Phenotype measure:   Wahlsten1   hc_area

ID, description, units MPD:10810   hc_area   cross-sectional area of hippocampal commissure at midplane   [mm2]
Data set, strains Wahlsten1   inbred   21 strains     sex: both     age: 12wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Wahlsten1 - cross-sectional area of hippocampal commissure at midplane



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains20 strains
Mean of the strain means0.282   mm2 0.292   mm2
Median of the strain means0.295   mm2 0.301   mm2
SD of the strain means± 0.0760 ± 0.0667
Coefficient of variation (CV)0.270 0.229
Min–max range of strain means0.0949   –   0.422   mm2 0.169   –   0.410   mm2
Mean sample size per strain9.5   mice 9.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0138 0.0138 12.1836 0.0005
strain 19 1.8876 0.0993 87.8099 < 0.0001
sex:strain 19 0.0414 0.0022 1.9258 0.0117
Residuals 345 0.3903 0.0011


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.295 0.0747   10 0.0236 0.253 0.151, 0.45 0.17
129S1/SvImJ m 0.293 0.0309   10 0.00977 0.105 0.223, 0.339 0.02
A/J f 0.285 0.0311   8 0.011 0.109 0.238, 0.327 0.04
A/J m 0.293 0.0206   10 0.0065 0.0703 0.263, 0.319 0.02
AKR/J f 0.303 0.027   9 0.00899 0.089 0.262, 0.342 0.28
AKR/J m 0.288 0.0331   8 0.0117 0.115 0.235, 0.351 -0.06
BALB/cByJ f 0.293 0.0367   10 0.0116 0.125 0.222, 0.338 0.15
BALB/cByJ m 0.33 0.0393   10 0.0124 0.119 0.282, 0.406 0.57
BTBR T+ Itpr3tf/J f 0.0949 0.0389   12 0.0112 0.41 0.036, 0.146 -2.46
BTBR T+ Itpr3tf/J m 0.171 0.0948   6 0.0387 0.555 0.038, 0.316 -1.81
C3H/HeJ f 0.366 0.0177   10 0.00561 0.0484 0.334, 0.385 1.11
C3H/HeJ m 0.35 0.0301   8 0.0106 0.0859 0.304, 0.4 0.87
C57BL/6J f 0.3 0.0377   8 0.0133 0.126 0.259, 0.372 0.24
C57BL/6J m 0.316 0.0292   10 0.00923 0.0924 0.276, 0.354 0.36
C57L/J f 0.256 0.0182   10 0.00575 0.0712 0.234, 0.29 -0.34
C57L/J m 0.266 0.0221   8 0.00783 0.0833 0.24, 0.314 -0.39
C58/J f 0.282 0.0401   9 0.0134 0.142 0.229, 0.346 0.0
C58/J m 0.278 0.031   10 0.0098 0.111 0.251, 0.359 -0.21
CAST/EiJ f 0.253 0.0267   9 0.0089 0.106 0.215, 0.311 -0.38
CAST/EiJ m 0.257 0.0298   9 0.00992 0.116 0.203, 0.311 -0.52
DBA/2J f 0.224 0.042   10 0.0133 0.188 0.164, 0.302 -0.76
DBA/2J m 0.216 0.0198   8 0.00701 0.0917 0.186, 0.248 -1.14
FVB/NJ f 0.303 0.0183   10 0.0058 0.0605 0.278, 0.336 0.28
FVB/NJ m 0.317 0.0245   11 0.00739 0.0774 0.28, 0.351 0.38
MOLF/EiJ f 0.157 0.0104   8 0.00369 0.0666 0.139, 0.168 -1.64
MOLF/EiJ m 0.169 0.00817   6 0.00333 0.0482 0.157, 0.178 -1.84
NOD/ShiLtJ f 0.422 0.0453   12 0.0131 0.107 0.372, 0.5 1.85
NOD/ShiLtJ m 0.41 0.0259   12 0.00748 0.0633 0.378, 0.457 1.77
NZB/BlNJ f 0.338 0.0179   6 0.00729 0.0528 0.313, 0.363 0.74
NZB/BlNJ m 0.327 0.0397   12 0.0115 0.121 0.262, 0.378 0.53
PERA/EiJ f 0.185 0.0181   10 0.00572 0.0978 0.162, 0.217 -1.27
PERA/EiJ m 0.18 0.0232   12 0.00669 0.129 0.145, 0.215 -1.68
PL/J f 0.322 0.023   12 0.00665 0.0715 0.292, 0.355 0.53
PL/J m 0.343 0.00815   8 0.00288 0.0238 0.334, 0.354 0.76
SJL/J f 0.342 0.0291   8 0.0103 0.0851 0.304, 0.375 0.79
SJL/J m 0.351 0.0368   12 0.0106 0.105 0.275, 0.405 0.88
SM/J f 0.357 0.035   14 0.00935 0.0981 0.284, 0.421 0.99
SM/J m 0.375 0.0281   10 0.0089 0.0751 0.341, 0.426 1.24
SPRET/EiJ f 0.206 0.0227   5 0.0101 0.11 0.173, 0.237 -1.0
SWR/J f 0.333 0.0259   10 0.00819 0.0778 0.284, 0.366 0.67
SWR/J m 0.309 0.0327   10 0.0103 0.106 0.257, 0.359 0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2951 0.0106 0.316 0.2742
129S1/SvImJ m 0.2931 0.0106 0.314 0.2722
A/J f 0.2848 0.0119 0.3081 0.2614
A/J m 0.2925 0.0106 0.3134 0.2716
AKR/J f 0.3032 0.0112 0.3253 0.2812
AKR/J m 0.2876 0.0119 0.311 0.2642
BALB/cByJ f 0.2927 0.0106 0.3136 0.2718
BALB/cByJ m 0.3297 0.0106 0.3506 0.3088
BTBR T+ Itpr3tf/J f 0.0949 0.0097 0.114 0.0758
BTBR T+ Itpr3tf/J m 0.1708 0.0137 0.1978 0.1438
C3H/HeJ f 0.3663 0.0106 0.3872 0.3454
C3H/HeJ m 0.3501 0.0119 0.3735 0.3267
C57BL/6J f 0.2996 0.0119 0.323 0.2762
C57BL/6J m 0.3159 0.0106 0.3368 0.295
C57L/J f 0.2556 0.0106 0.2765 0.2347
C57L/J m 0.266 0.0119 0.2894 0.2426
C58/J f 0.2824 0.0112 0.3045 0.2604
C58/J m 0.2781 0.0106 0.299 0.2572
CAST/EiJ f 0.2527 0.0112 0.2747 0.2306
CAST/EiJ m 0.2567 0.0112 0.2787 0.2346
DBA/2J f 0.224 0.0106 0.2449 0.2031
DBA/2J m 0.2162 0.0119 0.2396 0.1929
FVB/NJ f 0.3034 0.0106 0.3243 0.2825
FVB/NJ m 0.3166 0.0101 0.3366 0.2967
MOLF/EiJ f 0.1566 0.0119 0.18 0.1332
MOLF/EiJ m 0.1695 0.0137 0.1965 0.1425
NOD/ShiLtJ f 0.4218 0.0097 0.4408 0.4027
NOD/ShiLtJ m 0.4096 0.0097 0.4287 0.3905
NZB/BlNJ f 0.3383 0.0137 0.3653 0.3113
NZB/BlNJ m 0.3273 0.0097 0.3463 0.3082
PERA/EiJ f 0.1851 0.0106 0.206 0.1642
PERA/EiJ m 0.18 0.0097 0.1991 0.1609
PL/J f 0.3222 0.0097 0.3413 0.3031
PL/J m 0.3431 0.0119 0.3665 0.3197
SJL/J f 0.3419 0.0119 0.3653 0.3185
SJL/J m 0.3512 0.0097 0.3703 0.3321
SM/J f 0.3566 0.009 0.3743 0.339
SM/J m 0.3748 0.0106 0.3957 0.3539
SWR/J f 0.3327 0.0106 0.3536 0.3118
SWR/J m 0.3091 0.0106 0.33 0.2882


