Project measure / variable:   Auwerx1   ogtt_gluc_t90_CD

ID, description, units MPD:111254   ogtt_gluc_t90_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 90 min   [mg/dL]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   55 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 90 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested55 strains
Mean of the strain means200.3   mg/dL
Median of the strain means180.0   mg/dL
SD of the strain means± 74.45
Coefficient of variation (CV)0.3717
Min–max range of strain means105.5   –   483.4   mg/dL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 54 1358899.6119 25164.8076 12.2353 < 0.0001
Residuals 188 386666.1 2056.7346


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 196.4 22.323   5 9.983 0.1137 173.0, 228.0 -0.05
BXD100 m 243.3 46.09   3 26.61 0.1894 199.0, 291.0 0.58
BXD101 m 195.8 23.042   4 11.521 0.1177 174.0, 227.0 -0.06
BXD11 m 178.5 68.06   4 34.031 0.3813 100.0, 265.0 -0.29
BXD12 m 136.2 8.4971   5 3.8 0.0624 128.0, 148.0 -0.86
BXD16 m 266.0 85.08   4 42.54 0.3199 157.0, 359.0 0.88
BXD2 m 167.5 4.6547   4 2.3274 0.0278 161.0, 172.0 -0.44
BXD27 m 317.2 89.26   5 39.918 0.2814 219.0, 428.0 1.57
BXD32 m 141.0 15.875   5 7.0993 0.1126 124.0, 162.0 -0.8
BXD34 m 214.8 52.94   4 26.471 0.2465 142.0, 255.0 0.19
BXD39 m 277.8 34.245   5 15.315 0.1233 233.0, 321.0 1.04
BXD40 m 160.8 24.405   4 12.202 0.1518 137.0, 194.0 -0.53
BXD43 m 245.5 29.715   4 14.858 0.121 210.0, 279.0 0.61
BXD44 m 446.2 100.5   4 50.27 0.2253 337.0, 575.0 3.3
BXD48 m 180.0 20.248   4 10.124 0.1125 153.0, 202.0 -0.27
BXD48a m 199.6 21.698   5 9.7036 0.1087 165.0, 219.0 -0.01
BXD49 m 159.0 8.165   4 4.0825 0.0514 147.0, 165.0 -0.55
BXD50 m 229.2 39.635   4 19.817 0.1729 195.0, 278.0 0.39
BXD53 m 133.6 25.046   5 11.201 0.1875 97.0, 164.0 -0.9
BXD55 m 133.8 15.418   5 6.8949 0.1152 113.0, 151.0 -0.89
BXD56 m 221.4 69.41   5 31.04 0.3135 162.0, 327.0 0.28
BXD6 m 147.2 17.838   5 7.9775 0.1212 127.0, 173.0 -0.71
BXD60 m 150.2 38.713   5 17.313 0.2577 94.0, 194.0 -0.67
BXD61 m 159.7 5.0332   3 2.9059 0.0315 155.0, 165.0 -0.55
BXD62 m 141.8 21.593   4 10.796 0.1523 124.0, 171.0 -0.79
BXD63 m 294.8 48.577   5 21.724 0.1648 237.0, 364.0 1.27
BXD64 m 212.5 73.69   4 36.843 0.3468 137.0, 310.0 0.16
BXD65 m 244.8 69.0   4 34.5 0.2819 184.0, 344.0 0.6
BXD65a m 297.2 123.6   5 55.28 0.4159 223.0, 516.0 1.3
BXD65b m 213.0 36.824   4 18.412 0.1729 166.0, 256.0 0.17
BXD66 m 147.0 15.188   4 7.5939 0.1033 126.0, 162.0 -0.72
BXD67 m 165.0 25.524   5 11.415 0.1547 147.0, 203.0 -0.47
BXD68 m 197.2 29.423   5 13.158 0.1492 156.0, 221.0 -0.04
BXD69 m 483.4 90.34   5 40.402 0.1869 373.0, 600.0 3.8
BXD70 m 109.0 27.142   4 13.571 0.249 76.0, 142.0 -1.23
BXD71 m 250.2 19.28   5 8.6221 0.0771 220.0, 267.0 0.67
BXD73 m 196.5 38.206   4 19.103 0.1944 169.0, 251.0 -0.05
BXD73a m 179.5 13.329   4 6.6646 0.0743 165.0, 194.0 -0.28
BXD73b m 231.2 27.49   5 12.294 0.1189 189.0, 255.0 0.42
BXD75 m 159.4 26.197   5 11.716 0.1643 136.0, 203.0 -0.55
BXD77 m 179.8 31.483   5 14.08 0.1751 164.0, 236.0 -0.28
BXD79 m 182.2 23.7   5 10.599 0.1301 149.0, 210.0 -0.24
BXD8 m 125.8 28.779   4 14.39 0.2289 86.0, 154.0 -1.0
BXD81 m 127.5 16.683   4 8.3417 0.1308 112.0, 148.0 -0.98
BXD83 m 148.3 8.6217   3 4.9777 0.0581 139.0, 156.0 -0.7
BXD84 m 207.4 31.19   5 13.948 0.1504 165.0, 245.0 0.1
BXD85 m 325.6 59.68   5 26.688 0.1833 237.0, 399.0 1.68
BXD87 m 165.2 22.32   5 9.982 0.1351 135.0, 191.0 -0.47
BXD89 m 122.2 6.8007   4 3.4004 0.0556 113.0, 129.0 -1.05
BXD90 m 122.2 16.215   4 8.1074 0.1326 108.0, 140.0 -1.05
