Project measure / variable:   Auwerx1   ogtt_gluc_t15_CD

ID, description, units MPD:111246   ogtt_gluc_t15_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min   [mg/dL]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means286.9   mg/dL
Median of the strain means283.8   mg/dL
SD of the strain means± 63.95
Coefficient of variation (CV)0.2229
Min–max range of strain means163.6   –   488.4   mg/dL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 1082362.1922 19327.8963 6.8059 < 0.0001
Residuals 198 562294.3333 2839.8704


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 241.8 35.436   5 15.847 0.1466 187.0, 282.0 -0.71
BXD100 m 362.0 102.1   3 58.94 0.282 248.0, 445.0 1.17
BXD101 m 310.0 19.916   4 9.9582 0.0642 282.0, 328.0 0.36
BXD11 m 239.8 69.27   4 34.635 0.2889 141.0, 303.0 -0.74
BXD12 m 209.0 23.195   5 10.373 0.111 178.0, 234.0 -1.22
BXD16 m 334.2 68.27   4 34.135 0.2043 233.0, 381.0 0.74
BXD2 m 235.8 39.135   4 19.568 0.166 201.0, 284.0 -0.8
BXD27 m 381.6 53.56   5 23.953 0.1404 329.0, 471.0 1.48
BXD32 m 274.0 22.506   5 10.065 0.0821 236.0, 290.0 -0.2
BXD34 m 388.5 60.32   4 30.162 0.1553 315.0, 445.0 1.59
BXD39 m 408.4 61.26   5 27.398 0.15 339.0, 468.0 1.9
BXD40 m 314.2 74.32   4 37.16 0.2365 209.0, 379.0 0.43
BXD43 m 367.2 35.349   4 17.675 0.0963 339.0, 415.0 1.26
BXD44 m 373.0 77.34   9 25.781 0.2074 303.0, 537.0 1.35
BXD45 m 320.0 24.617   4 12.309 0.0769 288.0, 348.0 0.52
BXD48 m 316.8 41.048   4 20.524 0.1296 264.0, 364.0 0.47
BXD48a m 326.8 67.3   5 30.097 0.2059 275.0, 441.0 0.62
BXD49 m 311.0 31.059   4 15.53 0.0999 284.0, 355.0 0.38
BXD50 m 258.0 49.403   4 24.702 0.1915 188.0, 297.0 -0.45
BXD51 m 215.8 48.781   4 24.39 0.2261 165.0, 259.0 -1.11
BXD53 m 339.2 85.68   5 38.319 0.2526 224.0, 463.0 0.82
BXD55 m 183.4 31.895   5 14.264 0.1739 128.0, 206.0 -1.62
BXD56 m 267.4 77.69   5 34.746 0.2906 193.0, 355.0 -0.3
BXD6 m 277.8 66.68   5 29.822 0.24 181.0, 361.0 -0.14
BXD60 m 210.6 75.37   5 33.708 0.3579 87.0, 278.0 -1.19
BXD61 m 207.3 28.449   3 16.425 0.1372 188.0, 240.0 -1.24
BXD62 m 272.0 29.178   4 14.589 0.1073 237.0, 298.0 -0.23
BXD63 m 344.0 55.52   5 24.831 0.1614 281.0, 405.0 0.89
BXD64 m 245.5 67.77   4 33.886 0.2761 154.0, 310.0 -0.65
BXD65 m 302.5 71.43   4 35.713 0.2361 199.0, 356.0 0.24
BXD65a m 343.2 95.97   5 42.92 0.2796 260.0, 493.0 0.88
BXD65b m 292.0 30.681   4 15.341 0.1051 254.0, 324.0 0.08
BXD66 m 234.2 34.587   4 17.293 0.1476 197.0, 280.0 -0.82
BXD67 m 290.8 32.136   5 14.371 0.1105 235.0, 318.0 0.06
BXD68 m 389.4 28.623   5 12.801 0.0735 371.0, 440.0 1.6
BXD69 m 488.4 98.11   5 43.878 0.2009 339.0, 600.0 3.15
BXD70 m 225.0 65.82   4 32.909 0.2925 142.0, 300.0 -0.97
BXD71 m 289.8 32.725   4 16.362 0.1129 259.0, 336.0 0.05
BXD73 m 217.2 39.127   4 19.563 0.1801 181.0, 269.0 -1.09
BXD73a m 283.8 41.995   4 20.998 0.148 240.0, 335.0 -0.05
BXD73b m 298.0 40.54   5 18.13 0.136 252.0, 356.0 0.17
BXD75 m 240.0 22.483   5 10.055 0.0937 217.0, 276.0 -0.73
BXD77 m 312.6 24.765   5 11.075 0.0792 278.0, 335.0 0.4
BXD79 m 163.6 28.219   5 12.62 0.1725 128.0, 201.0 -1.93
BXD8 m 261.5 19.468   4 9.734 0.0744 243.0, 288.0 -0.4
BXD81 m 295.0 22.583   4 11.292 0.0766 266.0, 317.0 0.13
BXD83 m 229.3 23.861   3 13.776 0.104 210.0, 256.0 -0.9
BXD84 m 221.2 12.95   5 5.7914 0.0585 208.0, 240.0 -1.03
BXD85 m 363.4 68.25   5 30.523 0.1878 289.0, 468.0 1.2
BXD87 m 267.8 48.654   5 21.759 0.1817 210.0, 344.0 -0.3
BXD89 m 268.5 9.7125   4 4.8563 0.0362 254.0, 274.0 -0.29
BXD90 m 252.0 20.865   4 10.432 0.0828 233.0, 272.0 -0.55
BXD95 m 269.8 43.866   4 21.933 0.1626 244.0, 335.0 -0.27
BXD98 m 324.2 54.57   5 24.404 0.1683 263.0, 411.0 0.58
