Project measure / variable:   Auwerx1   ogtt_gluc_t30_HFD

ID, description, units MPD:111249   ogtt_gluc_t30_HFD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min   [mg/dL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means386.7   mg/dL
Median of the strain means373.1   mg/dL
SD of the strain means± 93.47
Coefficient of variation (CV)0.2417
Min–max range of strain means228.4   –   581.0   mg/dL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 2227198.7503 40494.5227 8.293 < 0.0001
Residuals 192 937529.1167 4882.9641


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 447.8 17.384   5 7.7743 0.0388 420.0, 463.0 0.65
BXD100 m 378.4 72.29   5 32.329 0.191 299.0, 465.0 -0.09
BXD101 m 259.5 37.036   4 18.518 0.1427 223.0, 311.0 -1.36
BXD11 m 305.2 86.51   5 38.689 0.2835 219.0, 437.0 -0.87
BXD12 m 333.0 50.62   5 22.638 0.152 269.0, 402.0 -0.57
BXD16 m 502.0 94.46   5 42.243 0.1882 382.0, 598.0 1.23
BXD2 m 228.4 28.571   5 12.777 0.1251 186.0, 261.0 -1.69
BXD27 m 490.2 69.77   4 34.884 0.1423 435.0, 583.0 1.11
BXD32 m 299.7 110.3   3 63.69 0.3681 233.0, 427.0 -0.93
BXD34 m 373.2 56.05   5 25.065 0.1502 276.0, 416.0 -0.14
BXD39 m 513.0 50.41   5 22.546 0.0983 471.0, 600.0 1.35
BXD40 m 412.2 40.607   4 20.303 0.0985 356.0, 443.0 0.27
BXD43 m 487.0 31.575   3 18.23 0.0648 464.0, 523.0 1.07
BXD44 m 581.0 23.943   9 7.9809 0.0412 541.0, 600.0 2.08
BXD45 m 286.8 24.418   4 12.209 0.0852 252.0, 309.0 -1.07
BXD48 m 477.2 87.03   4 43.517 0.1824 391.0, 585.0 0.97
BXD48a m 445.3 120.1   3 69.36 0.2698 308.0, 531.0 0.63
BXD49 m 272.5 22.038   4 11.019 0.0809 240.0, 289.0 -1.22
BXD50 m 290.2 35.905   5 16.057 0.1237 254.0, 340.0 -1.03
BXD51 m 358.2 23.429   4 11.714 0.0654 325.0, 377.0 -0.3
BXD53 m 465.8 87.49   5 39.127 0.1878 356.0, 600.0 0.85
BXD55 m 251.2 32.816   4 16.408 0.1306 206.0, 280.0 -1.45
BXD56 m 421.2 62.11   4 31.055 0.1474 369.0, 511.0 0.37
BXD6 m 373.0 58.2   5 26.029 0.156 313.0, 439.0 -0.15
BXD60 m 321.0 24.87   5 11.122 0.0775 287.0, 348.0 -0.7
BXD61 m 293.8 85.42   5 38.201 0.2907 214.0, 438.0 -0.99
BXD62 m 364.0 92.48   4 46.24 0.2541 256.0, 473.0 -0.24
BXD63 m 505.8 69.94   4 34.972 0.1383 439.0, 596.0 1.27
BXD64 m 468.0 108.3   4 54.17 0.2315 306.0, 534.0 0.87
BXD65 m 396.5 159.1   4 79.57 0.4014 240.0, 551.0 0.11
BXD65a m 398.0 39.674   4 19.837 0.0997 362.0, 453.0 0.12
BXD66 m 246.2 23.571   4 11.785 0.0957 215.0, 270.0 -1.5
BXD67 m 397.2 30.475   5 13.629 0.0767 375.0, 446.0 0.11
BXD68 m 468.5 47.276   4 23.638 0.1009 422.0, 525.0 0.88
BXD69 m 555.4 62.05   5 27.748 0.1117 473.0, 600.0 1.81
BXD70 m 340.0 99.98   4 49.988 0.294 237.0, 470.0 -0.5
BXD71 m 528.0 110.3   3 63.69 0.2089 401.0, 600.0 1.51
BXD73 m 312.6 82.77   5 37.014 0.2648 200.0, 431.0 -0.79
BXD73a m 285.8 53.78   4 26.89 0.1882 244.0, 364.0 -1.08
BXD73b m 279.2 92.17   5 41.218 0.3301 182.0, 397.0 -1.15
BXD75 m 339.6 61.25   5 27.391 0.1804 284.0, 436.0 -0.5
BXD77 m 473.0 70.87   5 31.694 0.1498 348.0, 519.0 0.92
BXD79 m 337.6 81.59   5 36.486 0.2417 233.0, 457.0 -0.52
BXD8 m 291.0 47.896   5 21.42 0.1646 255.0, 369.0 -1.02
BXD81 m 493.5 69.04   4 34.522 0.1399 450.0, 596.0 1.14
BXD83 m 372.5 114.6   4 57.3 0.3076 256.0, 488.0 -0.15
BXD84 m 495.3 92.05   3 53.14 0.1858 427.0, 600.0 1.16
BXD85 m 502.2 122.6   4 61.28 0.244 346.0, 600.0 1.24
BXD87 m 366.2 64.33   5 28.769 0.1757 272.0, 422.0 -0.22
BXD89 m 296.0 74.01   4 37.007 0.25 195.0, 372.0 -0.97
BXD90 m 334.5 16.422   4 8.2108 0.0491 317.0, 349.0 -0.56
BXD95 m 430.6 69.22   5 30.957 0.1608 348.0, 508.0 0.47