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2941 0.0075 0.3089 0.2793
A/J both 0.2886 0.008 0.3043 0.2729
AKR/J both 0.2954 0.0082 0.3115 0.2794
BALB/cByJ both 0.3112 0.0075 0.326 0.2964
BTBR T+ Itpr3tf/J both 0.1329 0.0084 0.1494 0.1163
C3H/HeJ both 0.3582 0.008 0.3739 0.3425
C57BL/6J both 0.3078 0.008 0.3235 0.2921
C57L/J both 0.2608 0.008 0.2765 0.2451
C58/J both 0.2803 0.0077 0.2955 0.2651
CAST/EiJ both 0.2547 0.0079 0.2703 0.2391
DBA/2J both 0.2201 0.008 0.2358 0.2044
FVB/NJ both 0.31 0.0073 0.3245 0.2956
MOLF/EiJ both 0.1631 0.0091 0.1809 0.1452
NOD/ShiLtJ both 0.4157 0.0069 0.4292 0.4022
NZB/BlNJ both 0.3328 0.0084 0.3493 0.3163
PERA/EiJ both 0.1825 0.0072 0.1967 0.1684
PL/J both 0.3326 0.0077 0.3477 0.3175
SJL/J both 0.3465 0.0077 0.3616 0.3314
SM/J both 0.3657 0.007 0.3794 0.352
SWR/J both 0.3209 0.0075 0.3357 0.3061




  GWAS USING LINEAR MIXED MODELS