Project measure / variable:   Auwerx1   ogtt_gluc_t15_HFD

ID, description, units MPD:111247   ogtt_gluc_t15_HFD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min   [mg/dL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure glucose tolerance
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means340.4   mg/dL
Median of the strain means331.6   mg/dL
SD of the strain means± 73.01
Coefficient of variation (CV)0.2145
Min–max range of strain means199.5   –   510.4   mg/dL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 1324861.3564 24088.3883 5.9404 < 0.0001
Residuals 190 770448.481 4054.992


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 306.0 49.754   5 22.251 0.1626 247.0, 358.0 -0.47
BXD100 m 352.4 44.758   5 20.016 0.127 318.0, 429.0 0.16
BXD101 m 212.5 41.613   4 20.807 0.1958 179.0, 267.0 -1.75
BXD11 m 241.2 49.666   5 22.211 0.2059 184.0, 317.0 -1.36
BXD12 m 377.6 61.82   5 27.649 0.1637 317.0, 470.0 0.51
BXD16 m 426.0 74.4   5 33.273 0.1747 332.0, 537.0 1.17
BXD2 m 268.6 43.183   5 19.312 0.1608 206.0, 322.0 -0.98
BXD27 m 387.2 81.34   4 40.67 0.21 284.0, 473.0 0.64
BXD32 m 298.3 104.8   3 60.51 0.3513 230.0, 419.0 -0.58
BXD34 m 338.2 37.546   5 16.791 0.111 295.0, 384.0 -0.03
BXD39 m 510.4 35.823   5 16.021 0.0702 461.0, 552.0 2.33
BXD40 m 322.8 44.947   4 22.474 0.1393 269.0, 379.0 -0.24
BXD43 m 344.7 22.053   3 12.732 0.064 326.0, 369.0 0.06
BXD44 m 488.6 130.7   7 49.383 0.2674 247.0, 600.0 2.03
BXD45 m 277.5 41.203   4 20.601 0.1485 243.0, 337.0 -0.86
BXD48 m 389.5 74.75   4 37.375 0.1919 307.0, 465.0 0.67
BXD48a m 417.7 69.87   3 40.337 0.1673 337.0, 459.0 1.06
BXD49 m 267.0 30.54   4 15.27 0.1144 242.0, 309.0 -1.01
BXD50 m 327.8 21.51   5 9.6198 0.0656 301.0, 355.0 -0.17
BXD51 m 313.0 80.96   4 40.48 0.2587 227.0, 411.0 -0.38
BXD53 m 423.0 74.98   5 33.534 0.1773 365.0, 554.0 1.13
BXD55 m 199.5 22.664   4 11.332 0.1136 173.0, 228.0 -1.93
BXD56 m 311.2 28.605   4 14.303 0.0919 269.0, 332.0 -0.4
BXD6 m 321.8 33.484   5 14.975 0.1041 288.0, 359.0 -0.25
BXD60 m 351.2 42.728   5 19.109 0.1217 288.0, 395.0 0.15
BXD61 m 250.8 39.137   5 17.503 0.156 215.0, 308.0 -1.23
BXD62 m 315.0 56.57   4 28.287 0.1796 231.0, 351.0 -0.35
BXD63 m 439.8 73.53   4 36.766 0.1672 340.0, 517.0 1.36
BXD64 m 358.2 101.3   4 50.64 0.2827 224.0, 439.0 0.24
BXD65 m 379.8 113.8   4 56.89 0.2996 237.0, 494.0 0.54
BXD65a m 326.5 28.29   4 14.145 0.0866 296.0, 353.0 -0.19
BXD66 m 243.2 16.091   4 8.0454 0.0661 232.0, 267.0 -1.33
BXD67 m 363.4 50.33   5 22.507 0.1385 295.0, 423.0 0.32
BXD68 m 406.8 46.914   4 23.457 0.1153 346.0, 456.0 0.91
BXD69 m 465.4 126.8   5 56.7 0.2724 318.0, 600.0 1.71
BXD70 m 333.5 77.69   4 38.843 0.2329 255.0, 408.0 -0.09
BXD71 m 472.0 74.32   3 42.911 0.1575 394.0, 542.0 1.8
BXD73 m 299.8 66.92   5 29.926 0.2232 225.0, 407.0 -0.56
BXD73a m 244.0 22.015   4 11.008 0.0902 225.0, 269.0 -1.32
BXD73b m 240.6 87.51   5 39.136 0.3637 126.0, 323.0 -1.37
BXD75 m 294.6 37.421   5 16.735 0.127 238.0, 330.0 -0.63
BXD77 m 375.6 65.61   5 29.344 0.1747 281.0, 456.0 0.48
BXD79 m 275.8 57.69   5 25.802 0.2092 215.0, 366.0 -0.88
BXD8 m 276.2 52.07   5 23.286 0.1885 211.0, 352.0 -0.88
BXD81 m 433.2 23.894   4 11.947 0.0552 405.0, 461.0 1.27
BXD83 m 340.2 81.8   4 40.899 0.2404 254.0, 422.0 0.0
BXD84 m 357.7 72.61   3 41.922 0.203 308.0, 441.0 0.24
BXD85 m 466.5 88.89   4 44.446 0.1905 352.0, 545.0 1.73
BXD87 m 359.0 29.06   5 12.996 0.0809 322.0, 385.0 0.25
BXD89 m 260.5 41.845   4 20.922 0.1606 206.0, 301.0 -1.09
BXD90 m 318.0 29.439   4 14.72 0.0926 276.0, 344.0 -0.31
BXD95 m 329.6 58.47   5 26.151 0.1774 261.0, 407.0 -0.15