BXD95 m 193.0 19.883   4 9.9415 0.103 177.0, 222.0 -0.1
BXD98 m 258.2 77.14   5 34.498 0.2988 188.0, 389.0 0.78
BXD99 m 174.0 32.109   5 14.36 0.1845 141.0, 217.0 -0.35
C57BL/6J m 155.5 20.207   4 10.104 0.13 135.0, 182.0 -0.6
DBA/2J m 105.5 29.49   4 14.745 0.2795 85.0, 149.0 -1.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 196.4 20.2816891529 236.4089315303 156.3910684697
BXD100 m 243.3333333333 26.1835481073 294.9846418389 191.6820248278
BXD101 m 195.75 22.6756178222 240.4813453045 151.0186546955
BXD11 m 178.5 22.6756178222 223.2313453045 133.7686546955
BXD12 m 136.2 20.2816891529 176.2089315303 96.1910684697
BXD16 m 266.0 22.6756178222 310.7313453045 221.2686546955
BXD2 m 167.5 22.6756178222 212.2313453045 122.7686546955
BXD27 m 317.2 20.2816891529 357.2089315303 277.1910684697
BXD32 m 141.0 20.2816891529 181.0089315303 100.9910684697
BXD34 m 214.75 22.6756178222 259.4813453045 170.0186546955
BXD39 m 277.8 20.2816891529 317.8089315303 237.7910684697
BXD40 m 160.75 22.6756178222 205.4813453045 116.0186546955
BXD43 m 245.5 22.6756178222 290.2313453045 200.7686546955
BXD44 m 446.25 22.6756178222 490.9813453045 401.5186546955
BXD48 m 180.0 22.6756178222 224.7313453045 135.2686546955
BXD48a m 199.6 20.2816891529 239.6089315303 159.5910684697
BXD49 m 159.0 22.6756178222 203.7313453045 114.2686546955
BXD50 m 229.25 22.6756178222 273.9813453045 184.5186546955
BXD53 m 133.6 20.2816891529 173.6089315303 93.5910684697
BXD55 m 133.8 20.2816891529 173.8089315303 93.7910684697
BXD56 m 221.4 20.2816891529 261.4089315303 181.3910684697
BXD6 m 147.2 20.2816891529 187.2089315303 107.1910684697
BXD60 m 150.2 20.2816891529 190.2089315303 110.1910684697
BXD61 m 159.6666666667 26.1835481073 211.3179751722 108.0153581611
BXD62 m 141.75 22.6756178222 186.4813453045 97.0186546955
BXD63 m 294.8 20.2816891529 334.8089315303 254.7910684697
BXD64 m 212.5 22.6756178222 257.2313453045 167.7686546955
BXD65 m 244.75 22.6756178222 289.4813453045 200.0186546955
BXD65a m 297.2 20.2816891529 337.2089315303 257.1910684697
BXD65b m 213.0 22.6756178222 257.7313453045 168.2686546955
BXD66 m 147.0 22.6756178222 191.7313453045 102.2686546955
BXD67 m 165.0 20.2816891529 205.0089315303 124.9910684697
BXD68 m 197.2 20.2816891529 237.2089315303 157.1910684697
BXD69 m 483.4 20.2816891529 523.4089315303 443.3910684697
BXD70 m 109.0 22.6756178222 153.7313453045 64.2686546955
BXD71 m 250.2 20.2816891529 290.2089315303 210.1910684697
BXD73 m 196.5 22.6756178222 241.2313453045 151.7686546955
BXD73a m 179.5 22.6756178222 224.2313453045 134.7686546955
BXD73b m 231.2 20.2816891529 271.2089315303 191.1910684697
BXD75 m 159.4 20.2816891529 199.4089315303 119.3910684697
BXD77 m 179.8 20.2816891529 219.8089315303 139.7910684697
BXD79 m 182.2 20.2816891529 222.2089315303 142.1910684697
BXD8 m 125.75 22.6756178222 170.4813453045 81.0186546955
BXD81 m 127.5 22.6756178222 172.2313453045 82.7686546955
BXD83 m 148.3333333333 26.1835481073 199.9846418389 96.6820248278
BXD84 m 207.4 20.2816891529 247.4089315303 167.3910684697
BXD85 m 325.6 20.2816891529 365.6089315303 285.5910684697
BXD87 m 165.2 20.2816891529 205.2089315303 125.1910684697
BXD89 m 122.25 22.6756178222 166.9813453045 77.5186546955
BXD90 m 122.25 22.6756178222 166.9813453045 77.5186546955
BXD95 m 193.0 22.6756178222 237.7313453045 148.2686546955
BXD98 m 258.2 20.2816891529 298.2089315303 218.1910684697
BXD99 m 174.0 20.2816891529 214.0089315303 133.9910684697
C57BL/6J m 155.5 22.6756178222 200.2313453045 110.7686546955
DBA/2J m 105.5 22.6756178222 150.2313453045 60.7686546955




  GWAS USING LINEAR MIXED MODELS