ITP survival analysis: candesartan cilexetil
Results are based on the use of pooled factor(s) that is/are stratified within the survival analysis model.
All test sites combined – female
Survival analysis details -- Female
CC effect on survival,
females, test site = All
Log-rank test
chisq = 1.4104
p = 0.235
Wang-Allison test
odds ratio = 1.8535
p = 0.0589
Quantiles
CC
Control
% difference
25% died before day:
782
790
-1 %
Median lifespan (days)
870
875
-1 %
75% died before day:
1005
975
+3 %
90% died before day:
1087
1055
+3 %
Max lifespan observed (days)
1295
1339
Number of mice at start
132
303
Animal censor events are denoted by + marks in the plot
All test sites combined – male
Survival analysis details -- Male
CC effect on survival,
males, test site = All
Log-rank test
chisq = 0.8025
p = 0.3704
Wang-Allison test
odds ratio = 1.1198
p = 0.7327
Quantiles
CC
Control
% difference
25% died before day:
670
608
+10 %
Median lifespan (days)
817
782
+4 %
75% died before day:
939
935
0 %
90% died before day:
1055
1055
0 %
Max lifespan observed (days)
1306
1264
Number of mice at start
138
275
Animal censor events are denoted by + marks in the plot
By individual test site:
TJL – female
TJL – female
Survival analysis details
CC effect on survival,
females, test site = TJL
Log-rank test
chisq = 3.618
p = 0.0572
Wang-Allison test
odds ratio = 2.4966
p = 0.1454
Quantiles
CC
Control
% difference
25% died before day:
773
816
-5 %
Median lifespan (days)
896
883
+1 %
75% died before day:
1045
971
+8 %
90% died before day:
1198
1057
+13 %
Max lifespan observed (days)
1295
1230
Number of mice at start
48
95
Animal censor events are denoted by + marks in the plot
TJL – male
TJL – male
Survival analysis details
CC effect on survival,
males, test site = TJL
Log-rank test
chisq = 3.8423
p = 0.05
Wang-Allison test
odds ratio = 2.2463
p = 0.1582
Quantiles
CC
Control
% difference
25% died before day:
678
608
+12 %
Median lifespan (days)
824
749
+10 %
75% died before day:
958
891
+8 %
90% died before day:
1059
1005
+5 %
Max lifespan observed (days)
1306
1262
Number of mice at start
52
94
Animal censor events are denoted by + marks in the plot
UM – female
UM – female
Survival analysis details
CC effect on survival,
females, test site = UM
Log-rank test
chisq = 0.8583
p = 0.3542
Wang-Allison test
odds ratio = 1.1808
p = 0.7697
Quantiles
CC
Control
% difference
25% died before day:
753
788
-4 %
Median lifespan (days)
866
858
+1 %
75% died before day:
932
961
-3 %
90% died before day:
1038
1034
0 %
Max lifespan observed (days)
1124
1189
Number of mice at start
44
92
Animal censor events are denoted by + marks in the plot
UM – male
UM – male
Survival analysis details
CC effect on survival,
males, test site = UM
Log-rank test
chisq = 0.0435
p = 0.8348
Wang-Allison test
odds ratio = 0.4026
p = 0.335
Quantiles
CC
Control
% difference
25% died before day:
712
534
+33 %
Median lifespan (days)
866
814
+6 %
75% died before day:
974
996
-2 %
90% died before day:
1052
1071
-2 %
Max lifespan observed (days)
1216
1258
Number of mice at start
38
82
Animal censor events are denoted by + marks in the plot
UT – female
UT – female
Survival analysis details
CC effect on survival,
females, test site = UT
Log-rank test
chisq = 0.9308
p = 0.3347
Wang-Allison test
odds ratio = 2.048
p = 0.2188
Quantiles
CC
Control
% difference
25% died before day:
793
774
+2 %
Median lifespan (days)
876
882
-1 %
75% died before day:
1010
984
+3 %
90% died before day:
1124
1058
+6 %
Max lifespan observed (days)
1268
1339
Number of mice at start
40
116
Animal censor events are denoted by + marks in the plot
UT – male
UT – male
Survival analysis details
CC effect on survival,
males, test site = UT
Log-rank test
chisq = 0.5601
p = 0.4542
Wang-Allison test
odds ratio = 1.0346
p = 1.0
Quantiles
CC
Control
% difference
25% died before day:
618
640
-3 %
Median lifespan (days)
770
799
-4 %
75% died before day:
880
936
-6 %
90% died before day:
1055
1064
-1 %
Max lifespan observed (days)
1159
1264
Number of mice at start
48
99
Animal censor events are denoted by + marks in the plot
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National Institute on Aging's Interventions Testing Program (ITP) including bibliography, data set downloads, and links to all available hosted data.
Statistical definitions