Project measure / variable:   Auwerx1   ogtt_gluc_t90_HFD

ID, description, units MPD:111255   ogtt_gluc_t90_HFD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 90 min   [mg/dL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   54 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 90 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested54 strains
Mean of the strain means326.0   mg/dL
Median of the strain means312.4   mg/dL
SD of the strain means± 117.8
Coefficient of variation (CV)0.3614
Min–max range of strain means149.0   –   584.8   mg/dL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 53 3150160.3702 59436.9881 12.558 < 0.0001
Residuals 181 856673.8 4733.0044


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 262.6 68.54   5 30.652 0.261 181.0, 360.0 -0.54
BXD100 m 292.6 79.57   5 35.583 0.2719 213.0, 418.0 -0.28
BXD101 m 196.0 6.9761   4 3.4881 0.0356 190.0, 203.0 -1.1
BXD11 m 253.0 76.7   5 34.303 0.3032 164.0, 328.0 -0.62
BXD12 m 190.6 40.796   5 18.244 0.214 156.0, 256.0 -1.15
BXD16 m 388.2 93.7   5 41.905 0.2414 274.0, 478.0 0.53
BXD2 m 187.6 43.85   5 19.61 0.2337 127.0, 224.0 -1.17
BXD27 m 489.8 66.53   4 33.265 0.1358 415.0, 577.0 1.39
BXD32 m 308.0 166.7   3 96.23 0.5412 192.0, 499.0 -0.15
BXD34 m 214.8 34.018   5 15.213 0.1584 160.0, 251.0 -0.94
BXD39 m 534.8 60.09   5 26.873 0.1124 467.0, 600.0 1.77
BXD40 m 239.8 35.566   4 17.783 0.1483 207.0, 272.0 -0.73
BXD43 m 353.7 14.572   3 8.413 0.0412 342.0, 370.0 0.24
BXD44 m 573.8 31.732   4 15.866 0.0553 536.0, 600.0 2.1
BXD48 m 371.2 73.82   4 36.908 0.1988 303.0, 476.0 0.38
BXD48a m 390.7 155.0   3 89.5 0.3968 214.0, 504.0 0.55
BXD49 m 195.5 30.216   4 15.108 0.1546 166.0, 232.0 -1.11
BXD50 m 223.2 23.637   5 10.571 0.1059 188.0, 244.0 -0.87
BXD53 m 317.0 105.1   5 47.02 0.3317 221.0, 489.0 -0.08
BXD55 m 173.8 5.1881   4 2.5941 0.0299 169.0, 180.0 -1.29
BXD56 m 324.5 53.71   4 26.853 0.1655 277.0, 372.0 -0.01
BXD6 m 235.8 29.389   5 13.143 0.1246 189.0, 261.0 -0.77
BXD60 m 312.4 31.667   5 14.162 0.1014 260.0, 340.0 -0.12
BXD61 m 243.4 79.77   5 35.673 0.3277 165.0, 371.0 -0.7
BXD62 m 312.5 108.8   4 54.38 0.348 192.0, 454.0 -0.11
BXD63 m 529.0 53.89   4 26.947 0.1019 450.0, 569.0 1.72
BXD64 m 475.5 102.7   4 51.33 0.2159 354.0, 600.0 1.27
BXD65 m 325.5 97.69   4 48.844 0.3001 223.0, 412.0 0.0
BXD65a m 383.5 48.46   4 24.23 0.1264 329.0, 447.0 0.49
BXD66 m 178.2 17.366   4 8.6831 0.0974 166.0, 204.0 -1.25
BXD67 m 381.8 55.0   5 24.596 0.144 335.0, 475.0 0.47
BXD68 m 315.0 91.59   4 45.795 0.2908 188.0, 397.0 -0.09
BXD69 m 577.0 33.121   5 14.812 0.0574 528.0, 600.0 2.13
BXD70 m 248.5 113.9   4 56.94 0.4583 158.0, 407.0 -0.66
BXD71 m 504.0 91.66   3 52.92 0.1819 400.0, 573.0 1.51
BXD73 m 255.4 30.072   5 13.448 0.1177 219.0, 287.0 -0.6
BXD73a m 244.2 36.372   4 18.186 0.1489 212.0, 281.0 -0.69
BXD73b m 235.8 53.2   5 23.794 0.2256 189.0, 312.0 -0.77
BXD75 m 316.6 90.21   5 40.344 0.2849 214.0, 430.0 -0.08
BXD77 m 374.6 81.01   5 36.231 0.2163 239.0, 449.0 0.41
BXD79 m 366.2 113.5   5 50.78 0.31 218.0, 482.0 0.34
BXD8 m 210.0 61.55   5 27.526 0.2931 140.0, 284.0 -0.98
BXD81 m 430.0 54.63   4 27.316 0.1271 358.0, 479.0 0.88
BXD83 m 257.2 66.89   4 33.447 0.26 201.0, 353.0 -0.58
BXD84 m 531.7 72.86   3 42.065 0.137 455.0, 600.0 1.75
BXD85 m 440.0 78.91   4 39.455 0.1793 354.0, 508.0 0.97
BXD87 m 277.6 79.64   5 35.615 0.2869 172.0, 388.0 -0.41
BXD89 m 149.0 42.973   4 21.486 0.2884 100.0, 188.0 -1.5
BXD90 m 207.5 19.841   4 9.9205 0.0956 182.0, 229.0 -1.01
