Project measure / variable:   Auwerx1   ogtt_gluc_auc_CD

ID, description, units MPD:111262   ogtt_gluc_auc_CD   glucose, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast)   [AUC]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast) CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means36846.0   AUC
Median of the strain means33566.0   AUC
SD of the strain means± 10928.0
Coefficient of variation (CV)0.2966
Min–max range of strain means22298.0   –   78778.0   AUC
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 35815939800.7123 639570353.5841 17.0027 < 0.0001
Residuals 199 7485552970.7722 37615844.0742


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 27771.0 2123.0   5 949.4 0.0764 25208.0, 30900.0 -0.83
BXD100 m 47073.0 6017.0   3 3474.0 0.1278 40140.0, 50940.0 0.94
BXD101 m 35419.0 1657.0   4 828.7 0.0468 33630.0, 37643.0 -0.13
BXD11 m 31127.0 9692.0   4 4846.0 0.3114 18758.0, 42158.0 -0.52
BXD12 m 26904.0 1750.0   5 782.5 0.065 23970.0, 28568.0 -0.91
BXD16 m 47331.0 11438.0   4 5719.0 0.2417 31763.0, 58703.0 0.96
BXD2 m 30302.0 698.1   4 349.0 0.023 29303.0, 30930.0 -0.6
BXD27 m 54243.0 9370.0   5 4190.0 0.1727 44243.0, 65843.0 1.59
BXD32 m 29934.0 1543.0   5 690.2 0.0516 28283.0, 32393.0 -0.63
BXD34 m 43101.0 6736.0   4 3368.0 0.1563 33930.0, 50010.0 0.57
BXD39 m 52077.0 5863.0   5 2622.0 0.1126 45630.0, 58448.0 1.39
BXD40 m 32404.0 3836.0   4 1918.0 0.1184 28905.0, 37845.0 -0.41
BXD43 m 45148.0 3950.0   4 1975.0 0.0875 39360.0, 48105.0 0.76
BXD44 m 70840.0 11677.0   9 3892.0 0.1648 56078.0, 90218.0 3.11
BXD45 m 35661.0 723.0   4 361.5 0.0203 35040.0, 36473.0 -0.11
BXD48 m 36358.0 4027.0   4 2013.0 0.1107 32025.0, 40508.0 -0.04
BXD48a m 38964.0 4532.0   5 2027.0 0.1163 33210.0, 43943.0 0.19
BXD49 m 33064.0 1645.0   4 822.6 0.0498 31208.0, 34710.0 -0.35
BXD50 m 37750.0 5082.0   4 2541.0 0.1346 31080.0, 42615.0 0.08
BXD51 m 29130.0 1151.0   4 575.4 0.0395 27765.0, 30458.0 -0.71
BXD53 m 29754.0 3807.0   5 1703.0 0.1279 24825.0, 34268.0 -0.65
BXD55 m 26000.0 2116.0   5 946.2 0.0814 23655.0, 29040.0 -0.99
BXD56 m 38051.0 10370.0   5 4638.0 0.2725 28575.0, 53820.0 0.11
BXD6 m 30773.0 3337.0   5 1493.0 0.1085 28350.0, 35865.0 -0.56
BXD60 m 29195.0 7614.0   5 3405.0 0.2608 16545.0, 36683.0 -0.7
BXD61 m 28140.0 2217.0   3 1280.0 0.0788 25658.0, 29925.0 -0.8
BXD62 m 28390.0 2714.0   4 1357.0 0.0956 25830.0, 32228.0 -0.77
BXD63 m 48596.0 3735.0   5 1670.0 0.0769 46253.0, 55185.0 1.08
BXD64 m 38095.0 8929.0   4 4465.0 0.2344 29318.0, 50558.0 0.11
BXD65 m 44016.0 8800.0   4 4400.0 0.1999 34410.0, 55710.0 0.66
BXD65a m 51219.0 17215.0   5 7699.0 0.3361 40650.0, 81585.0 1.32
BXD65b m 40575.0 4465.0   4 2233.0 0.1101 36585.0, 45735.0 0.34
BXD66 m 29202.0 3399.0   4 1699.0 0.1164 24713.0, 32093.0 -0.7
BXD67 m 33296.0 3685.0   5 1648.0 0.1107 29513.0, 38505.0 -0.32
BXD68 m 39899.0 5942.0   5 2658.0 0.1489 32288.0, 46148.0 0.28
