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Project measure / variable:   Auwerx1   ogtt_gluc_t180_CD

ID, description, units MPD:111260   ogtt_gluc_t180_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 180 min   [mg/dL]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 180 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means133.9   mg/dL
Median of the strain means125.2   mg/dL
SD of the strain means± 38.729
Coefficient of variation (CV)0.2891
Min–max range of strain means79.25   –   293.6   mg/dL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 434900.1611 7766.0743 9.3937 < 0.0001
Residuals 199 164519.8389 826.7329


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 99.6 11.194   5 5.006 0.1124 87.0, 117.0 -0.89
BXD100 m 144.3 21.079   3 12.17 0.146 121.0, 162.0 0.27
BXD101 m 116.5 8.0623   4 4.0311 0.0692 107.0, 125.0 -0.45
BXD11 m 111.5 33.272   4 16.636 0.2984 77.0, 157.0 -0.58
BXD12 m 102.4 6.1887   5 2.7677 0.0604 94.0, 111.0 -0.81
BXD16 m 143.2 21.593   4 10.796 0.1507 114.0, 166.0 0.24
BXD2 m 120.2 9.215   4 4.6075 0.0766 110.0, 129.0 -0.35
BXD27 m 131.0 18.561   5 8.3006 0.1417 106.0, 153.0 -0.08
BXD32 m 92.2 14.132   5 6.3198 0.1533 77.0, 114.0 -1.08
BXD34 m 130.2 25.773   4 12.887 0.1979 99.0, 162.0 -0.1
BXD39 m 200.4 24.886   5 11.129 0.1242 170.0, 228.0 1.72
BXD40 m 109.8 14.315   4 7.1575 0.1304 97.0, 129.0 -0.62
BXD43 m 125.2 13.15   4 6.5749 0.105 111.0, 140.0 -0.23
BXD44 m 235.8 45.653   9 15.218 0.1936 160.0, 305.0 2.63
BXD45 m 154.8 21.297   4 10.649 0.1376 135.0, 182.0 0.54
BXD48 m 113.2 20.871   4 10.435 0.1843 92.0, 137.0 -0.54
BXD48a m 147.6 16.041   5 7.1736 0.1087 126.0, 162.0 0.35
BXD49 m 126.8 9.3229   4 4.6615 0.0736 117.0, 139.0 -0.18
BXD50 m 137.5 27.635   4 13.817 0.201 100.0, 162.0 0.09
BXD51 m 117.0 25.338   4 12.669 0.2166 96.0, 147.0 -0.44
BXD53 m 98.6 15.978   5 7.1456 0.162 79.0, 121.0 -0.91
BXD55 m 125.8 24.813   5 11.097 0.1972 104.0, 167.0 -0.21
BXD56 m 127.8 15.834   5 7.081 0.1239 105.0, 143.0 -0.16
BXD6 m 108.6 12.934   5 5.7845 0.1191 93.0, 128.0 -0.65
BXD60 m 110.2 23.637   5 10.571 0.2145 71.0, 135.0 -0.61
BXD61 m 103.0 7.2111   3 4.1633 0.07 95.0, 109.0 -0.8
BXD62 m 121.2 15.478   4 7.7392 0.1277 108.0, 142.0 -0.33
BXD63 m 168.2 13.846   5 6.1919 0.0823 144.0, 179.0 0.88
BXD64 m 168.0 109.7   4 54.83 0.6528 95.0, 330.0 0.88
BXD65 m 169.8 11.529   4 5.7645 0.0679 157.0, 183.0 0.93
BXD65a m 189.4 59.23   5 26.489 0.3127 144.0, 289.0 1.43
BXD65b m 188.8 29.703   4 14.851 0.1574 160.0, 220.0 1.42
BXD66 m 111.2 13.5   4 6.75 0.1213 94.0, 127.0 -0.59
BXD67 m 118.0 14.3   5 6.3953 0.1212 104.0, 139.0 -0.41
BXD68 m 126.0 26.239   5 11.735 0.2082 99.0, 158.0 -0.21
BXD69 m 293.6 87.73   5 39.233 0.2988 196.0, 410.0 4.12
BXD70 m 90.25 20.759   4 10.379 0.23 61.0, 110.0 -1.13
BXD71 m 122.2 10.71   5 4.7896 0.0876 110.0, 135.0 -0.3
BXD73 m 176.2 23.796   4 11.898 0.135 153.0, 209.0 1.09
BXD73a m 133.5 15.524   4 7.7621 0.1163 113.0, 149.0 -0.01
BXD73b m 169.6 20.888   5 9.3413 0.1232 149.0, 201.0 0.92
BXD75 m 105.0 12.629   5 5.648 0.1203 89.0, 121.0 -0.75
BXD77 m 126.0 12.845   5 5.7446 0.1019 111.0, 142.0 -0.21
BXD79 m 146.0 14.44   5 6.4576 0.0989 128.0, 162.0 0.31
BXD8 m 95.0 22.166   4 11.083 0.2333 67.0, 120.0 -1.01
BXD81 m 100.8 14.245   4 7.1224 0.1414 83.0, 115.0 -0.86
BXD83 m 117.3 9.4516   3 5.4569 0.0806 110.0, 128.0 -0.43
BXD84 m 160.4 9.9146   5 4.434 0.0618 146.0, 168.0 0.68
BXD85 m 203.4 52.96   5 23.682 0.2604 156.0, 265.0 1.79
BXD87 m 108.4 10.262   5 4.5891 0.0947 100.0, 126.0 -0.66
BXD89 m 79.25 16.82   4 8.4101 0.2122 67.0, 104.0 -1.41
BXD90 m 96.0 14.353   4 7.1764 0.1495 76.0, 109.0 -0.98
BXD95 m 137.8 22.736   4 11.368 0.1651 113.0, 168.0 0.1
BXD98 m 155.0 12.923   5 5.7793 0.0834 138.0, 170.0 0.54
BXD99 m 118.0 12.55   5 5.6125 0.1064 102.0, 133.0 -0.41
C57BL/6J m 111.5 13.178   4 6.5891 0.1182 92.0, 120.0 -0.58
DBA/2J m 96.0 17.87   4 8.935 0.1861 74.0, 116.0 -0.98