BXD98 m 536.2 70.28   5 31.43 0.1311 427.0, 600.0 1.6
BXD99 m 419.2 71.7   5 32.066 0.171 345.0, 511.0 0.35
C57BL/6J m 302.0 60.57   4 30.285 0.2006 263.0, 392.0 -0.91
DBA/2J m 251.3 61.98   3 35.783 0.2466 180.0, 292.0 -1.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 447.8 31.250485274 509.4383475064 386.1616524936
BXD100 m 378.4 31.250485274 440.0383475064 316.7616524936
BXD101 m 259.5 34.9391047013 328.4137675225 190.5862324775
BXD11 m 305.2 31.250485274 366.8383475064 243.5616524936
BXD12 m 333.0 31.250485274 394.6383475064 271.3616524936
BXD16 m 502.0 31.250485274 563.6383475064 440.3616524936
BXD2 m 228.4 31.250485274 290.0383475064 166.7616524936
BXD27 m 490.25 34.9391047013 559.1637675225 421.3362324775
BXD32 m 299.6666666667 40.344203009 379.2414311266 220.0919022067
BXD34 m 373.2 31.250485274 434.8383475064 311.5616524936
BXD39 m 513.0 31.250485274 574.6383475064 451.3616524936
BXD40 m 412.25 34.9391047013 481.1637675225 343.3362324775
BXD43 m 487.0 40.344203009 566.57476446 407.42523554
BXD44 m 581.0 23.2927364675 626.9425116817 535.0574883183
BXD45 m 286.75 34.9391047013 355.6637675225 217.8362324775
BXD48 m 477.25 34.9391047013 546.1637675225 408.3362324775
BXD48a m 445.3333333333 40.344203009 524.9080977933 365.7585688734
BXD49 m 272.5 34.9391047013 341.4137675225 203.5862324775
BXD50 m 290.2 31.250485274 351.8383475064 228.5616524936
BXD51 m 358.25 34.9391047013 427.1637675225 289.3362324775
BXD53 m 465.8 31.250485274 527.4383475064 404.1616524936
BXD55 m 251.25 34.9391047013 320.1637675225 182.3362324775
BXD56 m 421.25 34.9391047013 490.1637675225 352.3362324775
BXD6 m 373.0 31.250485274 434.6383475064 311.3616524936
BXD60 m 321.0 31.250485274 382.6383475064 259.3616524936
BXD61 m 293.8 31.250485274 355.4383475064 232.1616524936
BXD62 m 364.0 34.9391047013 432.9137675225 295.0862324775
BXD63 m 505.75 34.9391047013 574.6637675225 436.8362324775
BXD64 m 468.0 34.9391047013 536.9137675225 399.0862324775
BXD65 m 396.5 34.9391047013 465.4137675225 327.5862324775
BXD65a m 398.0 34.9391047013 466.9137675225 329.0862324775
BXD66 m 246.25 34.9391047013 315.1637675225 177.3362324775
BXD67 m 397.2 31.250485274 458.8383475064 335.5616524936
BXD68 m 468.5 34.9391047013 537.4137675225 399.5862324775
BXD69 m 555.4 31.250485274 617.0383475064 493.7616524936
BXD70 m 340.0 34.9391047013 408.9137675225 271.0862324775
BXD71 m 528.0 40.344203009 607.57476446 448.42523554
BXD73 m 312.6 31.250485274 374.2383475064 250.9616524936
BXD73a m 285.75 34.9391047013 354.6637675225 216.8362324775
BXD73b m 279.2 31.250485274 340.8383475064 217.5616524936
BXD75 m 339.6 31.250485274 401.2383475064 277.9616524936
BXD77 m 473.0 31.250485274 534.6383475064 411.3616524936
BXD79 m 337.6 31.250485274 399.2383475064 275.9616524936
BXD8 m 291.0 31.250485274 352.6383475064 229.3616524936
BXD81 m 493.5 34.9391047013 562.4137675225 424.5862324775
BXD83 m 372.5 34.9391047013 441.4137675225 303.5862324775
BXD84 m 495.3333333333 40.344203009 574.9080977933 415.7585688734
BXD85 m 502.25 34.9391047013 571.1637675225 433.3362324775
BXD87 m 366.2 31.250485274 427.8383475064 304.5616524936
BXD89 m 296.0 34.9391047013 364.9137675225 227.0862324775
BXD90 m 334.5 34.9391047013 403.4137675225 265.5862324775
BXD95 m 430.6 31.250485274 492.2383475064 368.9616524936
BXD98 m 536.2 31.250485274 597.8383475064 474.5616524936
BXD99 m 419.2 31.250485274 480.8383475064 357.5616524936
C57BL/6J m 302.0 34.9391047013 370.9137675225 233.0862324775
DBA/2J m 251.3333333333 40.344203009 330.9080977933 171.7585688734




  GWAS USING LINEAR MIXED MODELS