BXD69 m 78778.0 11846.0   5 5298.0 0.1504 65858.0, 93165.0 3.84
BXD70 m 22663.0 5912.0   4 2956.0 0.2609 15210.0, 29663.0 -1.3
BXD71 m 43011.0 1996.0   5 892.5 0.0464 40613.0, 45743.0 0.56
BXD73 m 33566.0 1750.0   4 875.1 0.0521 31898.0, 35483.0 -0.3
BXD73a m 34553.0 1736.0   4 868.0 0.0502 32625.0, 36488.0 -0.21
BXD73b m 41913.0 3512.0   5 1570.0 0.0838 37058.0, 44858.0 0.46
BXD75 m 31779.0 3566.0   5 1595.0 0.1122 28613.0, 37103.0 -0.46
BXD77 m 36650.0 4005.0   5 1791.0 0.1093 33270.0, 43545.0 -0.02
BXD79 m 31235.0 4113.0   5 1839.0 0.1317 25433.0, 34995.0 -0.51
BXD8 m 26286.0 4270.0   4 2135.0 0.1624 20595.0, 30938.0 -0.97
BXD81 m 27156.0 3178.0   4 1589.0 0.117 22823.0, 30113.0 -0.89
BXD83 m 27893.0 1653.0   3 954.5 0.0593 26160.0, 29453.0 -0.82
BXD84 m 37191.0 3516.0   5 1573.0 0.0945 33390.0, 42218.0 0.03
BXD85 m 55989.0 7734.0   5 3459.0 0.1381 45008.0, 65445.0 1.75
BXD87 m 31361.0 3310.0   5 1480.0 0.1056 26273.0, 35520.0 -0.5
BXD89 m 25616.0 880.7   4 440.3 0.0344 24945.0, 26873.0 -1.03
BXD90 m 26027.0 2465.0   4 1232.0 0.0947 23370.0, 29070.0 -0.99
BXD95 m 36716.0 4869.0   4 2435.0 0.1326 33645.0, 43928.0 -0.01
BXD98 m 45876.0 7816.0   5 3495.0 0.1704 36885.0, 58073.0 0.83
BXD99 m 32448.0 4391.0   5 1964.0 0.1353 27300.0, 37620.0 -0.4
C57BL/6J m 31388.0 3224.0   4 1612.0 0.1027 27983.0, 35745.0 -0.5
DBA/2J m 22298.0 3827.0   4 1914.0 0.1716 17955.0, 26078.0 -1.33


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 27771.2 2742.8395532452 33179.9604068545 22362.4395931455
BXD100 m 47072.6666666669 3540.9906370126 54055.3463264581 40089.9870068757
BXD101 m 35419.0000000004 3066.5878462157 41466.1779718683 29371.8220281324
BXD11 m 31127.2500000001 3066.5878462157 37174.4279718681 25080.0720281321
BXD12 m 26904.4000000001 2742.8395532452 32313.1604068545 21495.6395931456
BXD16 m 47331.0000000001 3066.5878462157 53378.1779718681 41283.8220281321
BXD2 m 30302.25 3066.5878462158 36349.4279718681 24255.072028132
BXD27 m 54243.4000000002 2742.8395532452 59652.1604068546 48834.6395931457
BXD32 m 29934.4000000001 2742.8395532452 35343.1604068546 24525.6395931456
BXD34 m 43100.75 3066.5878462157 49147.927971868 37053.572028132
BXD39 m 52077.1999999999 2742.8395532452 57485.9604068543 46668.4395931455
BXD40 m 32403.7500000001 3066.5878462158 38450.9279718681 26356.5720281321
BXD43 m 45148.2500000002 3066.5878462158 51195.4279718683 39101.0720281322
BXD44 m 70839.5555555559 2044.3918974772 74871.0075368012 66808.1035743105
BXD45 m 35661.0000000001 3066.5878462157 41708.1779718681 29613.8220281321
BXD48 m 36358.5000000001 3066.5878462157 42405.6779718681 30311.3220281321
BXD48a m 38964.2000000001 2742.8395532452 44372.9604068546 33555.4395931456
BXD49 m 33064.0000000001 3066.5878462157 39111.1779718681 27016.8220281321
BXD50 m 37749.5000000001 3066.5878462158 43796.6779718681 31702.322028132
