MPD: Data set: Spijker1

Loos M, Staal J, Pattij T; Neuro-BSIK Mouse Phenomics Consortium, Smit AB, Spijker S. Independent genetic loci for sensorimotor gating and attentional performance in BXD recombinant inbred strains. Genes Brain Behav. 2012 Mar;11(2):147-56. doi: 10.1111/j.1601-183X.2011.00754.x. Epub 2011 Dec 13. PubMed 22098762

Procedures conducted:

• acoustic startle test		Acoustic startle response, prepulse inhibition.
• choice serial reaction time task		Choice serial reaction time task. Impulsivity, attention, cognitive flexibility behavior.

Spijker1 downloads
• Download Spijker1 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Spijker1 measures:

MA:0000167 central nervous system
MA:0002443 auditory system
MP:0001486 abnormal startle reflex
MP:0002063 abnormal learning/memory/conditioning
MP:0002803 abnormal operant conditioning behavior
MP:0003088 abnormal prepulse inhibition
MP:0010698 abnormal impulsive behavior control
VT:0002063 learning/memory/conditioning trait
VT:0002634 sensorimotor gating trait
VT:0003088 prepulse inhibition trait
VT:0010473 impulsivity behavior trait
VT:0010531 operant conditioning behavior trait
VT:0010725 startle reflex trait

Investigators	Sabine Spijker VU University Amsterdam, Amsterdam NETHERLANDS
Participants	Loos M, Staal J, Pattij T, Smit AB, Neuro-BSIK Mouse Phenomics Consortium
Contact	Sabine Spijker sabine.spijker@vu.nl Lab web site
Project type	Phenotype strain survey data set
MPD identifiers	Spijker1 MPD:406
Data changelog	No updates/corrections. Initial release date: 07/2012.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Spijker1:1	Spijker1	acoustic startle test	(none)	acoustic startle response (ASR) [amplitude] ASR 40601 65dB 70dB 75dB 80dB 90dB 100dB 110dB 120dB	BXD w/par	39	m	8wks	N=11

Spijker1:13	Spijker1	acoustic startle test	(none)	prepulse inhibition (PPI), 120 dB startle intensity [%] PPI 40613 120 dB startle intensity with prepulse stimulus: 65dB 70dB 75dB 80dB	BXD w/par	36	m	8wks	N=9

Spijker1:17	Spijker1	acoustic startle test	(none)	prepulse intensity 10 dB lower than startle threshold [amplitude] PPI_belowST 40617	BXD w/par	36	m	8wks	N=9

Spijker1:18	Spijker1	acoustic startle test	(none)	startle threshold, minimum stimulus intensity where startle is significant compared to null period [dB] startle_threshold 40618	BXD w/par	39	m	8wks	N=11

Spijker1:19	Spijker1	choice serial reaction time task	(none)	percentage of total Reponses that are correct, stimulus duration fixed, 1s [%] accuracy_SD1 40619	BXD w/par	43	m	8wks	N=13

Spijker1:20	Spijker1	choice serial reaction time task	(none)	percentage of events that are omission errors, stimulus duration fixed, 1s [%] omission_SD1 40620	BXD w/par	43	m	8wks	N=13

Spijker1:21	Spijker1	choice serial reaction time task	(none)	correct response latency, stimulus duration fixed, 1s [s] latency_correct 40621	BXD w/par	43	m	8wks	N=13

Spijker1:22	Spijker1	choice serial reaction time task	(none)	mode of correct response latencies, stimulus duration fixed, 1s [s] latency_mode 40622	BXD w/par	43	m	8wks	N=13

Spijker1:23	Spijker1	choice serial reaction time task	(none)	individual variability of correct response latency [s] variability_SD1 40623	BXD w/par	43	m	8wks	N=13

Spijker1:24	Spijker1	choice serial reaction time task	(none)	latency between correct response and head entry detected in food magazine, stimulus duration fixed, 1s [s] latency_reward 40624	BXD w/par	43	m	8wks	N=13

Spijker1:25	Spijker1	choice serial reaction time task	(none)	number of initiated trials, stimulus duration 1s [n] trials_initiated 40625	BXD w/par	43	m	8wks	N=13

Spijker1:26	Spijker1	choice serial reaction time task	(none)	percentage of total responses that are correct, stimulus duration variable [%] accuracy_SDvar 40626	BXD w/par	43	m	8wks	N=13

Spijker1:27	Spijker1	choice serial reaction time task	(none)	percentage of events that are omission errors, stimulus duration variable [%] omission_SDvar 40627	BXD w/par	43	m	8wks	N=13

Spijker1: Sensorimotor gating and attentional performance in males of 45 BXD recombinant inbred and other mouse strains (2011)