| Data set | Procedure | What's in this data set | Panel | Sex | Age (weeks) | Year |
|---|---|---|---|---|---|---|
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genotype assessment | Gpr84 allele assessment. PCR, sequencing. | inbred w/CC8 (58) | both | 6wks | 2013 |
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health assessment
with Plasmodium berghei |
Susceptibility, Plasmodium berghei (malaria). Parasitemia in blood and distribution in brain, spleen, lungs, liver. | inbred (31) | both | 8-12wks | 2010 |
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|
genotyping | SNP profiling, 131,000+ genomic locations, 1-19,X. | inbred (89) | 2009 | ||
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genotyping | SNP profiling, 470,000+ genomic locations, 1-19,X,Y,MT. | inbred (142) | m | 2014 | |
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body size and weight | Body weight and length. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
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complete blood count | Hematology. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
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DXA | Body mass, fat mass, lean mass, bone mineral density. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
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lipid profile | Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
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metabolic panel | Clinical blood chemistry (plasma). 4h fast. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
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electroretinography | Photoreceptor measures: rod Awave, Bwave, cone Bwave. | inbred (17) | both | 10-13wks | 2008 |
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organ dimensions | Eye diameter. | inbred (17) | both | 10-13wks | 2008 |
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body weight
with ethanol |
Body weight | inbred (22) | both | 9-17wks | 2003 |
|
|
rotarod
with ethanol |
Baseline and ethanol i.p. 3 fixed speeds (several doses) and accelerating. | inbred (22) | both | 9-17wks | 2003 |
|
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alcohol quantification
with ethanol |
Blood alcohol concentration after ethanol 2 g/kg i.p., several timepoints. | inbred (21) | both | 9-17wks | 2003 |
|
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dowel balance test
with ethanol |
Latency to fall 0 min and 30 min post-injection, 2 widths. Ethanol 2 g/kg. | inbred (21) | both | 9-17wks | 2003 |
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grip strength
with ethanol |
Baseline vs. 30 min after ethanol 2 g/kg i.p. | inbred (21) | both | 9-17wks | 2003 |
|
|
vertical wire mesh
with ethanol |
Latency to fall 30 min post-injection. Ethanol 2 g/kg i.p. | inbred (21) | both | 9-17wks | 2003 |
|
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DXA | Body mass, fat mass, lean mass, bone mineral density and content, craniofacial dimensions. | inbred w/CC7 (30) | both | 15-16wks | 2002 |
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hormone quantification | Osteocalcin, insulin-like growth factor 1. | inbred w/CC7 (30) | both | 15-16wks | 2002 |
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metabolic panel | Thyroxine (serum). | inbred w/CC7 (30) | both | 15-16wks | 2002 |
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body weight | Body weight | inbred (14) | both | 9-12wks | 2003 |
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bone dimensions | Craniofacial bone dimensions. | inbred (14) | both | 9-12wks | 2003 |
|
|
bottle choice test
with ethanol |
Voluntary consumption of ethanol, and ethanol with saccharin (several doses in water). | inbred (22) | both | 8-12wks | 2007 |
|
|
complete blood count
with ENU |
Hematology. | inbred (20) | both | 9wks; 12-64wks | 2006 |
|
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histopathology
with ENU |
Tumor growth frequency rates. ENU mutagen 100 mg/kg vs. control. | inbred (20) | both | 9wks; 12-64wks | 2006 |
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ophthalmoscopy | Retinal fundoscopic examination. | inbred w/CC7 (41) | both | 6-7wks | 2008 |
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slit lamp | Eye morphology. Frequency rates of disorders. | inbred w/CC7 (41) | both | 6-7wks | 2008 |
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colony observation | Appearance, coat color | inbred (61) | both | 2006 | |
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ABR test | Auditory brainstem response. | inbred (51) | both | 3-12wks and 15-72wks | 2000 |
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hole board test | Head dipping and other activity measures, hole board with and without objects in two of the holes. 10 min test. | inbred (14) | both | 8wks | 2006 |
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monitoring system | Activity in a novel environment. Distance traveled, number of rears. 30 min test. | inbred (14) | both | 8wks | 2006 |
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two chamber assay | Novel environment preference. Activity in familiar and novel compartments. 20 min test. | inbred (14) | both | 8wks | 2006 |
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Y-maze | Spontaneous alternation. | inbred (14) | both | 8wks | 2006 |
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three chamber assay | Sociability and preference for social novelty. Autism-relevant behaviors. | inbred (17) | m | 6-7wks | 2008 |
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body weight
with high-fat diet |
High-fat diet for 8wks. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
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DXA
with high-fat diet |
Body mass, fat mass, lean mass, bone mineral density and content after 8wks on high-fat diet. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
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|
hormone quantification
with high-fat diet |
Insulin and leptin after 18wks on high-fat diet. Multiple readings per animal were averaged. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
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|
metabolic panel
with high-fat diet |
Glucose (plasma). Baseline vs. high-fat diet (17wks). 4h fast. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
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|
body weight
with high-fat diet |
Baseline vs. high-fat diet for 8wks. | inbred (44) | both | 15-19wks | 2000 |
