MPD: Data set: Tarantino2

Schoenrock SA, Oreper D, Young N, Ervin RB, Bogue MA, Valdar W, Tarantino LM. Ovariectomy results in inbred strain-specific increases in anxiety-like behavior in mice. Physiol Behav. 2016 Dec 1;167:404-412. doi: 10.1016/j.physbeh.2016.09.026. Epub 2016 Sep 29. PubMed 27693591

A study of mice subjected to ovariectomy vs. controls subjected to sham surgery.

Procedures conducted:

• open field test		Locomotor activity and exploratory behavior. Mice with ovariectomy surgery vs. controls (sham surgery), 10 min test.
• forced swim test		Mice with ovariectomy surgery vs. controls (sham surgery), 6 min test.

Tarantino2 downloads
• Download Tarantino2 project data set animal data, as uploaded
• Download Tarantino2 animal data matrix with factor-related expansion applied as necessary
• Download Tarantino2 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Tarantino2 measures:

MP:0001362 abnormal anxiety-related response
MP:0001392 abnormal locomotor behavior
MP:0003360 abnormal depression-related behavior
MP:0013189 abnormal exploration in a new environment
VT:0001392 locomotor behavior trait
VT:0010471 exploratory behavior trait
VT:0010716 anxiety-related behavior trait
VT:0015015 depression-related behavior trait

Investigators	Lisa M Tarantino University of North Carolina, Chapel Hill, NC
Participants	Schoenrock SA, Young N, Ervin RB
Contact	Lisa M Tarantino lisat@med.unc.edu Lab web site
Acknowledgements	Funding provided by Foundation of Hope for Research and Treatment of Mental Illness
Project type	Phenotype strain survey data set
MPD identifiers	Tarantino2 MPD:506
Data changelog	No updates/corrections. Initial release date: 01/2017.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Tarantino2:1	Tarantino2	open field test	ovariectomy	distance traveled, 10 min test [cm] OFT_distance 50601 control ovariectomy	inbred	37	f	10-12wks	N=9

Tarantino2:6	Tarantino2	open field test	ovariectomy	time spent mobile, 10 min test [s] OFT_movement 50606 control ovariectomy	inbred	37	f	10-12wks	N=9

Tarantino2:11	Tarantino2	open field test	ovariectomy	number of vertical movements, 10 min teste [n] OFT_vertical 50611 control ovariectomy	inbred	37	f	10-12wks	N=9

Tarantino2:16	Tarantino2	open field test	ovariectomy	distance traveled in center of arena, 10 min test [cm] OFT_center_distance 50616 control ovariectomy	inbred	37	f	10-12wks	N=9

Tarantino2:21	Tarantino2	open field test	ovariectomy	duration in center of arena, 10 min test [s] OFT_center_duration 50621 control ovariectomy	inbred	37	f	10-12wks	N=9

Tarantino2:26	Tarantino2	open field test	ovariectomy	percentage of time spent in center of arena, 10 min test [%] OFT_center_duration_pct 50626 control ovariectomy	inbred	37	f	10-12wks	N=9

Tarantino2:31	Tarantino2	open field test	ovariectomy	distance traveled in periphery of arena, 10 min test [cm] OFT_thigmotaxis 50631 control ovariectomy	inbred	37	f	10-12wks	N=9

Tarantino2:36	Tarantino2	forced swim test	ovariectomy	percentage of time spent immobile, 6 min test [%] FST_immobility 50636 control ovariectomy	inbred	36	f	10-12wks	N=8

Tarantino2: Behavioral effects of estrogen depletion in females of 37 inbred strains of mice (2016)