Project measure / variable:   Auwerx1   ogtt_gluc_t0_HFD

ID, description, units MPD:111245   ogtt_gluc_t0_HFD   glucose baseline, glucose tolerance test (pregavage, overnight fast)   [mg/dL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose baseline, glucose tolerance test (pregavage, overnight fast) HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means143.0   mg/dL
Median of the strain means144.8   mg/dL
SD of the strain means± 36.585
Coefficient of variation (CV)0.2559
Min–max range of strain means76.2   –   243.9   mg/dL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 376023.086 6836.7834 13.8001 < 0.0001
Residuals 195 96606.3264 495.4171


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 93.2 18.102   5 8.0957 0.1942 69.0, 120.0 -1.36
BXD100 m 163.0 30.216   5 13.513 0.1854 122.0, 203.0 0.55
BXD101 m 93.75 17.095   4 8.5477 0.1824 78.0, 115.0 -1.35
BXD11 m 78.2 8.4676   5 3.7868 0.1083 68.0, 85.0 -1.77
BXD12 m 99.2 14.412   5 6.4452 0.1453 87.0, 124.0 -1.2
BXD16 m 148.4 11.127   5 4.9759 0.075 134.0, 163.0 0.15
BXD2 m 146.6 20.84   5 9.3199 0.1422 121.0, 178.0 0.1
BXD27 m 175.9 36.602   4 18.301 0.2081 139.0, 226.5 0.9
BXD32 m 130.8 24.391   4 12.195 0.1865 111.0, 166.0 -0.33
BXD34 m 103.8 11.777   5 5.2669 0.1135 89.0, 121.0 -1.07
BXD39 m 206.4 19.629   5 8.7784 0.0951 183.0, 229.0 1.73
BXD40 m 100.2 6.2915   4 3.1458 0.0628 91.0, 105.0 -1.17
BXD43 m 89.33 7.0238   3 4.0552 0.0786 82.0, 96.0 -1.47
BXD44 m 243.9 32.351   9 10.784 0.1326 203.0, 288.0 2.76
BXD45 m 163.2 13.817   4 6.9086 0.0846 147.0, 179.0 0.55
BXD48 m 145.2 47.864   4 23.932 0.3295 90.0, 191.0 0.06
BXD48a m 159.3 6.5064   3 3.7565 0.0408 153.0, 166.0 0.45
BXD49 m 113.2 16.153   4 8.0765 0.1426 98.0, 136.0 -0.81
BXD50 m 144.2 16.423   5 7.3444 0.1139 122.0, 161.0 0.03
BXD51 m 178.2 21.407   4 10.703 0.1201 161.0, 209.0 0.96
BXD53 m 166.8 30.045   5 13.437 0.1801 129.0, 208.0 0.65
BXD55 m 76.2 3.2711   5 1.4629 0.0429 71.0, 80.0 -1.83
BXD56 m 118.8 20.255   4 10.127 0.1706 100.0, 145.0 -0.66
BXD6 m 116.0 23.345   5 10.44 0.2013 77.0, 139.0 -0.74
BXD60 m 190.4 32.777   5 14.658 0.1721 141.0, 222.0 1.3
BXD61 m 144.4 8.5615   5 3.8288 0.0593 134.0, 154.0 0.04
BXD62 m 131.8 14.5   4 7.25 0.1101 113.0, 147.0 -0.31
BXD63 m 198.2 16.681   4 8.3404 0.0841 179.0, 215.0 1.51
BXD64 m 138.0 16.166   4 8.0829 0.1171 124.0, 160.0 -0.14
BXD65 m 198.5 12.897   4 6.4485 0.065 183.0, 211.0 1.52
BXD65a m 149.2 15.064   4 7.5319 0.1009 129.0, 165.0 0.17
BXD66 m 146.5 6.1373   4 3.0687 0.0419 141.0, 154.0 0.1
BXD67 m 162.0 19.013   5 8.5029 0.1174 135.0, 180.0 0.52
BXD68 m 78.5 19.824   4 9.9121 0.2525 56.0, 104.0 -1.76
BXD69 m 201.8 51.51   5 23.036 0.2552 133.0, 265.0 1.61
BXD70 m 122.0 17.378   4 8.6891 0.1424 103.0, 140.0 -0.57
BXD71 m 160.8 37.411   4 18.706 0.2327 111.0, 200.0 0.49
BXD73 m 125.8 24.813   5 11.097 0.1972 104.0, 167.0 -0.47
BXD73a m 162.0 8.8318   4 4.4159 0.0545 150.0, 171.0 0.52
BXD73b m 101.8 17.838   5 7.9775 0.1752 77.0, 122.0 -1.13
BXD75 m 163.4 14.536   5 6.5008 0.089 150.0, 188.0 0.56
BXD77 m 179.6 29.518   5 13.201 0.1644 137.0, 207.0 1.0
BXD79 m 133.4 4.0988   5 1.833 0.0307 129.0, 137.0 -0.26
BXD8 m 111.4 15.694   5 7.0185 0.1409 95.0, 137.0 -0.86
BXD81 m 158.5 23.231   4 11.615 0.1466 135.0, 187.0 0.42
BXD83 m 185.5 30.161   4 15.08 0.1626 163.0, 230.0 1.16
BXD84 m 135.0 27.514   3 15.885 0.2038 108.0, 163.0 -0.22
BXD85 m 134.8 29.658   4 14.829 0.2201 102.0, 169.0 -0.22
BXD87 m 191.0 13.601   5 6.0828 0.0712 168.0, 202.0 1.31
BXD89 m 95.25 16.939   4 8.4693 0.1778 75.0, 115.0 -1.3
BXD90 m 156.8 13.769   4 6.8845 0.0878 145.0, 176.0 0.38