BXD51 m 29130.2500000002 3066.5878462157 35177.4279718682 23083.0720281323
BXD53 m 29754.2000000001 2742.8395532452 35162.9604068546 24345.4395931457
BXD55 m 25999.8000000001 2742.8395532452 31408.5604068546 20591.0395931457
BXD56 m 38050.8000000001 2742.8395532452 43459.5604068546 32642.0395931456
BXD6 m 30772.8000000001 2742.8395532452 36181.5604068546 25364.0395931456
BXD60 m 29194.8000000002 2742.8395532452 34603.5604068546 23786.0395931457
BXD61 m 28140.3333333335 3540.9906370126 35123.0129931246 21157.6536735424
BXD62 m 28389.75 3066.5878462158 34436.9279718681 22342.572028132
BXD63 m 48595.8000000001 2742.8395532452 54004.5604068546 43187.0395931456
BXD64 m 38094.7500000001 3066.5878462157 44141.927971868 32047.5720281321
BXD65 m 44015.75 3066.5878462157 50062.927971868 37968.572028132
BXD65a m 51219.2000000001 2742.8395532452 56627.9604068546 45810.4395931456
BXD65b m 40575.0000000001 3066.5878462157 46622.1779718681 34527.8220281321
BXD66 m 29201.5000000001 3066.5878462157 35248.6779718681 23154.3220281321
BXD67 m 33295.6000000001 2742.8395532452 38704.3604068546 27886.8395931456
BXD68 m 39899.0000000001 2742.8395532452 45307.7604068546 34490.2395931456
BXD69 m 78778.0000000003 2742.8395532452 84186.7604068548 73369.2395931459
BXD70 m 22663.2500000001 3066.5878462157 28710.4279718681 16616.0720281321
BXD71 m 43011.4000000001 2742.8395532452 48420.1604068545 37602.6395931456
BXD73 m 33566.5000000001 3066.5878462157 39613.6779718681 27519.3220281321
BXD73a m 34552.7500000001 3066.5878462157 40599.9279718681 28505.5720281321
BXD73b m 41913.4000000001 2742.8395532452 47322.1604068546 36504.6395931456
BXD75 m 31779.2000000001 2742.8395532452 37187.9604068546 26370.4395931456
BXD77 m 36649.6000000001 2742.8395532452 42058.3604068546 31240.8395931456
BXD79 m 31234.6000000001 2742.8395532452 36643.3604068546 25825.8395931456
BXD8 m 26286.0000000001 3066.5878462157 32333.1779718681 20238.8220281321
BXD81 m 27156.0000000001 3066.5878462157 33203.1779718681 21108.8220281321
BXD83 m 27892.6666666668 3540.9906370126 34875.3463264579 20909.9870068756
BXD84 m 37191.2000000001 2742.8395532452 42599.9604068546 31782.4395931456
BXD85 m 55989.2000000001 2742.8395532452 61397.9604068545 50580.4395931456
BXD87 m 31360.8000000001 2742.8395532452 36769.5604068546 25952.0395931456
BXD89 m 25616.5000000001 3066.5878462157 31663.6779718681 19569.3220281321
BXD90 m 26027.0000000001 3066.5878462157 32074.1779718681 19979.8220281321
BXD95 m 36716.5000000001 3066.5878462157 42763.6779718681 30669.3220281321
BXD98 m 45876.4000000001 2742.8395532452 51285.1604068546 40467.6395931456
BXD99 m 32448.2000000001 2742.8395532452 37856.9604068546 27039.4395931456
C57BL/6J m 31387.7500000001 3066.5878462157 37434.9279718681 25340.5720281321
DBA/2J m 22297.7500000001 3066.5878462157 28344.9279718681 16250.5720281321




  GWAS USING LINEAR MIXED MODELS