Project measure / variable:   Auwerx1   ogtt_gluc_t30_CD

ID, description, units MPD:111248   ogtt_gluc_t30_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min   [mg/dL]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means296.0   mg/dL
Median of the strain means280.0   mg/dL
SD of the strain means± 82.39
Coefficient of variation (CV)0.2784
Min–max range of strain means179.0   –   533.8   mg/dL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 1830197.8635 32682.1047 10.507 < 0.0001
Residuals 199 618989.2889 3110.4989


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 245.8 36.348   5 16.255 0.1479 203.0, 301.0 -0.61
BXD100 m 439.0 55.83   3 32.234 0.1272 387.0, 498.0 1.74
BXD101 m 302.8 24.703   4 12.352 0.0816 268.0, 325.0 0.08
BXD11 m 227.8 48.74   4 24.37 0.214 157.0, 261.0 -0.83
BXD12 m 209.0 23.195   5 10.373 0.111 178.0, 234.0 -1.06
BXD16 m 375.0 67.09   4 33.546 0.1789 283.0, 443.0 0.96
BXD2 m 220.2 27.621   4 13.81 0.1254 200.0, 261.0 -0.92
BXD27 m 503.8 75.12   5 33.597 0.1491 431.0, 589.0 2.52
BXD32 m 297.4 28.893   5 12.921 0.0972 268.0, 334.0 0.02
BXD34 m 376.2 65.58   4 32.791 0.1743 301.0, 461.0 0.97
BXD39 m 381.4 85.04   5 38.03 0.223 263.0, 487.0 1.04
BXD40 m 294.2 63.07   4 31.534 0.2143 225.0, 374.0 -0.02
BXD43 m 431.5 40.353   4 20.176 0.0935 378.0, 471.0 1.64
BXD44 m 470.6 87.69   9 29.23 0.1864 334.0, 600.0 2.12
BXD45 m 280.2 29.848   4 14.924 0.1065 256.0, 321.0 -0.19
BXD48 m 340.0 62.08   4 31.04 0.1826 287.0, 421.0 0.53
BXD48a m 304.4 29.467   5 13.178 0.0968 276.0, 351.0 0.1
BXD49 m 266.2 42.288   4 21.144 0.1588 220.0, 306.0 -0.36
BXD50 m 280.0 18.403   4 9.2014 0.0657 256.0, 300.0 -0.19
BXD51 m 222.2 48.404   4 24.202 0.2178 162.0, 280.0 -0.9
BXD53 m 287.2 22.543   5 10.082 0.0785 265.0, 317.0 -0.11
BXD55 m 217.8 14.096   5 6.304 0.0647 202.0, 233.0 -0.95
BXD56 m 295.0 105.8   5 47.318 0.3587 206.0, 468.0 -0.01
BXD6 m 268.2 23.08   5 10.322 0.0861 243.0, 303.0 -0.34
BXD60 m 235.6 61.62   5 27.558 0.2616 126.0, 271.0 -0.73
BXD61 m 285.7 136.4   3 78.73 0.4773 175.0, 438.0 -0.12
BXD62 m 188.5 12.477   4 6.2383 0.0662 172.0, 200.0 -1.3
BXD63 m 379.8 44.645   5 19.966 0.1175 321.0, 442.0 1.02
BXD64 m 263.2 54.32   4 27.161 0.2064 190.0, 311.0 -0.4
BXD65 m 328.0 90.38   4 45.19 0.2756 199.0, 404.0 0.39
BXD65a m 365.4 86.08   5 38.498 0.2356 281.0, 510.0 0.84
BXD65b m 243.0 62.23   4 31.115 0.2561 180.0, 323.0 -0.64
BXD66 m 223.8 31.973   4 15.986 0.1429 183.0, 261.0 -0.88
BXD67 m 301.4 38.507   5 17.221 0.1278 244.0, 338.0 0.07
BXD68 m 385.0 84.34   5 37.719 0.2191 322.0, 530.0 1.08
BXD69 m 533.8 106.3   5 47.536 0.1991 348.0, 600.0 2.89
BXD70 m 201.0 79.57   4 39.785 0.3959 124.0, 311.0 -1.15
BXD71 m 373.0 29.138   5 13.031 0.0781 342.0, 412.0 0.93
BXD73 m 189.0 32.69   4 16.345 0.173 156.0, 228.0 -1.3
BXD73a m 270.5 23.854   4 11.927 0.0882 237.0, 293.0 -0.31
BXD73b m 321.6 32.377   5 14.48 0.1007 280.0, 365.0 0.31
BXD75 m 272.6 57.74   5 25.824 0.2118 211.0, 367.0 -0.28
BXD77 m 335.2 34.73   5 15.532 0.1036 297.0, 387.0 0.48
BXD79 m 196.2 56.33   5 25.192 0.2871 142.0, 256.0 -1.21
BXD8 m 239.0 13.342   4 6.6708 0.0558 222.0, 254.0 -0.69
BXD81 m 228.0 47.096   4 23.548 0.2066 166.0, 268.0 -0.83
BXD83 m 201.0 13.0   3 7.5056 0.0647 193.0, 216.0 -1.15
BXD84 m 266.8 59.94   5 26.806 0.2247 224.0, 371.0 -0.35
BXD85 m 429.0 62.57   5 27.98 0.1458 359.0, 514.0 1.61
BXD87 m 252.8 32.882   5 14.705 0.1301 215.0, 289.0 -0.52
BXD89 m 221.5 16.299   4 8.1496 0.0736 203.0, 238.0 -0.9
BXD90 m 238.2 11.147   4 5.5734 0.0468 229.0, 254.0 -0.7
BXD95 m 285.2 40.36   4 20.18 0.1415 252.0, 344.0 -0.13
