Acclimation & testing periods
Vendor Inbred strains of C57BL/6J and C3HeB/FeJ mice were obtained from the breeding colonies of the GSF-National Research Center for Environment and Health; 129S2/SvPasCrl and BALB/cByJ mice were purchased from Charles River (Sulzfeld, Germany). Ages Mice were 4, 6, 8, 11, 13*, and 15 wks of age on the day of testing. Feed Ad libitum Water Ad libitum Housing The mice were housed in the animal facilities of the GSF in groups of three to five animals Bedding Wood fibre (Altromin, Lage, Germany) Photoperiod 12h/12h light/dark cycle Health status The use of animals was in accordance with the German Law of Animal Protection, the ARVO Statement for the Use of Animals in Ophthalmic and Vision Research, and the tenets of the Declaration of Helsinki.
* 13 wk data were accessioned as MPD measurements and are eligible for analysis with MPD tools.