.4144 1.152, 2.989 0.17
BXD39 m 4.3842 1.8175   5 0.8128 0.4146 2.9295, 7.4614 2.26
BXD40 m 0.7175 0.55072   4 0.27536 0.7676 0.12, 1.45 -0.82
BXD43 m 0.76975 0.5627   4 0.28135 0.731 0.305, 1.578 -0.78
BXD44 m 1.2408 0.32091   8 0.11346 0.2586 0.72, 1.604 -0.38
BXD45 m 0.88925 0.27105   4 0.13552 0.3048 0.552, 1.14 -0.68
BXD48 m 1.307 0.47383   4 0.23691 0.3625 0.755, 1.912 -0.33
BXD48a m 3.5046 1.5523   5 0.69423 0.4429 1.079, 4.862 1.52
BXD49 m 0.795 0.25848   4 0.12924 0.3251 0.46, 1.09 -0.76
BXD50 m 2.0735 0.89353   4 0.44677 0.4309 0.865, 2.759 0.31
BXD51 m 1.0913 0.04809   4 0.02405 0.0441 1.044, 1.151 -0.51
BXD53 m 0.67402 0.49904   5 0.22318 0.7404 0.13669, 1.4035 -0.86
BXD55 m 1.0912 0.4205   5 0.18805 0.3854 0.818, 1.802 -0.51
BXD56 m 0.87206 0.36086   5 0.16138 0.4138 0.3313, 1.157 -0.69
BXD6 m 0.89675 0.09019   5 0.04033 0.1006 0.79689, 1.0272 -0.67
BXD60 m 1.7612 1.1214   4 0.56069 0.6367 0.373, 3.0 0.05
BXD61 m 1.0623 0.19244   3 0.11111 0.1812 0.938, 1.284 -0.53
BXD62 m 1.3642 0.60178   4 0.30089 0.4411 0.863, 2.163 -0.28
BXD63 m 1.7872 0.46469   5 0.20781 0.26 1.19, 2.32 0.07
BXD64 m 1.072 0.82273   3 0.475 0.7675 0.27, 1.914 -0.53
BXD65 m 3.06 0.49187   3 0.28398 0.1607 2.518, 3.478 1.14
BXD65a m 3.7666 1.0821   5 0.48391 0.2873 2.89, 5.58 1.74
BXD65b m 1.9067 0.74619   4 0.3731 0.3913 1.054, 2.556 0.17
BXD66 m 6.9893 4.0371   4 2.0186 0.5776 2.065, 11.883 4.44
BXD67 m 1.2279 1.328   5 0.59389 1.0815 0.12376, 3.4464 -0.4
BXD68 m 1.2442 0.76839   5 0.34364 0.6176 0.35, 2.4 -0.38
BXD69 m 1.6984 0.48234   5 0.21571 0.284 1.01, 2.319 0.0
BXD70 m 2.597 0.87895   4 0.43947 0.3384 1.792, 3.836 0.75
BXD71 m 1.0978 0.53919   5 0.24113 0.4912 0.527, 1.716 -0.51
BXD73 m 1.8978 0.70222   4 0.35111 0.37 1.163, 2.8 0.17
BXD73a m 4.593 1.5443   4 0.77217 0.3362 3.112, 6.745 2.43
BXD73b m 1.7078 0.515   5 0.23032 0.3016 1.194, 2.507 0.01
BXD75 m 2.9756 0.93783   5 0.41941 0.3152 1.786, 3.937 1.07
BXD77 m 1.292 0.68885   5 0.30806 0.5332 0.75, 2.43 -0.34
BXD79 m 1.918 0.72033   5 0.32214 0.3756 0.79, 2.68 0.18
BXD8 m 0.43566 0.32207   2   0.22773 0.7393 0.20792, 0.66339 -1.06
BXD81 m 0.95025 0.18218   4 0.09109 0.1917 0.684, 1.068 -0.63
BXD83 m 1.7777 0.75558   3 0.43623 0.425 0.911, 2.298 0.07
BXD84 m 0.9452 0.30068   5 0.13447 0.3181 0.653, 1.351 -0.63
BXD85 m 2.0616 0.3699   5 0.16543 0.1794 1.743, 2.647 0.3
BXD87 m 0.834 0.16238   5 0.07262 0.1947 0.662, 1.062 -0.73
BXD89 m 1.822 0.68413   4 0.34207 0.3755 1.202, 2.789 0.1
BXD90 m 0.395 0.36295   4 0.18147 0.9189 0.013, 0.888 -1.1
BXD95 m 1.1412 0.80003   4 0.40002 0.701 0.637, 2.336 -0.47
BXD98 m 0.6006 0.28499   5 0.12745 0.4745 0.239, 0.93 -0.92
BXD99 m 1.4468 0.32556   5 0.1456 0.225 0.991, 1.862 -0.21
C57BL/6J m 1.9992 0.7995   4 0.39975 0.3999 0.953, 2.807 0.25
DBA/2J m 1.8523 2.2852   4 1.1426 1.2337 0.508, 5.272 0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.724 0.424235238 1.560760095 -0.112760095
BXD100 m 1.6793333333 0.5476853373 2.7595859709 0.5990806958