BXD98 m 381.2 46.397   5 20.749 0.1217 302.0, 417.0 1.03
BXD99 m 260.4 39.784   5 17.792 0.1528 225.0, 329.0 -0.43
C57BL/6J m 260.5 30.447   4 15.223 0.1169 238.0, 304.0 -0.43
DBA/2J m 179.0 50.15   4 25.077 0.2802 130.0, 240.0 -1.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 245.8 24.9419283101 294.9843987574 196.6156012426
BXD100 m 439.0 32.1998909892 502.4967857603 375.5032142397
BXD101 m 302.75 27.8859235957 357.739829527 247.760170473
BXD11 m 227.75 27.8859235957 282.739829527 172.760170473
BXD12 m 209.0 24.9419283101 258.1843987574 159.8156012426
BXD16 m 375.0 27.8859235957 429.989829527 320.010170473
BXD2 m 220.25 27.8859235957 275.239829527 165.260170473
BXD27 m 503.8 24.9419283101 552.9843987574 454.6156012426
BXD32 m 297.4 24.9419283101 346.5843987574 248.2156012426
BXD34 m 376.25 27.8859235957 431.239829527 321.260170473
BXD39 m 381.4 24.9419283101 430.5843987574 332.2156012426
BXD40 m 294.25 27.8859235957 349.239829527 239.260170473
BXD43 m 431.5 27.8859235957 486.489829527 376.510170473
BXD44 m 470.5555555556 18.5906157305 507.2154419069 433.8956692042
BXD45 m 280.25 27.8859235957 335.239829527 225.260170473
BXD48 m 340.0 27.8859235957 394.989829527 285.010170473
BXD48a m 304.4 24.9419283101 353.5843987574 255.2156012426
BXD49 m 266.25 27.8859235957 321.239829527 211.260170473
BXD50 m 280.0 27.8859235957 334.989829527 225.010170473
BXD51 m 222.25 27.8859235957 277.239829527 167.260170473
BXD53 m 287.2 24.9419283101 336.3843987574 238.0156012426
BXD55 m 217.8 24.9419283101 266.9843987574 168.6156012426
BXD56 m 295.0 24.9419283101 344.1843987574 245.8156012426
BXD6 m 268.2 24.9419283101 317.3843987574 219.0156012426
BXD60 m 235.6 24.9419283101 284.7843987574 186.4156012426
BXD61 m 285.6666666667 32.1998909892 349.1634524269 222.1698809064
BXD62 m 188.5 27.8859235957 243.489829527 133.510170473
BXD63 m 379.8 24.9419283101 428.9843987574 330.6156012426
BXD64 m 263.25 27.8859235957 318.239829527 208.260170473
BXD65 m 328.0 27.8859235957 382.989829527 273.010170473
BXD65a m 365.4 24.9419283101 414.5843987574 316.2156012426
BXD65b m 243.0 27.8859235957 297.989829527 188.010170473
BXD66 m 223.75 27.8859235957 278.739829527 168.760170473
BXD67 m 301.4 24.9419283101 350.5843987574 252.2156012426
BXD68 m 385.0 24.9419283101 434.1843987574 335.8156012426
BXD69 m 533.8 24.9419283101 582.9843987574 484.6156012426
BXD70 m 201.0 27.8859235957 255.989829527 146.010170473
BXD71 m 373.0 24.9419283101 422.1843987574 323.8156012426
BXD73 m 189.0 27.8859235957 243.989829527 134.010170473
BXD73a m 270.5 27.8859235957 325.489829527 215.510170473
BXD73b m 321.6 24.9419283101 370.7843987574 272.4156012426
BXD75 m 272.6 24.9419283101 321.7843987574 223.4156012426
BXD77 m 335.2 24.9419283101 384.3843987574 286.0156012426
BXD79 m 196.2 24.9419283101 245.3843987574 147.0156012426
BXD8 m 239.0 27.8859235957 293.989829527 184.010170473
BXD81 m 228.0 27.8859235957 282.989829527 173.010170473
BXD83 m 201.0 32.1998909892 264.4967857603 137.5032142397
BXD84 m 266.8 24.9419283101 315.9843987574 217.6156012426
BXD85 m 429.0 24.9419283101 478.1843987574 379.8156012426
BXD87 m 252.8 24.9419283101 301.9843987574 203.6156012426
BXD89 m 221.5 27.8859235957 276.489829527 166.510170473
BXD90 m 238.25 27.8859235957 293.239829527 183.260170473
BXD95 m 285.25 27.8859235957 340.239829527 230.260170473
BXD98 m 381.2 24.9419283101 430.3843987574 332.0156012426
BXD99 m 260.4 24.9419283101 309.5843987574 211.2156012426
C57BL/6J m 260.5 27.8859235957 315.489829527 205.510170473
DBA/2J m 179.0 27.8859235957 233.989829527 124.010170473




  GWAS USING LINEAR MIXED MODELS