Phenotype measure:   Wahlsten1   cc_index

ID, description, units MPD:10812   cc_index   corpus callosum index (0=absent, 1=normal, <0.65 is abnormal)   [score]
Data set, strains Wahlsten1   inbred   21 strains     sex: both     age: 12wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Wahlsten1 - corpus callosum index (0=absent, 1=normal, <0.65 is abnormal)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains20 strains
Mean of the strain means0.931   score 0.934   score
Median of the strain means1.00   score 0.980   score
SD of the strain means± 0.251 ± 0.247
Coefficient of variation (CV)0.269 0.265
Min–max range of strain means0   –   1.15   score 0.00185   –   1.16   score
Mean sample size per strain9.5   mice 9.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0286 0.0286 1.3818 0.2406
strain 19 21.9028 1.1528 55.6921 < 0.0001
sex:strain 19 0.3948 0.0208 1.0039 0.4556
Residuals 345 7.1412 0.0207


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.623 0.472   10 0.149 0.758 -1.23
129S1/SvImJ m 0.813 0.433   10 0.137 0.532 -0.49
A/J f 0.991 0.0615   8 0.0217 0.0621 0.904, 1.08 0.24
A/J m 0.97 0.0384   10 0.0121 0.0396 0.908, 1.02 0.15
AKR/J f 0.96 0.0364   9 0.0121 0.0379 0.883, 1.0 0.11
AKR/J m 0.993 0.0825   8 0.0292 0.0831 0.872, 1.15 0.24
BALB/cByJ f 1.05 0.176   10 0.0558 0.169 0.601, 1.24 0.47
BALB/cByJ m 0.913 0.384   10 0.121 0.421 -0.08
BTBR T+ Itpr3tf/J f 0.0 0.0   12 0.0 0.0 -3.72
BTBR T+ Itpr3tf/J m 0.00185 0.00453   6 0.00185 2.45 -3.77
C3H/HeJ f 1.05 0.109   10 0.0344 0.103 0.791, 1.17 0.47
C3H/HeJ m 0.928 0.0888   8 0.0314 0.0956 0.796, 1.02 -0.02
C57BL/6J f 1.07 0.0463   8 0.0164 0.0431 1.0, 1.12 0.55
C57BL/6J m 1.07 0.104   10 0.0328 0.0968 0.976, 1.3 0.55
C57L/J f 1.11 0.109   10 0.0345 0.0985 0.936, 1.28 0.71
C57L/J m 1.12 0.0599   8 0.0212 0.0534 1.01, 1.22 0.75
C58/J f 1.11 0.0695   9 0.0232 0.0626 1.04, 1.26 0.71
C58/J m 1.16 0.138   10 0.0435 0.118 0.994, 1.43 0.92
CAST/EiJ f 1.0 0.0546   9 0.0182 0.0545 0.904, 1.1 0.27
CAST/EiJ m 0.996 0.116   9 0.0387 0.117 0.805, 1.14 0.25
DBA/2J f 0.89 0.0516   10 0.0163 0.058 0.769, 0.965 -0.16
DBA/2J m 0.877 0.096   8 0.0339 0.109 0.716, 1.03 -0.23
FVB/NJ f 1.11 0.0769   10 0.0243 0.0691 0.993, 1.22 0.71
FVB/NJ m 1.13 0.0396   11 0.0119 0.0352 1.05, 1.18 0.79
MOLF/EiJ f 0.943 0.0698   8 0.0247 0.074 0.829, 1.03 0.05
MOLF/EiJ m 0.991 0.0698   6 0.0285 0.0704 0.899, 1.1 0.23
NOD/ShiLtJ f 1.02 0.0286   12 0.00826 0.0279 0.986, 1.06 0.35
NOD/ShiLtJ m 0.998 0.078   12 0.0225 0.0781 0.83, 1.1 0.26
NZB/BlNJ f 0.706 0.0444   6 0.0181 0.063 0.655, 0.788 -0.9
NZB/BlNJ m 0.709 0.0849   12 0.0245 0.12 0.608, 0.867 -0.91
PERA/EiJ f 0.891 0.0623   10 0.0197 0.07 0.827, 1.0 -0.16
PERA/EiJ m 0.893 0.0435   12 0.0126 0.0487 0.845, 1.0 -0.16
PL/J f 0.946 0.0451   12 0.013 0.0476 0.872, 1.0 0.06
PL/J m 0.956 0.0361   8 0.0128 0.0378 0.908, 1.02 0.09
SJL/J f 1.01 0.0686   8 0.0243 0.0678 0.927, 1.12 0.31
SJL/J m 0.952 0.105   12 0.0304 0.111 0.683, 1.07 0.07
SM/J f 1.15 0.148   14 0.0394 0.129 0.698, 1.34 0.87
SM/J m 1.16 0.0637   10 0.0202 0.055 1.07, 1.24 0.92
SPRET/EiJ f 0.857 0.0622   5 0.0278 0.0726 0.771, 0.94 -0.3
SWR/J f 1.07 0.0495   10 0.0156 0.0464 1.01, 1.16 0.55
SWR/J m 1.04 0.0587   10 0.0186 0.0563 0.945, 1.11 0.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6227 0.0455 0.7122 0.5332
129S1/SvImJ m 0.8133 0.0455 0.9028 0.7238
A/J f 0.9909 0.0509 1.0909 0.8908
A/J m 0.9702 0.0455 1.0597 0.8807
AKR/J f 0.9599 0.048 1.0542 0.8656
AKR/J m 0.9928 0.0509 1.0928 0.8927
BALB/cByJ f 1.0471 0.0455 1.1366 0.9576
BALB/cByJ m 0.9131 0.0455 1.0026 0.8236
BTBR T+ Itpr3tf/J f 0.0 0.0415 0.0817 -0.0817
BTBR T+ Itpr3tf/J m 0.0019 0.0587 0.1174 -0.1137
C3H/HeJ f 1.052 0.0455 1.1415 0.9625
C3H/HeJ m 0.9285 0.0509 1.0285 0.8285
C57BL/6J f 1.0738 0.0509 1.1738 0.9737
C57BL/6J m 1.0719 0.0455 1.1614 0.9824
C57L/J f 1.1074 0.0455 1.1969 1.0179
C57L/J m 1.1225 0.0509 1.2225 1.0225
C58/J f 1.11 0.048 1.2043 1.0157
C58/J m 1.1624 0.0455 1.2519 1.0729
CAST/EiJ f 1.0029 0.048 1.0972 0.9086
CAST/EiJ m 0.9958 0.048 1.0901 0.9015
DBA/2J f 0.8896 0.0455 0.9791 0.8001
DBA/2J m 0.8766 0.0509 0.9767 0.7766
FVB/NJ f 1.1133 0.0455 1.2028 1.0238
FVB/NJ m 1.1255 0.0434 1.2108 1.0401
MOLF/EiJ f 0.9425 0.0509 1.0425 0.8425
MOLF/EiJ m 0.9915 0.0587 1.107 0.876
NOD/ShiLtJ f 1.0243 0.0415 1.106 0.9426
NOD/ShiLtJ m 0.9982 0.0415 1.0799 0.9165
NZB/BlNJ f 0.7055 0.0587 0.821 0.59
NZB/BlNJ m 0.7092 0.0415 0.7909 0.6275
PERA/EiJ f 0.8907 0.0455 0.9802 0.8012
PERA/EiJ m 0.8928 0.0415 0.9745 0.8111
PL/J f 0.9458 0.0415 1.0274 0.8641
PL/J m 0.9561 0.0509 1.0562 0.8561
SJL/J f 1.0128 0.0509 1.1128 0.9127
SJL/J m 0.9524 0.0415 1.0341 0.8707
SM/J f 1.1477 0.0385 1.2233 1.0721
SM/J m 1.158 0.0455 1.2475 1.0685
SWR/J f 1.066 0.0455 1.1555 0.9765
SWR/J m 1.0428 0.0455 1.1323 0.9533


