Project measure / variable:   Auwerx1   ogtt_gluc_t45_CD

ID, description, units MPD:111250   ogtt_gluc_t45_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 45 min   [mg/dL]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 45 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means278.7   mg/dL
Median of the strain means261.8   mg/dL
SD of the strain means± 87.56
Coefficient of variation (CV)0.3142
Min–max range of strain means165.2   –   527.2   mg/dL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 2140083.152 38215.7706 13.078 < 0.0001
Residuals 198 578582.55 2922.1341


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 226.6 18.147   5 8.1154 0.0801 200.0, 251.0 -0.59
BXD100 m 404.0 18.52   3 10.693 0.0458 383.0, 418.0 1.43
BXD101 m 264.0 20.769   4 10.384 0.0787 235.0, 280.0 -0.17
BXD11 m 216.0 68.33   4 34.164 0.3163 117.0, 269.0 -0.72
BXD12 m 181.4 18.229   5 8.1523 0.1005 153.0, 202.0 -1.11
BXD16 m 400.0 100.5   4 50.27 0.2514 266.0, 502.0 1.39
BXD2 m 215.8 12.285   4 6.1424 0.0569 201.0, 230.0 -0.72
BXD27 m 512.8 87.0   5 38.909 0.1697 401.0, 600.0 2.67
BXD32 m 256.2 31.18   5 13.944 0.1217 213.0, 300.0 -0.26
BXD34 m 350.2 65.01   4 32.507 0.1856 268.0, 423.0 0.82
BXD39 m 381.2 61.71   5 27.6 0.1619 302.0, 469.0 1.17
BXD40 m 262.8 62.7   4 31.349 0.2386 189.0, 337.0 -0.18
BXD43 m 390.2 32.928   4 16.464 0.0844 341.0, 410.0 1.27
BXD44 m 506.0 83.76   9 27.921 0.1655 389.0, 600.0 2.6
BXD45 m 237.8 17.231   4 8.6156 0.0725 221.0, 255.0 -0.47
BXD48 m 310.2 50.89   4 25.444 0.164 252.0, 375.0 0.36
BXD48a m 285.8 48.572   5 21.722 0.1699 240.0, 360.0 0.08
BXD49 m 239.0 26.671   4 13.335 0.1116 214.0, 273.0 -0.45
BXD50 m 261.8 26.713   4 13.356 0.1021 224.0, 283.0 -0.19
BXD51 m 202.0 42.763   4 21.381 0.2117 163.0, 247.0 -0.88
BXD53 m 241.4 52.17   5 23.329 0.2161 183.0, 305.0 -0.43
BXD55 m 197.4 17.841   5 7.9787 0.0904 177.0, 217.0 -0.93
BXD56 m 305.4 100.7   5 45.043 0.3298 213.0, 463.0 0.31
BXD6 m 224.0 22.627   5 10.119 0.101 198.0, 257.0 -0.62
BXD60 m 219.8 71.22   5 31.849 0.324 111.0, 290.0 -0.67
BXD61 m 201.7 32.96   3 19.029 0.1634 166.0, 231.0 -0.88
BXD62 m 190.7 2.0817   3 1.2019 0.0109 189.0, 193.0 -1.0
BXD63 m 358.8 53.19   5 23.787 0.1482 285.0, 433.0 0.92
BXD64 m 267.8 54.93   4 27.466 0.2052 229.0, 346.0 -0.12
BXD65 m 331.2 102.7   4 51.35 0.31 215.0, 461.0 0.6
BXD65a m 361.4 78.39   5 35.058 0.2169 302.0, 489.0 0.94
BXD65b m 279.2 48.877   4 24.438 0.175 221.0, 328.0 0.01
BXD66 m 224.8 53.46   4 26.728 0.2378 151.0, 279.0 -0.62
BXD67 m 265.8 31.444   5 14.062 0.1183 237.0, 318.0 -0.15
BXD68 m 317.4 76.13   5 34.048 0.2399 253.0, 445.0 0.44
BXD69 m 527.2 103.1   5 46.117 0.1956 357.0, 600.0 2.84
BXD70 m 165.2 61.79   4 30.893 0.3739 107.0, 252.0 -1.3
BXD71 m 367.0 46.179   5 20.652 0.1258 293.0, 407.0 1.01
BXD73 m 200.5 6.8557   4 3.4278 0.0342 194.0, 209.0 -0.89
BXD73a m 260.5 36.991   4 18.495 0.142 207.0, 290.0 -0.21
BXD73b m 307.8 34.434   5 15.399 0.1119 261.0, 356.0 0.33
BXD75 m 277.4 47.406   5 21.2 0.1709 209.0, 334.0 -0.01
BXD77 m 311.8 37.259   5 16.663 0.1195 278.0, 354.0 0.38
BXD79 m 199.8 47.13   5 21.077 0.2359 141.0, 252.0 -0.9
BXD8 m 198.8 23.329   4 11.665 0.1174 178.0, 229.0 -0.91
BXD81 m 191.0 38.738   4 19.369 0.2028 136.0, 221.0 -1.0
BXD83 m 175.3 16.258   3 9.3868 0.0927 161.0, 193.0 -1.18
BXD84 m 244.2 33.507   5 14.985 0.1372 203.0, 291.0 -0.39
BXD85 m 431.4 55.92   5 25.009 0.1296 361.0, 494.0 1.74
BXD87 m 247.6 37.447   5 16.747 0.1512 203.0, 306.0 -0.35
BXD89 m 197.5 6.5574   4 3.2787 0.0332 188.0, 203.0 -0.93
BXD90 m 196.5 24.772   4 12.386 0.1261 171.0, 228.0 -0.94
BXD95 m 273.0 28.202   4 14.101 0.1033 239.0, 308.0 -0.06