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 99.6 12.8587157892 124.9568287512 74.2431712488
BXD100 m 144.3333333333 16.6005307017 177.0688584887 111.597808178
BXD101 m 116.5 14.376481304 144.8497963908 88.1502036092
BXD11 m 111.5 14.376481304 139.8497963908 83.1502036092
BXD12 m 102.4 12.8587157892 127.7568287512 77.0431712488
BXD16 m 143.25 14.376481304 171.5997963908 114.9002036092
BXD2 m 120.25 14.376481304 148.5997963908 91.9002036092
BXD27 m 131.0 12.8587157892 156.3568287512 105.6431712488
BXD32 m 92.2 12.8587157892 117.5568287512 66.8431712488
BXD34 m 130.25 14.376481304 158.5997963908 101.9002036092
BXD39 m 200.4 12.8587157892 225.7568287512 175.0431712488
BXD40 m 109.75 14.376481304 138.0997963908 81.4002036092
BXD43 m 125.25 14.376481304 153.5997963908 96.9002036092
BXD44 m 235.7777777778 9.5843208693 254.6776420383 216.8779135173
BXD45 m 154.75 14.376481304 183.0997963908 126.4002036092
BXD48 m 113.25 14.376481304 141.5997963908 84.9002036092
BXD48a m 147.6 12.8587157892 172.9568287512 122.2431712488
BXD49 m 126.75 14.376481304 155.0997963908 98.4002036092
BXD50 m 137.5 14.376481304 165.8497963908 109.1502036092
BXD51 m 117.0 14.376481304 145.3497963908 88.6502036092
BXD53 m 98.6 12.8587157892 123.9568287512 73.2431712488
BXD55 m 125.8 12.8587157892 151.1568287512 100.4431712488
BXD56 m 127.8 12.8587157892 153.1568287512 102.4431712488
BXD6 m 108.6 12.8587157892 133.9568287512 83.2431712488
BXD60 m 110.2 12.8587157892 135.5568287512 84.8431712488
BXD61 m 103.0 16.6005307017 135.7355251553 70.2644748447
BXD62 m 121.25 14.376481304 149.5997963908 92.9002036092
BXD63 m 168.2 12.8587157892 193.5568287512 142.8431712488
BXD64 m 168.0 14.376481304 196.3497963908 139.6502036092
BXD65 m 169.75 14.376481304 198.0997963908 141.4002036092
BXD65a m 189.4 12.8587157892 214.7568287512 164.0431712488
BXD65b m 188.75 14.376481304 217.0997963908 160.4002036092
BXD66 m 111.25 14.376481304 139.5997963908 82.9002036092
BXD67 m 118.0 12.8587157892 143.3568287512 92.6431712488
BXD68 m 126.0 12.8587157892 151.3568287512 100.6431712488
BXD69 m 293.6 12.8587157892 318.9568287512 268.2431712488
BXD70 m 90.25 14.376481304 118.5997963908 61.9002036092
BXD71 m 122.2 12.8587157892 147.5568287512 96.8431712488
BXD73 m 176.25 14.376481304 204.5997963908 147.9002036092
BXD73a m 133.5 14.376481304 161.8497963908 105.1502036092
BXD73b m 169.6 12.8587157892 194.9568287512 144.2431712488
BXD75 m 105.0 12.8587157892 130.3568287512 79.6431712488
BXD77 m 126.0 12.8587157892 151.3568287512 100.6431712488
BXD79 m 146.0 12.8587157892 171.3568287512 120.6431712488
BXD8 m 95.0 14.376481304 123.3497963908 66.6502036092
BXD81 m 100.75 14.376481304 129.0997963908 72.4002036092
BXD83 m 117.3333333333 16.6005307017 150.0688584887 84.597808178
BXD84 m 160.4 12.8587157892 185.7568287512 135.0431712488
BXD85 m 203.4 12.8587157892 228.7568287512 178.0431712488
BXD87 m 108.4 12.8587157892 133.7568287512 83.0431712488
BXD89 m 79.25 14.376481304 107.5997963908 50.9002036092
BXD90 m 96.0 14.376481304 124.3497963908 67.6502036092
BXD95 m 137.75 14.376481304 166.0997963908 109.4002036092
BXD98 m 155.0 12.8587157892 180.3568287512 129.6431712488
BXD99 m 118.0 12.8587157892 143.3568287512 92.6431712488
C57BL/6J m 111.5 14.376481304 139.8497963908 83.1502036092
DBA/2J m 96.0 14.376481304 124.3497963908 67.6502036092




  GWAS USING LINEAR MIXED MODELS