ITP survival analysis: MitoQ
Results are based on the use of pooled factor(s) that is/are stratified within the survival analysis model.
All test sites combined – female
Survival analysis details -- Female
MitoQ effect on survival,
females, test site = All
Log-rank test
chisq = 0.1818
p = 0.6698
Wang-Allison test
odds ratio = 1.0124
p = 1.0
Quantiles
MitoQ
Control
% difference
25% died before day:
775
786
-1 %
Median lifespan (days)
890
904
-2 %
75% died before day:
1002
1016
-1 %
90% died before day:
1105
1095
+1 %
Max lifespan observed (days)
1293
1396
Number of mice at start
136
274
Animal censor events are denoted by + marks in the plot
All test sites combined – male
Survival analysis details -- Male
MitoQ effect on survival,
males, test site = All
Log-rank test
chisq = 0.0127
p = 0.9102
Wang-Allison test
odds ratio = 1.135
p = 0.7349
Quantiles
MitoQ
Control
% difference
25% died before day:
559
581
-4 %
Median lifespan (days)
784
772
+2 %
75% died before day:
926
918
+1 %
90% died before day:
1066
1049
+2 %
Max lifespan observed (days)
1366
1237
Number of mice at start
145
264
Animal censor events are denoted by + marks in the plot
By individual test site:
TJL – female
TJL – female
Survival analysis details
MitoQ effect on survival,
females, test site = TJL
Log-rank test
chisq = 0.5881
p = 0.4431
Wang-Allison test
odds ratio = 1.8482
p = 0.2625
Quantiles
MitoQ
Control
% difference
25% died before day:
788
785
0 %
Median lifespan (days)
968
928
+4 %
75% died before day:
1064
1043
+2 %
90% died before day:
1205
1156
+4 %
Max lifespan observed (days)
1293
1396
Number of mice at start
48
95
Animal censor events are denoted by + marks in the plot
TJL – male
TJL – male
Survival analysis details
MitoQ effect on survival,
males, test site = TJL
Log-rank test
chisq = 0.2705
p = 0.603
Wang-Allison test
odds ratio = 1.5589
p = 0.4132
Quantiles
MitoQ
Control
% difference
25% died before day:
559
608
-8 %
Median lifespan (days)
800
818
-2 %
75% died before day:
960
942
+2 %
90% died before day:
1116
1061
+5 %
Max lifespan observed (days)
1366
1237
Number of mice at start
54
92
Animal censor events are denoted by + marks in the plot
UM – female
UM – female
Survival analysis details
MitoQ effect on survival,
females, test site = UM
Log-rank test
chisq = 0.3484
p = 0.555
Wang-Allison test
odds ratio = 0.3526
p = 0.2216
Quantiles
MitoQ
Control
% difference
25% died before day:
776
791
-2 %
Median lifespan (days)
884
899
-2 %
75% died before day:
990
992
0 %
90% died before day:
1035
1079
-4 %
Max lifespan observed (days)
1220
1291
Number of mice at start
44
91
Animal censor events are denoted by + marks in the plot
UM – male
UM – male
Survival analysis details
MitoQ effect on survival,
males, test site = UM
Log-rank test
chisq = 0.7987
p = 0.3715
Wang-Allison test
odds ratio = 0.782
p = 0.7698
Quantiles
MitoQ
Control
% difference
25% died before day:
472
601
-21 %
Median lifespan (days)
769
740
+4 %
75% died before day:
876
905
-3 %
90% died before day:
1021
1027
-1 %
Max lifespan observed (days)
1133
1231
Number of mice at start
45
81
Animal censor events are denoted by + marks in the plot
UT – female
UT – female
Survival analysis details
MitoQ effect on survival,
females, test site = UT
Log-rank test
chisq = 1.0151
p = 0.3137
Wang-Allison test
odds ratio = 1.1243
p = 1.0
Quantiles
MitoQ
Control
% difference
25% died before day:
753
786
-4 %
Median lifespan (days)
870
892
-2 %
75% died before day:
948
1014
-7 %
90% died before day:
1068
1078
-1 %
Max lifespan observed (days)
1206
1280
Number of mice at start
44
88
Animal censor events are denoted by + marks in the plot
UT – male
UT – male
Survival analysis details
MitoQ effect on survival,
males, test site = UT
Log-rank test
chisq = 0.2329
p = 0.6294
Wang-Allison test
odds ratio = 1.1102
p = 1.0
Quantiles
MitoQ
Control
% difference
25% died before day:
636
500
+27 %
Median lifespan (days)
784
786
0 %
75% died before day:
906
888
+2 %
90% died before day:
1066
1025
+4 %
Max lifespan observed (days)
1190
1220
Number of mice at start
46
91
Animal censor events are denoted by + marks in the plot
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ITP data portal page for more information on
National Institute on Aging's Interventions Testing Program (ITP) including bibliography, data set downloads, and links to all available hosted data.
Statistical definitions