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histopathology
with high-fat diet |
Gallstone, gallbladder, and atherosclerosis lesion histopathology after 8wks on high-fat diet. | inbred (44) | both | 15-19wks | 2000 |
|
|
lipid profile
with high-fat diet |
Cholesterol, HDL, non-HDL. 4h fast, plasma. Hepatic lipids. 8wks on high-fat diet. | inbred (44) | both | 15-19wks | 2000 |
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|
metabolic panel
with high-fat diet |
Alanine transaminase, bile salts (plasma) after 8wks on high-fat diet. 4h fast. | inbred (44) | both | 15-19wks | 2000 |
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organ dimensions
with high-fat diet |
Gallbladder volume after 8wks on high-fat diet. | inbred (44) | both | 15-19wks | 2000 |
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organ weights
with high-fat diet |
Liver weight after 8wks on high-fat diet. | inbred (44) | both | 15-19wks | 2000 |
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|
histopathology
with high-fat diet |
Aortic lesion size histopathology. Baseline vs. high-fat diet (17wks). | inbred w/CC7 (43) | both | 7-9wks, 24-27wks | 2002 |
|
|
lipid profile
with high-fat diet |
Cholesterol, HDL, non-HDL, triglycerides. Baseline vs. high-fat diet (17wks). 4h fast, plasma. | inbred w/CC7 (43) | both | 7-9wks, 24-27wks | 2002 |
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lipid profile | Cholesterol, HDL, non-HDL, triglycerides. 4h fast, plasma. | inbred w/CC7 (43) | both | 10wks | 2002 |
|
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coagulation test | Fibrinogen. | inbred w/CC7 (43) | both | 10wks | 2001 |
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complete blood count | Hematology. | inbred w/CC7 (43) | both | 10wks | 2001 |
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body weight | Body weight | inbred (32) | m | 7-9wks | 2007 |
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hormone quantification | Corticosterone (serum). | inbred (32) | m | 7-9wks | 2007 |
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open field test | Locomotor and anxiety-related behavior. 10 min test. | inbred (32) | m | 7-9wks | 2007 |
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tail suspension test | Immobility percentage. | inbred (32) | m | 7-9wks | 2007 |
|
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body weight
with cocaine |
Body weight | inbred (45) | m | 8-11wks | 2015 |
|
|
open field test
with cocaine |
Locomotor activity. Baseline (saline) vs. cocaine 20 mg/kg i.p. 30 min test. | inbred (45) | m | 8-11wks | 2015 |
|
|
forced swim test
with ovariectomy |
Mice with ovariectomy surgery vs. controls (sham surgery), 6 min test. | inbred (37) | f | 8-10wks | 2016 |
|
|
open field test
with ovariectomy |
Locomotor activity and exploratory behavior. Mice with ovariectomy surgery vs. controls (sham surgery), 10 min test. | inbred (37) | f | 8-10wks | 2016 |
|
|
biomarker quantification
with acetaminophen |
Liver cytochrome isoforms. Acetaminophen vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
|
histopathology
with acetaminophen |
Liver histopathology, necrosis after acetaminophen vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
|
metabolic panel
with acetaminophen |
Blood urea nitrogen, alanine transaminase, aspartate transaminase (serum), liver enzyme homeostasis. Acetaminophen (several doses) vs. control, several timepoints post-Rx. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
|
metabolite quantification
with acetaminophen |
Liver protein homeostasis. Acetaminophen vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
|
organ weights
with acetaminophen |
Liver weight after acetaminophen (several doses) vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
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body weight | Body weight | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
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bottle choice test | Various salt solutions (several concentrations) vs. water. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
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DXA | Body mass, fat mass, lean mass, bone mineral density and content. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
|
metabolic panel | Ionized and total blood calcium, blood pH. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
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monitoring system | Bleeding time to collect approx 30 µL. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
|
genotyping | SNP profiling, 132,000+ genomic locations, 1-19,X | HMDP (248) | both | 2018 | |
|
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elevated plus maze | Locomotor, exploratory, and anxiety-related behavior. | inbred (21) | both | 9, 12 wks | 2003 |
|
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histopathology | Corpus callosum, hippocampus, anterior commisure. | inbred (21) | both | 9, 12 wks | 2003 |
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open field test | Locomotor, exploratory, and anxiety-related behavior. 5 min test. | inbred (21) | both | 9, 12 wks | 2003 |
|
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organ weights | Brain weight. | inbred (21) | both | 9, 12 wks | 2003 |
|
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behavior observation | Wildness scoring during various phenotyping tests. | inbred (21) | both | 10-12wks | 2003 |
|
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acoustic startle test | Acoustic startle response, prepulse inhibition. | inbred w/CC7 (40) | both | 5-6wks | 2002 |
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body weight | Body weight | inbred w/CC7 (40) | both | 5-6wks | 2002 |
|
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elevated plus maze | Locomotor activity. | inbred (38) | both | 12-14wks | 2010 |
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light-dark box | Light-dark test. Anxiety-related behavior. | inbred (38) | both | 12-14wks | 2010 |
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open field test | Locomotor activity. | inbred (38) | both | 12-14wks | 2010 |
|
|
immune cell quantification
with BEZ235, doxorubicin, idarubicin, selumetinib |
In vitro study of 4 cancer chemotherapies (BEZ235, doxorubicin, idarubicin, selumetinib) vs. control. Effect on immune cells. Normalized data. | inbred w/CC7 (36) | m | 10wks | 2015 |
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tympanometry | Middle ear function. | inbred (61) | both | 15-51d | 2008 |