Tarantino2: Behavioral effects of estrogen depletion in females of 37 inbred strains of mice (2016)

Schoenrock SA, Oreper D, Young N, Ervin RB, Bogue MA, Valdar W, Tarantino LM. Ovariectomy results in inbred strain-specific increases in anxiety-like behavior in mice. Physiol Behav. 2016 Dec 1;167:404-412. doi: 10.1016/j.physbeh.2016.09.026. Epub 2016 Sep 29.   PubMed 27693591  


         
A study of mice subjected to ovariectomy vs. controls subjected to sham surgery.

Procedures conducted:
• open field test  Locomotor activity and exploratory behavior. Mice with ovariectomy surgery vs. controls (sham surgery), 10 min test.
• forced swim test  Mice with ovariectomy surgery vs. controls (sham surgery), 6 min test.

Tarantino2 downloads
• Download Tarantino2 project data set     animal data, as uploaded
• Download Tarantino2 animal data matrix     with factor-related expansion applied as necessary
• Download Tarantino2 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Lisa M Tarantino       University of North Carolina,  Chapel Hill, NC
Participants Schoenrock SA, Young N, Ervin RB
ContactLisa M Tarantino     lisat@med.unc.edu     Lab web site
AcknowledgementsFunding provided by Foundation of Hope for Research and Treatment of Mental Illness
Project type Phenotype strain survey data set
MPD identifiersTarantino2     MPD:506
Data changelog No updates/corrections.       Initial release date: 01/2017.
Formatted citation
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Mice: inbred   37 strains   ♀   age 8-10wks   2 experimental groups

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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
    Tarantino2 open field test ovariectomy distance traveled, 10 min test   [cm]  OFT_distance   50601     control    ovariectomy inbred 37 f 10-12wks N=9
    Tarantino2 open field test ovariectomy time spent mobile, 10 min test   [s]  OFT_movement   50606     control    ovariectomy inbred 37 f 10-12wks N=9
    Tarantino2 open field test ovariectomy number of vertical movements, 10 min teste   [n]  OFT_vertical   50611     control    ovariectomy inbred 37 f 10-12wks N=9
    Tarantino2 open field test ovariectomy distance traveled in center of arena, 10 min test   [cm]  OFT_center_distance   50616     control    ovariectomy inbred 37 f 10-12wks N=9
    Tarantino2 open field test ovariectomy duration in center of arena, 10 min test   [s]  OFT_center_duration   50621     control    ovariectomy inbred 37 f 10-12wks N=9
    Tarantino2 open field test ovariectomy percentage of time spent in center of arena, 10 min test   [%]  OFT_center_duration_pct   50626     control    ovariectomy inbred 37 f 10-12wks N=9
    Tarantino2 open field test ovariectomy distance traveled in periphery of arena, 10 min test   [cm]  OFT_thigmotaxis   50631     control    ovariectomy inbred 37 f 10-12wks N=9
    Tarantino2 forced swim test ovariectomy percentage of time spent immobile, 6 min test   [%]  FST_immobility   50636     control    ovariectomy inbred 36 f 10-12wks N=8
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