Project measure / variable:   Wahlsten1   cc_area

ID, description, units MPD:10809   cc_area   cross-sectional area of corpus callosum at midplane   [mm2]  
Data set, strains Wahlsten1   inbred   21 strains     sex: both     age: 12wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Wahlsten1 - cross-sectional area of corpus callosum at midplane



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains20 strains
Mean of the strain means0.800   mm2 0.810   mm2
Median of the strain means0.892   mm2 0.809   mm2
SD of the strain means± 0.254 ± 0.250
Coefficient of variation (CV)0.317 0.309
Min–max range of strain means0   –   1.16   mm2 0.00167   –   1.11   mm2
Mean sample size per strain9.5   mice 9.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0283 0.0283 1.5634 0.212
strain 19 22.581 1.1885 65.7119 < 0.0001
sex:strain 19 0.3715 0.0196 1.081 0.3687
Residuals 345 6.2397 0.0181


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.582 0.429   10 0.136 0.737 -0.86
129S1/SvImJ m 0.763 0.416   10 0.131 0.545 -0.19
A/J f 0.755 0.0603   8 0.0213 0.0798 0.69, 0.847 -0.18
A/J m 0.767 0.0394   10 0.0125 0.0514 0.69, 0.826 -0.17
AKR/J f 0.926 0.0541   9 0.018 0.0584 0.847, 0.98 0.5
AKR/J m 0.921 0.0882   8 0.0312 0.0958 0.828, 1.08 0.44
BALB/cByJ f 0.898 0.153   10 0.0483 0.17 0.527, 1.03 0.39
BALB/cByJ m 0.771 0.329   10 0.104 0.426 -0.16
BTBR T+ Itpr3tf/J f 0.0 0.0   12 0.0 0.0 -3.15
BTBR T+ Itpr3tf/J m 0.00167 0.00408   6 0.00167 2.45 -3.23
C3H/HeJ f 0.911 0.105   10 0.0333 0.116 0.691, 1.01 0.44
C3H/HeJ m 0.823 0.0873   8 0.0309 0.106 0.706, 0.917 0.05
C57BL/6J f 1.0 0.0485   8 0.0171 0.0485 0.912, 1.06 0.79
C57BL/6J m 1.06 0.105   10 0.0333 0.0991 0.934, 1.32 1.0
C57L/J f 0.951 0.0903   10 0.0286 0.0949 0.788, 1.1 0.59
C57L/J m 0.973 0.0585   8 0.0207 0.0601 0.867, 1.03 0.65
C58/J f 0.926 0.0437   9 0.0146 0.0472 0.878, 1.01 0.5
C58/J m 0.941 0.0866   10 0.0274 0.0921 0.805, 1.1 0.52
CAST/EiJ f 0.694 0.0395   9 0.0132 0.057 0.614, 0.741 -0.42
CAST/EiJ m 0.704 0.087   9 0.029 0.124 0.548, 0.83 -0.43
DBA/2J f 0.722 0.0566   10 0.0179 0.0784 0.638, 0.828 -0.31
DBA/2J m 0.669 0.0878   8 0.0311 0.131 0.539, 0.818 -0.57
FVB/NJ f 1.06 0.0862   10 0.0273 0.0815 0.903, 1.17 1.02
FVB/NJ m 1.09 0.0644   11 0.0194 0.059 0.971, 1.18 1.12
MOLF/EiJ f 0.493 0.0411   8 0.0145 0.0833 0.419, 0.541 -1.21
MOLF/EiJ m 0.516 0.0215   6 0.00876 0.0416 0.486, 0.538 -1.18
NOD/ShiLtJ f 1.16 0.0498   12 0.0144 0.0428 1.08, 1.25 1.42
NOD/ShiLtJ m 1.09 0.101   12 0.0293 0.0931 0.867, 1.23 1.12
NZB/BlNJ f 0.727 0.0431   6 0.0176 0.0593 0.679, 0.801 -0.29
NZB/BlNJ m 0.717 0.0764   12 0.022 0.107 0.608, 0.865 -0.37
PERA/EiJ f 0.683 0.0492   10 0.0156 0.072 0.607, 0.739 -0.46
PERA/EiJ m 0.687 0.0574   12 0.0166 0.0836 0.587, 0.801 -0.49
PL/J f 0.951 0.0638   12 0.0184 0.0671 0.836, 1.05 0.59
PL/J m 0.953 0.0432   8 0.0153 0.0453 0.915, 1.03 0.57
SJL/J f 0.804 0.0723   8 0.0256 0.0898 0.71, 0.946 0.02
SJL/J m 0.795 0.12   12 0.0347 0.151 0.522, 0.896 -0.06
SM/J f 1.08 0.161   14 0.0431 0.149 0.635, 1.38 1.1
SM/J m 1.11 0.079   10 0.025 0.071 0.959, 1.21 1.2
SPRET/EiJ f 0.589 0.0135   5 0.00604 0.0229 0.567, 0.601 -0.83
SWR/J f 0.892 0.0411   10 0.013 0.0461 0.84, 0.948 0.36
SWR/J m 0.858 0.0864   10 0.0273 0.101 0.693, 0.96 0.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.5818 0.0425 0.6654 0.4982
129S1/SvImJ m 0.7632 0.0425 0.8468 0.6796
A/J f 0.7548 0.0475 0.8483 0.6612
A/J m 0.7673 0.0425 0.8509 0.6837
AKR/J f 0.9262 0.0448 1.0144 0.8381
AKR/J m 0.9214 0.0475 1.0149 0.8279
BALB/cByJ f 0.8985 0.0425 0.9821 0.8149
BALB/cByJ m 0.7711 0.0425 0.8547 0.6875
BTBR T+ Itpr3tf/J f 0.0 0.0388 0.0764 -0.0764
BTBR T+ Itpr3tf/J m 0.0017 0.0549 0.1097 -0.1063
C3H/HeJ f 0.9113 0.0425 0.9949 0.8277
C3H/HeJ m 0.8225 0.0475 0.916 0.729
C57BL/6J f 0.9998 0.0475 1.0933 0.9062
C57BL/6J m 1.0635 0.0425 1.1471 0.9799
C57L/J f 0.9512 0.0425 1.0348 0.8676
C57L/J m 0.9725 0.0475 1.066 0.879
C58/J f 0.926 0.0448 1.0142 0.8378
C58/J m 0.9406 0.0425 1.0242 0.857
CAST/EiJ f 0.694 0.0448 0.7822 0.6058
CAST/EiJ m 0.7042 0.0448 0.7924 0.6161
DBA/2J f 0.7224 0.0425 0.806 0.6388
DBA/2J m 0.6689 0.0475 0.7624 0.5754
FVB/NJ f 1.0573 0.0425 1.1409 0.9737
FVB/NJ m 1.0919 0.0405 1.1717 1.0122
MOLF/EiJ f 0.4934 0.0475 0.5869 0.3999
MOLF/EiJ m 0.5162 0.0549 0.6242 0.4082
NOD/ShiLtJ f 1.165 0.0388 1.2414 1.0886
NOD/ShiLtJ m 1.0886 0.0388 1.1649 1.0122
NZB/BlNJ f 0.7272 0.0549 0.8352 0.6192
NZB/BlNJ m 0.7167 0.0388 0.793 0.6403
PERA/EiJ f 0.6833 0.0425 0.7669 0.5997
PERA/EiJ m 0.6867 0.0388 0.763 0.6103
PL/J f 0.9507 0.0388 1.0271 0.8744
PL/J m 0.9531 0.0475 1.0466 0.8596
SJL/J f 0.8044 0.0475 0.8979 0.7109
SJL/J m 0.7947 0.0388 0.871 0.7183
SM/J f 1.0809 0.0359 1.1516 1.0102
SM/J m 1.1129 0.0425 1.1965 1.0293
SWR/J f 0.8916 0.0425 0.9752 0.808
SWR/J m 0.858 0.0425 0.9416 0.7744