BXD98 m 363.0 73.55   5 32.892 0.2026 252.0, 445.0 0.96
BXD99 m 266.6 48.526   5 21.702 0.182 210.0, 343.0 -0.14
C57BL/6J m 225.5 50.41   4 25.207 0.2236 191.0, 300.0 -0.61
DBA/2J m 166.5 36.901   4 18.45 0.2216 121.0, 198.0 -1.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 226.6 24.1749212653 274.2733672604 178.9266327396
BXD100 m 404.0 31.2096891521 465.5460524858 342.4539475143
BXD101 m 264.0 27.0283836499 317.3004449553 210.6995550447
BXD11 m 216.0 27.0283836499 269.3004449553 162.6995550447
BXD12 m 181.4 24.1749212653 229.0733672604 133.7266327396
BXD16 m 400.0 27.0283836499 453.3004449553 346.6995550447
BXD2 m 215.75 27.0283836499 269.0504449553 162.4495550447
BXD27 m 512.8 24.1749212653 560.4733672604 465.1266327396
BXD32 m 256.2 24.1749212653 303.8733672604 208.5266327396
BXD34 m 350.25 27.0283836499 403.5504449553 296.9495550447
BXD39 m 381.2 24.1749212653 428.8733672604 333.5266327396
BXD40 m 262.75 27.0283836499 316.0504449553 209.4495550447
BXD43 m 390.25 27.0283836499 443.5504449553 336.9495550447
BXD44 m 506.0 18.0189224333 541.5336299702 470.4663700298
BXD45 m 237.75 27.0283836499 291.0504449553 184.4495550447
BXD48 m 310.25 27.0283836499 363.5504449553 256.9495550447
BXD48a m 285.8 24.1749212653 333.4733672604 238.1266327396
BXD49 m 239.0 27.0283836499 292.3004449553 185.6995550447
BXD50 m 261.75 27.0283836499 315.0504449553 208.4495550447
BXD51 m 202.0 27.0283836499 255.3004449553 148.6995550447
BXD53 m 241.4 24.1749212653 289.0733672604 193.7266327396
BXD55 m 197.4 24.1749212653 245.0733672604 149.7266327396
BXD56 m 305.4 24.1749212653 353.0733672604 257.7266327396
BXD6 m 224.0 24.1749212653 271.6733672604 176.3266327396
BXD60 m 219.8 24.1749212653 267.4733672604 172.1266327396
BXD61 m 201.6666666667 31.2096891521 263.2127191524 140.1206141809
BXD62 m 190.6666666667 31.2096891521 252.2127191524 129.1206141809
BXD63 m 358.8 24.1749212653 406.4733672604 311.1266327396
BXD64 m 267.75 27.0283836499 321.0504449553 214.4495550447
BXD65 m 331.25 27.0283836499 384.5504449553 277.9495550447
BXD65a m 361.4 24.1749212653 409.0733672604 313.7266327396
BXD65b m 279.25 27.0283836499 332.5504449553 225.9495550447
BXD66 m 224.75 27.0283836499 278.0504449553 171.4495550447
BXD67 m 265.8 24.1749212653 313.4733672604 218.1266327396
BXD68 m 317.4 24.1749212653 365.0733672604 269.7266327396
BXD69 m 527.2 24.1749212653 574.8733672604 479.5266327396
BXD70 m 165.25 27.0283836499 218.5504449553 111.9495550447
BXD71 m 367.0 24.1749212653 414.6733672604 319.3266327396
BXD73 m 200.5 27.0283836499 253.8004449553 147.1995550447
BXD73a m 260.5 27.0283836499 313.8004449553 207.1995550447
BXD73b m 307.8 24.1749212653 355.4733672604 260.1266327396
BXD75 m 277.4 24.1749212653 325.0733672604 229.7266327396
BXD77 m 311.8 24.1749212653 359.4733672604 264.1266327396
BXD79 m 199.8 24.1749212653 247.4733672604 152.1266327396
BXD8 m 198.75 27.0283836499 252.0504449553 145.4495550447
BXD81 m 191.0 27.0283836499 244.3004449553 137.6995550447
BXD83 m 175.3333333333 31.2096891521 236.8793858191 113.7872808476
BXD84 m 244.2 24.1749212653 291.8733672604 196.5266327396
BXD85 m 431.4 24.1749212653 479.0733672604 383.7266327396
BXD87 m 247.6 24.1749212653 295.2733672604 199.9266327396
BXD89 m 197.5 27.0283836499 250.8004449553 144.1995550447
BXD90 m 196.5 27.0283836499 249.8004449553 143.1995550447
BXD95 m 273.0 27.0283836499 326.3004449553 219.6995550447
BXD98 m 363.0 24.1749212653 410.6733672604 315.3266327396
BXD99 m 266.6 24.1749212653 314.2733672604 218.9266327396
C57BL/6J m 225.5 27.0283836499 278.8004449553 172.1995550447
DBA/2J m 166.5 27.0283836499 219.8004449553 113.1995550447




  GWAS USING LINEAR MIXED MODELS