BXD98 m 438.6 80.25   5 35.887 0.183 331.0, 522.0 1.35
BXD99 m 318.6 45.457   5 20.329 0.1427 245.0, 360.0 -0.3
C57BL/6J m 349.5 40.575   4 20.288 0.1161 304.0, 392.0 0.12
DBA/2J m 256.0 47.508   3 27.429 0.1856 205.0, 299.0 -1.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 306.0 28.4780336576 362.1737239576 249.8262760424
BXD100 m 352.4 28.4780336576 408.5737239576 296.2262760424
BXD101 m 212.5 31.8394095619 275.3041326592 149.6958673408
BXD11 m 241.2 28.4780336576 297.3737239576 185.0262760424
BXD12 m 377.6 28.4780336576 433.7737239576 321.4262760424
BXD16 m 426.0 28.4780336576 482.1737239576 369.8262760424
BXD2 m 268.6 28.4780336576 324.7737239576 212.4262760424
BXD27 m 387.25 31.8394095619 450.0541326592 324.4458673408
BXD32 m 298.3333333333 36.7649833629 370.8532991274 225.8133675393
BXD34 m 338.2 28.4780336576 394.3737239576 282.0262760424
BXD39 m 510.4 28.4780336576 566.5737239576 454.2262760424
BXD40 m 322.75 31.8394095619 385.5541326592 259.9458673408
BXD43 m 344.6666666667 36.7649833629 417.1866324607 272.1467008726
BXD44 m 488.5714285714 24.068331312 536.0468903781 441.0959667647
BXD45 m 277.5 31.8394095619 340.3041326592 214.6958673408
BXD48 m 389.5 31.8394095619 452.3041326592 326.6958673408
BXD48a m 417.6666666667 36.7649833629 490.1866324607 345.1467008726
BXD49 m 267.0 31.8394095619 329.8041326592 204.1958673408
BXD50 m 327.8 28.4780336576 383.9737239576 271.6262760424
BXD51 m 313.0 31.8394095619 375.8041326592 250.1958673408
BXD53 m 423.0 28.4780336576 479.1737239576 366.8262760424
BXD55 m 199.5 31.8394095619 262.3041326592 136.6958673408
BXD56 m 311.25 31.8394095619 374.0541326592 248.4458673408
BXD6 m 321.8 28.4780336576 377.9737239576 265.6262760424
BXD60 m 351.2 28.4780336576 407.3737239576 295.0262760424
BXD61 m 250.8 28.4780336576 306.9737239576 194.6262760424
BXD62 m 315.0 31.8394095619 377.8041326592 252.1958673408
BXD63 m 439.75 31.8394095619 502.5541326592 376.9458673408
BXD64 m 358.25 31.8394095619 421.0541326592 295.4458673408
BXD65 m 379.75 31.8394095619 442.5541326592 316.9458673408
BXD65a m 326.5 31.8394095619 389.3041326592 263.6958673408
BXD66 m 243.25 31.8394095619 306.0541326592 180.4458673408
BXD67 m 363.4 28.4780336576 419.5737239576 307.2262760424
BXD68 m 406.75 31.8394095619 469.5541326592 343.9458673408
BXD69 m 465.4 28.4780336576 521.5737239576 409.2262760424
BXD70 m 333.5 31.8394095619 396.3041326592 270.6958673408
BXD71 m 472.0 36.7649833629 544.519965794 399.480034206
BXD73 m 299.8 28.4780336576 355.9737239576 243.6262760424
BXD73a m 244.0 31.8394095619 306.8041326592 181.1958673408
BXD73b m 240.6 28.4780336576 296.7737239576 184.4262760424
BXD75 m 294.6 28.4780336576 350.7737239576 238.4262760424
BXD77 m 375.6 28.4780336576 431.7737239576 319.4262760424
BXD79 m 275.8 28.4780336576 331.9737239576 219.6262760424
BXD8 m 276.2 28.4780336576 332.3737239576 220.0262760424
BXD81 m 433.25 31.8394095619 496.0541326592 370.4458673408
BXD83 m 340.25 31.8394095619 403.0541326592 277.4458673408
BXD84 m 357.6666666667 36.7649833629 430.1866324607 285.1467008726
BXD85 m 466.5 31.8394095619 529.3041326592 403.6958673408
BXD87 m 359.0 28.4780336576 415.1737239576 302.8262760424
BXD89 m 260.5 31.8394095619 323.3041326592 197.6958673408
BXD90 m 318.0 31.8394095619 380.8041326592 255.1958673408
BXD95 m 329.6 28.4780336576 385.7737239576 273.4262760424
BXD98 m 438.6 28.4780336576 494.7737239576 382.4262760424
BXD99 m 318.6 28.4780336576 374.7737239576 262.4262760424
C57BL/6J m 349.5 31.8394095619 412.3041326592 286.6958673408
DBA/2J m 256.0 36.7649833629 328.519965794 183.480034206




  GWAS USING LINEAR MIXED MODELS