BXD95 m 358.2 59.79   5 26.74 0.1669 305.0, 454.0 0.27
BXD98 m 584.8 24.397   5 10.911 0.0417 544.0, 600.0 2.2
BXD99 m 395.8 70.88   5 31.698 0.1791 275.0, 462.0 0.59
C57BL/6J m 266.5 60.54   4 30.272 0.2272 214.0, 353.0 -0.5
DBA/2J m 197.0 40.447   3 23.352 0.2053 167.0, 243.0 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 262.6 30.7668796594 323.3078852653 201.8921147347
BXD100 m 292.6 30.7668796594 353.3078852653 231.8921147347
BXD101 m 196.0 34.398417187 263.8734791117 128.1265208883
BXD11 m 253.0 30.7668796594 313.7078852653 192.2921147347
BXD12 m 190.6 30.7668796594 251.3078852653 129.8921147347
BXD16 m 388.2 30.7668796594 448.9078852653 327.4921147347
BXD2 m 187.6 30.7668796594 248.3078852653 126.8921147347
BXD27 m 489.75 34.398417187 557.6234791117 421.8765208883
BXD32 m 308.0 39.7198708452 386.373542872 229.626457128
BXD34 m 214.8 30.7668796594 275.5078852653 154.0921147347
BXD39 m 534.8 30.7668796594 595.5078852653 474.0921147347
BXD40 m 239.75 34.398417187 307.6234791117 171.8765208883
BXD43 m 353.6666666667 39.7198708452 432.0402095386 275.2931237947
BXD44 m 573.75 34.398417187 641.6234791117 505.8765208883
BXD48 m 371.25 34.398417187 439.1234791117 303.3765208883
BXD48a m 390.6666666667 39.7198708452 469.0402095386 312.2931237947
BXD49 m 195.5 34.398417187 263.3734791117 127.6265208883
BXD50 m 223.2 30.7668796594 283.9078852653 162.4921147347
BXD53 m 317.0 30.7668796594 377.7078852653 256.2921147347
BXD55 m 173.75 34.398417187 241.6234791117 105.8765208883
BXD56 m 324.5 34.398417187 392.3734791117 256.6265208883
BXD6 m 235.8 30.7668796594 296.5078852653 175.0921147347
BXD60 m 312.4 30.7668796594 373.1078852653 251.6921147347
BXD61 m 243.4 30.7668796594 304.1078852653 182.6921147347
BXD62 m 312.5 34.398417187 380.3734791117 244.6265208883
BXD63 m 529.0 34.398417187 596.8734791117 461.1265208883
BXD64 m 475.5 34.398417187 543.3734791117 407.6265208883
BXD65 m 325.5 34.398417187 393.3734791117 257.6265208883
BXD65a m 383.5 34.398417187 451.3734791117 315.6265208883
BXD66 m 178.25 34.398417187 246.1234791117 110.3765208883
BXD67 m 381.8 30.7668796594 442.5078852653 321.0921147347
BXD68 m 315.0 34.398417187 382.8734791117 247.1265208883
BXD69 m 577.0 30.7668796594 637.7078852653 516.2921147347
BXD70 m 248.5 34.398417187 316.3734791117 180.6265208883
BXD71 m 504.0 39.7198708452 582.373542872 425.626457128
BXD73 m 255.4 30.7668796594 316.1078852653 194.6921147347
BXD73a m 244.25 34.398417187 312.1234791117 176.3765208883
BXD73b m 235.8 30.7668796594 296.5078852653 175.0921147347
BXD75 m 316.6 30.7668796594 377.3078852653 255.8921147347
BXD77 m 374.6 30.7668796594 435.3078852653 313.8921147347
BXD79 m 366.2 30.7668796594 426.9078852653 305.4921147347
BXD8 m 210.0 30.7668796594 270.7078852653 149.2921147347
BXD81 m 430.0 34.398417187 497.8734791117 362.1265208883
BXD83 m 257.25 34.398417187 325.1234791117 189.3765208883
BXD84 m 531.6666666667 39.7198708452 610.0402095386 453.2931237947
BXD85 m 440.0 34.398417187 507.8734791117 372.1265208883
BXD87 m 277.6 30.7668796594 338.3078852653 216.8921147347
BXD89 m 149.0 34.398417187 216.8734791117 81.1265208883
BXD90 m 207.5 34.398417187 275.3734791117 139.6265208883
BXD95 m 358.2 30.7668796594 418.9078852653 297.4921147347
BXD98 m 584.8 30.7668796594 645.5078852653 524.0921147347
BXD99 m 395.8 30.7668796594 456.5078852653 335.0921147347
C57BL/6J m 266.5 34.398417187 334.3734791117 198.6265208883
DBA/2J m 197.0 39.7198708452 275.373542872 118.626457128




  GWAS USING LINEAR MIXED MODELS