Project measure / variable:   Auwerx1   ogtt_gluc_t120_HFD

ID, description, units MPD:111257   ogtt_gluc_t120_HFD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 120 min   [mg/dL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 120 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means269.6   mg/dL
Median of the strain means234.1   mg/dL
SD of the strain means± 107.5
Coefficient of variation (CV)0.3986
Min–max range of strain means143.0   –   542.6   mg/dL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 3066793.6126 55759.8839 15.9657 < 0.0001
Residuals 192 670554.3833 3492.4707


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 180.0 64.98   5 29.06 0.361 101.0, 267.0 -0.83
BXD100 m 233.4 71.74   5 32.085 0.3074 157.0, 350.0 -0.34
BXD101 m 170.2 5.6199   4 2.81 0.033 163.0, 176.0 -0.92
BXD11 m 192.0 35.468   5 15.862 0.1847 162.0, 251.0 -0.72
BXD12 m 149.0 31.646   5 14.153 0.2124 132.0, 205.0 -1.12
BXD16 m 252.4 54.52   5 24.382 0.216 210.0, 328.0 -0.16
BXD2 m 166.6 35.837   5 16.027 0.2151 109.0, 199.0 -0.96
BXD27 m 379.5 81.32   4 40.662 0.2143 276.0, 472.0 1.02
BXD32 m 235.3 129.6   3 74.83 0.5508 160.0, 385.0 -0.32
BXD34 m 167.8 33.162   5 14.83 0.1976 123.0, 202.0 -0.95
BXD39 m 492.4 60.33   5 26.981 0.1225 403.0, 557.0 2.07
BXD40 m 167.0 27.215   4 13.608 0.163 142.0, 197.0 -0.95
BXD43 m 262.3 42.099   3 24.306 0.1605 214.0, 291.0 -0.07
BXD44 m 530.0 66.04   9 22.013 0.1246 415.0, 600.0 2.42
BXD45 m 219.5 22.249   4 11.124 0.1014 200.0, 251.0 -0.47
BXD48 m 270.8 59.86   4 29.932 0.2211 193.0, 338.0 0.01
BXD48a m 341.7 115.4   3 66.62 0.3377 213.0, 436.0 0.67
BXD49 m 187.0 40.604   4 20.302 0.2171 142.0, 236.0 -0.77
BXD50 m 193.4 13.667   5 6.1123 0.0707 182.0, 213.0 -0.71
BXD51 m 193.5 41.637   4 20.819 0.2152 147.0, 242.0 -0.71
BXD53 m 254.6 88.5   5 39.579 0.3476 177.0, 400.0 -0.14
BXD55 m 144.2 8.7321   4 4.3661 0.0605 135.0, 156.0 -1.17
BXD56 m 271.8 58.73   4 29.364 0.2161 211.0, 339.0 0.02
BXD6 m 178.2 18.499   5 8.2728 0.1038 147.0, 192.0 -0.85
BXD60 m 243.8 23.059   5 10.312 0.0946 225.0, 275.0 -0.24
BXD61 m 207.0 44.822   5 20.045 0.2165 151.0, 258.0 -0.58
BXD62 m 253.0 113.2   4 56.6 0.4474 156.0, 414.0 -0.15
BXD63 m 443.8 41.812   4 20.906 0.0942 388.0, 488.0 1.62
BXD64 m 436.5 65.78   4 32.89 0.1507 375.0, 520.0 1.55
BXD65 m 292.8 70.83   4 35.415 0.2419 204.0, 374.0 0.22
BXD65a m 289.8 80.18   4 40.09 0.2767 211.0, 368.0 0.19
BXD66 m 153.0 14.306   4 7.1531 0.0935 142.0, 174.0 -1.08
BXD67 m 292.4 40.209   5 17.982 0.1375 264.0, 361.0 0.21
BXD68 m 231.0 72.37   4 36.187 0.3133 141.0, 309.0 -0.36
BXD69 m 489.2 14.636   5 6.5452 0.0299 466.0, 505.0 2.04
BXD70 m 170.8 54.4   4 27.201 0.3186 121.0, 234.0 -0.92
BXD71 m 440.0 74.0   3 42.724 0.1682 360.0, 506.0 1.59
BXD73 m 215.6 39.259   5 17.557 0.1821 171.0, 260.0 -0.5
BXD73a m 198.2 13.2   4 6.6002 0.0666 181.0, 213.0 -0.66
BXD73b m 225.2 51.26   5 22.925 0.2276 166.0, 296.0 -0.41
BXD75 m 234.8 77.82   5 34.804 0.3315 163.0, 352.0 -0.32
BXD77 m 285.2 64.92   5 29.032 0.2276 177.0, 337.0 0.15
BXD79 m 348.4 113.6   5 50.81 0.3261 181.0, 487.0 0.73
BXD8 m 169.4 33.419   5 14.945 0.1973 132.0, 204.0 -0.93
BXD81 m 375.8 30.988   4 15.494 0.0825 331.0, 402.0 0.99
BXD83 m 230.5 55.63   4 27.813 0.2413 191.0, 309.0 -0.36
BXD84 m 472.3 77.68   3 44.849 0.1645 383.0, 524.0 1.89
BXD85 m 423.5 105.0   4 52.51 0.248 306.0, 539.0 1.43
BXD87 m 227.6 88.32   5 39.498 0.388 162.0, 378.0 -0.39
BXD89 m 143.0 43.612   4 21.806 0.305 78.0, 171.0 -1.18
BXD90 m 184.0 7.3937   4 3.6968 0.0402 179.0, 195.0 -0.8
BXD95 m 286.2 68.39   5 30.587 0.239 221.0, 400.0 0.15