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.6725 0.0301 0.7316 0.6134
A/J both 0.761 0.0319 0.8238 0.6983
AKR/J both 0.9238 0.0327 0.9881 0.8595
BALB/cByJ both 0.8348 0.0301 0.8939 0.7757
BTBR T+ Itpr3tf/J both 0.0008 0.0336 0.067 -0.0653
C3H/HeJ both 0.8669 0.0319 0.9296 0.8042
C57BL/6J both 1.0316 0.0319 1.0944 0.9689
C57L/J both 0.9619 0.0319 1.0246 0.8991
C58/J both 0.9333 0.0309 0.9941 0.8725
CAST/EiJ both 0.6991 0.0317 0.7615 0.6368
DBA/2J both 0.6956 0.0319 0.7584 0.6329
FVB/NJ both 1.0746 0.0294 1.1324 1.0168
MOLF/EiJ both 0.5048 0.0363 0.5762 0.4333
NOD/ShiLtJ both 1.1268 0.0275 1.1808 1.0728
NZB/BlNJ both 0.7219 0.0336 0.788 0.6558
PERA/EiJ both 0.685 0.0288 0.7416 0.6284
PL/J both 0.9519 0.0307 1.0123 0.8916
SJL/J both 0.7995 0.0307 0.8599 0.7392
SM/J both 1.0969 0.0278 1.1517 1.0422
SWR/J both 0.8748 0.0301 0.9339 0.8157




  GWAS USING LINEAR MIXED MODELS