Project measure / variable:   Auwerx1   ogtt_gluc_t180_HFD

ID, description, units MPD:111261   ogtt_gluc_t180_HFD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 180 min   [mg/dL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 180 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means196.9   mg/dL
Median of the strain means174.1   mg/dL
SD of the strain means± 74.77
Coefficient of variation (CV)0.3797
Min–max range of strain means96.4   –   407.4   mg/dL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 1502603.3447 27320.0608 15.6786 < 0.0001
Residuals 192 334561.5222 1742.5079


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 96.4 41.681   5 18.64 0.4324 48.0, 159.0 -1.34
BXD100 m 155.4 31.973   5 14.299 0.2057 121.0, 200.0 -0.56
BXD101 m 147.8 12.42   4 6.2099 0.0841 133.0, 163.0 -0.66
BXD11 m 150.8 39.303   5 17.577 0.2606 122.0, 219.0 -0.62
BXD12 m 117.6 19.92   5 8.9084 0.1694 105.0, 153.0 -1.06
BXD16 m 150.4 9.2898   5 4.1545 0.0618 140.0, 160.0 -0.62
BXD2 m 153.2 36.176   5 16.178 0.2361 101.0, 192.0 -0.58
BXD27 m 197.0 42.119   4 21.059 0.2138 158.0, 249.0 0.0
BXD32 m 168.3 38.188   3 22.048 0.2269 135.0, 210.0 -0.38
BXD34 m 119.8 23.124   5 10.341 0.193 90.0, 147.0 -1.03
BXD39 m 361.6 62.53   5 27.965 0.1729 276.0, 448.0 2.2
BXD40 m 123.0 16.813   4 8.4063 0.1367 105.0, 141.0 -0.99
BXD43 m 154.0 13.748   3 7.9373 0.0893 142.0, 169.0 -0.57
BXD44 m 390.9 66.5   9 22.166 0.1701 232.0, 455.0 2.59
BXD45 m 171.2 10.012   4 5.0062 0.0585 158.0, 179.0 -0.34
BXD48 m 175.2 44.207   4 22.103 0.2523 112.0, 209.0 -0.29
BXD48a m 240.7 69.72   3 40.251 0.2897 168.0, 307.0 0.59
BXD49 m 165.5 44.471   4 22.235 0.2687 128.0, 230.0 -0.42
BXD50 m 156.6 16.592   5 7.4202 0.106 129.0, 171.0 -0.54
BXD51 m 155.2 41.78   4 20.89 0.2691 109.0, 209.0 -0.56
BXD53 m 197.2 50.4   5 22.54 0.2556 150.0, 263.0 0.0
BXD55 m 131.2 18.768   4 9.3842 0.143 112.0, 157.0 -0.88
BXD56 m 188.2 21.975   4 10.988 0.1167 164.0, 216.0 -0.12
BXD6 m 130.6 16.486   5 7.3729 0.1262 106.0, 146.0 -0.89
BXD60 m 198.8 12.637   5 5.6515 0.0636 181.0, 216.0 0.03
BXD61 m 160.6 27.682   5 12.38 0.1724 137.0, 192.0 -0.49
BXD62 m 178.0 47.84   4 23.92 0.2688 144.0, 248.0 -0.25
BXD63 m 281.2 59.22   4 29.612 0.2106 208.0, 350.0 1.13
BXD64 m 340.2 88.84   4 44.421 0.2611 233.0, 450.0 1.92
BXD65 m 208.2 23.599   4 11.8 0.1133 177.0, 233.0 0.15
BXD65a m 178.0 38.721   4 19.361 0.2175 143.0, 213.0 -0.25
BXD66 m 136.2 3.2016   4 1.6008 0.0235 134.0, 141.0 -0.81
BXD67 m 178.8 17.123   5 7.6577 0.0958 161.0, 204.0 -0.24
BXD68 m 125.5 18.193   4 9.0967 0.145 111.0, 151.0 -0.96
BXD69 m 278.2 71.6   5 32.019 0.2574 192.0, 354.0 1.09
BXD70 m 141.5 27.55   4 13.775 0.1947 108.0, 174.0 -0.74
BXD71 m 357.7 112.4   3 64.89 0.3142 228.0, 427.0 2.15
BXD73 m 152.0 15.476   5 6.921 0.1018 129.0, 166.0 -0.6
BXD73a m 173.0 12.437   4 6.2183 0.0719 159.0, 187.0 -0.32
BXD73b m 197.2 25.134   5 11.24 0.1275 169.0, 224.0 0.0
BXD75 m 150.6 24.491   5 10.953 0.1626 122.0, 186.0 -0.62
BXD77 m 205.2 37.185   5 16.629 0.1812 156.0, 254.0 0.11
BXD79 m 292.8 78.62   5 35.162 0.2685 170.0, 367.0 1.28
BXD8 m 140.0 33.705   5 15.073 0.2407 110.0, 197.0 -0.76
BXD81 m 250.0 29.017   4 14.509 0.1161 232.0, 293.0 0.71
BXD83 m 191.2 26.424   4 13.212 0.1382 165.0, 214.0 -0.08
BXD84 m 334.3 25.166   3 14.53 0.0753 311.0, 361.0 1.84
BXD85 m 329.2 70.97   4 35.486 0.2156 247.0, 398.0 1.77
BXD87 m 157.6 13.315   5 5.9548 0.0845 142.0, 178.0 -0.53
BXD89 m 123.2 32.366   4 16.183 0.2626 78.0, 149.0 -0.99
BXD90 m 151.2 15.903   4 7.9517 0.1051 134.0, 172.0 -0.61
BXD95 m 204.8 35.117   5 15.705 0.1715 153.0, 247.0 0.11