BXD99 m 214.2 41.99   5 18.779 0.196 181.0, 285.0 -1.14
C57BL/6J m 294.5 58.27   4 29.133 0.1978 235.0, 371.0 0.12
DBA/2J m 186.0 51.3   4 25.652 0.2758 126.0, 242.0 -1.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 241.8 23.8322066556 288.7975280602 194.8024719398
BXD100 m 362.0 30.7672464935 422.67354783 301.32645217
BXD101 m 310.0 26.6452170678 362.5448337585 257.4551662415
BXD11 m 239.75 26.6452170678 292.2948337585 187.2051662415
BXD12 m 209.0 23.8322066556 255.9975280602 162.0024719398
BXD16 m 334.25 26.6452170678 386.7948337585 281.7051662415
BXD2 m 235.75 26.6452170678 288.2948337585 183.2051662415
BXD27 m 381.6 23.8322066556 428.5975280602 334.6024719398
BXD32 m 274.0 23.8322066556 320.9975280602 227.0024719398
BXD34 m 388.5 26.6452170678 441.0448337585 335.9551662415
BXD39 m 408.4 23.8322066556 455.3975280602 361.4024719398
BXD40 m 314.25 26.6452170678 366.7948337585 261.7051662415
BXD43 m 367.25 26.6452170678 419.7948337585 314.7051662415
BXD44 m 373.0 17.7634780452 408.0298891724 337.9701108276
BXD45 m 320.0 26.6452170678 372.5448337585 267.4551662415
BXD48 m 316.75 26.6452170678 369.2948337585 264.2051662415
BXD48a m 326.8 23.8322066556 373.7975280602 279.8024719398
BXD49 m 311.0 26.6452170678 363.5448337585 258.4551662415
BXD50 m 258.0 26.6452170678 310.5448337585 205.4551662415
BXD51 m 215.75 26.6452170678 268.2948337585 163.2051662415
BXD53 m 339.2 23.8322066556 386.1975280602 292.2024719398
BXD55 m 183.4 23.8322066556 230.3975280602 136.4024719398
BXD56 m 267.4 23.8322066556 314.3975280602 220.4024719398
BXD6 m 277.8 23.8322066556 324.7975280602 230.8024719398
BXD60 m 210.6 23.8322066556 257.5975280602 163.6024719398
BXD61 m 207.3333333333 30.7672464935 268.0068811634 146.6597855033
BXD62 m 272.0 26.6452170678 324.5448337585 219.4551662415
BXD63 m 344.0 23.8322066556 390.9975280602 297.0024719398
BXD64 m 245.5 26.6452170678 298.0448337585 192.9551662415
BXD65 m 302.5 26.6452170678 355.0448337585 249.9551662415
BXD65a m 343.2 23.8322066556 390.1975280602 296.2024719398
BXD65b m 292.0 26.6452170678 344.5448337585 239.4551662415
BXD66 m 234.25 26.6452170678 286.7948337585 181.7051662415
BXD67 m 290.8 23.8322066556 337.7975280602 243.8024719398
BXD68 m 389.4 23.8322066556 436.3975280602 342.4024719398
BXD69 m 488.4 23.8322066556 535.3975280602 441.4024719398
BXD70 m 225.0 26.6452170678 277.5448337585 172.4551662415
BXD71 m 289.75 26.6452170678 342.2948337585 237.2051662415
BXD73 m 217.25 26.6452170678 269.7948337585 164.7051662415
BXD73a m 283.75 26.6452170678 336.2948337585 231.2051662415
BXD73b m 298.0 23.8322066556 344.9975280602 251.0024719398
BXD75 m 240.0 23.8322066556 286.9975280602 193.0024719398
BXD77 m 312.6 23.8322066556 359.5975280602 265.6024719398
BXD79 m 163.6 23.8322066556 210.5975280602 116.6024719398
BXD8 m 261.5 26.6452170678 314.0448337585 208.9551662415
BXD81 m 295.0 26.6452170678 347.5448337585 242.4551662415
BXD83 m 229.3333333333 30.7672464935 290.0068811634 168.6597855033
BXD84 m 221.2 23.8322066556 268.1975280602 174.2024719398
BXD85 m 363.4 23.8322066556 410.3975280602 316.4024719398
BXD87 m 267.8 23.8322066556 314.7975280602 220.8024719398
BXD89 m 268.5 26.6452170678 321.0448337585 215.9551662415
BXD90 m 252.0 26.6452170678 304.5448337585 199.4551662415
BXD95 m 269.75 26.6452170678 322.2948337585 217.2051662415
BXD98 m 324.2 23.8322066556 371.1975280602 277.2024719398
BXD99 m 214.2 23.8322066556 261.1975280602 167.2024719398
C57BL/6J m 294.5 26.6452170678 347.0448337585 241.9551662415
DBA/2J m 186.0 26.6452170678 238.5448337585 133.4551662415




  GWAS USING LINEAR MIXED MODELS