Project measure / variable:   Auwerx1   ogtt_gluc_t120_CD

ID, description, units MPD:111256   ogtt_gluc_t120_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 120 min   [mg/dL]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 120 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means168.1   mg/dL
Median of the strain means147.8   mg/dL
SD of the strain means± 61.16
Coefficient of variation (CV)0.3639
Min–max range of strain means94.5   –   425.0   mg/dL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 1179644.4594 21065.0796 13.1915 < 0.0001
Residuals 199 317776.9 1596.8688


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 114.0 6.4031   5 2.8636 0.0562 103.0, 119.0 -0.88
BXD100 m 219.3 12.097   3 6.9841 0.0552 210.0, 233.0 0.84
BXD101 m 167.0 12.083   4 6.0415 0.0724 160.0, 185.0 -0.02
BXD11 m 147.8 55.27   4 27.633 0.374 95.0, 225.0 -0.33
BXD12 m 122.6 7.1624   5 3.2031 0.0584 117.0, 134.0 -0.74
BXD16 m 212.8 59.16   4 29.581 0.2781 133.0, 275.0 0.73
BXD2 m 140.0 4.8305   4 2.4152 0.0345 133.0, 144.0 -0.46
BXD27 m 195.2 45.991   5 20.568 0.2356 159.0, 266.0 0.44
BXD32 m 115.4 18.69   5 8.3582 0.162 92.0, 138.0 -0.86
BXD34 m 179.2 32.786   4 16.393 0.1829 140.0, 211.0 0.18
BXD39 m 248.6 25.255   5 11.294 0.1016 218.0, 272.0 1.32
BXD40 m 120.0 6.4807   4 3.2404 0.054 113.0, 128.0 -0.79
BXD43 m 180.0 22.978   4 11.489 0.1277 150.0, 206.0 0.2
BXD44 m 385.0 90.01   9 30.002 0.2338 248.0, 536.0 3.55
BXD45 m 155.2 10.308   4 5.1539 0.0664 140.0, 162.0 -0.21
BXD48 m 145.2 14.997   4 7.4986 0.1033 129.0, 158.0 -0.37
BXD48a m 182.0 25.564   5 11.432 0.1405 152.0, 217.0 0.23
BXD49 m 143.8 12.738   4 6.3689 0.0886 125.0, 153.0 -0.4
BXD50 m 179.2 35.753   4 17.876 0.1995 142.0, 223.0 0.18
BXD51 m 142.5 21.205   4 10.603 0.1488 113.0, 163.0 -0.42
BXD53 m 112.6 14.741   5 6.5924 0.1309 87.0, 124.0 -0.91
BXD55 m 118.4 16.577   5 7.4135 0.14 105.0, 141.0 -0.81
BXD56 m 176.2 44.314   5 19.818 0.2515 133.0, 237.0 0.13
BXD6 m 135.2 14.325   5 6.4062 0.106 119.0, 153.0 -0.54
BXD60 m 136.2 32.019   5 14.319 0.2351 89.0, 175.0 -0.52
BXD61 m 135.7 10.97   3 6.3333 0.0809 127.0, 148.0 -0.53
BXD62 m 133.5 23.302   4 11.651 0.1745 118.0, 168.0 -0.56
BXD63 m 221.4 37.554   5 16.795 0.1696 181.0, 279.0 0.87
BXD64 m 195.0 106.5   4 53.23 0.546 120.0, 350.0 0.44
BXD65 m 209.2 33.984   4 16.992 0.1624 183.0, 259.0 0.67
BXD65a m 262.8 125.8   5 56.24 0.4785 176.0, 484.0 1.55
BXD65b m 205.5 29.034   4 14.517 0.1413 164.0, 227.0 0.61
BXD66 m 127.2 12.685   4 6.3426 0.0997 112.0, 143.0 -0.67
BXD67 m 129.2 15.991   5 7.1512 0.1238 117.0, 150.0 -0.64
BXD68 m 163.2 40.592   5 18.153 0.2487 116.0, 213.0 -0.08
BXD69 m 425.0 73.47   5 32.856 0.1729 343.0, 514.0 4.2
BXD70 m 94.5 20.372   4 10.186 0.2156 64.0, 106.0 -1.2
BXD71 m 174.4 17.242   5 7.711 0.0989 154.0, 192.0 0.1
BXD73 m 170.8 9.8107   4 4.9054 0.0575 158.0, 181.0 0.04
BXD73a m 154.8 13.72   4 6.8602 0.0887 139.0, 172.0 -0.22
BXD73b m 200.0 27.139   5 12.137 0.1357 166.0, 238.0 0.52
BXD75 m 133.8 20.849   5 9.3242 0.1558 114.0, 169.0 -0.56
BXD77 m 145.8 24.181   5 10.814 0.1658 133.0, 189.0 -0.36
BXD79 m 181.4 19.807   5 8.8578 0.1092 150.0, 201.0 0.22
BXD8 m 109.0 27.773   4 13.886 0.2548 68.0, 129.0 -0.97
BXD81 m 117.8 13.022   4 6.5112 0.1106 106.0, 130.0 -0.82
BXD83 m 141.7 11.504   3 6.6416 0.0812 130.0, 153.0 -0.43
BXD84 m 199.6 32.746   5 14.644 0.1641 150.0, 238.0 0.52
BXD85 m 262.4 64.84   5 28.998 0.2471 183.0, 350.0 1.54
BXD87 m 134.6 16.196   5 7.2429 0.1203 117.0, 160.0 -0.55
BXD89 m 102.5 16.823   4 8.4113 0.1641 87.0, 126.0 -1.07
BXD90 m 104.2 17.951   4 8.9757 0.1722 85.0, 121.0 -1.04
BXD95 m 173.5 16.135   4 8.0674 0.093 156.0, 194.0 0.09