BXD101 m 0.895 0.4743094153 1.8305262266 -0.0405262266
BXD11 m 0.598025 0.4743094153 1.5335512266 -0.3375012266
BXD12 m 0.8918 0.424235238 1.728560095 0.055039905
BXD16 m 3.0682 0.4743094153 4.0037262266 2.1326737734
BXD2 m 1.59372 0.4743094153 2.5292462266 0.6581937734
BXD27 m 3.06715 0.4743094153 4.0026762266 2.1316237734
BXD32 m 0.838 0.424235238 1.674760095 0.001239905
BXD34 m 1.90025 0.4743094153 2.8357762266 0.9647237734
BXD39 m 4.3842 0.424235238 5.220960095 3.547439905
BXD40 m 0.7175 0.4743094153 1.6530262266 -0.2180262266
BXD43 m 0.76975 0.4743094153 1.7052762266 -0.1657762266
BXD44 m 1.24075 0.335387404 1.9022669388 0.5792330612
BXD45 m 0.88925 0.4743094153 1.8247762266 -0.0462762266
BXD48 m 1.307 0.4743094153 2.2425262266 0.3714737734
BXD48a m 3.5046 0.424235238 4.341360095 2.667839905
BXD49 m 0.795 0.4743094153 1.7305262266 -0.1405262266
BXD50 m 2.0735 0.4743094153 3.0090262266 1.1379737734
BXD51 m 1.09125 0.4743094153 2.0267762266 0.1557237734
BXD53 m 0.674018 0.424235238 1.510778095 -0.162742095
BXD55 m 1.0912 0.424235238 1.927960095 0.254439905
BXD56 m 0.87206 0.424235238 1.708820095 0.035299905
BXD6 m 0.896754 0.424235238 1.733514095 0.059993905
BXD60 m 1.76125 0.4743094153 2.6967762266 0.8257237734
BXD61 m 1.0623333333 0.5476853373 2.1425859709 -0.0179193042
BXD62 m 1.36425 0.4743094153 2.2997762266 0.4287237734
BXD63 m 1.7872 0.424235238 2.623960095 0.950439905
BXD64 m 1.072 0.5476853373 2.1522526376 -0.0082526376
BXD65 m 3.06 0.5476853373 4.1402526376 1.9797473624
BXD65a m 3.7666 0.424235238 4.603360095 2.929839905
BXD65b m 1.90675 0.4743094153 2.8422762266 0.9712237734
BXD66 m 6.98925 0.4743094153 7.9247762266 6.0537237734
BXD67 m 1.22788 0.424235238 2.064640095 0.391119905
BXD68 m 1.2442 0.424235238 2.080960095 0.407439905
BXD69 m 1.6984 0.424235238 2.535160095 0.861639905
BXD70 m 2.597 0.4743094153 3.5325262266 1.6614737734
BXD71 m 1.0978 0.424235238 1.934560095 0.261039905
BXD73 m 1.89775 0.4743094153 2.8332762266 0.9622237734
BXD73a m 4.593 0.4743094153 5.5285262266 3.6574737734
BXD73b m 1.7078 0.424235238 2.544560095 0.871039905
BXD75 m 2.9756 0.424235238 3.812360095 2.138839905
BXD77 m 1.292 0.424235238 2.128760095 0.455239905
BXD79 m 1.918 0.424235238 2.754760095 1.081239905
BXD8 m 0.435655 0.6707748079 1.7586888776 -0.8873788776
BXD81 m 0.95025 0.4743094153 1.8857762266 0.0147237734
BXD83 m 1.7776666667 0.5476853373 2.8579193042 0.6974140291
BXD84 m 0.9452 0.424235238 1.781960095 0.108439905
BXD85 m 2.0616 0.424235238 2.898360095 1.224839905
BXD87 m 0.834 0.424235238 1.670760095 -0.002760095
BXD89 m 1.822 0.4743094153 2.7575262266 0.8864737734
BXD90 m 0.395 0.4743094153 1.3305262266 -0.5405262266
BXD95 m 1.14125 0.4743094153 2.0767762266 0.2057237734
BXD98 m 0.6006 0.424235238 1.437360095 -0.236160095
BXD99 m 1.4468 0.424235238 2.283560095 0.610039905
C57BL/6J m 1.99925 0.4743094153 2.9347762266 1.0637237734
DBA/2J m 1.85225 0.4743094153 2.7877762266 0.9167237734




  GWAS USING LINEAR MIXED MODELS