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.718 0.0322 0.7813 0.6547
A/J both 0.9805 0.0341 1.0477 0.9134
AKR/J both 0.9763 0.035 1.0451 0.9076
BALB/cByJ both 0.9801 0.0322 1.0434 0.9168
BTBR T+ Itpr3tf/J both 0.0009 0.036 0.0717 -0.0698
C3H/HeJ both 0.9902 0.0341 1.0574 0.9231
C57BL/6J both 1.0728 0.0341 1.1399 1.0057
C57L/J both 1.115 0.0341 1.1821 1.0478
C58/J both 1.1362 0.0331 1.2012 1.0712
CAST/EiJ both 0.9993 0.0339 1.066 0.9326
DBA/2J both 0.8831 0.0341 0.9502 0.816
FVB/NJ both 1.1194 0.0314 1.1812 1.0576
MOLF/EiJ both 0.967 0.0388 1.0434 0.8906
NOD/ShiLtJ both 1.0113 0.0294 1.069 0.9535
NZB/BlNJ both 0.7073 0.036 0.7781 0.6366
PERA/EiJ both 0.8918 0.0308 0.9523 0.8312
PL/J both 0.9509 0.0328 1.0155 0.8864
SJL/J both 0.9826 0.0328 1.0472 0.918
SM/J both 1.1529 0.0298 1.2114 1.0943
SWR/J both 1.0544 0.0322 1.1177 0.9911




  GWAS USING LINEAR MIXED MODELS