BXD98 m 207.6 40.079   5 17.924 0.1931 166.0, 273.0 0.65
BXD99 m 147.8 25.646   5 11.469 0.1735 118.0, 175.0 -0.33
C57BL/6J m 142.0 11.972   4 5.9861 0.0843 126.0, 155.0 -0.43
DBA/2J m 99.75 19.225   4 9.6123 0.1927 74.0, 118.0 -1.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 114.0 17.8710315551 149.2408976277 78.7591023723
BXD100 m 219.3333333333 23.0714025308 264.8291365391 173.8375301276
BXD101 m 167.0 19.9804206926 206.4005213418 127.5994786582
BXD11 m 147.75 19.9804206927 187.1505213418 108.3494786582
BXD12 m 122.6 17.8710315551 157.8408976277 87.3591023723
BXD16 m 212.75 19.9804206926 252.1505213418 173.3494786582
BXD2 m 140.0 19.9804206927 179.4005213418 100.5994786582
BXD27 m 195.2 17.8710315551 230.4408976277 159.9591023723
BXD32 m 115.4 17.8710315551 150.6408976277 80.1591023723
BXD34 m 179.25 19.9804206926 218.6505213418 139.8494786582
BXD39 m 248.6 17.8710315551 283.8408976277 213.3591023723
BXD40 m 120.0 19.9804206927 159.4005213418 80.5994786582
BXD43 m 180.0 19.9804206927 219.4005213418 140.5994786582
BXD44 m 385.0 13.3202804618 411.2670142279 358.7329857722
BXD45 m 155.25 19.9804206926 194.6505213418 115.8494786582
BXD48 m 145.25 19.9804206926 184.6505213418 105.8494786582
BXD48a m 182.0 17.8710315551 217.2408976277 146.7591023723
BXD49 m 143.75 19.9804206926 183.1505213418 104.3494786582
BXD50 m 179.25 19.9804206927 218.6505213418 139.8494786582
BXD51 m 142.5 19.9804206926 181.9005213418 103.0994786582
BXD53 m 112.6 17.8710315551 147.8408976277 77.3591023723
BXD55 m 118.4 17.8710315551 153.6408976277 83.1591023723
BXD56 m 176.2 17.8710315551 211.4408976277 140.9591023723
BXD6 m 135.2 17.8710315551 170.4408976277 99.9591023723
BXD60 m 136.2 17.8710315551 171.4408976277 100.9591023723
BXD61 m 135.6666666667 23.0714025308 181.1624698724 90.1708634609
BXD62 m 133.5 19.9804206927 172.9005213418 94.0994786582
BXD63 m 221.4 17.8710315551 256.6408976277 186.1591023723
BXD64 m 195.0 19.9804206926 234.4005213418 155.5994786582
BXD65 m 209.25 19.9804206926 248.6505213418 169.8494786582
BXD65a m 262.8 17.8710315551 298.0408976277 227.5591023723
BXD65b m 205.5 19.9804206926 244.9005213418 166.0994786582
BXD66 m 127.25 19.9804206927 166.6505213418 87.8494786582
BXD67 m 129.2 17.8710315551 164.4408976277 93.9591023723
BXD68 m 163.2 17.8710315551 198.4408976277 127.9591023723
BXD69 m 425.0 17.8710315551 460.2408976277 389.7591023723
BXD70 m 94.5 19.9804206926 133.9005213418 55.0994786582
BXD71 m 174.4 17.8710315551 209.6408976277 139.1591023723
BXD73 m 170.75 19.9804206926 210.1505213418 131.3494786582
BXD73a m 154.75 19.9804206926 194.1505213418 115.3494786582
BXD73b m 200.0 17.8710315551 235.2408976277 164.7591023723
BXD75 m 133.8 17.8710315551 169.0408976277 98.5591023723
BXD77 m 145.8 17.8710315551 181.0408976277 110.5591023723
BXD79 m 181.4 17.8710315551 216.6408976277 146.1591023723
BXD8 m 109.0 19.9804206926 148.4005213418 69.5994786582
BXD81 m 117.75 19.9804206927 157.1505213418 78.3494786582
BXD83 m 141.6666666667 23.0714025308 187.1624698724 96.1708634609
BXD84 m 199.6 17.8710315551 234.8408976277 164.3591023723
BXD85 m 262.4 17.8710315551 297.6408976277 227.1591023723
BXD87 m 134.6 17.8710315551 169.8408976277 99.3591023723
BXD89 m 102.5 19.9804206926 141.9005213418 63.0994786582
BXD90 m 104.25 19.9804206926 143.6505213418 64.8494786582
BXD95 m 173.5 19.9804206927 212.9005213418 134.0994786582
BXD98 m 207.6 17.8710315551 242.8408976277 172.3591023723
BXD99 m 147.8 17.8710315551 183.0408976277 112.5591023723
C57BL/6J m 142.0 19.9804206927 181.4005213418 102.5994786582
DBA/2J m 99.75 19.9804206927 139.1505213418 60.3494786582




  GWAS USING LINEAR MIXED MODELS