ITP survival analysis: resveratrol
Intervention:
resveratrol
dietary supplement
Trial code: Res
Dose: 300 ppm
initiated at age: 4 mo
Sex: both
Cohort: C2007
Results are based on the use of pooled factor(s) that is/are stratified within the survival analysis model.
All test sites combined – female
Survival analysis details -- Female
Res effect on survival,
females, test site = All
Log-rank test
chisq = 0.0259
p = 0.8722
Wang-Allison test
odds ratio = 0.5727
p = 0.1623
Quantiles
Res
Control
% difference
25% died before day:
807
753
+7 %
Median lifespan (days)
903
865
+4 %
75% died before day:
980
994
-1 %
90% died before day:
1086
1088
0 %
Max lifespan observed (days)
1374
1359
Number of mice at start
129
275
Animal censor events are denoted by + marks in the plot
All test sites combined – male
Survival analysis details -- Male
Res effect on survival,
males, test site = All
Log-rank test
chisq = 0.0017
p = 0.9674
Wang-Allison test
odds ratio = 0.719
p = 0.3999
Quantiles
Res
Control
% difference
25% died before day:
616
588
+5 %
Median lifespan (days)
812
784
+4 %
75% died before day:
968
954
+1 %
90% died before day:
1060
1074
-1 %
Max lifespan observed (days)
1186
1247
Number of mice at start
144
276
Animal censor events are denoted by + marks in the plot
By individual test site:
TJL – female
TJL – female
Survival analysis details
Res effect on survival,
females, test site = TJL
Log-rank test
chisq = 0.5994
p = 0.4388
Wang-Allison test
odds ratio = 0.9349
p = 1.0
Quantiles
Res
Control
% difference
25% died before day:
814
740
+10 %
Median lifespan (days)
938
860
+9 %
75% died before day:
998
1016
-2 %
90% died before day:
1111
1111
0 %
Max lifespan observed (days)
1374
1340
Number of mice at start
44
92
Animal censor events are denoted by + marks in the plot
TJL – male
TJL – male
Survival analysis details
Res effect on survival,
males, test site = TJL
Log-rank test
chisq = 0.4058
p = 0.5241
Wang-Allison test
odds ratio = 1.3139
p = 0.7713
Quantiles
Res
Control
% difference
25% died before day:
636
569
+12 %
Median lifespan (days)
754
728
+4 %
75% died before day:
941
923
+2 %
90% died before day:
1057
1039
+2 %
Max lifespan observed (days)
1177
1200
Number of mice at start
51
87
Animal censor events are denoted by + marks in the plot
UM – female
UM – female
Survival analysis details
Res effect on survival,
females, test site = UM
Log-rank test
chisq = 0.4069
p = 0.5235
Wang-Allison test
odds ratio = 0.5617
p = 0.5471
Quantiles
Res
Control
% difference
25% died before day:
853
767
+11 %
Median lifespan (days)
930
900
+3 %
75% died before day:
1003
999
0 %
90% died before day:
1101
1114
-1 %
Max lifespan observed (days)
1133
1359
Number of mice at start
42
91
Animal censor events are denoted by + marks in the plot
UM – male
UM – male
Survival analysis details
Res effect on survival,
males, test site = UM
Log-rank test
chisq = 0.8512
p = 0.3562
Wang-Allison test
odds ratio = 1.2425
p = 0.7776
Quantiles
Res
Control
% difference
25% died before day:
691
659
+5 %
Median lifespan (days)
869
793
+10 %
75% died before day:
1017
953
+7 %
90% died before day:
1102
1076
+2 %
Max lifespan observed (days)
1186
1191
Number of mice at start
51
93
Animal censor events are denoted by + marks in the plot
UT – female
UT – female
Survival analysis details
Res effect on survival,
females, test site = UT
Log-rank test
chisq = 1.4842
p = 0.2231
Wang-Allison test
odds ratio = 0.3274
p = 0.2245
Quantiles
Res
Control
% difference
25% died before day:
696
756
-8 %
Median lifespan (days)
833
840
-1 %
75% died before day:
945
962
-2 %
90% died before day:
984
1045
-6 %
Max lifespan observed (days)
1104
1261
Number of mice at start
43
92
Animal censor events are denoted by + marks in the plot
UT – male
UT – male
Survival analysis details
Res effect on survival,
males, test site = UT
Log-rank test
chisq = 3.0817
p = 0.0792
Wang-Allison test
odds ratio = 0.0
p = 0.0056
Quantiles
Res
Control
% difference
25% died before day:
561
584
-4 %
Median lifespan (days)
821
810
+1 %
75% died before day:
942
1010
-7 %
90% died before day:
995
1132
-12 %
Max lifespan observed (days)
1060
1247
Number of mice at start
42
96
Animal censor events are denoted by + marks in the plot
See our
ITP data portal page for more information on
National Institute on Aging's Interventions Testing Program (ITP) including bibliography, data set downloads, and links to all available hosted data.
Statistical definitions