ITP survival analysis: sulindac
Results are based on the use of pooled factor(s) that is/are stratified within the survival analysis model.
All test sites combined – female
Survival analysis details -- Female
Sul effect on survival,
females, test site = All
Log-rank test
chisq = 0.028
p = 0.8672
Wang-Allison test
odds ratio = 1.5299
p = 0.2301
Quantiles
Sul
Control
% difference
25% died before day:
764
767
0 %
Median lifespan (days)
852
868
-2 %
75% died before day:
963
958
+1 %
90% died before day:
1081
1060
+2 %
Max lifespan observed (days)
1178
1221
Number of mice at start
136
276
Animal censor events are denoted by + marks in the plot
All test sites combined – male
Survival analysis details -- Male
Sul effect on survival,
males, test site = All
Log-rank test
chisq = 0.1582
p = 0.6909
Wang-Allison test
odds ratio = 1.5791
p = 0.1779
Quantiles
Sul
Control
% difference
25% died before day:
490
447
+10 %
Median lifespan (days)
698
718
-3 %
75% died before day:
892
919
-3 %
90% died before day:
1037
1029
+1 %
Max lifespan observed (days)
1302
1258
Number of mice at start
144
285
Animal censor events are denoted by + marks in the plot
By individual test site:
TJL – female
TJL – female
Survival analysis details
Sul effect on survival,
females, test site = TJL
Log-rank test
chisq = 0.8315
p = 0.3618
Wang-Allison test
odds ratio = 2.5248
p = 0.0916
Quantiles
Sul
Control
% difference
25% died before day:
796
760
+5 %
Median lifespan (days)
874
870
0 %
75% died before day:
987
968
+2 %
90% died before day:
1127
1068
+6 %
Max lifespan observed (days)
1178
1209
Number of mice at start
48
96
Animal censor events are denoted by + marks in the plot
TJL – male
TJL – male
Survival analysis details
Sul effect on survival,
males, test site = TJL
Log-rank test
chisq = 0.3247
p = 0.5688
Wang-Allison test
odds ratio = 1.996
p = 0.245
Quantiles
Sul
Control
% difference
25% died before day:
490
488
0 %
Median lifespan (days)
710
748
-5 %
75% died before day:
936
949
-1 %
90% died before day:
1120
1079
+4 %
Max lifespan observed (days)
1191
1226
Number of mice at start
48
102
Animal censor events are denoted by + marks in the plot
UM – female
UM – female
Survival analysis details
Sul effect on survival,
females, test site = UM
Log-rank test
chisq = 4.9168
p = 0.0266
Wang-Allison test
odds ratio = 0.5278
p = 0.5483
Quantiles
Sul
Control
% difference
25% died before day:
726
820
-11 %
Median lifespan (days)
841
902
-7 %
75% died before day:
940
1000
-6 %
90% died before day:
1072
1098
-2 %
Max lifespan observed (days)
1161
1221
Number of mice at start
44
90
Animal censor events are denoted by + marks in the plot
UM – male
UM – male
Survival analysis details
Sul effect on survival,
males, test site = UM
Log-rank test
chisq = 0.0071
p = 0.933
Wang-Allison test
odds ratio = 1.5333
p = 0.5522
Quantiles
Sul
Control
% difference
25% died before day:
452
468
-3 %
Median lifespan (days)
696
790
-12 %
75% died before day:
940
933
+1 %
90% died before day:
1067
1019
+5 %
Max lifespan observed (days)
1302
1233
Number of mice at start
45
88
Animal censor events are denoted by + marks in the plot
UT – female
UT – female
Survival analysis details
Sul effect on survival,
females, test site = UT
Log-rank test
chisq = 1.7461
p = 0.1864
Wang-Allison test
odds ratio = 2.2285
p = 0.227
Quantiles
Sul
Control
% difference
25% died before day:
717
696
+3 %
Median lifespan (days)
850
824
+3 %
75% died before day:
980
937
+5 %
90% died before day:
1061
993
+7 %
Max lifespan observed (days)
1165
1198
Number of mice at start
44
90
Animal censor events are denoted by + marks in the plot
UT – male
UT – male
Survival analysis details
Sul effect on survival,
males, test site = UT
Log-rank test
chisq = 0.0007
p = 0.9785
Wang-Allison test
odds ratio = 1.2719
p = 0.7762
Quantiles
Sul
Control
% difference
25% died before day:
528
400
+32 %
Median lifespan (days)
678
676
0 %
75% died before day:
822
825
0 %
90% died before day:
969
963
+1 %
Max lifespan observed (days)
1142
1258
Number of mice at start
51
95
Animal censor events are denoted by + marks in the plot
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ITP data portal page for more information on
National Institute on Aging's Interventions Testing Program (ITP) including bibliography, data set downloads, and links to all available hosted data.
Statistical definitions