Project measure / variable:   CSNA03   total_time_in_acq_JAX

ID, description, units MPD:110469   total_time_in_acq_JAX   total time for all trials (reversal learning assay), founders   [min]  acquisition  
Data set, strains CSNA03   inbred w/CC8   8 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - total time for all trials (reversal learning assay), founders acquisition



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means239.2   min 176.4   min
Median of the strain means131.2   min 130.6   min
SD of the strain means± 242.7 ± 157.7
Coefficient of variation (CV)1.0148 0.8939
Min–max range of strain means62.79   –   763.2   min 19.165   –   530.9   min
Mean sample size per strain7.6   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8406.8588 8406.8588 0.3808 0.5386
strain 7 1876930.376 268132.9109 12.1469 < 0.0001
sex:strain 7 686443.7141 98063.3877 4.4424 0.0002
Residuals 100 2207421.9308 22074.2193


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 763.2 331.8   3 191.5 0.4347 385.6, 1008.0 2.16
129S1/SvImJ m 207.0 250.0   4 125.0 1.2079 24.352, 558.8 0.19
A/J f 442.0 211.8   6 86.46 0.4791 32.177, 596.8 0.84
A/J m 530.9 236.9   5 105.9 0.4462 292.9, 819.9 2.25
C57BL/6J f 150.9 93.61   14 25.017 0.6202 13.457, 325.1 -0.36
C57BL/6J m 85.03 58.29   11 17.575 0.6855 7.768, 219.2 -0.58
CAST/EiJ f 111.4 78.75   10 24.903 0.7066 20.858, 264.3 -0.53
CAST/EiJ m 221.1 209.6   8 74.09 0.9477 18.327, 539.2 0.28
NOD/ShiLtJ f 93.68 127.1   8 44.946 1.357 13.723, 397.8 -0.6
NOD/ShiLtJ m 124.8 125.0   11 37.7 1.0017 13.477, 412.8 -0.33
NZO/HlLtJ f 109.4 138.5   3 79.98 1.2663 26.16, 269.3 -0.53
NZO/HlLtJ m 19.165 6.5082   2   4.602 0.3396 14.563, 23.767 -1.0
PWK/PhJ f 62.79 49.659   9 16.553 0.7909 15.485, 165.2 -0.73
PWK/PhJ m 136.3 169.4   8 59.88 1.2429 15.848, 524.9 -0.25
WSB/EiJ f 180.2 204.4   8 72.25 1.1341 35.002, 630.2 -0.24
WSB/EiJ m 86.71 61.88   6 25.262 0.7136 32.182, 165.9 -0.57


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 763.2 85.7792113667 933.383512233 593.016487767
129S1/SvImJ m 206.99975 74.2869761602 354.382994899 59.616505101
A/J f 442.0128333333 60.6550620422 562.3507488794 321.6749177872
A/J m 530.88 66.4442914148 662.7035817355 399.0564182645
C57BL/6J f 150.9221428571 39.708059013 229.7018009947 72.1424847195
C57BL/6J m 85.0340909091 44.7967321333 173.9095315846 -3.8413497664
CAST/EiJ f 111.4441 46.9832090306 204.6574485655 18.2307514345
CAST/EiJ m 221.13025 52.5288245967 325.3459419014 116.9145580986
NOD/ShiLtJ f 93.6805 52.5288245967 197.8961919014 -10.5351919014
NOD/ShiLtJ m 124.8304545455 44.7967321333 213.7058952209 35.95501387
NZO/HlLtJ f 109.3943333333 85.7792113667 279.5778455663 -60.7891788997
NZO/HlLtJ m 19.165 105.0576491934 227.5963838028 -189.2663838028
PWK/PhJ f 62.7886666667 49.5246507735 161.044163266 -35.4668299327
PWK/PhJ m 136.270375 52.5288245967 240.4860669014 32.0546830986
WSB/EiJ f 180.1915 52.5288245967 284.4071919014 75.9758080986
WSB/EiJ m 86.7106666667 60.6550620422 207.0485822128 -33.6272488794


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 485.099875 56.7376152339 597.665687653 372.534062347
A/J both 486.4464166667 44.9829979352 575.691403388 397.2014299453
C57BL/6J both 117.9781168831 29.9310756589 177.3605185092 58.595715257
CAST/EiJ both 166.287175 35.2374067729 236.1971864241 96.3771635759
NOD/ShiLtJ both 109.2554772727 34.5182003563 177.7386036502 40.7723508952
NZO/HlLtJ both 64.2796666667 67.814420953 198.8215463825 -70.2622130492
PWK/PhJ both 99.5295208333 36.0969820336 171.1449050927 27.914136574
WSB/EiJ both 133.4510833333 40.1195524802 213.04713279 53.8550338766




  GWAS USING LINEAR MIXED MODELS