BXD98 m 407.4 52.5   5 23.479 0.1289 353.0, 472.0 2.82
BXD99 m 230.2 69.08   5 30.896 0.3001 134.0, 326.0 0.45
C57BL/6J m 196.5 12.069   4 6.0346 0.0614 183.0, 209.0 -0.01
DBA/2J m 180.3 29.67   3 17.13 0.1645 158.0, 214.0 -0.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 96.4 18.6681971719 133.221086601 59.578913399
BXD100 m 155.4 18.6681971719 192.221086601 118.578913399
BXD101 m 147.75 20.8716789468 188.9172263226 106.5827736774
BXD11 m 150.8 18.6681971719 187.621086601 113.978913399
BXD12 m 117.6 18.6681971719 154.421086601 80.778913399
BXD16 m 150.4 18.6681971719 187.221086601 113.578913399
BXD2 m 153.2 18.6681971719 190.021086601 116.378913399
BXD27 m 197.0 20.8716789468 238.1672263226 155.8327736774
BXD32 m 168.3333333333 24.1005389168 215.8691517316 120.797514935
BXD34 m 119.8 18.6681971719 156.621086601 82.978913399
BXD39 m 361.6 18.6681971719 398.421086601 324.778913399
BXD40 m 123.0 20.8716789468 164.1672263226 81.8327736774
BXD43 m 154.0 24.1005389168 201.5358183983 106.4641816017
BXD44 m 390.8888888889 13.9144526312 418.3337064373 363.4440713405
BXD45 m 171.25 20.8716789468 212.4172263226 130.0827736774
BXD48 m 175.25 20.8716789468 216.4172263226 134.0827736774
BXD48a m 240.6666666667 24.1005389168 288.202485065 193.1308482684
BXD49 m 165.5 20.8716789468 206.6672263226 124.3327736774
BXD50 m 156.6 18.6681971719 193.421086601 119.778913399
BXD51 m 155.25 20.8716789468 196.4172263226 114.0827736774
BXD53 m 197.2 18.6681971719 234.021086601 160.378913399
BXD55 m 131.25 20.8716789468 172.4172263226 90.0827736774
BXD56 m 188.25 20.8716789468 229.4172263226 147.0827736774
BXD6 m 130.6 18.6681971719 167.421086601 93.778913399
BXD60 m 198.8 18.6681971719 235.621086601 161.978913399
BXD61 m 160.6 18.6681971719 197.421086601 123.778913399
BXD62 m 178.0 20.8716789468 219.1672263226 136.8327736774
BXD63 m 281.25 20.8716789468 322.4172263226 240.0827736774
BXD64 m 340.25 20.8716789468 381.4172263226 299.0827736774
BXD65 m 208.25 20.8716789468 249.4172263226 167.0827736774
BXD65a m 178.0 20.8716789468 219.1672263226 136.8327736774
BXD66 m 136.25 20.8716789468 177.4172263226 95.0827736774
BXD67 m 178.8 18.6681971719 215.621086601 141.978913399
BXD68 m 125.5 20.8716789468 166.6672263226 84.3327736774
BXD69 m 278.2 18.6681971719 315.021086601 241.378913399
BXD70 m 141.5 20.8716789468 182.6672263226 100.3327736774
BXD71 m 357.6666666667 24.1005389168 405.202485065 310.1308482684
BXD73 m 152.0 18.6681971719 188.821086601 115.178913399
BXD73a m 173.0 20.8716789468 214.1672263226 131.8327736774
BXD73b m 197.2 18.6681971719 234.021086601 160.378913399
BXD75 m 150.6 18.6681971719 187.421086601 113.778913399
BXD77 m 205.2 18.6681971719 242.021086601 168.378913399
BXD79 m 292.8 18.6681971719 329.621086601 255.978913399
BXD8 m 140.0 18.6681971719 176.821086601 103.178913399
BXD81 m 250.0 20.8716789468 291.1672263226 208.8327736774
BXD83 m 191.25 20.8716789468 232.4172263226 150.0827736774
BXD84 m 334.3333333333 24.1005389168 381.8691517316 286.797514935
BXD85 m 329.25 20.8716789468 370.4172263226 288.0827736774
BXD87 m 157.6 18.6681971719 194.421086601 120.778913399
BXD89 m 123.25 20.8716789468 164.4172263226 82.0827736774
BXD90 m 151.25 20.8716789468 192.4172263226 110.0827736774
BXD95 m 204.8 18.6681971719 241.621086601 167.978913399
BXD98 m 407.4 18.6681971719 444.221086601 370.578913399
BXD99 m 230.2 18.6681971719 267.021086601 193.378913399
C57BL/6J m 196.5 20.8716789468 237.6672263226 155.3327736774
DBA/2J m 180.3333333333 24.1005389168 227.8691517316 132.797514935




  GWAS USING LINEAR MIXED MODELS