BXD98 m 542.6 40.022   5 17.899 0.0738 484.0, 586.0 2.54
BXD99 m 331.0 68.54   5 30.653 0.2071 228.0, 412.0 0.57
C57BL/6J m 229.8 21.624   4 10.812 0.0941 206.0, 255.0 -0.37
DBA/2J m 197.3 32.316   3 18.658 0.1638 173.0, 234.0 -0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 180.0 26.4290398862 232.1285455404 127.8714544596
BXD100 m 233.4 26.4290398862 285.5285455404 181.2714544597
BXD101 m 170.25 29.5485648828 228.5314856982 111.9685143018
BXD11 m 192.0 26.4290398862 244.1285455404 139.8714544596
BXD12 m 149.0 26.4290398862 201.1285455404 96.8714544596
BXD16 m 252.4 26.4290398862 304.5285455404 200.2714544596
BXD2 m 166.6 26.4290398862 218.7285455404 114.4714544596
BXD27 m 379.5 29.5485648828 437.7814856982 321.2185143018
BXD32 m 235.3333333333 34.1197437785 302.6309962466 168.0356704201
BXD34 m 167.8 26.4290398862 219.9285455404 115.6714544596
BXD39 m 492.4 26.4290398862 544.5285455403 440.2714544596
BXD40 m 167.0 29.5485648828 225.2814856982 108.7185143018
BXD43 m 262.3333333333 34.1197437785 329.6309962466 195.0356704201
BXD44 m 530.0 19.6990432552 568.8543237988 491.1456762012
BXD45 m 219.5 29.5485648828 277.7814856982 161.2185143018
BXD48 m 270.75 29.5485648828 329.0314856982 212.4685143018
BXD48a m 341.6666666667 34.1197437785 408.9643295799 274.3690037534
BXD49 m 187.0 29.5485648828 245.2814856982 128.7185143018
BXD50 m 193.4 26.4290398862 245.5285455404 141.2714544596
BXD51 m 193.5 29.5485648828 251.7814856982 135.2185143018
BXD53 m 254.6 26.4290398862 306.7285455404 202.4714544596
BXD55 m 144.25 29.5485648828 202.5314856982 85.9685143018
BXD56 m 271.75 29.5485648828 330.0314856982 213.4685143018
BXD6 m 178.2 26.4290398862 230.3285455404 126.0714544596
BXD60 m 243.8 26.4290398862 295.9285455404 191.6714544596
BXD61 m 207.0 26.4290398862 259.1285455404 154.8714544596
BXD62 m 253.0 29.5485648828 311.2814856982 194.7185143018
BXD63 m 443.75 29.5485648828 502.0314856982 385.4685143018
BXD64 m 436.5 29.5485648828 494.7814856982 378.2185143018
BXD65 m 292.75 29.5485648828 351.0314856982 234.4685143018
BXD65a m 289.75 29.5485648828 348.0314856982 231.4685143018
BXD66 m 153.0 29.5485648828 211.2814856982 94.7185143018
BXD67 m 292.4 26.4290398862 344.5285455404 240.2714544596
BXD68 m 231.0 29.5485648828 289.2814856982 172.7185143018
BXD69 m 489.2 26.4290398862 541.3285455404 437.0714544596
BXD70 m 170.75 29.5485648828 229.0314856982 112.4685143018
BXD71 m 440.0 34.1197437785 507.2976629133 372.7023370867
BXD73 m 215.6 26.4290398862 267.7285455404 163.4714544596
BXD73a m 198.25 29.5485648828 256.5314856982 139.9685143018
BXD73b m 225.2 26.4290398862 277.3285455404 173.0714544596
BXD75 m 234.8 26.4290398862 286.9285455404 182.6714544596
BXD77 m 285.2 26.4290398862 337.3285455404 233.0714544596
BXD79 m 348.4 26.4290398862 400.5285455404 296.2714544596
BXD8 m 169.4 26.4290398862 221.5285455404 117.2714544596
BXD81 m 375.75 29.5485648828 434.0314856982 317.4685143018
BXD83 m 230.5 29.5485648828 288.7814856982 172.2185143018
BXD84 m 472.3333333333 34.1197437785 539.6309962466 405.0356704201
BXD85 m 423.5 29.5485648828 481.7814856982 365.2185143018
BXD87 m 227.6 26.4290398862 279.7285455404 175.4714544596
BXD89 m 143.0 29.5485648828 201.2814856982 84.7185143018
BXD90 m 184.0 29.5485648828 242.2814856982 125.7185143018
BXD95 m 286.2 26.4290398862 338.3285455404 234.0714544596
BXD98 m 542.6 26.4290398862 594.7285455404 490.4714544596
BXD99 m 331.0 26.4290398862 383.1285455404 278.8714544596
C57BL/6J m 229.75 29.5485648828 288.0314856982 171.4685143018
DBA/2J m 197.3333333333 34.1197437785 264.6309962466 130.0356704201




  GWAS USING LINEAR MIXED MODELS