BXD95 m 131.6 28.553   5 12.769 0.217 88.0, 157.0 -0.31
BXD98 m 158.2 15.595   5 6.9742 0.0986 133.0, 172.0 0.42
BXD99 m 111.6 21.478   5 9.6052 0.1925 94.0, 148.0 -0.86
C57BL/6J m 163.0 12.193   4 6.0964 0.0748 151.0, 180.0 0.55
DBA/2J m 132.7 6.0277   3 3.4801 0.0454 127.0, 139.0 -0.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 93.2 9.9540650832 112.8314474837 73.5685525163
BXD100 m 163.0 9.9540650832 182.6314474837 143.3685525163
BXD101 m 93.75 11.1289830893 115.6986255351 71.8013744649
BXD11 m 78.2 9.9540650832 97.8314474837 58.5685525163
BXD12 m 99.2 9.9540650832 118.8314474837 79.5685525163
BXD16 m 148.4 9.9540650832 168.0314474837 128.7685525163
BXD2 m 146.6 9.9540650832 166.2314474837 126.9685525163
BXD27 m 175.875 11.1289830893 197.8236255351 153.9263744649
BXD32 m 130.75 11.1289830893 152.6986255351 108.8013744649
BXD34 m 103.8 9.9540650832 123.4314474837 84.1685525163
BXD39 m 206.4 9.9540650832 226.0314474837 186.7685525163
BXD40 m 100.25 11.1289830893 122.1986255351 78.3013744649
BXD43 m 89.3333333333 12.8506427648 114.6774230555 63.9892436112
BXD44 m 243.8888888889 7.4193220595 258.5213059123 229.2564718655
BXD45 m 163.25 11.1289830893 185.1986255351 141.3013744649
BXD48 m 145.25 11.1289830893 167.1986255351 123.3013744649
BXD48a m 159.3333333333 12.8506427648 184.6774230555 133.9892436112
BXD49 m 113.25 11.1289830893 135.1986255351 91.3013744649
BXD50 m 144.2 9.9540650832 163.8314474837 124.5685525163
BXD51 m 178.25 11.1289830893 200.1986255351 156.3013744649
BXD53 m 166.8 9.9540650832 186.4314474837 147.1685525163
BXD55 m 76.2 9.9540650832 95.8314474837 56.5685525163
BXD56 m 118.75 11.1289830893 140.6986255351 96.8013744649
BXD6 m 116.0 9.9540650832 135.6314474837 96.3685525163
BXD60 m 190.4 9.9540650832 210.0314474837 170.7685525163
BXD61 m 144.4 9.9540650832 164.0314474837 124.7685525163
BXD62 m 131.75 11.1289830893 153.6986255351 109.8013744649
BXD63 m 198.25 11.1289830893 220.1986255351 176.3013744649
BXD64 m 138.0 11.1289830893 159.9486255351 116.0513744649
BXD65 m 198.5 11.1289830893 220.4486255351 176.5513744649
BXD65a m 149.25 11.1289830893 171.1986255351 127.3013744649
BXD66 m 146.5 11.1289830893 168.4486255351 124.5513744649
BXD67 m 162.0 9.9540650832 181.6314474837 142.3685525163
BXD68 m 78.5 11.1289830893 100.4486255351 56.5513744649
BXD69 m 201.8 9.9540650832 221.4314474837 182.1685525163
BXD70 m 122.0 11.1289830893 143.9486255351 100.0513744649
BXD71 m 160.75 11.1289830893 182.6986255351 138.8013744649
BXD73 m 125.8 9.9540650832 145.4314474837 106.1685525163
BXD73a m 162.0 11.1289830893 183.9486255351 140.0513744649
BXD73b m 101.8 9.9540650832 121.4314474837 82.1685525163
BXD75 m 163.4 9.9540650832 183.0314474837 143.7685525163
BXD77 m 179.6 9.9540650832 199.2314474837 159.9685525163
BXD79 m 133.4 9.9540650832 153.0314474837 113.7685525163
BXD8 m 111.4 9.9540650832 131.0314474837 91.7685525163
BXD81 m 158.5 11.1289830893 180.4486255351 136.5513744649
BXD83 m 185.5 11.1289830893 207.4486255351 163.5513744649
BXD84 m 135.0 12.8506427648 160.3440897221 109.6559102779
BXD85 m 134.75 11.1289830893 156.6986255351 112.8013744649
BXD87 m 191.0 9.9540650832 210.6314474837 171.3685525163
BXD89 m 95.25 11.1289830893 117.1986255351 73.3013744649
BXD90 m 156.75 11.1289830893 178.6986255351 134.8013744649
BXD95 m 131.6 9.9540650832 151.2314474837 111.9685525163
BXD98 m 158.2 9.9540650832 177.8314474837 138.5685525163
BXD99 m 111.6 9.9540650832 131.2314474837 91.9685525163
C57BL/6J m 163.0 11.1289830893 184.9486255351 141.0513744649
DBA/2J m 132.6666666667 12.8506427648 158.0107563888 107.3225769445




  GWAS USING LINEAR MIXED MODELS